Mechanical forces shape the developing heart by controlling cell volume through a Piezo1-driven hydraulic mechanism.

The developing heart integrates several progenitor cell types. Here they show that the pericardium enveloping the heart develops among cells that form the mesothelium around inner organs and body cavities, distinct from the classic heart field.

The left/right position of ventricles needs to be maintained after heart looping, an unexpected step affected in heterotaxy.

Epithelial tissues line the surfaces of vital organs and are often densely packed in a disordered, mechanically arrested state, referred to as jammed or glassy state. While collective migration at low...

Many organisms self-organize crystals for vision, pigmentation, or storage. In zebrafish, iridophores produce anisotropic crystals in iridosomes. Using imaging and genetic tools, crystal growth is sh...

Karolinska Institutet is a world-leading medical university with a long and proud history of ground-breaking research. We are now recruiting outstanding early-career researchers with particularly exce...

The principal theme of the EMBO Workshop is the Molecular and Developmental Biology of Drosophila. Supported by EMBO over four decades, this will be the 24th biennial “Crete meeting”. With the a…

Behind the Paper Story of “Combined forces of hydrostatic pressure and actin polymerisation drive endothelial tip cell migration and sprouting angiogenesis”.

Nature Communications - Here the authors show that Plasmodium falciparum egress products disrupt endothelial barrier and activate JAK-STAT and interferon type response in a 3D blood-brain barrier...

Andrews et al. demonstrate that multiscale feedback between mechanical and chemical cues builds a functional heart to support zebrafish embryonic life. Cell recruitment and organ-scale forces drive tr...

BACKGROUND Single ventricle congenital heart disease (SV-CHD) is a uniformly lethal condition. Survival depends upon the Glenn surgery, which shunts venous blood directly to the pulmonary arteries wit...

The primary cilium dynamically assembles and disassembles while maintaining structural stability and tightly regulated length, but the mechanisms that control this remain unclear. This study shows tha...

Are you ready to lead groundbreaking research in Genome Biology? Join us at EMBL! We are seeking a motivated scientist to lead an independent research group addressing exciting and original biological...

Boraas et al. identify that mRNAs and the stress granule RNA-binding protein G3BP1 form ribonucleoprotein (RNP) complexes at FAs. These RNPs regulate FA protein mobility and cell migration under norma...

Super-resolution technique works with off-the-shelf optical microscopes.

Job no: R-0000002388 Position Title: Assistant Professor of Neuroscience and Behavior Work Type: Faculty Full time In-Person Start Date: 07/01/2026 Job Description: The Department of Neuroscience and ...