iiinova — where your digital self keeps evolving

Reposted by Icahn Genomics Institute

Sinai Immuno @sinaiimmuno.bsky.social · 19/02/2026

The immune system profoundly shapes aging as it interacts with every organ. New single-cell & spatial tools now map where this relationship breaks down and where interventions support healthy longevity. More @ Immunoschool Program: immunoschool.org Register (free): www.eventbrite.com/e/internatio...

133

Reposted by Icahn Genomics Institute

Sinai Immuno @sinaiimmuno.bsky.social · 18/02/2026

3 days. Global faculty and learners of all career stages. Aging, immunity and translation at the cutting edge. Save your spot: www.eventbrite.com/e/internatio... Explore the program: immunoschool.org The second speaker will be Vishwa Deep Dixit of the Yale Univertsity Center for Research on Aging

044

Reposted by Icahn Genomics Institute

Sinai Immuno @sinaiimmuno.bsky.social · 16/02/2026

📣 Immunoschool 2026 is open for registration 📣 Explore how immunotherapy can promote healthy longevity, from targeting senescent cells to rejuvenating exhausted immunity and reducing inflammaging. FREE, online March 23–25. Program: immunoschool.org Register: www.eventbrite.com/e/internatio...

043

Reposted by Icahn Genomics Institute

Sinai Immuno @sinaiimmuno.bsky.social · 13/01/2026

New **RESOURCE** in @natcancer.nature.com - a landmark single-cell Immune Atlas of multiple myeloma—1.3M+ bone marrow cells from 337 patients. Led by the Immune Atlas Consortium with major contributions from Sacha Gnjatic, @edgargk.bsky.social & HIMC profiling teams 🧐 www.nature.com/articles/s43...

174

Icahn Genomics Institute @icahngenomics.bsky.social · 14/11/2025

🧬 mRNA has emerged as a powerful new class of therapeutic molecules—extending far beyond vaccines to cancer immunotherapy, protein replacement, and gene editing. 🧩 But designing mRNAs with strong, lasting protein expression remains a major challenge.

141

Reposted by Icahn Genomics Institute

BrownLab @Mt.Sinai @brownlab1.bsky.social · 17/10/2025

Our new review in @natbiomedeng.nature.com is out! RNA-loaded lipid nanoparticles (LNPs) have huge potential—but their strong liver and immune cell uptake has mostly confined them to vaccines and liver therapies. We explore how to move beyond those limits. free to read 🔗 rdcu.be/eLxGs

rdcu.be

Targeting and tracking mRNA lipid nanoparticles at the particle, transcript and protein level

Nature Biomedical Engineering - This Review explores strategies for targeting and tracking RNA-LNP drugs, monitoring their in vivo behaviour, enhancing tissue-specific delivery, and using synthetic...

13511

Reposted by Icahn Genomics Institute

Sinai Immuno @sinaiimmuno.bsky.social · 18/09/2025

📝NEW STUDY📝 Cancer's first punch when battling the immune system may be rewiring myeloid progenitors in bone marrow so they become suppressive tumor macrophages blunting T-cell attacks. Find out how in @nature.com from @samhegde.bsky.social & @miriammerad.bsky.social 🧐 www.nature.com/articles/s41...

nature.com

Myeloid progenitor dysregulation fuels immunosuppressive macrophages in tumours - Nature

An understanding of the molecular mechanisms promoting the generation of immunoregulatory and tumour-promoting monocytes and macrophages is key to breaking the cycle of tumour myelopoiesis and develop...

0145