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Vivien Shek

@vshek.bsky.social
101 followers 147 following 8 posts

Decoding immune responses to S. mansoni in the MacDonald lab 🪱🔬📊

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Reposted by Vivien Shek
Perona Lab, Edinburgh, UK @peronalab.bsky.social · 30/03/2026
Job opportunity for a #FlowCytometry technician, School of Biology, University of Edinburgh, UK. We do cool flow with fungi, bacteria, diatoms, space particles, as well as mammalian cells. Spectral, conventional and sorts. Join us! Details here: elxw.fa.em3.oraclecloud.com/hcmUI/Candid...
elxw.fa.em3.oraclecloud.com
Flow Cytometry Technician
We are looking for an enthusiastic person to join the flow cytometry facility in the King’s Buildings campus at the School of Biological Sciences in the University of Edinburgh. This role involves pro...
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Reposted by Vivien Shek
Henry McSorley @henrymcsorley.bsky.social · 09/03/2026
New review article published! I have rarely been prouder of a punny title. Unrelatedly, we are also pretty happy with this review - interesting area of using vaccines to block parasite immunomodulatory protein function, allowing their ejection. www.sciencedirect.com/science/arti...
sciencedirect.com
Tonic for your GIN: gastrointestinal nematode immunomodulator vaccines
No vaccines are currently available for any gastrointestinal nematode (GIN) infections of humans, despite a large global burden of disease. In livesto…
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Reposted by Vivien Shek
Edinburgh Immunology Group @edinburghimmuno.bsky.social · 13/11/2025
Please join us today for EIG mini symposium at 13:30 in IRR South seminar room 1.05 for fantastic talks on vaccines and T cells by @prof-tregoning.bsky.social @joyedwardshicks.bsky.social and @gregersj.bsky.social
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SPPIRIT Network @sppirit-network.bsky.social · 04/11/2025
Coming up: Postdoctoral fellowship mini-workshop as a part of the SPPIRIT Forum series. EMBO, Marie Curie, and Wellcome Early Career fellows will share their advice on fellowship applications. Join us at 12 noon on Thursday 14th November! Register at docs.google.com/forms/d/e/1F...
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Vivien Shek @vshek.bsky.social · 31/10/2025
Had such a great time at the ECR Research Symposium hosted by @sppirit-network.bsky.social It was fantastic to catch up with my fellow McWormers 🪱 and meet so many new faces. So nice to hear about all the exciting parasitology research happening across 🏴󠁧󠁢󠁳󠁣󠁴󠁿
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Reposted by Vivien Shek
SPPIRIT Network @sppirit-network.bsky.social · 30/09/2025
📢 Just 1 month to go until our SPPIRIT ECR symposium 📝 Abstract deadline extended to 10 October 2025 - don’t miss out!
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Vivien Shek @vshek.bsky.social · 29/09/2025
Delighted to share this story from my PhD! 🎉 🪱
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Andrew S. MacDonald @profandrewmac.bsky.social · 18/09/2025
The end of #EMDS2025 - so much amazing science, and great to meet up in person with so many friends and colleagues (and make some new ones!). Very proud of @vshek.bsky.social and @nwasowska.bsky.social winning poster prizes for the team - well done both!
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SPPIRIT Network @sppirit-network.bsky.social · 12/09/2025
📢 7 weeks to go until our SPPIRIT symposium A fantastic opportunity for ECR parasitologists across Scotland to network and showcase their research. 🗓️ 31 October 2025 | 📍 Roslin Institute, Edinburgh 🎟️ Free to attend → tinyurl.com/3yzjnm5h Secure your spot today!
tinyurl.com
Hostbusters: SPPIRITed to Roslin
Bringing together ECR parasitologists from across Scotland to network and showcase their science.
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Reposted by Vivien Shek
Dr Joanne Power @hanniepower.bsky.social · 11/09/2025
Save the dates!! @bspparasitology.bsky.social Spring Meeting 2026 will be in Bonnie Glasgow! 7-9 April 2026, with a drinks reception in Glasgow City Chambers on the 6th of April 2026! Keep an eye on the BSP website for registration and abstract submission! Logo by @shannaraeilean.bsky.social! 🦟
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Andrew S. MacDonald @profandrewmac.bsky.social · 28/07/2025
A real pleasure to be a part of this beautiful new study on T cell responses in repeat controlled human infection vs natural infection with #schistosomes, spearheaded by @emmahoulder.bsky.social with many wonderful colleagues #helminths #ImmunoSky #IDSky 🪱 🧪 www.nature.com/articles/s41...
nature.com
T cell responses in repeated controlled human schistosome infection compared to natural exposure - Nature Communications
In schistosomiasis-endemic regions, the cyclical nature of infection and treatment complicates understanding of host immune responses. Repeated controlled human Schistosoma mansoni infection, designed...
