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Inna Nechipurenko

@inechipurenko.bsky.social
361 followers 345 following 5 posts

Neurobiologist intrigued by cilia. Asst. Prof at Worcester Polytechnic Institute.

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Reposted by Inna Nechipurenko
Javier Apfeld @javierapfeld.bsky.social · 05/08/2026
We need your help spreading the word about the C. elegans Community Mentor Match Program! Please talk about the program in your next lab meeting and share this slide with your lab: docs.google.com/presentation...
docs.google.com
Mentor match QR codes 2026
Join the C. elegans Community Mentor Match Program! sign up for mentors sign up for mentees and to join peer-mentoring groups https://forms.gle/nfNWQRnpymu6tCYC9 https://forms.gle/pZdwor7wERmQ4oMG8
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Reposted by Inna Nechipurenko
Piali Sengupta @senguptalab.bsky.social · 01/04/2026
Another paper from our awesome lab out today @nature.com. Led by 🌟 PD Jihye Yeon with fantastic collaborators. We show how an ionotropic receptor (related to insect sensory IRs) in a single pharyngeal enteric neuron senses ingested salts and protects the worm from high salt stress. rdcu.be/fbd4a
rdcu.be
An enteric neuron ionotropic receptor regulates salt stress resistance
Nature - The I3 pharyngeal enteric neuron in Caenorhabditis elegans detects high-salt conditions, and the GLR-9 ionotropic salt receptor expressed specifically in I3 regulates genes related to salt...
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Reposted by Inna Nechipurenko
Piali Sengupta @senguptalab.bsky.social · 28/01/2026
Our first 2026 paper is out @currentbiology.bsky.social! 👏 to @nathancsharris.bsky.social (now Asst Prof, GA State) and PD Priya Dutta. Here we show how transcriptional and trafficking pathways coordinate thermoreceptor levels to precisely modulate response plasticity www.cell.com/current-biol...
cell.com
Experience-dependent reconfiguration of thermoreceptors regulates neuronal response plasticity
Harris, Dutta, et al. find that experience-dependent plasticity in the activation threshold of the AFD thermosensory neurons is mediated by modulating warm and cold thermoreceptor levels at the sensor...
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Reposted by Inna Nechipurenko
Javier Apfeld @javierapfeld.bsky.social · 28/01/2026
Friends! I am so happy to share our new preprint! Hydrogen peroxide has been the most common reactive chemical threat to life forms since the Great Oxygenation Event 2.5 billion years ago. How do animals like C. elegans sense it fast and escape? www.biorxiv.org/content/10.6... Thread 1/
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Reposted by Inna Nechipurenko
Genetics Society of America @genetics-gsa.bsky.social · 31/12/2025
In #GENETICS, @inechipurenko.bsky.social and colleagues studied the effects of mutations in the GNAI1, a G protein–coupled receptor gene, identifying their effects on ciliogenesis in human cells and #Celegans. buff.ly/MF1bSVn
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Reposted by Inna Nechipurenko
Piali Sengupta @senguptalab.bsky.social · 15/08/2025
More new science from the lab! Led by @nathancsharris.bsky.social (now at GA State) and PD Priya Dutta. We describe how experience tunes the ratios of functional receptors in a single sensory neuron via coordinating transcriptional and post-transcriptional mechanisms to drive response plasticity.
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Reposted by Inna Nechipurenko
Javier Apfeld @javierapfeld.bsky.social · 10/01/2025
Worm people: Were you a mentor, mentee, or in a peer-mentoring group in the C. elegans Mentor Match program last year? We need your feedback! Please fill out this quick survey to help us evaluate the program and improve it for the coming year. forms.gle/KKDtZwFdEzjP...
forms.gle
C. elegans Community Mentor Match 2024 feedback survey
Thank you for providing feedback about your experiences as a mentee, mentor, and peer group member in this year's C. elegans Community Mentor Match program! Please skip questions that are not relevan...
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Reposted by Inna Nechipurenko
Carolyn Bertozzi @carolynbertozzi.bskyverified.social · 05/12/2024
Amazing new work from the lab of @aliceyting.bsky.social @stanfordmedicine.bsky.social @stanfordbiosci.bsky.social, engineered GPCRs for ligand-activated cell responses www.nature.com/articles/s41...
nature.com
Synthetic GPCRs for programmable sensing and control of cell behaviour - Nature
Modular synthetic G-protein-coupled receptors with nanobody-based ligand-recognition domains can be designed and used to programme transgene expression, real-time fluorescence or endogenous G-protein ...
