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Juliane Nguyen

@julienguyenlab.bsky.social
683 followers 596 following 14 posts

Professor & Vice Chair | UNC @ Chapel Hill #Pharmacoengineering #DrugDelivery #ComplexBiologics #1stGenCollege | Executive Editor @ADDReditors

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Reposted by Juliane Nguyen
Nature Reviews Bioengineering @natrevbioeng.nature.com · 05/02/2026
The status of extracellular vesicles as drug carriers and therapeutics
dlvr.it
The status of extracellular vesicles as drug carriers and therapeutics
Nature Reviews Bioengineering, Published online: 05 February 2026; doi:10.1038/s44222-026-00405-xExtracellular vesicles (EVs) are emerging as biocompatible carriers for targeted drug delivery, yet challenges in yield, cargo loading and biodistribution persist. In this Review, key trends from over a decade of research are analysed, comparing EVs with lipid-based systems and outlining strategies for improving therapeutic translation and reporting standards.
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Juliane Nguyen @julienguyenlab.bsky.social · 06/02/2026
Excited to share our comprehensive analysis in @natrevbioeng.nature.com examining where extracellular vesicles (EVs) stand as drug carriers and therapeutics. A labor of love synthesizing preclinical, clinical, biodistribution, and nanoparticle comparison data. nature.com/articles/s44...
nature.com
The status of extracellular vesicles as drug carriers and therapeutics - Nature Reviews Bioengineering
Extracellular vesicles (EVs) are emerging as biocompatible carriers for targeted drug delivery, yet challenges in yield, cargo loading and biodistribution persist. In this Review, key trends from over...
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Reposted by Juliane Nguyen
RSC Pharmaceutics @rscpharmaceutics.rsc.org · 22/01/2026
Tuning hydrogel composition controls S. cerevisiae colony size, improving survival for oral biotherapeutics 🦠 Discover the latest research from Juliane Nguyen @julienguyenlab.bsky.social and colleagues 👇 doi.org/10.1039/D5PM...
doi.org
Effects of microparticle composition on colony morphology and viability of encapsulated therapeutic yeast for oral delivery
Engineered live biotherapeutic products (LBPs) offer a promising avenue for targeted drug delivery, particularly within the gastrointestinal (GI) tract. Among microbial chassis, Saccharomyces cerevisi...
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Reposted by Juliane Nguyen
Shirish @shrikrishnans.bsky.social · 25/07/2025
A Special Issue on Living Drug Carriers in the Journal of Controlled Release! Microbial engineers, now is your chance to show off the power of microbes for drug delivery! Submit here - www.sciencedirect.com/special-issu... Guest editors - @julienguyenlab.bsky.social, Paul Joyce, & myself
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Reposted by Juliane Nguyen
Mark Peifer (He, him) @peiferlabunc.bsky.social · 04/06/2025
@aaup.bsky.social & @unc-ch-aaup.bsky.social act for faculty. Below is the letter we sent to the UNC-CH Board of Trustees today about their shocking decision to delay action on tenure & promotion recommendations except those from the Health Affairs schools. Join us to advocate for academic freedom.
Dear UNC-CH Board of Trustees Chair Preyer and members of the Board:
We are writing as concerned members of the UNC-CH chapter of the American Association of University
Professors (AAUP). AAUP has a 100-year commitment to academic freedom. Ten days ago, faculty
learned from Faculty Chair Moracco that at your May meeting the Board of Trustees (BOT) decided not to
consider pending tenure and promotion recommendations other than those in Health Affairs schools.
Further, no personnel actions have been approved from the College of Arts and Sciences this year,
something that is highly unusual. Every continued delay threatens the very heart of our mission to “serve as
a center for research, scholarship, and creativity,” denies students’ the enriching collegiate experiences they
deserve, and erodes faculty trust in a fair and timely tenure process. We urge the BOT to reconsider its
decision and move forward now with pending tenure and promotion actions.
