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I wanted to like QED's new 1% ranking. I don't.

Specialized cell types and links to psychiatric disorders are revealed by genetic mapping of primate amygdala neurons.

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Scientific research requires taking risks, so why does much funded scientific research play it safe? This study uses an economic contracting model to argue that this can be explained in part by the no...

Super-enhancers (SEs) are clusters of enhancers with high transcriptional activity that play essential roles in defining cell identity through regulation of nearby genes. SEs preferentially form multi...

Single-cell RNA-seq facilitates the study of transcriptome diversity in individual cells. Here, authors introduce a tool for isoform quantification at the single-cell level using 3’ scRNA-seq data, co...

The REX element is associated with long-range enhancer–promoter interactions.

Vacancy at Department of Molecular Biology and Genetics - RNA Biology and Innovation, Aarhus University

The MRC Laboratory of Medical Sciences (LMS) is a biomedical research institute where scientists and clinicians collaborate to advance the understanding of biology and its application to medicine. LMS...

When researchers cede their scientific judgement to machines, we lose something important.

Join a global community of excellence Are you a bold, creative researcher ready to shape the future of medical science? Karolinska Institutet (KI), one of the world’s foremost medical universities,

Kim et al. map gene regulatory networks of the developing mouse hypothalamus and prethalamus using single-cell multiomics, identifying regulators of regionalization and neurogenesis. They further show...

Nature Genetics - Combining functional genomic data from mouse and chicken with a synteny-based strategy identifies positionally conserved cis-regulatory elements in the absence of direct sequence...

Chromatin plays a pivotal role in genome expression, maintenance, and replication. To better understand chromatin organization, we developed a novel proximity-tagging method which assigns unique DNA b...

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