Microtubules are essential components of the cytoskeleton, yet important links between their molecular properties and organismal functions remain unresolved. In this Roadmap, Janke et al. discuss key ...

Mitochondrial research and genome maintenance at Ludwig-Maximilians-University.

HAK-actin is a new probe that may help researchers see the actin cytoskeleton in sharper detail using expansion microscopy.

Centrosome stability is essential for spindle bipolarity. Schreiner et al. show that CDK-1 primes PCMD-1 for PLK-1 phosphorylation. Mutations in PLK-1 dock

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Understanding the evolution of the bilaterian brain requires a detailed exploration of the precise nature of cellular and subcellular differences between related species. We undertook an electron micr...

Caenorhabditis elegans is a genetically tractable organism that has become one of the leading in vivo models for cilia research. Cilia are not require…

The authors show that anillin mediates unilateral cytokinesis by blocking the effector binding site of active RhoA. The interaction between active RhoA and

Curtailment of freedoms and disregard for the rule of law in the United States is destroying the ability of science to serve the nation’s, and the world’s, interests. Researchers can take action.

In mammals, cohesin and CTCF organize the 3D genome into topologically associating domains (TADs) to regulate communication between <i>cis</i>-regulatory elements. Many organisms, including <i>S. cere...