We are pleased to announce seven exciting postgraduate opportunities within the Cancer Research UK Manchester Institute for new PhD Students to start in 2026

This study uncovers a surprising role for GCs in triggering CD8+ T cell–dependent tumour control through downregulation of GARP and thus TGF β signalling.

The intestinal immune system must concomitantly tolerate food and commensals and protect against pathogens. Antigen-presenting cells (APCs) orchestrate these immune responses by presenting luminal ant...

Cyclooxygenase-driven prostaglandin E2, produced by a variety of tumors, drives malignant growth through successful evasion of type I interferon and/or T-cell-dependent tumor elimination. A remarkable synergy between cyclooxygenase inhibitors and checkpoint blockade immunotherapy results in tumor eradication.

Inflammation can fuel or suppress cancer. Bonavita et al. identify NK cells as primary orchestrators of T cell inflammation in murine models and devise an inflammatory signature that predicts patient survival and response to immunotherapy in multiple malignancies.

bioRxiv - the preprint server for biology, operated by Cold Spring Harbor Laboratory, a research and educational institution

The Lung Cancer Centre of Excellence will continue its groundbreaking research with up to £4m of funding support from ScottishPower.