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Andrew Maclean @macleanlab.bsky.social · 23/07/2025
📣 Open postdoc position in my lab to investigate how Toxoplasma acquires nutrients. Join me at the University of Edinburgh. Closing date 14th August. More details below ⬇️ elxw.fa.em3.oraclecloud.com/hcmUI/Candid...
elxw.fa.em3.oraclecloud.com
Postdoctoral Research Associate
We are looking for a talented and enthusiastic Postdoctoral researcher to join the Maclean lab to investigate the metabolism of the human parasite Toxoplasma gondii.
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Reposted by Vivien Shek
SPPIRIT Network @sppirit-network.bsky.social · 09/07/2025
🚨 Postdoc alert! Amazing opportunity to work on Toxoplasma with @youngtoxolab.bsky.social in Edinburgh. Check it out!
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Reposted by Vivien Shek
bioRxivpreprint @biorxivpreprint.bsky.social · 31/05/2025
HpBoRB, a helminth-derived CCP domain protein which binds RELMβ www.biorxiv.org/content/10.1101/202…
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Keith Matthews @keithrmatthews.bsky.social · 16/05/2025
Please consider applying for a post doc in our lab if you have bioinformatics and wet lab skills, and are interested in parasites! elxw.fa.em3.oraclecloud.com/hcmUI/Candid...
elxw.fa.em3.oraclecloud.com
Postdoctoral Research Associate
This project will seek to understand the basis of increased virulence after long term coinfection by a combination of genomic, transcriptomic and laboratory manipulation of the selected parasite lines...
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Reposted by Vivien Shek
Matt Higgins @parasitematt.bsky.social · 03/06/2025
Looking for a fully-funded D. Phil. / Ph.D. studentship in structural biology and vaccinology? Come to join our team. Fully and generously funded by a donation from the Kyner-Field family with full fees at overseas level. Join us! www.bioch.ox.ac.uk/studentships
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Vivien Shek @vshek.bsky.social · 23/05/2025
💉🐭🪱
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Reposted by Vivien Shek
Cell Reports @cp-cellreports.bsky.social · 22/05/2025
Vaccination against helminth IL-33 modulators permits immune-mediated parasite ejection
dlvr.it
Vaccination against helminth IL-33 modulators permits immune-mediated parasite ejection
The helminth immunomodulators from the HpARI and HpBARI families can block IL-33 responses. Smyth and Hodge et al. show that vaccination with these immunomodulatory proteins can raise blocking antibody responses against them, allowing the development of effective anti-parasite type 2 immunity and ejection of the parasite.
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emds2025.bsky.social @emds2025.bsky.social · 30/04/2025
🚨 REGISTRATION NOW OPEN!!! Head to www.emds2025.com to register and submit your abstracts. Full programme is now available. NB: Spaces are limited, so don't delay, register today! @britsocimm.bsky.social @efis-immunology.bsky.social @societymucosalimm.bsky.social @natrevimmunol.nature.com
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Edinburgh Immunology Group @edinburghimmuno.bsky.social · 28/04/2025
The spring EIG session is coming this Thursday on 1st of May. Please join us from 13:30 in @edinuni-irr.bsky.social IRR South seminar room 1.05 for fantastic talks by Dr. Elizabeth Mann, Dr. Tovah Shaw and Prof. Hamida Hammad. See you there!
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amyhbuck.bsky.social @amyhbuck.bsky.social · 02/04/2025
Very excited to share this collaborative work led by Kyriaki Neophytou. An extracellular Argonaute from a nematode parasite is transmitted to host cells and the non-vesicular form is functionally important (and now a vaccine candidate). An Argonaute vaccine... who would have thought.
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Reposted by Vivien Shek
emds2025.bsky.social @emds2025.bsky.social · 19/03/2025
Welcome to the BSky account for EMDS2025. Please follow us to hear about updates & deadlines for EMDS2025: Scotland Edition. Check out www.emds2025.com for full details - registration will open soon. We look forward to welcoming you all to the wonderful city of Edinburgh in September.
