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IMBB AMU Poznań

@uam-ibmib.bsky.social
194 followers 814 following 65 posts

Institute of Molecular Biology & Biotechnology, Faculty of Biology at the Adam Mickiewicz Univeristy in Poznan @UAM_Poznan 🇵🇱 🇪🇺 website: t.co/fQOshWexcu

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IMBB AMU Poznań @uam-ibmib.bsky.social · 28/09/2026
Join us today for our Institute Seminar at IMBB! 🤩 📢 "Identification and engineering of biochemical pathways in medicinally important plants" 👤 Prof. Kashmir Singh (Panjab University, India) 📅 September 28, 2026 | 🕘 12:00 PM 📍 Mala Aula (Faculty of Biology, AMU)
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IMBB AMU Poznań @uam-ibmib.bsky.social · 17/09/2026
That's a wrap on PMM 2026 in Poznań! 🌿🧬 Three fantastic days with 90+ plant meiosis researchers from 12 countries. Special thanks to Keynote Neil Hunter (UC Davis) and lead organizer Maja Szymańska-Lejman! 👏 Congrats to Nicola Gorringe (Best Talk 🏆) & Youngkyung Lee (Best Poster 🥇).
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IMBB AMU Poznań @uam-ibmib.bsky.social · 14/09/2026
Join us for our Institute Seminar at IMBB! 🤩 📢 "Iron-sulfur clusters: An essential protein cofactor with complex biosynthesis and disease relevance" 👤 Prof. Roland Lill (Marburg University, Germany) 📅 September 17, 2026 | 🕘 3:00 PM 📍 Mala Aula (Faculty of Biology, AMU)
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IMBB AMU Poznań @uam-ibmib.bsky.social · 01/09/2026
Back from summer break! Join us for our Friday Institute Seminar at IMBB! 📢 "RNA processing and quality control in health and disease" 👤 Prof. Yongsheng Shi (University of California, USA) 📅 September 4, 2026 | 🕘 9:15 AM 📍 Audytorium Paczoskiego (Faculty of Biology, AMU) See you all there! 🤩
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Reposted by IMBB AMU Poznań
Sebastian Deorowicz @sdeorowicz.bsky.social · 21/07/2026
FAMSA can now be used in a web browser: refresh-bio.github.io/tools/famsa/ It is compiled to WebAssembly, so all computations run locally on the device - your data never leaves your machine. Sample timings (workstation, 16 threads) for cys family (56k seqs): 150s (default) or 20s (with medoids).
refresh-bio.github.io
FAMSA — Multiple Sequence Alignment
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IMBB AMU Poznań @uam-ibmib.bsky.social · 07/07/2026
Our second seminar this week will be on Friday! 📢 "Mechanisms controlling cellular plasticity in liver regeneration during chronic diseases" 👤 Prof. Ludovic Vallier (Max Planck Institute for Molecular Genetics, Germany) 📅 July 10, 2026 | 🕘 12:00 PM 📍 Mała Aula (Faculty of Biology, AMU)
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IMBB AMU Poznań @uam-ibmib.bsky.social · 06/07/2026
Join us for our Thursday Institute Seminar! 📢 "Watch your step: antisense oligonucleotides acting outside of genes" 👤 Prof. @grzechnikpawel.bsky.social (University of Manchester, UK) 📅 July 9, 2026 | 🕘 10:00 AM 📍 Audytorium Paczoskiego (Faculty of Biology, AMU) See you all there! 🤩
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IMBB AMU Poznań @uam-ibmib.bsky.social · 01/07/2026
🧬 New paper in Nature Structural & Molecular Biology! @agatakstepien.bsky.social, Martyna Plens-Gałąska & @stoplab.bsky.social authored a News & Views piece on transcriptional readthrough, showing how this cellular process links to anti-cancer drugs & new therapies 👏 www.nature.com/articles/s41...
nature.com
Transcriptional readthrough progresses from incidental byproduct to therapeutic opportunity - Nature Structural & Molecular Biology
Several anti-cancer drugs delay transcription termination, triggering transcriptional readthrough. Readthrough has long been considered an incidental transcriptional byproduct, however a recent study ...
