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Steffen Grosser

@steffengrosser.bsky.social
100 followers 185 following 10 posts

Postdoc Junior Leader Fellow @Fundació ”la Caixa”, at Xavier Trepat Lab, IBEC Barcelona

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Reposted by Steffen Grosser
Sebi @sebi06.bsky.social · 19/03/2026
Hi all fans of #smart #microscopy, we from @zeiss-microscopy.bsky.social have just published a new application note: "Study Mitotic Progression with Guided Acquisition – Rare Event Detection" go2.zeiss.com/ODk2LVhNUy03... For more details: forum.image.sc/t/applicatio...
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Journal of Cell Biology @jcb.org · 19/03/2026
Deb Roy, Inoue et al. @jhu.edu introduce an #optogenetics tool to rapidly induce #microtubule acetylation in living cells and show that this triggers release of the RhoGEF GEF-H1 from #microtubules, thereby driving persistent directional cell migration. rupress.org/jcb/article/... #Cytoskeleton
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Artur @handle.invalid · 17/03/2026
First paper as first & corresponding author, out in PLOS Computational Biology! 🎉 napariTFM brings traction force & monolayer stress microscopy into napari, accessible via GUI; open-source, validated and no coding required. 😉 Check it out 👇
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Steffen Grosser @steffengrosser.bsky.social · 04/09/2025
True 😂😂 but is that how we feel? We could be so much more POLARIZING 🤩
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Steffen Grosser @steffengrosser.bsky.social · 03/09/2025
Congrats and thanks to all poster coauthors @leonerossetti.bsky.social @icfortunato.bsky.social @ricardalert.bsky.social @xaviertrepat.bsky.social -- nothing can stop us!
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Steffen Grosser @steffengrosser.bsky.social · 03/09/2025
Stoked to announce that I received a poster award! 🔥😍 Many thanks to the #25EngLife organizers for the amazing meeting!
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Steffen Grosser @steffengrosser.bsky.social · 03/09/2025
Keep an eye on the upcoming tissue force (tension) sensors 🔥🔥 from @baldaufsci.bsky.social
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Miranda Hunter @mrndhntr.bsky.social · 27/08/2025
My recent postdoctoral work is out today in @nature.com! We found that physical confinement makes melanoma cells more invasive and drug tolerant. Thanks to all who made this work possible @whitefishlab.bsky.social @mskcancercenter.bsky.social #NIH #NCI www.nature.com/articles/s41...
nature.com
Mechanical confinement governs phenotypic plasticity in melanoma - Nature
Mechanical confinement of cancer cells at the tumour–microenvironment interface induces phenotype switching through chromatin remodelling by HMGB2, leading to a more invasive and drug-resistant state ...
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Ulrich Schwarz @ulrichschwarz.bsky.social · 22/06/2025
📢Conference alert📢 Only one week left to register for the Engineering Life 2025 Symposium at Dresden September 1-3. This year's edition focuses on the function of mechanical forces in biology. engineering-life-dresden.de
engineering-life-dresden.de
Engineering Life 2025: ORIGIN AND FUNCTION OF MECHANICAL FORCES IN BIOLOGY
Engineering Life 2025, biological forces, force spectroscopy, measuring forces, developmental forces, molecular motors, forces in morphogenesis, cytoskeleton, DNA mechanics, bionanotechnology
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Hyman Lab @hymanlab.bsky.social · 23/05/2025
Great success for Dresden and Saxony! Physics of Life is one of the excellence clusters ‪@poldresden.bsky.social‬
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Reposted by Steffen Grosser
Leo Otsuki @leootsuki.bsky.social · 21/05/2025
Positional memory has implications for bioengineering. Transplanting salamander cells in a way that alters their spatial organisation changes signalling topology and results in predictable (but amazing) phenotypes such as too many fingers - or even extra limbs! 🧵3/14
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epithelial mechanics fan club @epimechfc.bsky.social · 20/04/2025
1/14 “Epithelial” & “Mesenchymal” aren’t binary categories—they form a spectrum, or better yet, a multidimensional space. This becomes especially clear in collective cell migration, which often depends on a finely tuned degree of “mesenchymal-ness”. #cellbio #devbio #cellmigration
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Journal of Cell Science @jcellsci.bsky.social · 28/03/2025
In their Review, Laura Faure, Valeria Venturini @valeriaventurini.bsky.social and Pere Roca-Cusachs discuss the biological contexts of cell mechanical compression, the associated mechanisms and the experimental systems engineered to compress cells in vitro. journals.biologists.com/jcs/article/...
Cartoon of techniques to apply one-dimensional, in-plane or volumetric cell compression in vitro.
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Reposted by Steffen Grosser
soul nate @mnateshyamalan.bsky.social · 19/03/2025
all of human knowledge at my fingertips
google search: how many r’s are in “strawberry pie”

