Buck Samuel 🪱🦠🧬🔬 @microbeminded.bsky.social · 11/06/2026Derailed and delayed by weather in Chicago yesterday, but excited to catch up with everyone at C. elegans #MAPSS + #DevCell 2026 today!! 0120
Reposted by Buck Samuel 🪱🦠🧬🔬Javier Apfeld @javierapfeld.bsky.social · 27/05/2026Worm friends, we need your help! For the next C. elegans Mentor Match cycle, we’re gathering testimonials from past mentors and mentees. One of our biggest challenges is recruiting new mentees, and hearing directly from past participants could really help. Please record a short video, and share!padlet.comC. elegans Mentor Match TestimonialsMade with Padlet 01518
Reposted by Buck Samuel 🪱🦠🧬🔬Needhi Bhalla 💅🏽 @needhibhalla.bsky.social · 27/05/2026"Currently proposed policies are likely to lead to ~1000 (~10%) fewer new and competing grants being funded in fiscal year 2026 than would have been funded in years with historically normal levels of multiyear funding." goodscience.substack.com/p/understand...goodscience.substack.comUnderstanding and Modeling NIH Research Grant Success Rates and the Impact of “Multiyear Funding”This is a guest post from Jeremy M. 0127
Reposted by Buck Samuel 🪱🦠🧬🔬Jeremy Berg @jeremymberg.bsky.social · 27/05/2026So... I got more information about this plan. The most important points follow on the next posts. 1/3 77776
Reposted by Buck Samuel 🪱🦠🧬🔬Jess Calarco @jessicacalarco.com · 29/05/2026This is bad. Bad for researchers. Bad for science. Bad for universities. Bad for professional associations. For example: 1. Every award would be vetted by political appointees, who could overrule peer reviewers and deny the award if it doesn't advance the president's priorities. 1/🧵 541924844
Buck Samuel 🪱🦠🧬🔬 @microbeminded.bsky.social · 09/05/2026Opening for a #postdocjob in modeling of #genetics of host- #microbiome interactions in #Celegans at @bcmhouston.bsky.social — take a look here: www.linkedin.com/jobs/view/44... Questions or apply via cover letter, CV, and references to bucks [at] bcm.edu . Hiring ASAP! #microsky #jobs 🦠🪱🧬linkedin.comBaylor College of Medicine hiring Postdoctoral Fellow in Genetics of Host-Microbiome Interactions in Houston, TX | LinkedInPosted 7:15:27 PM. Company DescriptionBaylor College of Medicine, located in the Texas Medical Center in Houston, is…See this and similar jobs on LinkedIn. 11221
Reposted by Buck Samuel 🪱🦠🧬🔬Kavita Babu @kavita-babu.bsky.social · 07/05/2026So great to see @usbumer1's cool story out at @commsbio.nature.com! Funding thanks DBT and India Alliance. Umer et al have found a role for the neuropeptide FLP-15 in worm foraging. Thanks to all authors and our collaborators @monikakscholz.bsky.social lab. www.nature.com/articles/s42...nature.comFLP-15 functions through the GPCR NPR-3 to regulate local and global search behaviours in Caenorhabditis elegans - Communications BiologyFLP-15 neuropeptide regulates foraging in C. elegans via NPR-3 in dopaminergic neurons, controlling reversal dynamics and spatial exploration during off-food search 063
Reposted by Buck Samuel 🪱🦠🧬🔬Gavin Woodruff @weirdworms.bsky.social · 08/05/2026WormTagDB: a systematic survey of endogenously tagged proteins in Caenorhabditis elegans and roadmap toward the tagged proteome academic.oup.com/g3journal/ad...academic.oup.comWormTagDB: a systematic survey of endogenously tagged proteins in Caenorhabditis elegans and roadmap toward the tagged proteomeAbstract. Endogenous protein tagging in Caenorhabditis elegans enables the direct visualization and manipulation of proteins in vivo, providing native read 0114
Reposted by Buck Samuel 🪱🦠🧬🔬The New York Times @nytimes.com · 05/05/2026Breaking News: The FDA has blocked publication of research that found widely used Covid-19 and shingles vaccines were safe.nyti.msF.D.A. Blocked Publication of Research Finding Covid and Shingles Vaccines Were SafeThe agency’s scientists and data contractors reviewed millions of patient records for studies that were pulled back before release. 27487292
