Published in Nucleus (Vol. 17, No. 1, 2026)

Wickström discovered how cells sense the physical world around them. Her research showed that cells can “feel” forces such as pressure and stretching and relay these signals all the way to their DNA. ...

Sara Wickström receives the Körber Prize for groundbreaking discoveries in cell biology The Finnish medical doctor and cell biologist Sara Wickström, Director at the Max Planck Institute for Molecular...

McCreery, Stubb et al. show that mechano-osmotic changes in the nucleus induce general transcriptional repression and prime chromatin for cell fate transitions by relieving repression of specific diff...

Why mammals cannot regenerate limbs like amphibians do presents a long-standing puzzle in biology. To uncover the underlying differences, we compared amputation responses of embryonic mouse (Mus musculus) and Xenopus laevis tadpole limbs. Lowering ...

Xu et al. uncover how metabolites regulate cellular communication during inflammatory resolution and tissue repair in vivo. They find that glutamine metabolism alters chromatin accessibility and suppr...