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Ryo Harada

@ryoharada.bsky.social
47 followers 24 following 1 posts

Postdoc at Ryoma’s lab, Kyoto University Phylogenomics, Eukaryotic Evolution, Symbiosis Tsukuba -> Dalhousie -> Kyoto

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Reposted by Ryo Harada
Andrew Roger @andrewjroger.bsky.social · 19/06/2026
1/ Deep-time phylogenetics is hard: overly simplistic substitution models can mislead tree estimation at the billion year timescale. Our new preprint introduces GTRspmix, a protein modeling framework designed to more realistically model site-to-site heterogeneity in amino acid replacement. 🧵
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Reposted by Ryo Harada
Andrew Roger @andrewjroger.bsky.social · 28/05/2026
1/ Our new paper in Systematic Biology "Modeling Site-and-Branch-Heterogeneity with GFmix" led by @cgpmcc.bsky.social describes improved ways to model compositional heterogeneity across both sites and branches—an important source of error in deep phylogenomics. doi.org/10.1093/sysb...
doi.org
Modeling Site-and-Branch-Heterogeneity with GFmix
Abstract. Phylogenetic trees are often inferred from protein sequences sampled from diverse taxa across the tree of life. The compositions of these amino a
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Reposted by Ryo Harada
Courtney Stairs @cstairs.bsky.social · 11/05/2026
Have you registered for CGUE yet? Head on over to comparativegenomics2026.com Registration includes all meals and hotel nights.
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Reposted by Ryo Harada
Andrew Roger @andrewjroger.bsky.social · 06/05/2026
IQ-TREE 3: Phylogenomic Inference Software using Complex Evolutionary Models academic.oup.com/mbe/article/...
academic.oup.com
IQ-TREE 3: Phylogenomic Inference Software using Complex Evolutionary Models
Abstract. IQ-TREE (https://iqtree.github.io/) is a widely used open-source software tool for efficiently inferring phylogenetic trees under maximum likelih
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Reposted by Ryo Harada
Wen-Cong Huang @wentsunghwang.bsky.social · 13/11/2025
#Archaea, #DPANN, #phylogenetic_reconciliation New preprint online! www.biorxiv.org/content/10.1...
biorxiv.org
Phylogenetic reconciliation supports a methanogenic ancestor of the Archaea and a derived origin for host-associated lineages
The phylogeny of the Archaea continues to be revisited and revised as new groups are discovered and phylogenetic methods improve, but key questions about their early evolution remain. It has been sugg...
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Reposted by Ryo Harada
Ryuji Yanase @ryanase.bsky.social · 28/08/2025
Pleased to share our new preprint: "Plasmodium ARK1 regulates spindle formation during atypical mitosis and forms a divergent chromosomal passenger complex". Many thanks to our collaborators. @ritatewari.bsky.social @eelcotromer.bsky.social @davidguttery.bsky.social www.biorxiv.org/content/10.1...
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Reposted by Ryo Harada
Andrew Roger @andrewjroger.bsky.social · 12/08/2025
Our paper describing our new improved GFmix models for phylogenetic inference that capture site-and-branch heterogeneity in amino acid composition. www.biorxiv.org/content/10.1...
biorxiv.org
Modeling site-and-branch-heterogeneity with GFmix
Phylogenetic trees are often inferred from protein sequences sampled from diverse taxa across the tree of life. The compositions of these amino acid sequences may be heterogeneous across both sites an...
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Reposted by Ryo Harada
bioRxiv Evolutionary Biology @biorxiv-evobio.bsky.social · 10/08/2025
Modeling site-and-branch-heterogeneity with GFmix www.biorxiv.org/content/10.1101/202…
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Reposted by Ryo Harada
bioRxiv Evolutionary Biology @biorxiv-evobio.bsky.social · 11/05/2025
Phylogenetic dissection provides insights into the incongruity in the tree of Archaeplastida between the analyses of nucleus- and plastid-encoded proteins. www.biorxiv.org/content/10.1101/202…
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Reposted by Ryo Harada
Andrew Roger @andrewjroger.bsky.social · 06/05/2025
Eukfinder: a pipeline to retrieve microbial eukaryote genome sequences from metagenomic data | mBio journals.asm.org/doi/10.1128/...
journals.asm.org
Eukfinder: a pipeline to retrieve microbial eukaryote genome sequences from metagenomic data | mBio
Advancements in next-generation sequencing have made whole-genome shotgun (WGS) metagenomic sequencing an efficient method for de novo reconstruction of microbial genomes from various environments. Th...
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Ryo Harada @ryoharada.bsky.social · 03/05/2025
New paper out! We discovered a tiny archaeon with the smallest known archaeal genome — only 238 kbp! Candidatus Sukunaarchaeum mirabile has almost no recognizable metabolic pathways and may rely heavily on a host to survive. It also represents a novel, deep-branching lineage in the archaeal tree.
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Reposted by Ryo Harada
bioRxiv Evolutionary Biology @biorxiv-evobio.bsky.social · 02/05/2025
A cellular entity retaining only its replicative core: Hidden archaeal lineage with an ultra-reduced genome www.biorxiv.org/content/10.1101/202…
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