Reposted by Buck Samuel 🪱🦠🧬🔬Talmo Pereira @talmo.bsky.social · 05/05/2026We tracked mice in space! This video shows our estimate of their self-induced centripetal force during circling in 3D 👩🚀 Preprint thread below 👇 37733
Reposted by Buck Samuel 🪱🦠🧬🔬Antebi Lab @antebilab.bsky.social · 04/05/2026🚨Publication @micropub7n.bsky.social www.micropublication.org/journals/bio... PoC study by Y. Park: deconvolving the C. elegans proteome to organ- & tissue-level ageing trajectories expands the use of single-worm proteomics data as a powerful tool to study dynamic cellular changes during ageing.micropublication.orgDeconvolution of Single-Organism Omics Resolves Cellular and Tissue Dynamics during Aging | microPublication 163
Reposted by Buck Samuel 🪱🦠🧬🔬Genetics Society of America @genetics-gsa.bsky.social · 01/05/2026What is the mutation rate in natural vs laboratory populations? What are the typical divergence times among and within species? In #GENETICS, Wei et al. analyzed the evolution of clonal #Celegans genotypes collected and sequenced in Santeuil wood, France.🪱 🔗 buff.ly/1rINY0W 0104
Buck Samuel 🪱🦠🧬🔬 @microbeminded.bsky.social · 02/05/2026Very cool study by @emilyleptich.bsky.social and @rnareylab.bsky.social showing insulin regulation of learning and memory in #Celegans! journals.plos.org/plosgenetics...journals.plos.orgINS-17 acts as a nutrient deprivation signal to mediate adult IIS-regulated associative behaviors in C. elegansAuthor summary Insulin signaling is a diverse actor that regulates many processes essential for life from growth and development, aging, cognition, among many others. However, how insulin signaling re... 0121
Reposted by Buck Samuel 🪱🦠🧬🔬Katherine Aird @airdlab.bsky.social · 02/05/2026The lab is expanding and hiring both a postdoc and staff scientist! See more on our website: airdlab.com. We study how metabolism and cell cycle states drive tumor progression, therapy response, and immune interactions. Candidates interested in mechanistic cancer biology are encouraged to apply.airdlab.comAird Lab 2147
Reposted by Buck Samuel 🪱🦠🧬🔬Tera Levin @teralevin.bsky.social · 02/05/2026Bacterial immune proteins have repeatedly evolved to become parts of eukaryotic immunity. But how? Our new preprint uncovers a recent horizontal transfer event & shows how eukaryotes co-opted a toxic bacterial immune protein 🦠🧪🧵 1/ 219791
Reposted by Buck Samuel 🪱🦠🧬🔬Dr. Mandy Joye @oceanextremes.bsky.social · 02/05/2026Must watch - the #NationalScienceFoundation is being torn down, brick by brick. Pls share widely. 078
Reposted by Buck Samuel 🪱🦠🧬🔬Nature Microbiology @natmicrobiol.nature.com · 27/03/2025OUT NOW: Inducible transposon mutagenesis identifies bacterial fitness determinants during infection in mice #microsky 🧪 www.nature.com/articles/s41...nature.comInducible transposon mutagenesis identifies bacterial fitness determinants during infection in mice - Nature MicrobiologyInducTn-seq, a method for inducible mutagenesis followed by transposon insertion site sequencing, enables temporal control of transposition to bypass population bottlenecks and enable the quantificati... 310654
Buck Samuel 🪱🦠🧬🔬 @microbeminded.bsky.social · 29/04/2026A behind the scenes look at our tiny astronauts and their microbiomes being prepped for space camp on the International Space Station! www.instagram.com/reel/DXrnBE9... #CBIOMES #SpaceBiology #NASA #microbiome #wormsinspace #Celegans 🧪 🪱 🦠 🚀instagram.comInternational Space Station on Instagram: "What can worms teach us about living in space?🪱 CBIOMES just wrapped up aboard the space station, and the results could help us improve methods to protect a...1,640 likes, 18 comments - iss on April 28, 2026: "What can worms teach us about living in space?🪱 CBIOMES just wrapped up aboard the space station, and the results could help us improve methods to p... 0216