Promotion and tenure are central pillars of our university and universities around the nation. As you know,
each promotion and tenure decision has been carefully vetted, with external letters obtained from experts in
the faculty members field, followed by review at many levels. Faculty here are hired with an explicit
expectation that if their teaching and scholarship meet the high standards of their Department, their
College, and the Provost, they will be granted tenure.
Students at UNC-CH and people across the state expect that our flagship university will recruit the best
faculty in the nation. These actions threaten the bedrock foundations of Carolina and our status as a leading
public university. Tenure is not something unique to Carolina but is the norm at virtually every college and
university across the nation. Each time we search for a new faculty member, UNC-CH is competing with
top universities across the nation, like our peers at Duke, Berkeley, or the University of Michigan. Further,
tenured faculty members up fo…
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Reposted by Juliane Nguyen
Shirish @shrikrishnans.bsky.social · 18/05/2025
What happens when you trap probiotic bacteria inside gels? Turns out, not all bugs react the same way. We trapped gram-negative and gram-positive probiotic bacteria in gels with varying stiffnesses and saw what they did. Here's the study - tinyurl.com/Probiogel TLDR highlights in this thread 👇
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Juliane Nguyen @julienguyenlab.bsky.social · 17/05/2025
One of the absolute highlights of my job is getting to hood my PhD students at graduation. This summer, I’m thrilled to celebrate three amazing students who are finishing their PhDs. Can’t wait to see what they do next!
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Reposted by Juliane Nguyen
Nature Biotechnology @natbiotech.nature.com · 16/05/2025
A gene-editing treatment used on a 9½-month-old boy with a rare condition has the potential to help people with thousands of other uncommon genetic diseases #NBTNewsBeat www.nytimes.com/2025/05/15/h...
nytimes.com
Baby Is Healed With World’s First Personalized Gene-Editing Treatment
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Reposted by Juliane Nguyen
dpmp-unc.bsky.social @dpmp-unc.bsky.social · 14/05/2025
Special Issue in @JCRnEDITORS honors Dr. Leaf Huang—a pioneer in drug & gene delivery. Pioneering advances from liposomes to immunotherapy. doi.org/10.1016/j.jc... Kudos to @kristy-ainslie-lab.bsky.social, @julienguyenlab.bsky.social, Dr. Olivia Merkel & Dr. Yunching Chen for curating it!
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Reposted by Juliane Nguyen
American Institute for Medical & Biological Engineering (AIMBE) @aimbe-official.bsky.social · 08/05/2025
If your institution/organization is interested in joining FoNIBIB, please fill out our interest form here: aimbe.wufoo.com/forms/q1td4w... Follow @friendsofnibib.bsky.social to learn more about coalition activities and NIBIB-related updates. Researchers, your voice is more important now than ever.
aimbe.wufoo.com
Friends of NIBIB (FoNIBIB) Membership Interest
Organizations interested in joining FoNIBIB may complete the interest form below. For general information about FoNIBIB and its planned activities, please visit our website here. Please note that f...
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Reposted by Juliane Nguyen
American Institute for Medical & Biological Engineering (AIMBE) @aimbe-official.bsky.social · 08/05/2025
We are concerned about the proposed NIH budget cuts and possible consolidation of NIBIB. Related statement: friendsofnibib.org/letter-writi...) We urgently need collective advocacy for policies that support the development of NIBIB-funded life-changing medical & biological engineering technologies.
friendsofnibib.org
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Reposted by Juliane Nguyen
dpmp-unc.bsky.social @dpmp-unc.bsky.social · 18/04/2025
Honored to have @julienguyenlab.bsky.social and Brian Miller be awarded a UNC Lineberger Comprehensive Cancer Center Breast SPORE Developmental Research Program Award to help support breast cancer research. Great work!
