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sevinc

@ercanlab.bsky.social
823 followers 972 following 5 posts

professor of biology @nyu, genome organization, gene regulation, chromosomes in general and X in particular, SMCs, c. elegans, evolution

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NY Times Pitchbot @nytpitchbot.bsky.social · 09/09/2026
Yes, the Republican party will likely destroy our country if they maintain control of Congress. But I still refuse to vote for any Democrat whose views differ in any way from mine on any issue.
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Abby Dernburg @adernburg.bsky.social · 07/09/2026
Biomedical scientists - a reminder that NIH proposes to "improve" peer review by hiding impact scores from Program Officers and applicants, and binning applications into broad categories of "Most competitive,""Competitive," or "Not discussed." Please provide feedback before the October 13 deadline!
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Ran Blekhman @blekhman.bsky.social · 27/06/2026
I wanted to like QED's new 1% preprint ranking. I really did. But the more I looked at the data, the more uncomfortable it made me. Here is my full peer review. open.substack.com/pub/blekhman...
open.substack.com
My Peer Review of The 1%
I wanted to like QED's new 1% ranking. I don't.
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Elphege Nora Lab at UCSF @elphegenoralab.bsky.social · 13/05/2026
Why can't we explain enhancer action despite 2 decades of chromosome conformation technologies? 😬 Our new study spearheaded by Leonid Mirny's group points to a flaw in our assumptions, and to a solution from physical principles By @timothyfoldes.bsky.social 💻& @karissalhansen.bsky.social 🧪 🧵👇
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Damian Dalle Nogare @damiandn.bsky.social · 02/05/2026
"I flunked the easiest and most obvious moral test of the last 50 years" isn't exactly the flex you think it is.
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Mayor Zohran Kwame Mamdani @mayor.nyc.gov · 15/04/2026
Happy Tax Day, New York. We’re taxing the rich.
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Mayor Zohran Kwame Mamdani @mayor.nyc.gov · 15/04/2026
We will be taxing the ultra-wealthy and global elites.
nytimes.com
Hochul Proposes Tax on N.Y.C. Second Homes That Are Worth $5 Million
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Brad Lander @bradlander.bsky.social · 10/12/2025
Pitch in to join the fight: secure.actblue.com/donate/lande...
secure.actblue.com
Donate to Brad Lander
Show your support with a contribution.
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Brad Lander @bradlander.bsky.social · 10/12/2025
I’m running for Congress because we need leaders who will fight, not fold. I recognize this moment, and I’m ready to meet it. #FightDontFold #LanderForNYC #LanderForCongress
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Ran Blekhman @blekhman.bsky.social · 19/11/2025
I wrote about the recent autism-microbiome paper, why I think it's the most important microbiome paper this year, and what it says about the field open.substack.com/pub/blekhman...
open.substack.com
The Autism-Microbiome Hypothesis Is Falling Apart
Why this new review paper should be required reading for every microbiome researcher
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Zeitlinger Lab @zeitlingerlab.bsky.social · 19/11/2025
We are pleased to announce a new preprint by @mlweilert.bsky.social: “Widespread low-affinity motifs enhance chromatin accessibility and regulatory potential in mESCs” (www.biorxiv.org/content/10.1...). See summary and longer recap below: (TLDR; low-affinity motifs matter as pioneers!)
biorxiv.org
Widespread low-affinity motifs enhance chromatin accessibility and regulatory potential in mESCs
Low-affinity transcription factor (TF) motifs are an important element of the cis-regulatory code, yet they are notoriously difficult to map and mechanistically incompletely understood, limiting our a...
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Needhi Bhalla 💅🏽 @needhibhalla.bsky.social · 30/10/2025
🧪hey all, a friend and colleague, @maddoxfornc.bsky.social, is running for Congress in North Carolina. He is a scientist, professor, and parent, perspectives that are especially important right now. I hope you will support his run for Congress. Find out more here: www.maddoxforcongress.com/about/
maddoxforcongress.com
Meet Paul Maddox
Paul Maddox is a world-renowned cancer researcher, two-time entrepreneur, and native son of Western North Carolina–and now, a candidate for U.S. Congress. ....