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Vivien Shek @vshek.bsky.social · 17/03/2025
Excited to start this next chapter in the @profandrewmac.bsky.social Lab! I’ll be exploring how Schistosoma mansoni shapes immune responses in the gut. Looking forward to new discoveries, collaborations, and plenty of worm talk! 🪱🐌🔬
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Andrew S. MacDonald @profandrewmac.bsky.social · 14/03/2025
Join us in Edinburgh in September for the 38th European #Macrophage and #DendriticCell Society meeting! We have a great lineup of speakers and are looking forward to all the fantastic talks and interactions that make this meeting special. #EMDS #ImmunoSky 🧪🏴󠁧󠁢󠁳󠁣󠁴󠁿🔬 www.emds2025.com
emds2025.com
EMDS 2025. Online registration by Cvent
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Reposted by Vivien Shek
Perona Lab, Edinburgh, UK @peronalab.bsky.social · 03/03/2025
I'm very pleased to have two lab positions open this week, to join our team looking at immune regulation in infection and co-infection. We're especially interested in tissue-based immunity, cytokine regulation and immune metabolism. Join us! Postdoc (3y) and research technician (12mo) posts open.
We're based in the Ashworth Laboratories, King's Buildings, University of Edinburgh. Photo shows the main staircase in the entrance to the Ashworth, stone steps from the 1920s, decorated with a series of bright, colurful banners depicting the science that's tackled in the building.
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Perona Lab, Edinburgh, UK @peronalab.bsky.social · 24/02/2025
Our search for a flow cytometry core facility manager for King's Buildings, University of Edinburgh, is finally live. Join us! Conventional & spectral. Parasites, immune cells, algae, bacteria, yeast and more. Full-time, open-ended. Apply by 17 March. elxw.fa.em3.oraclecloud.com/hcmUI/Candid...
elxw.fa.em3.oraclecloud.com
Flow Facility Manager
We are looking for a facility manager for the SBS flow cytometry core facility. This is a full-time position (35 hours per week) with most of that time expected to be on campus in the flow facility. W...
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Reposted by Vivien Shek
Henry McSorley @henrymcsorley.bsky.social · 13/12/2024
Christmas biscuits from the lab!! I must get a new red check shirt…
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Henry McSorley @henrymcsorley.bsky.social · 12/12/2024
PhD available in the excellent @peronalab.bsky.social of Georgia Perona-Wright. The only downside of the PhD for the student is that I will also be involved. Its a cool project and will be a fun collaboration!
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Henry McSorley @henrymcsorley.bsky.social · 20/11/2024
Congratulations @vshek.bsky.social ! First PhD from the Dundee Mcsorley lab, second one will be coming from Nicole (left) very soon hopefully!
Vivien Shek, her PhD thesis, and Nicole. It is very cold today!
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Vivien Shek @vshek.bsky.social · 20/11/2024
After submitting my thesis and defending it in August, the reality of it all didn’t quite hit—until now! Holding a hardcopy of my thesis in hand and walking across the stage at graduation, it truly feels like the end of an era.
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Henry McSorley @henrymcsorley.bsky.social · 08/11/2024
After a fairly rotten week, some welcome news - our latest paper has been accepted at eLife. In it, we show that members of the HpARI family either bind (HpARI1 and HpARI2) or do not bind (HpARI3) to heparan sulphate. This binding controls their in vivo half-life. elifesciences.org/articles/99000
elifesciences.org
Heparan sulphate binding controls in vivo half-life of the HpARI protein family
The HpARI family members can either suppress or amplify responses to IL-33, and also differ in their half-life in vivo due to binding to the extracellular matrix constituent, heparan sulphate.
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Reposted by Vivien Shek
bioRxiv Immunology @biorxiv-immuno.bsky.social · 23/08/2024
Vaccination against helminth IL-33-modulators permits immune-mediated parasite ejection www.biorxiv.org/content/10.1101/202…
biorxiv.org
Vaccination against helminth IL-33-modulators permits immune-mediated parasite ejection https://www.biorxiv.org/content/10.1101/2024.08.22.609138v1
The murine intestinal nematode Heligmosomoides polygyrus bakeri powerfully modulates the host immune
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Vivien Shek @vshek.bsky.social · 16/04/2024
Final PhD experiment done, marking the end of my lab work! I'm due to finish writing by July and would be grateful if you could keep me in mind for future postdocs in immunoparasitology, mucosal immunology and host-pathogen interactions 👩🏻‍🔬🪱🫁
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