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Reposted by Juliane Nguyen
dpmp-unc.bsky.social @dpmp-unc.bsky.social · 18/04/2025
New publication out in Digestive Diseases and Science Journal, in collaboration with @julienguyenlab.bsky.social “Engineered Probiotic Saccharomyces boulardii Reduces Colitis-Associated Colorectal Cancer Burden in Mice” rdcu.be/eibPU
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Reposted by Juliane Nguyen
dpmp-unc.bsky.social @dpmp-unc.bsky.social · 18/04/2025
Thrilled to announce that @julienguyenlab.bsky.social in collaboration with Dr. Tom Egan received an NIH R21 grant. This funding will support work on “Novel innovative ultra-elastic and instantly adhesive hydrogel patches to prevent air leak after lung surgery”
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Juliane Nguyen @julienguyenlab.bsky.social · 04/04/2025
Who would've thought you could play Bingo with posters? Introducing #PosterBingo for the Controlled Release Society Annual Meeting! Inspired by an idea #AssafZinger and his students had! See you in Philly! youtu.be/xMpxLsW-2QA?...
youtu.be
CRS 2025 Annual Meeting & Exposition: Meet Our Director of Abstract Judging, Juliane Nguyen, PhD!
YouTube video by Controlled Release Society CRS
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Reposted by Juliane Nguyen
dpmp-unc.bsky.social @dpmp-unc.bsky.social · 03/04/2025
New publication out in Digestive Diseases and Sciences in collaboration with @julienguyenlab.bsky.social “Engineered Probiotic Saccharomyces boulardii Reduces Colitis-Associated Colorectal Cancer Burden in Mice” 🔗 link.springer.com/article/10.1...
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Reposted by Juliane Nguyen
American Institute for Medical & Biological Engineering (AIMBE) @aimbe-official.bsky.social · 18/03/2025
AIMBE's new fact sheets highlighting the NIH & NSF as economic engines have dropped at lnkd.in/ePRGWqnC! Did you know that every $1 in NIH research funding yielded $2.56 in new economic activity in the U.S.? NIH-funded research also supported over 400,000 jobs across the nation in FY2024!
A fact sheet of NIH FY2024 economic impact.
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Reposted by Juliane Nguyen
American Institute for Medical & Biological Engineering (AIMBE) @aimbe-official.bsky.social · 11/03/2025
The 3/14 deadline to finalize the FY2025 budget is fast approaching! ⌛ AIMBE has developed a new advocacy letter (<1 min to send) for the scientific community to urge Congress to support our federal science agencies, including NIH, NSF, FDA, ARPA-H, CDMRP, and more 👇 takeaction.io/aimbe/suppor...
takeaction.io
Support Strong FY25 Funding for Biomedical Research by March 14
Use AIMBE's letter template below, edit as needed, or create your own message to your Members of Congress on issues that matter. Enter your contact information on the left, and your letter will be rou...
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Reposted by Juliane Nguyen
Kristy Ainslie's Lab @kristy-ainslie-lab.bsky.social · 27/02/2025
Great talk by @julienguyenlab.bsky.social at 19th International Symposium on Recent Advances in Drug Delivery Systems (RADDS) at Univ of Utah in beautiful Salt Lake City!
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Reposted by Juliane Nguyen
American Institute for Medical & Biological Engineering (AIMBE) @aimbe-official.bsky.social · 10/02/2025
AIMBE has developed a new advocacy letter on the changes to NIH indirect cost rates: aimbe.org/advocate/wri... We urge the broader biomedical research community to customize this letter (<1 minute) to contact your congressional representatives about the severe consequences of this new policy 👇
aimbe.org
Write Your Lawmakers - AIMBE
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Juliane Nguyen @julienguyenlab.bsky.social · 08/02/2025
Check out the economic impact of NIH funding in your state! www.unitedformedicalresearch.org/nih-in-your-...
unitedformedicalresearch.org
NIH In Your State - United For Medical Research
Select a state on the map to see the impact of NIH funding across America.
