A decade of research on Pittsburgh’s Hazelwood neighborhood finds that major riverfront investment did not push out longtime residents.

A new report in the New England Journal of Medicine by researchers at Baylor College of Medicine, Texas Children’s Hospital and Seattle Children’s...

AACR and Kids Beating Cancer launched a new grant to support research aimed at improving outcomes for children with high-risk leukemia.

The white lobster, aptly named Casper, has arrived at the University of New England, where researchers are working to uncover why some lobsters develop dramatically unusual shell colors

The RAS Dialogue Blog posts are written by RAS experts sharing the latest research, updates, and scientific RAS news. The content is curated by the RAS Initiative.

The RAS Dialogue Blog posts are written by RAS experts sharing the latest research, updates, and scientific RAS news. The content is curated by the RAS Initiative.

Pathogenic variants in LZTR1 are an established cause of Noonan syndrome (NS) and uniquely exhibit both autosomal dominant (AD) and autosomal recessive (AR) inheritance. However, the phenotypic spect....

Le et al. show that in Xenopus embryos, local ectodermal tissue flows provide a directional cue that polarizes and guides embryonic myeloid cells migration via cell-on-cell interactions.

Researchers at The University of Texas MD Anderson Cancer Center have found new evidence that BRAF, a protein commonly involved in cancer, plays a key role in developing, amplifying and maintaining chronic pain caused by nerve damage.

Systematic mapping of protein-protein interaction (PPI) networks and determining how causal mutations rewire them in autism spectrum disorder (ASD) provide a powerful framework for uncovering disease ...

Concerns about myocarditis and mortality after COVID-19 vaccination in pediatrics persist despite limited direct comparisons with SARS-CoV-2 infection…

Studying a condition after being diagnosed with it can be rewarding but also presents some ethical and psychological challenges.

Blocking the kinase BRAF reduces nociceptive transmission in spinal cord after injury.

Blocking the kinase BRAF reduces nociceptive transmission in spinal cord after injury.

BACKGROUND: RASopathies constitute a group of rare genetic disorders caused by mutations in genes along the canonical RAS/mitogen-activated protein kinase (MAPK) signaling pathway, affecting cell grow...

BACKGROUND: RASopathies constitute a group of rare genetic disorders caused by mutations in genes along the canonical RAS/mitogen-activated protein kinase (MAPK) signaling pathway, affecting cell grow...

What is the most important cancer drug of 2026? Hands down, that's daraxonrasib. A first-in-class, direct inhibitor of RAS (previously thought to be impossible) that has transformed the field of panc...

What happens when you build a collaboration on the foundation of connecting population genomics, longitudinal patient follow-up, and laboratory models into one continuous loop? In this month's #RASDia...

What happens when you build a collaboration on the foundation of connecting population genomics, longitudinal patient follow-up, and laboratory models into one continuous loop? In this month's #RASDia...

Key PointsComplex mutations in KRAS predict poor outcomes in AML; complex NRAS and KRAS mutations confer an inferior prognosis in KMT2A-r AML.Noncomplex KR

Targeting RNA-binding proteins has been shown to be challenging due to the absence of druggable pockets. Recently, Lu et al. identified a molecular glue capable of degrading HuR and suppressing BRAF-m...

Cincinnati Children’s receives a $38.4 million NIH grant renewal to expand Bench to Bassinet, a national congenital heart disease genomics program.

A phase 3 randomized trial of 830 young children with severe early childhood caries found that 38% silver diamine fluoride arrested 54.0% of eligible cavitated dentin lesions at six months, compared w...