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Hyman Lab

@hymanlab.bsky.social
1.6K followers 561 following 53 posts

Science and fun from the lab of Tony Hyman at the MPI-CBG @mpicbg.bsky.social. Tweets by Hymanlab members. hymanlab.org

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Max Planck Institute of Molecular Cell Biology and Genetics @mpi-cbg.de · 30/06/2026
A very hot and long night packed with science! A big thank you to our 100 amazing volunteers and 700 guests! www.mpi-cbg.de/news-outreac...
mpi-cbg.de
A very hot and long night packed with science
MPI-CBG part of Dresden Science Night
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Max Planck Institute of Molecular Cell Biology and Genetics @mpi-cbg.de · 01/07/2026
Today, we remembered Marwa El-Sherbini at the institute and in front of the regional court, where a new stele commemorates Marwa. Marwa, the wife of former MPI-CBG PhD student Elwy, was stabbed to death and Elwy got injured at an appeal hearing in the Court. Our thoughts are with her family.
White roses in a vaseStele for Marwa with flowers.
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Max Planck Institute of Molecular Cell Biology and Genetics @mpi-cbg.de · 05/06/2026
Watch the science behind the 2023 Breakthrough Prize for Anthony Hyman @mpi-cbg.de & @embl.org and Clifford Brangwynne @princetonupress.bsky.social & @hhmi-science.bsky.social. www.youtube.com/watch?v=3Exd...
youtube.com
BEYOND THE WALLS: Cliff Brangwynne and Anthony Hyman Discover a New Cellular Process
YouTube video by Breakthrough
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Alexey Amunts @amunts.bsky.social · 13/05/2026
Delighted to welcome our new PI, Daxiao Sun who is starting her lab at SMART after a postdoc with @hymanlab.bsky.social @mpi-cbg.de and Alf Honigmann @biotec-tud.bsky.social Daxiao’s group will investigate how biomolecular condensates regulate cell junctions and tissue morphogenesis. Welcome!
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Max Planck Institute of Molecular Cell Biology and Genetics @mpi-cbg.de · 29/04/2026
Anthony Hyman @embl.org & @mpi-cbg.de @hymanlab.bsky.social & Clifford Brangwynne @princetonupress.bsky.social & @hhmi-science.bsky.social receive their 2023 Breakthrough Prize at the Awards Ceremony in Santa Monica,LA, April 18, by Eileen Gu & @mrgatoasdf.bsky.social! www.mpi-cbg.de/news-outreac...
mpi-cbg.de
Breakthrough Prize Award Ceremony
Antony Hyman and Clifford Brangwynne receive their 2023 Breakthrough Prize
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Theresia Gutmann @thegutmann.bsky.social · 27/04/2026
Heartfelt congratulations to our new PhD student Silja Zedlitz on receiving the Rainer Rudolph Award 2025 for her MSc thesis in the lab of @kjohnsson.bsky.social on minimal rhodamine probes for protein labeling in cells. @hymanlab.bsky.social @mpi-cbg.de @gbmev.bsky.social @mpi-mr.bsky.social
Johannes Buchner, Silja Zedlitz, and Johannes Hermann at the Mosbacher Kolloquium of the GBM.
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André Nadler @nadlerlab.bsky.social · 23/03/2026
It’s incredibly hard to study lipids in biological membranes on the nanoscale. You need near-perfect information on both membrane ultrastructure and lipid density. Lipid-CLEM, now out in @natcellbio.nature.com brought to you by @mathilda95.bsky.social changes that: www.nature.com/articles/s41...
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Max Planck Institute of Molecular Cell Biology and Genetics @mpi-cbg.de · 17/12/2025
Researchers from @merihuchlab.bsky.social, together with colleagues from @labshevchenko.bsky.social and clinicians from Dresden and Leipzig developed a patient-specific human periportal liver assembloid. Publication in @nature.com. Full news: www.mpi-cbg.de/news-outreac...
mpi-cbg.de
Patient-specific human liver model to understand disease mechanisms
Dresden research team develops human modular “LEGO-like” model that lays foundation for a new era in liver research.
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Hyman Lab @hymanlab.bsky.social · 17/12/2025
Congratulations and merry christmas!
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Hyman Lab @hymanlab.bsky.social · 11/12/2025
Congratulations from Dresden!!!
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Toth-Petroczy lab @tothpetroczylab.bsky.social · 01/12/2025
I am honored and proud to work with my amazing group @mpi-cbg.de and @csbdresden.bsky.social 🥰 🧬. Thanks to all my colleagues for the wonderful scientific environment. And thank you @kboes.bsky.social for preparing this superb video! 🤩
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Hyman Lab @hymanlab.bsky.social · 28/11/2025
Congratulations Theresia!!!