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IMBB AMU Poznań @uam-ibmib.bsky.social · 29/06/2026
Join us for our Friday Institute Seminar at IMBB! 📢 "Shuffling the genetic deck: How chromosomes pair and recombine in meiosis" 👤 Prof. Simone Köhler (EMBL, Heidelberg, Germany) 📅 July 3, 2026 | 🕘 9:15 AM 📍 Audytorium Paczoskiego (Faculty of Biology, AMU) See you all there! 🤩
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Reposted by IMBB AMU Poznań
Piotr Ziolkowski @piotraz.bsky.social · 25/06/2026
⏳ Last days to register for the Plant Meiosis Meeting! Join us in Poznań for PMM 2026, with invited speakers Neil Hunter, Mathilde Grelon, André Marquez and Kyuha Choi. Raphaël Mercier, Chris Morgan, and many others also confirmed. 55 talk slots are waiting to be filled! Register: pmm.amu.edu.pl
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IMBB AMU Poznań @uam-ibmib.bsky.social · 17/06/2026
New paper in @narjournal.bsky.social! Daria Niewiadomska and Krzysztof Sobczak have uncovered new molecular mechanisms in FXPAC (#RareDiseases). The study shows how FMR1 mRNA structure & CGG repeats control toxic FMRpolyG protein stability. Congrats! 👏 academic.oup.com/nar/article/...
academic.oup.com
The role of FMR1 mRNA structure on the efficiency of non-canonical translation of toxic polyglycine protein
Abstract. Repeat-associated non-AUG (RAN) translation of mutant FMR1 messenger RNA (mRNA) containing CGG repeat expansions results in the production of a t
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IMBB AMU Poznań @uam-ibmib.bsky.social · 16/06/2026
Join us for our Friday Institute Seminar at IMBB! 📢 " Plasmodiophora brassicae and Arabidopsis thaliana interaction" 👤 Prof. Robert Malinowski (@malinowskilab.bsky.social Institute of Plant Genetics, PAS) 📅 June 19, 2026 | 🕘 9:15 AM 📍 Audytorium Paczoskiego (Faculty of Biology, AMU) See you there! 🤩
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IMBB AMU Poznań @uam-ibmib.bsky.social · 12/06/2026
Great news! Two @ncn.gov.pl OPUS grants for Katarzyna Blaszczyk and Tomasz Bieluszewski. Congratulations! 👏🎉 #IBMIB #AMU
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IMBB AMU Poznań @uam-ibmib.bsky.social · 10/06/2026
Join us for our Friday Institute Seminar at IMBB! 📢 "To B or not to B in Nucleic Acids Chemistry" 👤 Prof. Naoki Sugimoto (Konan University, Japan) 📅 June 12, 2026 | 🕘 9:15 AM 📍 Audytorium Paczoskiego (Faculty of Biology, AMU) See you all there! 🤩
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IMBB AMU Poznań @uam-ibmib.bsky.social · 03/06/2026
Next week, our institute seminar will be on Tuesday! 😀 📣 "Languages of the Non-coding Genome" 👤 Prof. Sebastian Marquardt (Lund University) 📅 June 9, 2026 | 🕘 10:00 📍 Paczoski Auditorium (Faculty of Biology) See you there! 🧬
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Reposted by IMBB AMU Poznań
Piotr Rozwalak @prozwalak.bsky.social · 11/05/2026
Mushuvirus is the most widespread phage genus in the human gut. 🌍 Together with other family members, these viruses occur in 89% of humans worldwide, including the Iceman Ötzi! How is it possible that they were hidden in previous metagenomic analyses? [1/7] Read: doi.org/10.64898/202...
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IMBB AMU Poznań @uam-ibmib.bsky.social · 11/05/2026
Join us for our Friday Institute Seminar at IMBB! 🌱 "Membrane Labyrinths of Plant Plastids – From Geometry to Biological Function" 👤 Prof. @lucjakowalewska.bsky.social (Plastid Nanomorphology Group) 📅 May 15, 2026 | 🕘 11:00 AM 📍 Audytorium Paczoskiego (Faculty of Biology, AMU) See you all there! 🤩
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IMBB AMU Poznań @uam-ibmib.bsky.social · 04/05/2026
Join us for our Friday Institute Seminar at IMBB! 🌱 "SNI1, a cold-sensitive regulator of meiotic recombination shaped by recent evolution in A. thaliana" 👤 Dr. Alexandre Pelé (IMBB, Genome Biology Research) 📅 May 8, 2026 | 🕘 9:15 AM 📍 Paczoski Auditorium (Faculty of Biology) See you there! 👋
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IMBB AMU Poznań @uam-ibmib.bsky.social · 27/04/2026
New week, insights! ✨ The team led by Kinga Kamieniarz-Gdula (@stoplab.bsky.social) reveals in EMBO Reports how SETD2 acts as a genetic "traffic controller." A vital step in understanding cancer biology! Congrats to @michal-gdula.bsky.social, @agatakstepien.bsky.social, @mgkopczynska.bsky.social! 👏
link.springer.com
SETD2 methyltransferase activity promotes correct transcription initiation and termination - EMBO Reports
SETD2 is a methyltransferase responsible for depositing histone H3 lysine 36 trimethylation (H3K36me3). Loss of its enzymatic activity occurs in some cancers, including renal cell carcinoma. SETD2 mut...