Reposted by Buck Samuel 🪱🦠🧬🔬Vaughn Cooper @vscooper.micropopbio.org · 28/04/2026🚨Microbial genomics researchers🚨 Terrific FREE web apps from @midauthorbio.bsky.social midauthorbio.com/#freetools No coding or command line required ✅ breseq, A+ microbial variant calling ✅ SprayNPray, taxonomic profiling of metagenomes ✅ Pseudofinder 🔎 pseudogenes ✅ GToTree, phylogenomic treesmidauthorbio.comMiddle Author BioinformaticsThis website describes a start-up company that specializes in bioinformatics analysis, software development, and teaching/outreach. 11911
Reposted by Buck Samuel 🪱🦠🧬🔬Jeremy Berg @jeremymberg.bsky.social · 25/04/2026My thoughts on Director Bhattacharya's Fireside Chat at the NAM workshop (a long 🧵) Overall (1) He clarified what he said that NIH is doing with regard to improving replication. While these are concrete steps, they seem either naive or dependent of unproven technology. Time will tell. 1/30 412860
Reposted by Buck Samuel 🪱🦠🧬🔬Coleen Murphy @ctmurphy1.bsky.social · 25/04/2026Super important thread on what we are losing in the US: our whole education system 174
Reposted by Buck Samuel 🪱🦠🧬🔬Ákos T Kovács @evolvedbiofilm.bsky.social · 24/04/2026Identification of bacterial signals that modulate enteric sensory neurons to influence behavior in C. elegans -in @currentbiology.bsky.social www.cell.com/current-biol...cell.comIdentification of bacterial signals that modulate enteric sensory neurons to influence behavior in C. elegansEstrem et al. show that bacterial polysaccharides, including peptidoglycans, activate the enteric sensory neuron NSM to regulate feeding and locomotion in C. elegans, while pathogen-derived metabolite... 0167
Reposted by Buck Samuel 🪱🦠🧬🔬Joshua Weitz @joshuasweitz.bsky.social · 25/04/2026Intentionally dismantling American leadership in science, degrading agency independence, reducing programmatic capacity, slashing budgets ... all while claiming that they are advancing 'gold standard' science. It is well past time for more to enter the arena & defend scientists & institutions. 15323
Reposted by Buck Samuel 🪱🦠🧬🔬Dan Garisto @dangaristo.bsky.social · 25/04/2026Breaking: Trump has fired the membership of the National Science Board, which is oversees NSF. I have confirmed separately with multiple now-former members of NSB.democrats-science.house.govRanking Member Lofgren Reacts to Latest Trump Scheme to Undermine Science | House Committee on Science, Space and TechnologyThe House Committee on Science, Space and Technology 591055762
Reposted by Buck Samuel 🪱🦠🧬🔬Waggoner Lab @labwaggoner.bsky.social · 24/04/2026Genome editing of phylogenetically distinct bacteria using cross-species retron-mediated recombineering @natbiotech.nature.com @gladstoneinst.bsky.social www.nature.com/articles/s41... 184
Buck Samuel 🪱🦠🧬🔬 @microbeminded.bsky.social · 23/04/2026Final timepoint for #CBIOMES completed on the #ISS this week! On the video is the live view of Earth below the ISS while our #Celegans move through microfluidic chambers. On orbit operations are done, now our worms wait in stasis for their return ticket. #WormsinSpace #SpaceBiology #Microbiome 🧪 🚀 092
Reposted by Buck Samuel 🪱🦠🧬🔬Cell Host & Microbe @cp-cellhostmicrobe.bsky.social · 09/04/2026How to measure microbiome health? Commentary proposes adaptive coherence: capacity of host-microbiome systems to sustain integrated function via reorganization. Reframes health as emergent & relational, w/measurements of adaptability/functional integrity www.cell.com/cell-host-mi... 1157
