Qingyu Chen, PhD, and his team set out to study how artificial intelligence (AI) language models are adapted for medicine and found that what these models

This study strengthens the indication that tobacco smoking elicits sex-specific patterns of striatal dopamine release that align with behavior. Men showed

SNMMI is pleased to announce our annual list of early career professionals selected as “Ones to Watch” in 2026.

A study using positron emission tomography (PET) imaging has found that patients with schizophrenia had significantly lower muscarinic acetylcholine M1 receptor availability (about 13%–19%) across multiple brain regions than healthy individuals.

Anahita Bassir Nia, MD, assistant professor of psychisatry, has received an R01 award from the National Institute on Drug Abuse to investigate cannabinoid

Neuropsychopharmacology - Reversible alterations of brain acetate metabolism associated with alcohol consumption

Four Department of Radiology and Biomedical Imaging faculty were honored at the Yale Diagnostic Radiology Faculty Mentoring Awards ceremony on June 24.

There is growing interest in the contributions of brain muscarinic M1 receptors to the neurobiology of schizophrenia (SZ). Postmortem evidence strongly indicates M1 deficits in SZ patients. Recently,…

Richard E. Carson, PhD, has been named the 2026 recipient of the prestigious Paul C. Aebersold Award. Carson is professor of Biomedical Engineering and of Radiology and Biomedical Imaging at Yale Univ...

This Perspective promotes the use of external validation using independent datasets for human neuroimaging studies.

Nature Human Behaviour, Published online: 15 April 2026; doi:10.1038/s41562-026-02447-yAcross more than 12,000 MRI scans, the authors show that features discarded during feature selection can rival top-ranked ones in predicting behaviour yet imply different brain circuits, warning that focusing only on top features can mislead neurobiology.

Variance reduction with synaptic density imaging in Parkinson’s disease using direct-4D PET image reconstruction, Gravel, Paul, Gallezot, Jean-Dominique, Fontaine, Kathryn, Matuskey, David, Carson, Richard E

Eight Yale School of Medicine faculty members are among the leading experts in science, technology, engineering, mathematics, and medicine newly elected to the

Neuropsychopharmacology - In vivo evidence for metabotropic glutamate receptor 5 dysregulation in chronic pain

ObjectiveTo determine if combining PET-derived beta-cell mass (BCM) estimates with MRI-based morphology metrics improves the prediction of beta-cell function...

Dysregulation of the neuroimmune system is increasingly recognized as a key contributor to psychiatric illness, yet its complexity and the limitations of current methodologies have hindered a clear…

On November 10, 2025, Dr. Pamela Kunz hosted a Smilow Shares in honor of NETS Awareness Day.

The third Nonlinear Parameter Parley (NLPP 3.0) was held on May 30, 2025, at Seoul National University Hospital. Organized by Dr. Su Jin Kim, Prof. Evan Morris,

Caricature artists exaggerate distinctive features of an individual, deepening a cleft chin or multiplying freckles. Yale researchers have now applied a similar approach to maps of neural connections, emphasizing individual differences to see if they yield useful information.

Background 18F-FE-PE2I is a highly selective dopamine transporter (DAT) positron emission tomography (PET) radioligand, whereas 11C-UCB-J targets synaptic vesicle glycoprotein 2A (SV2A), enabling th...

Image-derived input functions are noninvasive alternatives to arterial blood sampling for PET kinetic modeling, allowing one to measure the whole-blood time–activity curve (BTAC). However, partial-vol...

Neural variability, or variation in brain signals, facilitates dynamic brain responses to ongoing demands. This flexibility is important during develo…

A new PET tracer can provide insights into how spinal cord injuries affect not only the spinal cord, but also the brain, according to new research published in The Journal of Nuclear Medicine

The Yale Biomedical Imaging Institute will drive transformative advancements in both basic science and clinical translation.