A heritable CRISPR knock-in in Schistosoma mansonigenerated a transgenic line that secreted a functional anti–SARS-CoV-2 antibody into mouse circulation. Virus neutralization by infected mouse sera de...

Mann and colleagues reveal key roles for monocytes in replenishing the subsets of uterine macrophages involved in tissue remodeling and inflammation. These processes maintain tissue homeostasis in hea...

Control of schistosomiasis, a neglected tropical disease caused by infection with Schistosoma spp., remains reliant on a single chemotherapy, prazi...

“Period of transition” at funding agency sees some Medical Research Council funding opportunities on hiatus

Global estimates of asthma prevalence are rising, with an estimated 262 million affected individuals in 2019.1 Purported reasons for this rapid rise include urbanisation of lower- and middle-income co...

Nature Communications - In schistosomiasis-endemic regions, the cyclical nature of infection and treatment complicates understanding of host immune responses. Repeated controlled human Schistosoma...

Profiling thousands of single cell transcriptomes is routine, yet cell prioritization based on response to biological perturbations is challenging and confounded by clustering, normalization and dimen...

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