Reposted by Buck Samuel 🪱🦠🧬🔬Eric Topol @erictopol.bsky.social · 20/04/2026We've known the gut-brain axis is a key underpinning of Parkinson's disease. Today, for the 1st time, a gut microbiome signature denoting risk found in healthy individuals with genetic predisposition nature.com/articles/s41...nature.comMicrobiome signature of Parkinson’s disease in healthy and genetically at-risk individuals - Nature MedicineMicrobiome analysis suggests that gut microbial changes in Parkinson’s disease evolve progressively from healthy individuals to genetically at-risk individuals to clinically affected patients, with th... 519556
Reposted by Buck Samuel 🪱🦠🧬🔬Cameron Thrash @jcamthrash.bsky.social · 17/04/2026Nutrient availability shapes the diversity and structure of microbial communities www.biorxiv.org/content/10.6... #jcampubs 0103
Reposted by Buck Samuel 🪱🦠🧬🔬Sandhya Koushika @wormlockholmes.bsky.social · 18/04/2026So cool.... A landmark finding Protein-templated synthesis of dinucleotide repeat DNA by an antiphage reverse transcriptase | Science www.science.org/doi/10.1126/...science.orgProtein-templated synthesis of dinucleotide repeat DNA by an antiphage reverse transcriptaseDefense-associated reverse transcriptases (DRTs) are widespread bacterial anti-phage systems that use unconventional mechanisms of polynucleotide synthesis. We show that DRT3, which comprises two dist... 133
Reposted by Buck Samuel 🪱🦠🧬🔬PLOS Biology @plosbiology.org · 14/04/2026Some #bacteria polymerize excess carbon into polyhydroxybutyrate (PHB), a biodegradable storage polymer. This study shows that #PHB -producing bacteria kill #Celegans nematodes by disrupting pharyngeal & intestinal function @plosbiology.org 🧪 plos.io/4cFAwDz 1156
Reposted by Buck Samuel 🪱🦠🧬🔬Jordan Ward @gotworms.bsky.social · 03/04/2026Great to see this out. Practical guidance on how to use protein depletion systems in C. elegans 02312
Buck Samuel 🪱🦠🧬🔬 @microbeminded.bsky.social · 16/04/2026#WormsinSpace update: since launch day, our tiny #Celegans astronauts and their microbes have been living in microgravity. #ISS astronauts have unpacked #CBIOMES (below), and will take their first looks at these host-microbiome studies tomorrow! #microbiome #NASA #ISS #SpaceBiology 🚀 🪱 🧪 🦠 0143
Buck Samuel 🪱🦠🧬🔬 @microbeminded.bsky.social · 13/04/2026Our tiny #Celegans astronauts are 30m out from docking with the #ISS! Tune in live here plus.nasa.gov/scheduled-vi... #CBIOMES #spacebiology #microbiome #wormsinspace 🚀🧪🪱🦠 1285
Buck Samuel 🪱🦠🧬🔬 @microbeminded.bsky.social · 09/04/2026Next launch attempt of thousands of tiny astronauts on 4/11/26 at 7:40am EST! www.nasa.gov/missions/sta... #wormsinspace #microbiome #spacebiology #Celegans #CBIOMESnasa.govNASA’s Northrop Grumman CRS-24 Mission Overview - NASANASA’s Northrop Grumman Commercial Resupply Services 24 mission, or Northrop Grumman CRS-24, will deliver approximately 11,000 pounds of science and supplies to the International Space Station. This m... 174
Reposted by Buck Samuel 🪱🦠🧬🔬From the Labs at Baylor College of Medicine @bcmfromthelabs.bsky.social · 09/04/2026A #NASA-funded study on the #ISS brings together B. Samuel @microbeminded.bsky.social, S. Vanapalli and M. Driscoll to address #microgravity effects on the #gutMicrobiome and what that means on long missions. bit.ly/4clyhnP @bcmhouston.bsky.social @texastech.bsky.social @rutgersu.bsky.social 032
Reposted by Buck Samuel 🪱🦠🧬🔬Ran Blekhman @blekhman.bsky.social · 18/03/2026We're searching for the next Director of the Duchossois Family Institute at UChicago The most exciting leadership role in microbiome science right now: lead faculty, cutting-edge cores, and an FDA-approved facility for microbiome therapeutics Email/DM me if interested apply.interfolio.com/182203 368
Buck Samuel 🪱🦠🧬🔬 @microbeminded.bsky.social · 07/04/2026#Artemis is circling the Moon right now. And later this week, our team's experiment launches to the #ISS. Tiny worms. Defined gut microbiomes. Here's why the two are connected. 🧵 #WormsinSpace #CBIOMES #Celegans 🧪 🪱 🧬 🚀 1/n 33510
Buck Samuel 🪱🦠🧬🔬 @microbeminded.bsky.social · 02/04/2026#Artemis did not disappoint! Got an amazing view of the launch yesterday from NASA Kennedy Space Center. Hard to describe, but the feeling in my bones was something else and unexpected! 🚀🧪 0111