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CrowDsourcing COndensate Database & Encyclopedia @cdcode.bsky.social · 14/11/2025
CD-CODE 2.0 is now published in @narjournal.bsky.social 🤩 CD-CODE 2.0 stores #biomolecular #condensates and their #protein and nucleic acid components and now includes repository of 🦠 infectious condensates, 💊 condensate-modulating compounds, and 🩺 condensatopathies 👀 doi.org/10.1093/nar/...
puzzle pieces are connected to represent CD-CODE database concept. landscape orientation (4 puzzle pieces top row, 5 puzzle pieces lower row). Top row: puzzles representing applicability, API, infectious condensate with logo representing pathogen cell and condensate, condensatopathies with a stethoscope logo, text: CD-CODE CrowDSourcing Condensate Database and Encyclopedia. Bottom tow: puzzles representing community, CD-CODE logo, Biomolecualr condensates with logos for species (human, frog, mouse), c-mods with chemical compound logo, DNA, proteins, RNA minimalistic logos.
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Grill Lab @ MPI-CBG @grill-lab.bsky.social · 06/11/2025
The Lab of Stephan Grill at MPI-CBG has finally made it to Bluesky and we also have a brand new homepage: grill-lab.org Check it out.
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Hyman Lab @hymanlab.bsky.social · 29/10/2025
We had a good line up of speakers at the 50 years anniversary meeting of the german society of cell biology @dgz.bsky.social in Heidelberg. Tony gave the plenary, Koichiro talked about spatial control of P granules and Silja received a price for her Master thesis and gave a talk. Congratulations!
Silja used rhodamine probes for protein labeling in cellsTony giving the plenary on phase separation in physiology and diseaseSilja receiving her price for her Master's thesisKoichiro talking about spatial control of P granules
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Hyman Lab @hymanlab.bsky.social · 29/10/2025
Congratulations to our PhD student David @rnadavid.bsky.social for his successful defense of his PhD thesis! @mpi-cbg.de imprs.mpi-cbg.de As you see the lab was very creative with his hat! David gave his insights on the nucleocapsid protein and even better arranged a great buffet for celebrations!
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André Nadler @nadlerlab.bsky.social · 09/10/2025
Lipid imaging on the cover of @nature.com! Great times for lipid cell biology indeed. And a fantastic recognition of all the hard work by the team, especially Juan M. Iglesias-Artola and Kristin Böhlig (who made the cover). Link to article: www.nature.com/articles/s41...
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Hyman Lab @hymanlab.bsky.social · 19/09/2025
🤌
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Hyman Lab @hymanlab.bsky.social · 19/09/2025
Very good news in the local press! The Ig Nobel goes to Dresden 😎 www.saechsische.de/lokales/dres...
saechsische.de
Dresdner Forscher gewinnen besonderen Nobelpreis für Pastasauce
Kuriose wissenschaftliche Studien sind mit den Ig-Nobelpreisen in den USA geehrt worden. Auch Forscher vom Max-Planck-Institut in Dresden wurden ausgezeichnet.
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Hyman Lab @hymanlab.bsky.social · 16/09/2025
Have a look at Lars @larshubatsch.bsky.social reviewed preprint in @elife.bsky.social and learn about the kinetics of molecule transport across interfaces of condensates!
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Hyman Lab @hymanlab.bsky.social · 05/09/2025
Congratulations to Patrick and his team! Tremendous work carried out over the last years @mpi-cbg.de and @poldresden.bsky.social as collaboration between Hyman lab, Brugues lab and Andrei Shevchenko
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André Nadler @nadlerlab.bsky.social · 03/09/2025
This is an amazing piece of work! It was a true pleasure seeing this story come together. @mpi-cbg.de going on a streak of @nature.com papers!
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André Nadler @nadlerlab.bsky.social · 21/08/2025
Out today in @nature.com: Together with the Honigmann, Shevchenko, Drobot and Hof labs, we present a general workflow for imaging the localization and transport of individual lipids in cells and mapping their metabolism. www.nature.com/articles/s41...
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Max Planck School Matter to Life @mattertolife.bsky.social · 16/07/2025
The recent publication from MtL fellow @hymanlab.bsky.social has described a quantitative framework for condensate stability and dissolution, in the context of RNA binding protein MEX-5 and P-granules. Congratulations to MtL Student Silja Zedlitz for being a co-author! www.pnas.org/doi/10.1073/...
pnas.org
A mechanism for MEX-5-driven disassembly of PGL-3/RNA condensates in vitro | PNAS
MEX-5 regulates the formation and dissolution of P granules in Caenorhabditis elegans embryos, yet the thermodynamic basis of its activity remains ...