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Reposted by Inna Nechipurenko
Piali Sengupta @senguptalab.bsky.social · 26/11/2024
🧪 Lab's latest!! Work by PD (and now PI) Alison Philbrook. C. elegans sensory neurons have gorgeous #cilia. We’ve always thought that a) no cilia = no sensory responses, & b) no IFT = no cilia. Punchline is we thought wrong. Read paper for more! #neuroscience journals.plos.org/plosbiology/...
journals.plos.org
Cilia structure and intraflagellar transport differentially regulate sensory response dynamics within and between C. elegans chemosensory neurons
The relative contributions of intraflagellar transport (IFT) and cilia structure to sensory neuron responses remains unclear. This study reveals unexpected complexity in the contribution of IFT and ci...
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Reposted by Inna Nechipurenko
Javier Apfeld @javierapfeld.bsky.social · 11/10/2024
Hey bluesky friends! We are hiring a tenure-track faculty with a focus on human-plant interactions 🌱 Get this: we want graduating PhDs and early postdocs to apply! 🤯 We really want candidates that'll advance diversity, equity, and inclusion. I am in the search committee. Contact me if interested!
northeastern.wd1.myworkdayjobs.com
Assistant Professor - INVEST Program, College of Science
About the Opportunity About the Opportunity: The College of Science at Northeastern University invite applications for positions at the rank of Assistant Professor beginning in academic year 2025-2026...
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Reposted by Inna Nechipurenko
Piali Sengupta @senguptalab.bsky.social · 18/12/2023
All #Celegans peeps! Drawing your attention to this really amazing tour-de-force from Changchun Chen's lab (with a small contribution from us). An incredible resource of strains with combos of 1654 GPCRs KO'd. Deals with the issue of gene duplication and redundancy. www.nature.com/articles/s41...
nature.com
Dissecting the genetic landscape of GPCR signaling through phenotypic profiling in C. elegans - Natu...
To overcome challenges posted by vast number of GPCR genes and redundancy, the authors disrupted nearly all GPCR-encoding genes in C. elegans, enabling effective examination of GPCR signaling and offe...
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Reposted by Inna Nechipurenko
Piali Sengupta @senguptalab.bsky.social · 01/11/2023
Another spectacular paper about cilia and their structural and positional diversity in the brain. Wonder why oligodendrocytes and microglia don't have 'em but astrocytes do. From Carolyn Ott at Janelia 🧪 🧠🟦 www.biorxiv.org/content/10.1...
biorxiv.org
Nanometer-scale views of visual cortex reveal anatomical features of primary cilia poised to detect ...
bioRxiv - the preprint server for biology, operated by Cold Spring Harbor Laboratory, a research and educational institution
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Reposted by Inna Nechipurenko
Javier Apfeld @javierapfeld.bsky.social · 18/10/2023
Aging folks, my university is hiring! We really want candidates that'll advance diversity, equity, and inclusion. Please share widely and feel free to ask me any questions!
northeastern.wd1.myworkdayjobs.com
Open Rank: Assistant Professor/Associate Professor/Professor - Healthy Aging and Regeneration, Biolo...
About the Opportunity About the Opportunity: The College of Science at Northeastern University invites applications for full-time faculty positions at all ranks (Assistant Professor, Associate Profess...
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Reposted by Inna Nechipurenko
Maureen Barr @barrlab.bsky.social · 29/09/2023
Abstract submission for #TAGC24 is open now through Nov 9! Topics include Neurogenetics, Genomes & Genomics, Ecological Genetics, plus model organism meetings, amazing keynotes, industry sessions, career/networking events & much more. genetics-gsa.org/tagc-2024/ab...
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Reposted by Inna Nechipurenko
Richard Sever @richardsever.bsky.social · 28/09/2023
bioRxiv goes big on Bluesky: accounts for all subject categories now available (Please Reskeet) connect.biorxiv.org/news/2023/09...
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Reposted by Inna Nechipurenko
Piali Sengupta @senguptalab.bsky.social · 15/09/2023
Two groundbreaking women neuroscientists. Eve has been an incredible mentor and friend and support system over my time at Brandeis. Congrats to Eve and Lily! www.rockefeller.edu/news/34584-l...
rockefeller.edu
Lily Jan and Eve Marder to receive 2023 Pearl Meister Greengard Prize - News
Groundbreaking neuroscientists Lily Jan and Eve Marder will jointly receive the 2023 Pearl Meister Greengard Prize, an award which recognizes outstanding women scientists. The award will be presented ...
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