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IMBB AMU Poznań @uam-ibmib.bsky.social · 25/04/2026
Great news! 🥳 A new study from the group of @piotraz.bsky.social shows that it is possible to precisely control where meiotic recombination occurs in plant genomes using the CRISPR/dCas9 system. Now published in Science Advances! Congratulations Maja Szymańska-Lejman, Piotr Ziolkowski and the crew!
science.org
Modifying meiotic recombination by targeting chromatin regulators to crossover hotspots in Arabidopsis
Targeting chromatin modifiers to DNA hotspots reveals causal link between histone marks, transcription, and meiotic recombination.
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IMBB AMU Poznań @uam-ibmib.bsky.social · 24/04/2026
Great news! 🥳 Dr. Anna Baud with Prof. Krzysztof Sobczak showed that insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) positively regulates the noncanonical translation of expanded CGG repeats and may be a promising target for clinical applications. Published in Nature Communications!
doi.org
IGF2BPs directly regulate the noncanonical translation of toxic proteins from mutant FMR1 mRNA containing expanded CGG repeats - Nature Communications
Expanded FMR1 CGG repeats drive toxic FMRpolyG in premutation disorders. Here, the authors show that IGF2BP3 binds the FMR1 5’UTR to promote non-AUG translation of FMRpolyG and that its loss reduces t...
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IMBB AMU Poznań @uam-ibmib.bsky.social · 23/04/2026
Big news! 🥳 Joanna Szpotkowska, together with Prof. Malgorzata Borowiak, presents Glutathione Peroxidase 2 as a critical regulator of human posterior foregut differentiation, revealing oxidative stress as a key determinant of pancreatic versus non-pancreatic cell fate. Now in Nature Communications!
nature.com
Oxidative stress and GPX2 control pancreatic vs. non-pancreatic cell fate in human endoderm - Nature Communications
The role of metabolic processes in endoderm differentiation remains elusive. Here, the authors discover that oxidative stress and GPX2 determine whether human stem cells differentiate into pancreatic ...
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IMBB AMU Poznań @uam-ibmib.bsky.social · 23/04/2026
Great news from our Institute! 🎉 Dr Katarzyna Taylor has received a 2026 Early Career Grant from the Myotonic Dystrophy Foundation. Her research on MBNL1 and MBNL2 could help uncover new therapeutic targets in myotonic dystrophy type 1. Congratulations! myotonic.org/2026-grant-r...
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IMBB AMU Poznań @uam-ibmib.bsky.social · 16/04/2026
🚀 New Job Alert: Postdoctoral Fellow at IMBB! Join the Lab of Stem Cell Biology & Regenerative Medicine at Adam Mickiewicz University! 🎓 🔬 Study T2D using pancreatic organoids & multi-omics. 📍 Poznań, Poland 📑 NCN-funded OPUS project Apply here: euraxess.ec.europa.eu/jobs/428161
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IMBB AMU Poznań @uam-ibmib.bsky.social · 15/04/2026
Andrzej Zieleziński (@uam-ibmib.bsky.social) with Sebastian Deorowicz (@sdeorowicz.bsky.social), Cedric Notredame, and Adam Gudyś present FAMSA2, enabling ultra-scale multiple protein sequence alignments. Now in Nature Biotechnology! Congrats to all authors! 🎉
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IMBB AMU Poznań @uam-ibmib.bsky.social · 13/04/2026
Join us for our Friday Institute Seminar at IMBB! 🌱 "Les liaisons dangereuses: who is the winner – plants or pathogens?" 👤 Prof. Magdalena Krzymowska (IBBPAS) 📅 April 17, 2026 | 🕘 9:15 AM 📍 Paczoski Auditorium (Faculty of Biology) Don't miss it, see you there! 👋
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IMBB AMU Poznań @uam-ibmib.bsky.social · 08/04/2026
Join us for our Friday Institute Seminar at IMBB! 🌱 "Seed molecular biology" 👤 Prof. Szymon Świeżewski (IBB PAS, Warsaw) 📅 April 10, 2026 | 🕘 9:15 AM 📍 Mala Aula (Faculty of Biology, AMU) See you all there! 🤩
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IMBB AMU Poznań @uam-ibmib.bsky.social · 05/03/2026
This Friday at the @uam-ibmib.bsky.social seminar: Katarzyna Klonowska from the Institute of Biooganic Chemistry PAS in Poznan will give a talk on mutation landscape in tumour suppressor gene syndromes - join us!