ai overview: there are 4 r’s in the phrase “strawberry pie”:

- S: trrawbrry pie
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Steffen Grosser @steffengrosser.bsky.social · 18/03/2025
We're so back
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Steffen Grosser @steffengrosser.bsky.social · 17/03/2025
Will visit it when I am in Dresden on April 16!
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Reposted by Steffen Grosser
Microplastics Sommelier @leastactionhero.bsky.social · 27/06/2024
einstein sent this to curie in 1911 when she was being harassed by tabloids. it contains everything you’d want in such a letter: (1) your haters are trash (2) you’re a baller, a true queen (3) i have determined the statistical law of motion of the diatomic molecule in planck’s radiation field 🧪⚛️
Prague, 23 November 1911
Highly esteemed Mrs. Curie,
Do not laugh at me for writing you without having anything sensible to say.
But I am so enraged by the base manner in which the public is presently daring to concern itself with you!? that I absolutely must give vent to this feeling. However, I am convinced that you consistently despise this rabble, whether it obsequiously lavishes respect on you or whether it attempts to satiate its lust for sensationalism!
I am impelled to tell you how much I have come to admire your intellect, your drive, and your honesty, and that I consider myself lucky to have made your personal acquaintance in Brussels. Anyone who does not number among these reptiles is certainly happy, now as before, that we have such personages among us as you, and Langevin(3) too, real people with whom one feels privileged to be in contact. If the rabble continues to occupy itself with you, then simply don't read that hogwash, but rather leave it to the reptile for whom i
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Prasad Jallepalli, MD, PhD @prasad.bsky.social · 08/02/2025
this is a good time to note that the proposed candidate for NIH director has never run a lab, cared for patients, led a major research and healthcare institution, or been a principal investigator on an NIH grant
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Steffen Grosser @steffengrosser.bsky.social · 17/12/2024
The spheroid fusion analysis I did in this new study is much better than in my old paper! I don't "fit" any dumb-bell 2D shape anymore to the data (unstable). Instead, I use moment analysis/aspect ratios, which can be converted to tissue fluidity (very robust).
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Reposted by Steffen Grosser
Josquin Courte, PhD @josquincourte.bsky.social · 17/12/2024
This circuit can be used to propagate a change in cell fate in 2D in a wave-like pattern… And also in 3D! In this animation, a spheroid of “sender” cells (red+green=yellow) is fused with a spheroid of “transceiver” cells. Activated transceivers become green.
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Steffen Grosser @steffengrosser.bsky.social · 17/12/2024
And look at this stunning synthetic biology!
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Steffen Grosser @steffengrosser.bsky.social · 17/12/2024
Stunning optogenetic guidance!
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Reposted by Steffen Grosser
Xavier Trepat @xaviertrepat.bsky.social · 03/12/2024
🎈New preprint! We study how single cells move up, down and about fibronectin gradients. Experiments by @icfortunato.bsky.social, theory by David Bruckner. Collaboration with @raimonsunyer.bsky.social and @ehannezo.bsky.social 👇https://biorxiv.org/cgi/content/short/2024.12.02.626413v1
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Steffen Grosser @steffengrosser.bsky.social · 03/12/2024
Good morning, and wtf is this
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Benoit Ladoux @bladoux.bsky.social · 21/11/2024
Large-scale collective motion of epithelial cells not as a fluid, but as a polar elastic solid. Our new study posted on Biorxiv: www.biorxiv.org/content/10.1...
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Kirsty Wan @micromotility.bsky.social · 13/11/2024
Couldn't find one so made a quick physics of life list, enjoy! go.bsky.app/EA2VsDN
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