Buck Samuel 🪱🦠🧬🔬 @microbeminded.bsky.social · 01/04/2026Super excited to be at Kennedy Space Center for a #NASA project ( #wormsInSpace launching next week, but more on that later ) AND to be able to see the launch of #Artemis II! To the moon and stars!! 🚀🌖 🧪 0330
Reposted by Buck Samuel 🪱🦠🧬🔬Paul Guinnessy @paulguinnessy.bsky.social · 16/03/2026Big news from #arXiv. They are "spinning out of Cornell University and into a new independent non-profit later this year." "We are launching the search for a Chief Executive Officer to lead the new organization and ask for your help in spreading the word." #scholarlypublishing #preprints #academiajobs.chronicle.comChief Executive Officer - New York City, New York (US) job with arXiv | 37961678arXiv seeks its first CEO to champion open, free scientific discovery and guide the platform’s next chapter as an independent nonprofit. 12118
Reposted by Buck Samuel 🪱🦠🧬🔬Sarah McAnulty, Ph.D. @sarahmackattack.bsky.social · 16/03/2026Attention Science Communicators! We are conducting a survey on the landscape of science communication & need your help gathering experiences. Please send this to #SciComm ppl you know. We want to get as thorough a sense of the state of the field as we can. umiami.qualtrics.com/jfe/form/SV_... 28422466
Reposted by Buck Samuel 🪱🦠🧬🔬Javier Apfeld @javierapfeld.bsky.social · 11/02/2026We in the C. elegans community are lucky to have the #wormfeed. Big shout out to @microbeminded.bsky.social for creating such a wonderful gathering place. And you can pin the wormfeed to your homescreen: bsky.app/profile/did:... 0144
Reposted by Buck Samuel 🪱🦠🧬🔬Javier Apfeld @javierapfeld.bsky.social · 28/01/2026Friends! I am so happy to share our new preprint! Hydrogen peroxide has been the most common reactive chemical threat to life forms since the Great Oxygenation Event 2.5 billion years ago. How do animals like C. elegans sense it fast and escape? www.biorxiv.org/content/10.6... Thread 1/ 78631
Reposted by Buck Samuel 🪱🦠🧬🔬Jordan Ward @gotworms.bsky.social · 29/01/2026Excited to see this out in the world. The CGC is launching a curated strains collection, the first being protein degradation systems and this is a pilot primer to pair with it authored by myself, Dave Reiner, Ann Rougvie, and Aric Daul. We review the state of the field and provide use guidance (1) 53412
Reposted by Buck Samuel 🪱🦠🧬🔬Needhi Bhalla 💅🏽 @needhibhalla.bsky.social · 26/09/2025I signed. I was supported by a GRFP during my thesis research and its award reinforced that I was a scientist during my training. 22914
Buck Samuel 🪱🦠🧬🔬 @microbeminded.bsky.social · 26/09/2025I signed and was supported by this program as a graduate student myself. 030
Reposted by Buck Samuel 🪱🦠🧬🔬Ran Blekhman @blekhman.bsky.social · 30/08/2025More foundations should do this: "Funding is exclusively available to applicants who have already received federal funding (e.g., from the NIH, CDC, NSF) for their health equity research, but have since had their funding rescinded due to federal administrative actions" www.rwjf.org/en/grants/ac...rwjf.orgRapid Response: Reinvesting in Racial and Indigenous Health Equity ResearchThe purpose of this call for proposals is to meet the current moment by supporting timely, actionable health equity research that has been interrupted by shifts in federal funding. 78750
Reposted by Buck Samuel 🪱🦠🧬🔬Ryan Marino, MD @ryanmarino.bsky.social · 27/08/2025CDC is no longer surveilling outbreaks caused by campylobacter, cyclospora, listeria, shigella, vibrio and Yersinia. What could go wrong? 17131771304
Reposted by Buck Samuel 🪱🦠🧬🔬Needhi Bhalla 💅🏽 @needhibhalla.bsky.social · 13/08/2025This EO, combined with the retirement of Noni Byrnes at CSR/NIH, makes me very concerned about peer review at the NIH 0103