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IMBB AMU Poznań @uam-ibmib.bsky.social · 05/02/2026
This Friday at the @uam-ibmib.bsky.social seminar: Urlike Topf from the Institute of Biochemistry and Biophysics PAS will give a talk on aging-dependent #oxidation of ribosomal proteins and its implications for organismal healthspan - join us!
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IMBB AMU Poznań @uam-ibmib.bsky.social · 05/02/2026
Michal Gdula group leader at @uam-ibmib.bsky.social is saerching for a postdoc to work on the epigenetics of pancreatic cancer within colaborative OPUS-LAP funded by @ncn.gov.pl and @dfg.de - reach out! #3Dgenome #cancer #pancreas
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IMBB AMU Poznań @uam-ibmib.bsky.social · 29/01/2026
This Friday @uam-ibmib.bsky.social seminar: Maja Szymańska-Lejman @szymanskalejman.bsky.social will tell us about reprogramming meiotic #recombination with dCas9 - Don't miss it! #meiosis
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IMBB AMU Poznań @uam-ibmib.bsky.social · 16/01/2026
What drives CGG RAN translation in #FXTAS? Anna Baud & Krzysztof Sobczak with Rajani Gudipatti & Malgorzata Borowiak all from @uam-ibmib.bsky.social just published at Nature Communications : IGF2BP3 regulates FMRpolyG—promising FXTAS target. www.nature.com/articles/s41...
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IMBB AMU Poznań @uam-ibmib.bsky.social · 19/12/2025
This Friday @uam-ibmib.bsky.social seminar: Magda Kopczyńska @mgkopczynska.bsky.social (@stoplab.bsky.social) on #SETD2 methyltransferase activity in gene definition and transcription regulation. Don't miss it! #epigenetics #transcriptionTermination #chromatin
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IMBB AMU Poznań @uam-ibmib.bsky.social · 10/12/2025
MAB-FENG FNP grant awarded to Krzysztof Sobczak team @uam-ibmib.bsky.social for the TREAT-EXP project! 4 groups led by Anna Baud, @michal-gdula.bsky.social, Rajani Gudipatti and K. Sobczak will work at the Centre of Adavnced Technologies on nucleotide repeat expansion diseases – congratulations!!!
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IMBB AMU Poznań @uam-ibmib.bsky.social · 04/12/2025
Join us this Friday morning for the @uam-ibmib.bsky.social seminar: Józef Dulak from the Jagiellonian University @jagiellonskiuni.bsky.social will give a talk on the modeling cardiac and muscle diseases with induced pluripotent stem cells! #IPSCs
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IMBB AMU Poznań @uam-ibmib.bsky.social · 04/12/2025
Great news for @uam-ibmib.bsky.social! Three @ncn.gov.pl OPUS grants to our researchers: @juliadluzewska.bsky.social, Wojciech Szlachcic and a collaborative Polish-German OPUS-LAP grant to @michal-gdula.bsky.social & @akispapantonis.bsky.social from @uni-goettingen.de. Big congrats to everyone!
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Reposted by IMBB AMU Poznań
Agata Stepien @agatakstepien.bsky.social · 04/12/2025
Did you know that changes in pre-mRNA 3' cleavage and RNAPII termination can go in different directions? Even more, the spacing between these two events is linked to the gene expression level❗️Check out our latest pre-print to learn more tiny.cc/330w001 1/6
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IMBB AMU Poznań @uam-ibmib.bsky.social · 13/11/2025
Join us this Friday morning for the @uam-ibmib.bsky.social seminar: Agata Starosta @agatastarosta.bsky.social from the Institute of Biochemistry and Biophysics PAS will give a talk on on translational control in #BacillusSubtilis during sporulation! #translation
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IMBB AMU Poznań @uam-ibmib.bsky.social · 06/11/2025
Join us on Friday for @uam-ibmib.bsky.social IBMiB seminar of Halina Petrykowska from our Department of Gene Expression to learn about male-specific #miRNAs whihc regulate sperm development and function in Marchantia polymorpha!