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Reposted by Juliane Nguyen
American Institute for Medical & Biological Engineering (AIMBE) @aimbe-official.bsky.social · 05/02/2025
Check out this publication on a pharmacy initiative co-led by some of our @aimbe-official.bsky.social Fellows, Drs. Kristy Ainslie and Juliane Nguyen! Featuring insights our own AIMBE Executive Director, Dr. Dawn Beraud (@dawnberaud.bsky.social), about the importance of advocacy 👇 #SciencePolicy
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Reposted by Juliane Nguyen
Dawn Beraud @dawnberaud.bsky.social · 05/02/2025
It was great to connect with this group. Science advocacy is more important now than ever!
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Reposted by Juliane Nguyen
Kristy Ainslie's Lab @kristy-ainslie-lab.bsky.social · 05/02/2025
@julienguyenlab.bsky.social & I organized leaders from Pharmacy Schools to discuss AI in grad ed, financial support challenges & science advocacy w/ @dawnberaud.bsky.social. Also a NextProf PharmSci program. Many of these discussions are relevant to all grad ed. Open Access: rdcu.be/d8D7A
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Reposted by Juliane Nguyen
Dawn Beraud @dawnberaud.bsky.social · 04/02/2025
Funding delays and policy changes are disrupting labs, jeopardizing jobs, and putting the future of science and biomedical engineering at risk. Trainees and early-career researchers are being hit hardest. @aimbe-official.bsky.social is taking action. Read our statement & send a letter to Congress
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Reposted by Juliane Nguyen
American Institute for Medical & Biological Engineering (AIMBE) @aimbe-official.bsky.social · 04/02/2025
AIMBE has posted a public statement on the impact of federal policy changes on biomedical research: aimbe.org/advocate/wri... Above, we have also developed an advocacy letter for members of the medical & biological engineering community to send to their congressional representatives on this matter.
aimbe.org
Write Your Lawmakers - AIMBE
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Juliane Nguyen @julienguyenlab.bsky.social · 22/01/2025
Excited to share that our work on #adhesive #auxetic #patches for dynamic organ repair has been funded by the NHLBI! These patches are highly stretchable and adaptable, making them suitable for a variety of organs, and they can deliver therapeutics while providing sustained release.
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Juliane Nguyen @julienguyenlab.bsky.social · 09/01/2025
@glassmanlab.bsky.social is leading this special issue titled "Pharmacology of Next Generation Therapeutics," which I am excited to co-edit! ASPET & the PhRMA Foundation will provide a $5,000 Challenge Award to up to five trainees for outstanding papers accepted for this JPET special collection!
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Juliane Nguyen @julienguyenlab.bsky.social · 20/12/2024
Sending Warm Holiday Wishes from Our Lab to Yours!
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Juliane Nguyen @julienguyenlab.bsky.social · 16/12/2024
Congrats to my PhD student Omar Budayr on his 1st author review titled: Harnessing extracellular vesicle-mediated crosstalk between T cells and cancer cells for therapeutic applications Use this link for 50 days of free access to the article: authors.elsevier.com/a/1kHALcI2-5...
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Juliane Nguyen @julienguyenlab.bsky.social · 12/12/2024
Congratulations to Nguyen Lab's PhD student for being awarded the @PhRMAfoundation Predoctoral Fellowship in Drug Delivery! This recognition is truly well deserved. Way to go, Ameya! www.phrmafoundation.org/news-events/...
phrmafoundation.org
PhRMA Foundation Awards $2.5M in 2025 Drug Discovery, Delivery, and Translational Medicine Fellowships and Grants
The PhRMA Foundation provided 2025 awards to 34 early-career scientists focused on drug discovery, drug delivery, and translational medicine research.
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Reposted by Juliane Nguyen
dpmp-unc.bsky.social @dpmp-unc.bsky.social · 19/11/2024
Grad applications, including letters, must be received by December 3rd! Learn more here: youtu.be/hYwKWXHWYuQ?...
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