This protocol enables rigorous and reproducible quantification of prokaryotic concentration in stool samples by 16S rRNA qPCR or ddPCR.

Mathematical models can distil complex systems into their key components, posit theories that spark experimental research and forecast future events. We discuss the power of models to address pressing...

Background Alterations in the composition and function of the intestinal microbiota have been observed in organismal aging across a broad spectrum of animal phyla. Recent findings, which have been der...

A multi-omics approach reveals host–microbiome interactions in aging in mice.

Scientific Data - Multi-omic stock of surface ocean microbiome built by monthly, weekly and daily sampling in Dapeng Bay, China

Interpretation and visualization of microbiome charts - YongxinLiu/MicrobiomeStatPlot

Diener et al. present a method that allows the estimation of dietary intake from human stool by detecting food-derived DNA in faecal metagenomes.

Scientific Reports - Temporal stability and lack of variance in microbiome composition and functionality in fit recreational athletes

Nature Reviews Gastroenterology & Hepatology, Published online: 04 February 2025; doi:10.1038/s41575-025-01040-4A study in Nature Medicine developed a new clinical test based on a gut metagenome-derived multispecies biomarker panel for the diagnosis of…

Women’s health is essential to global societal and economic wellbeing, yet health disparities remain prevalent. The vaginal microbiota plays a critical role in health, with research indicating that re...

In this meta-analysis, the authors compile results from 60 years of chemotaxis research into a database of prokaryotic chemoeffectors that compares and analyses their effects as attractant, repellent ...

The discovery that other vertebrates have healthy, microbial brains is fueling the still controversial possibility that we might have them as well.

Reanalysis of 12,262 longitudinal infant gut microbiome samples using the Marker-MAGu pipeline revealed phage–bacteria dynamics over the first year of life.

Reanalysis of 12,262 longitudinal infant gut microbiome samples using the Marker-MAGu pipeline revealed phage–bacteria dynamics over the first year of life.

Yang et al. show an age-related increase in the microbial-derived metabolite phenylacetylglutamine that drives host cellular senescence by inducing DNA damage and mitochondrial dysfunction via ADR–AMP...

Predicting invasion outcomes in microbial communities is challenging. Here the authors demonstrate that these outcomes in both theoretical and experimental microbial communities can be predicted based...

Thousands of metagenome-assembled genomes from the Vanishing Glaciers project showcase the interactions between prokaryotes, algae, fungi and viruses in glacier-fed stream environments.

Phylowave, an innovative phylogenetic approach, can identify the main circulating pathogen lineages with increased fitness and the associated genetic changes, enabling the timely identification of…

Metagenomic immunoglobulin sequencing (MIg-seq) uncovered patterns of IgA antibody binding of bacterial strains in the healthy human gut microbiome.

A long-term metagenomic time series reveals how viruses impact diversity, ecological dynamics and evolution of freshwater microbiomes.

Results of multi-omic profiling of the microbiome and host immunity of individuals treated with VE303 to prevent recurrent Clostridioides difficile infection in the context of a phase 2 trial show rob...

PhD Project - Decoding Early Life Microbiota and Host Interactions at University of Birmingham, listed on FindAPhD.com

Animals selectively acquire specific symbiotic gut bacteria from their environments that aid host fitness. To colonize, a symbiont must locate its niche and sustain growth within the gut. Adhesins are...

Caty et al. demonstrate that alkaloids play a role in structuring the skin microbial community of dendrobatid poison frogs. They provide evidence that this is partly due to the ability of some microbial taxa to metabolize alkaloids.

In this Review, Shepherd, Brockhurst and colleagues explore the clinical evidence in support of four major ecological and evolutionary mechanisms of within-patient antimicrobial resistance emergence i...

Engineering Turing patterns has been one of the most challenging problems in synthetic biology because even tiny changes in the reaction parameters destroy patterning. Here, the authors construct a mo...

Strain richness of gut microbiota ecosystems is a key characteristic underpinning engraftment in faecal microbiota transplantation, and could improve the design of defined live biotherapeuti...