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Max Planck Institute of Molecular Cell Biology and Genetics @mpi-cbg.de · 26/06/2025
Novel Research in Biological Artificial Intelligence: Expressions of interest and nominations for a Max Planck Director to lead research in the field of Biological Artificial Intelligence @mpi-cbg.de and @csbdresden.bsky.social. More information: www.mpi-cbg.de/news-outreac...
mpi-cbg.de
Novel Research in Biological Artificial Intelligence
Expressions of interest and nominations for a Max Planck Director to lead research in the field of Biological Artificial Intelligence.
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Max Planck Institute of Molecular Cell Biology and Genetics @mpi-cbg.de · 25/06/2025
How to spy on condensates: technology feature in @natmethods.nature.com on self-organization and collective properties of condensates with quotes from Anthony Hyman @hymanlab.bsky.social @mpi-cbg.de, @brangwynnelab.bsky.social, and many more. www.nature.com/articles/s41...
nature.com
How to spy on condensates - Nature Methods
Scientists track how these membraneless biomolecular foci self-organize for their cellular tasks.
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Max Planck Institute of Molecular Cell Biology and Genetics @mpi-cbg.de · 24/06/2025
Dresden scientists @thegutmann.bsky.social and @rnadavid.bsky.social from the @hymanlab.bsky.social discover a new strategy used by the SARS-CoV-2 virus to hide from the body’s DNA immune detection system. Now published in @pnas.org. www.mpi-cbg.de/news-outreac...
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Hyman Lab @hymanlab.bsky.social · 24/06/2025
How could SARS-COV-2 evade detection by host cells? Read the new paper from Theresia @thegutmann.bsky.social and David @rnadavid.bsky.social discussing how the nucleocapsid protein prevents recognition of the innate immunity sensor cGAS Congratulations!!! ‬
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Physics of Life Dresden @poldresden.bsky.social · 18/06/2025
Big news 🎉 We are excited to announce the new TUD graduate school "Biomolecular Condensates: From Physics to Biological Functions", with 12 members from PoL! Through this school, we will train a new generation of scientists working on #condensates at the interphase between theory and experiments 🤓⤵️
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Max Planck Institute of Molecular Cell Biology and Genetics @mpi-cbg.de · 18/06/2025
Visit us during the Dresden Science Night on June 20th in the Faculty of Physics @tudresden.bsky.social (Hermann-Krone-Bau, Nöthnitzer Straße 61) and explore the physics of life! Looking forward to see you! www.mpi-cbg.de/news-outreac...
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GBM (Gesellschaft für Biochemie und Molekularbiologie) @gbmev.bsky.social · 16/06/2025
We're excited to welcome Dresden's scientific community to the GBM Compact Meeting in Frankfurt! #CodensateBiology gbm-compact.org
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Hyman Lab @hymanlab.bsky.social · 16/06/2025
The german research foundation DFG will fund the new graduate school for "Biomolecular Condensates: from physics to biological function" here in Dresden This new graduate school is part of 18 new graduate schools funded by the DFG in germany!
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CrowDsourcing COndensate Database & Encyclopedia @cdcode.bsky.social · 11/06/2025
The latest release was supported by the #condesathon joined by @mpi-cbg.de condensate community🤩 Big #thankyou to all the participants from @hymanlab.bsky.social, @tothpetroczylab.bsky.social and von Appen labs for your support and enthusiasm!💜
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Hyman Lab @hymanlab.bsky.social · 04/06/2025
We had great fun with the lab!
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Max Planck Institute of Molecular Cell Biology and Genetics @mpi-cbg.de · 28/05/2025
Condensates Inside Condensates—Triggering Disease? New Insights into TDP-43 Condensation and Neurodegeneration. Publication from the @hymanlab.bsky.social in @cellpress.bsky.social, first author: @xiaoyan52802927.bsky.social www.mpi-cbg.de/news-outreac...
mpi-cbg.de
Condensates Inside Condensates—Triggering Disease?
New Insights into TDP-43 Condensation and Neurodegeneration
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Max Planck Institute of Molecular Cell Biology and Genetics @mpi-cbg.de · 27/05/2025
Watch the related Science Sketch video: youtu.be/uBpPMyVTj5c?..., created by @marionamec.bsky.social
youtu.be
Molecule Disarms Cellular Stress Granules Linked to ALS
YouTube video by MPI-CBG
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Max Planck Institute of Molecular Cell Biology and Genetics @mpi-cbg.de · 27/05/2025
A team @mpi-cbg.de from @hymanlab.bsky.social & the @edinburghup.bsky.social (Richard Wheeler group) has identified the molecule lipoamide that can prevent the formation of pathological stress granules - protein-rich condensates associated with cellular stress and ALS. www.mpi-cbg.de/news-outreac...
mpi-cbg.de
Molecule Disarms Cellular Stress Granules Linked to ALS
Discovery by researchers in Dresden and Edinburgh points to new understanding of the onset of ALS.
