Reposted by Kinga Kamieniarz-Gdula
Kinga Kamieniarz-Gdula
@stoplab.bsky.social
1.7K followers 1.1K following 106 posts
Molecular biologists fascinated by gene ends. PI at IBMiB and CAT, Adam Mickiewicz University in Poznan, Poland. Oxford University and @mpi_ie Freiburg alumna. STOPlab.org
![Structure and chemistry of G-quadruplexes (G4s). Structure of a duplex-G4-duplex DNA molecule (image from the RCSB PDB (http://www.rcsb.org/) of PDB ID 8DUT [4]). Duplex DNA is depicted in purple and dark green; G4 DNA is depicted in yellow, and both side and top views of the G4 structure are shown. The displaced strand opposite the G4 has been omitted for clarity. A. Chemistry of Watson-Crick hydrogen bonds between complementary cytosine and guanine on duplex B-DNA. B. Chemistry of planar Hoogsteen hydrogen bonds between four guanines within a G-tetrad. Guanines in a tetrad are usually coordinated by a monovalent cation such as potassium (K+). Created in BioRender; credit to Gallina, I. (2026)](https://cdn.bsky.app/img/feed_thumbnail/plain/did:plc:5522ztebtekoor5efelihqhb/bafkreie6zo3dm7joyzvvh4vbf6w64sackwg3zul7442yh2mvb5mpodsvoa)