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Richard Sever @richardsever.bsky.social · 27/10/2025
Nature Communications will publish ~10K papers in 2025 pubmed.ncbi.nlm.nih.gov?term=%22Natu... That's ~$70M in revenue, while many of the non-profit journals that used to occupy that slot in the journal hierarchy have seen a precipitous decline in submissions in the 15 years it's existed.
pubmed.ncbi.nlm.nih.gov
[Invalid form] - Search Results - PubMed
[Invalid form] - Search Results - PubMed
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samuel mehr @mehr.nz · 26/10/2025
I'm floored by colleagues who are totally not interested in understanding the Nature Comms scourge of academic publishing and just throw their science and their money at these losers
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sevinc @ercanlab.bsky.social · 10/10/2025
C. elegans is a little animal with sexually dimorphic tails. Fitch lab does wonderful work on the evolution and transcriptional regulation of tail tip morphogenesis in nematodes.
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Genetics Society of America @genetics-gsa.bsky.social · 09/10/2025
New in #GENETICS: Using Chip-seq and mutant analysis, Fernandez et al. show the transcriptional control of the male tail tip morphogenesis during development by the master regulator of a male-specific morphogenesis gene DMD-3. buff.ly/EGahYv2
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Julien Richard Albert @jrichardalbert.bsky.social · 03/10/2025
I didn't think I could admire Azim Surani more than I already did journals.biologists.com/dev/article/...
journals.biologists.com
An interview with Azim Surani
Professor Azim Surani is the Director of Epigenomics and Germline Imprinting at the Gurdon Institute in Cambridge, UK. He is this year's recipient of both the prestigious Kyoto Prize and the Paul Ehrl...
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Celja Uebel @celjauebel.bsky.social · 01/10/2025
Hi fellow C. elegans scientists, I've made a few videos that may be of use for new trainees working in worm labs. Hoping to add more in the future, but figured I'd share this resource as is in case it's helpful :) www.youtube.com/@Workingwith...
youtube.com
Working with C. elegans
This channel provides clear demonstrations of core C. elegans lab skills, including: recognizing life stages and common phenotypes, picking and manipulating worms, and maintaining healthy cultures. De...
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Robert Haase @haesleinhuepf.bsky.social · 01/10/2025
For academic purposes, I generated 100 UMAPs from the same tabular raw data, I sorted them and the result looks too funny to not share it with you 😃 haesleinhuepf.github.io/BioImageAnal...
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Matt Rockman @wormsrock.bsky.social · 24/09/2025
C. elegans is a real animal and we set out to understand how it comes to have its distinctive biogeography. Its ancestral center of diversity is in the higher elevation forests of Hawaii. Its closest relatives are spread across east Asia. Did they travel from Asia? [Preprint 🧵]
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Jeremy Berg @jeremymberg.bsky.social · 31/07/2025
This is my reminder of what the American people need from her. 2/2
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Abby Dernburg @adernburg.bsky.social · 31/07/2025
For who still thinks this can’t happen here… it’s already happening. www.theatlantic.com/science/arch...
theatlantic.com
Every Scientific Empire Comes to an End
America’s run as the premiere techno-superpower may be over.
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Mark A. Hanson @hansonmark.bsky.social · 10/07/2025
The "reproducibility crisis" in science constantly makes headlines. Repro efforts are often limited. What if you could assess reproducibility of an entire field? That's what @brunolemaitre.bsky.social et al. have done. Fly immunity is highly replicable & offers lessons for #metascience A 🧵 1/n
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Ryan Grim @ryangrim.bsky.social · 28/06/2025
Andrew Cuomo thinks its absurd for the city try to to own a grocery story while New York State owns three (!) ski resorts and Cuomo personally oversaw their operation, even heralding it in his state of the state address. Look it up if you don’t believe me.
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Bonnie Honig @bonniehonig.bsky.social · 20/06/2025
Great ad. This guy is great. Don’t let anyone tell you otherwise. Don’t be deterred by racist scare tactics! This guy is great, as is Lander. Don’t rank Cuomo.
