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Josquin Courte, PhD

@josquincourte.bsky.social

240 followers 858 following 44 posts

Scientist. Microfluidics, synthetic biology, neurodegeneration, tissue engineering. I want to develop better in vitro disease models. Currently looking for positions in the biotech sector in Switzerland / France / Belgium. Also DM, TTRPG enthusiast.

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Josquin Courte, PhD @josquincourte.bsky.social · 20/01/2025

#HelloQuitteX #20Janvier

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Josquin Courte, PhD @josquincourte.bsky.social · 17/12/2024

Delighted to share our last preprint!!! 🎉🎉🎉 biorxiv.org/content/10.1101/2024.12.11.627621v1 We share the first synthetic gene circuit guiding the self-organization of mammalian tissues in elongating structures by dynamically tuning growth, viscosity and adhesion.

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Josquin Courte, PhD @josquincourte.bsky.social · 06/12/2024

An exciting result about controling signaling with density (doi.org/10.1038/s41467-024-53078-8) => As distal parts of rod-shaped aggregates are less dense., we get "free" spatial patterning in 3D! => Some interesting potential for feedback loops, if this circuit controls tissue physics...

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Josquin Courte, PhD @josquincourte.bsky.social · 25/11/2024

I am thrilled to share that our work is finally published in Nature Communications!!! 🎉 🎉 🎉 I had the honor of leading the project to its finish line during my last years at USC, building on the groundbreaking work of my co-first authors Pranav Bhamidipati and Marco Santorelli. (1/n)

nature.com

Control of spatio-temporal patterning via cell growth in a multicellular synthetic gene circuit - Nature Communications

A major goal in synthetic development is to build gene regulatory circuits that control patterning. Here the authors discover that elevated cell density dampens SynNotch signaling, enabling the design...

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