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Hyman Lab @hymanlab.bsky.social · 23/05/2025
We are very happy that XiaoYan's (Andy!) paper is out, congratulations to all authors @cellpress.bsky.social @xiaoyan52802927.bsky.social www.cell.com/cell/fulltex... Demixing of TDP-43 inside stress granules generates pathological aggregates linked to ALS/FTD @mpi-cbg.de @biotec-tud.bsky.social
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Hyman Lab @hymanlab.bsky.social · 23/05/2025
Great success for Dresden and Saxony! Physics of Life is one of the excellence clusters ‪@poldresden.bsky.social‬
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Hyman Lab @hymanlab.bsky.social · 21/05/2025
Congratulations to Yuri! Very happy to have her in the lab!
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Simone Reber @simonereber.bsky.social · 19/05/2025
✨We are looking for a PhD student interested in physical cell bio, imaging 🔬, biochemistry, #Xenopus 🐸 & #microtubules ✨ Join us @mpiib-berlin.mpg.de!
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Hiroyuki Uechi @hiro-cg5445.bsky.social · 15/05/2025
Some small molecules modulate protein condensation in cells, but how? Our latest work shows a possible mechanism of action of the small molecule lipoamide. This molecule prevents condensation of stress granules whose components are found as protein aggregates in ALS. www.nature.com/articles/s41...
nature.com
Small-molecule dissolution of stress granules by redox modulation benefits ALS models - Nature Chemical Biology
Uechi et al. found that a small-molecule lipoamide dissolves stress granules (SGs) by targeting SFPQ, a redox-sensitive disordered SG protein, alleviating pathological phenotypes caused by amyotrophic...
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Hyman Lab @hymanlab.bsky.social · 14/05/2025
Hiro's paper is out! @hiro-cg5445.bsky.social Collaboration and Tour de Force with Richard Wheeler @zephyris-science.bsky.social and many other coauthors. Big congratulations and thank you to anyone involved! www.nature.com/articles/s41...
nature.com
Small-molecule dissolution of stress granules by redox modulation benefits ALS models - Nature Chemical Biology
Uechi et al. found that a small-molecule lipoamide dissolves stress granules (SGs) by targeting SFPQ, a redox-sensitive disordered SG protein, alleviating pathological phenotypes caused by amyotrophic...
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CrowDsourcing COndensate Database & Encyclopedia @cdcode.bsky.social · 28/04/2025
We're really excited that CD-CODE is now cross-referenced by #UniProt and has already been included in the latest release: www.uniprot.org/release-note... Spreading knowledge about #biomolecular #condensates 🥳 @ebi.embl.org @sib.swiss @mpi-cbg.de @tothpetroczylab.bsky.social @hymanlab.bsky.social
uniprot.org
UniProt
UniProt is the world's leading high-quality, comprehensive and freely accessible resource of protein sequence and functional information.
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Hyman Lab @hymanlab.bsky.social · 10/04/2025
:-)
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Hyman Lab @hymanlab.bsky.social · 01/04/2025
read the words of Victor Ambros!
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Max Planck School Matter to Life @mattertolife.bsky.social · 14/03/2025
🚀 Great news! With support of the Dieter Schwarz Foundation, the #MaxPlanckSchools will keep growing. The funding boosts top-tier research & training—#ShapingTheFuture of science! Read more at bit.ly/3DQR9NZ @maxplanck.de @unigoettingen.bsky.social @uniheidelberg.bsky.social @tum.de
An open palm with a launching rocket, surrounded by symbols such as light bulbs and gears
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Hyman Lab @hymanlab.bsky.social · 13/03/2025
Great to see the David's @rnadavid.bsky.social talk at the RNA binding protein meeting at the @embl.org Heidelberg live in Dresden in the lab! What drives demixing of TDP-43? #EMBLRBP @events.embl.org
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Hyman Lab @hymanlab.bsky.social · 03/03/2025
!!!
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Hyman Lab @hymanlab.bsky.social · 12/02/2025
Learn about the differences of noise buffering and noise reduction mediated by biomolecular condensates. A report from our former colleague Chris Zechner and Frank Jülicher from the MPI-PKS @zechnerlab.bsky.social @mpipks.bsky.social @poldresden.bsky.social
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