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Reposted by IMBB AMU Poznań
eLife @elife.bsky.social · 30/10/2025
1/ @reviewcommons.org, @embo.org's preprint peer review platform, is taking an important step forward. Multiple publishers, including eLife, are now jointly running the peer-review process on behalf of the platform. 🔗 buff.ly/Rm1XotK
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IMBB AMU Poznań @uam-ibmib.bsky.social · 30/10/2025
Don't miss this Friday's @uam-ibmib.bsky.social seminar! Agata Stepień from @stoplab.bsky.social & AMU Centre of Advanced Technologies presents her latest research on pre-mRNA 3' end processing and #transcriptionTermination. #RNAbiology
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IMBB AMU Poznań @uam-ibmib.bsky.social · 16/10/2025
Join us on Monday for @UAM_IBMiB seminar of Jacek Nowak from the Institute of Biochemistry and Biophysics to learn Elongation factors in synthesis of developmentally controlled non-coding RNA in Paramecium ! #ncRNA
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IMBB AMU Poznań @uam-ibmib.bsky.social · 04/09/2025
Join us on Monday for @UAM_IBMiB seminar of Takeshi Matsui from the Tokyo University of Technology to learn about keratinocyte-specific cell-death in formation of epidermal barrier! PhD students/postdocs are welcome for the cereer advice meeting! #cellDeath #corneoptosis #ID_UB
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IMBB AMU Poznań @uam-ibmib.bsky.social · 03/09/2025
🚀🧬 Exciting space science! Yeast engineered with tardigrade genes have been launched to the International Space Station for pioneering experiments by Hanna Kmita's group @uam-ibmib.bsky.social ! Check out the movie for more details! #ISS #tardigrades #space #radiation
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IMBB AMU Poznań @uam-ibmib.bsky.social · 03/09/2025
Prof. Krzysztof Sobczak , the director of the IBMiB UAM, has been elected to the prestigious group of corresponding members of the Polish Academy of Sciences - congratulations !
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IMBB AMU Poznań @uam-ibmib.bsky.social · 03/09/2025
Join us this Friday morning @uam-ibmib.bsky.social for the seminar: Prof. Kashmir Singh from the Panjab University, India will give a talk on the role of long Non-Coding RNAs in fungal infections in grapevine! #lncRNA
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IMBB AMU Poznań @uam-ibmib.bsky.social · 03/09/2025
The teams of @piotraz.bsky.social Ziółkowski from @uam-ibmib.bsky.social and Mikhail Mikhailov discovered that a natural DNA trick triples #recombination in maize! Congratulations to the authors !!! Check out the paper: lnkd.in/dh3QEFSy
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IMBB AMU Poznań @uam-ibmib.bsky.social · 03/09/2025
Congratulations to Jan Brezovsky form the @uam-ibmib.bsky.social & @iimcb.bsky.social on being recently awarded the @ncn.gov.pl OPUS-LAP research grant! His work on rational design of substrate transporters in bacteria to enhance metabolism promises exciting insights! hashtag#NCNtoTlen
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IMBB AMU Poznań @uam-ibmib.bsky.social · 25/06/2025
2nd Polish #RNA Biology Meeting in #Poznan co-organized by @uam-ibmib.bsky.social‬ has started yeaterday evening with talks of Ramesh Pillai & Sebastian Glatt @sebastianglatt.bsky.social‬ - many more great talks, posters & discussions ahead! #PolishRNABiologyMeeting
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IMBB AMU Poznań @uam-ibmib.bsky.social · 23/06/2025
Asia Kwiatkowska & Ewa Stein from Kinga Kamieniarz-Gdula Lab @stoplab.bsky.social‬ shared their expierience with insect cells culturing for protein production! Check out the paper at scientific reports: www.nature.com/articles/s41... look also at the twittorial: x.com/kwiatkowska_...
nature.com
A beginners guide to Sf9 and Sf21 insect cell line culture and troubleshooting - Scientific Reports
Scientific Reports - A beginners guide to Sf9 and Sf21 insect cell line culture and troubleshooting
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