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Emma Houlder

@emmahoulder.bsky.social
54 followers 62 following 10 posts

Researcher at LUMC. Immunology, schistosomiasis, vaccines.

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Emma Houlder @emmahoulder.bsky.social · 31/07/2025
In schistosome 🪱-endemic areas, people are repeatedly reinfected — but we still don’t fully understand how T cell responses develop in these cycles. In my first ever last-author paper (😱) we investigate this, comparing endemic and repeat controlled human schistosome infection: rdcu.be/exH58
rdcu.be
T cell responses in repeated controlled human schistosome infection compared to natural exposure
Nature Communications - In schistosomiasis-endemic regions, the cyclical nature of infection and treatment complicates understanding of host immune responses. Repeated controlled human Schistosoma...
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Emma Houlder @emmahoulder.bsky.social · 12/06/2025
[1/7] How close are we to a schistosomiasis vaccine? With help from an #MSCA fellowship and support from Batavia Biosciences, I spent 6 months reviewing 100+ pre-clinical studies on S. mansoni vaccines. Here's what we found: 📄 doi.org/10.1371/jour...
doi.org
Pre-clinical studies of Schistosoma mansoni vaccines: A scoping review
Author summary Schistosomiasis, a major neglected tropical disease, is caused by infection with parasitic worms of the Schistosoma species, including Schistosoma mansoni. Individuals can be repeatedly...
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Emma Houlder @emmahoulder.bsky.social · 20/12/2024
FIRST POST! Fungi drive asthma, but does this require germination? We show A. fumigatus spores activate DCs after 3hrs of swelling, promoting airway allergy. Antifungal itraconazole limits swelling & reduces allergic inflammation. Check it out: doi.org/10.1016/j.ja... @drpetercook.bsky.social 👩‍🔬
Airways, inflamed on left after 4hr spores and less inflamed on right with 4hr spores and itraconazole treatment.
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Reposted by Emma Houlder
Peter Cook @drpetercook.bsky.social · 25/11/2024
First 🦋 post (great to join everyone here) about our paper that's been published in JACI: www.jacionline.org/article/S009... Check it out if you have ever wondered how fungal spore growth controls how dendritic cells (clearly THE best immune cell) trigger inflammation that causes asthma...
jacionline.org
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