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Paolo Crosetto @paolocrosetto.bsky.social · 15/06/2025
Springer-Nature launched a series of "Discover" journals that closely mimic MDPI titles -- sharing *identical* journal names, and likely similar business model. What is going on, and why researcher will - as always - fall for it? A 🧵 the-strain-on-scientific-publishing.github.io/website/post...
the-strain-on-scientific-publishing.github.io
Springer Nature Discovers MDPI – The Strain on Scientific Publishing
Home page for the paper ‘The Strain on Scientific Publishing’ by Mark A Hanson, Dan Brockington, Paolo Crosetto and Pablo Gomez Barreiro
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Mark A. Hanson @hansonmark.bsky.social · 10/06/2025
New from The Strain Team: 🎊 Springer Nature Discovers MDPI 🎊 Springer Nature has spawned a copycat journal series called "Discover" mimicking #MDPI journal titles and citation behaviours. We even made a browser game to prove it (see 🔗). Gross! 😀 1/n #ResearchIntegrity #SciPub #AcademicSky
the-strain-on-scientific-publishing.github.io
Spinger Nature Discovers MDPI – The Strain on Scientific Publishing
Home page for the paper ‘The Strain on Scientific Publishing’ by Mark A Hanson, Dan Brockington, Paolo Crosetto and Pablo Gomez Barreiro
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John Dennehy @drjdennehy.bsky.social · 28/05/2025
CUNY and SUNY faculty, please sign this letter to the NY State Congressional Delegation protesting cuts to research funding (and all the other crap going on)! docs.google.com/forms/d/e/1F... Thank you for reposting!
docs.google.com
New York's Congressional Delegation Must Defend Federal Research Funding for CUNY & SUNY. List of signatories.
FACULTY & STAFF: ADD YOUR NAME BELOW TO THIS OPEN LETTER WRITTEN BY THE DEFENDING RESEARCH FUNDING WORKING GROUP OF THE PROFESSIONAL STAFF CONGRESS/CUNY Federal investment in scientific research gene...
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Hell Gate *subscribe today!* @hellgatenyc.com · 16/05/2025
At last night's mayoral forum cosponsored by Hell Gate and NY Focus at the Public Theater, @zohrankmamdani.bsky.social asked @bradlander.bsky.social a question that Lander was more than ready to answer: What he thought was the worst thing Andrew Cuomo did as governor.
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Hank Green @hankgreen.bsky.social · 17/05/2025
The new Neil Halloran documentary on Smallpox has completely changed how I see the RFK Jr. version of the world. Neil (softly) argues that realizing that disease isn't the fault of the sick /or/ the fault of the Gods ushered in a new future where we felt the authority to care for each other.
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Hank Green @hankgreen.bsky.social · 17/05/2025
What a horror show to have put that man in charge of anything. The documentary is very short and very good. You can watch it here: www.youtube.com/watch?v=ybVZ...
youtube.com
Defeating a Virus That Killed Half a Billion People – The Plea
YouTube video by Neil Halloran
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sevinc @ercanlab.bsky.social · 07/05/2025
our latest work summary: cohesin is preferentially loaded at/near active enhancers and loop extrudes in both directions, forming loops that create the dna contacts that appear as the newly defined "fountains" in hic maps pubmed.ncbi.nlm.nih.gov/40210441/
pubmed.ncbi.nlm.nih.gov
Cohesin organizes 3D DNA contacts surrounding active enhancers in C. elegans - PubMed
In mammals, cohesin and CTCF organize the 3D genome into topologically associating domains (TADs) to regulate communication between <i>cis</i>-regulatory elements. Many organisms, including <i>S. cere...
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NPR @npr.org · 01/05/2025
Politicians, lawyers and journalists who left behind autocratic systems in Europe, Asia and Latin America see the Trump administration employing similar methods.
npr.org
People who fled authoritarian regimes say Trump's tactics remind them of home
Politicians, lawyers and journalists who left behind autocratic systems in Europe, Asia and Latin America see the Trump administration employing similar methods.
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Javier Apfeld @javierapfeld.bsky.social · 29/04/2025
Love worms, molecular genetics, and big questions? We’re hiring a postdoc to build a CRISPRa toolkit to identify new aging mechanisms in C. elegans. Email or DM me to find out more. Please share & repost!
northeastern.wd1.myworkdayjobs.com
Postdoctoral Research Associate, Biology
About the Opportunity Job Summary The Apfeld Lab at Northeastern University is seeking a postdoctoral researcher to investigate how genes work together to determine the maximum lifespan of the nematod...
