Communication between distant brain regions is mediated by plastic networks of gap junction-coupled astrocytes.

Nature Machine Intelligence - LLM use in scholarly writing poses a provenance problem

Post-traumatic stress disorder is a mental disorder that may occur in the aftermath of severe psychological trauma. Epigenetic changes in the brain may play a critical role in understanding the neurob...

While histamine-1-receptor (H1R) signaling in neurons regulates arousal, these receptors are also abundant on cortical astrocytes. This study shows that astrocytic H1R signaling modulates calcium acti...

A multi-cell-type drug discovery strategy targeting dysregulated gene networks in neurons and glia identified letrozole and irinotecan as a combination therapy that significantly improved memory and r...

A comprehensive analysis of the cell-specific molecular regulatory mechanisms underlying post-traumatic stress disorder in the human prefrontal cortex.

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Nature Neuroscience - Using the AstroLight system, the authors reveal that astrocytic ensembles in the nucleus accumbens regulate cue-motivated reward behavior, demonstrating that selective...

The 5xFAD transgenic model, popular in Alzheimer’s disease research, exhibits varying cerebral plaque burden depending on the parental source of the transgene. Mice inheriting the transgene paternally...