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Whitney Gibbs @whitgibbs.bsky.social · 30/04/2025
My lab at NYU is hiring a postdoc interested in RNA biology and local translation in neurons following axonal injury/neurodegenerative diseases!! Apply here: apply.interfolio.com/165681
apply.interfolio.com
Apply - Interfolio {{$ctrl.$state.data.pageTitle}} - Apply - Interfolio
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Mark Peifer (He, him) @peiferlabunc.bsky.social · 28/03/2025
The DNA in our cells is not naked but instead is compacted by being wrapped around nucleosomes assembled from histone proteins. In our current view, this produces the chromatin architecture that leaves some regions open for transcription while others are more compacted & transcriptionally silent 1/n
Diagram of chromatin and nucleosomes
from  https://www.genome.gov/genetics-glossary/Nucleosome
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Sherrilyn Ifill @sifill.bsky.social · 21/03/2025
Again, pay attention to how it goes.
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Jeremy Berg @jeremymberg.bsky.social · 09/03/2025
Bluetorial: Women, courage, and leadership What follows will include some generalizations based on population averages of what I have experienced over the course of my career. There are, of course, exceptions in every group who are substantially more to one extreme or the other.
media.tenor.com
a cartoon says hey everybody an old man 's talking while bart simpson looks on
ALT: a cartoon says hey everybody an old man 's talking while bart simpson looks on
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Matt Rockman @wormsrock.bsky.social · 07/03/2025
Lots of people at the rally in New York! Josh Dubnau from Stony Brook gave the speech the moment demands: attacks on science funding are bad, but they’re downstream of fascism, and we need to fight the fascism even when we’re not the targets
100s of people at the Stand up for Science rally in Washington Square Park. They’re holding signs in front of the Wash Square arch
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Jeremy Berg @jeremymberg.bsky.social · 06/03/2025
A well-done story from a reporter in Türkiye. trt.global/world/articl... Thanks 1/3
trt.global
TRT Global - Cuts in US research funding could cede scientific lead to China, say scientists
Slashing of federal funds and mass layoffs announced by Trump administration could cripple research at universities and labs, risking a shift in scientific leadership to competitors like China, scient...
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Julia Willett @jlewillett.bsky.social · 01/03/2025
"downsizes" is a weak way of saying "forced to cancel dozens of programs, which jeopardizes future STEM careers of talented undergrads" @science.org www.science.org/content/arti...
science.org
NSF downsizes summer research program for undergraduates
Many participants are from groups underrepresented in science
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Michael Harriot @michaelharriot.bsky.social · 22/02/2025
By accepting Trump’s anti-Black premise and regurgitating the narrative that equates anything Black as DEI, the NY Times has become part of the propaganda machine
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Drug Monkey @drugmonkey.bsky.social · 22/02/2025
It’s probably a good day to explain to your non-scientist socials that graduate students are not merely the next generation of academic science, they are an important component of the current scientific labor force. Feel free to mention that this is cut rate labor as well.
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Abby Dernburg @adernburg.bsky.social · 21/02/2025
I hope that everyone in the private sector who depends on federal grants to train their researchers and staff, pay for their services and products, or benefits in any other way from federal funding will come out to #standupforscience!
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Gul Dukat @realguldukat.bsky.social · 20/02/2025
ATTENTION BAJORAN WORKERS #STARTREK #SISKO197
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Jen Jennings @jenjennings.bsky.social · 21/02/2025
DEI initiatives are still legal. Universities need to stand their ground. A Friday gift to your university's General Counsel Office - courtesy of an all star lineup of civil rights lawyers and scholars. You're going to want to read this.
app.box.com
OGC Memo re Trump DEI and SFFA 2025 02 20.pdf | Powered by Box
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Abby Dernburg @adernburg.bsky.social · 20/02/2025
To all people who value science as a source of truth, cures for diseases, and hope for our climate and future, here are 2 hard truths: 1) our current research ecosystem is already strained and very fragile; 2) If it gets broken it will take a generation or longer to repair. Here’s why: 1/n
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Marian Walhout @marianwalhout.bsky.social · 20/02/2025
A must read for any (systems) biologist! www.cell.com/cell-systems...
cell.com
Should biology put complexity first?
The dictum “Everything should be made as simple as possible, but no simpler” poses a problem for biology. How simply can it be told without doing damage to its complex nature? The answer might be foun...
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Meredith Wadman @meredithwadman.bsky.social · 14/02/2025
@altcdc.bsky.social if you are a CDC probationary employee who is losing your job today you can reach me on Signal. meredithwadman.13 Please help @science.org tell this story. Confidentiality guaranteed.
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