Bacterial spores are among the most durable of cell forms, protected by robust envelopes of layered protein assemblies. Remarkably, these envelopes often share similar architectures across distantly r...

New analysis refutes James Watson’s claim he was first to recognize significance of famed photograph 51

From pursuing an impossible dream to uncovering one of the cell’s best-kept secrets and advancing the design of improved antibiotics

Clostridioides difficile is a major cause of antibiotic-associated diarrhea. This pathogen produces toxins essential for disease and flagella that promote intestinal colonization. Flagella and toxins ...

Greenland Energy oil drilling in Jameson Land is blocked for 2026: Greenland’s mineral official confirmed the Trump-linked NASDAQ firm cannot receive permits before November 8, past the logistics wind...

Cell-cell signaling using a core metabolite repurposed as a developmental cue coordinates bacterial multicellular development.

Two new labs will back British researchers to develop next generation artificial intelligence (AI) systems, helping secure the UK’s position as a global leader.

Successful infection by a bacteriophage requires the injection of the phage genome into the cytoplasm of the host bacterium. To achieve this, an infec…

Identification of CprV during bacterial sporulation reveals insight into how developing cells monitor compartmental integrity during cellular remodelling and differentiation.

Following an extended period of declining prevalence of the epidemic Clostridioides difficile ribotype 027 (RT027) in Portugal, a genetically distinct, multidrug-resistant (MDR) RT027 strain with r...

Exclusive: Science department approves UKRI’s cost-saving proposal, with major UK facilities also facing cutbacks

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Clostridioides difficile is an urgent threat to human health. Current treatments for C. difficile infections (CDIs) are antibiotics and microbiome restoration therapy (MRT) for recurrent cases. Howeve...

Two recent cryogenic electron microscopy (cryoEM) structures provide a unique opportunity to compare a bacteriophage and a bacteriocin targeted at the same host. CryoEM reveals the most detailed view ...

The Novo Nordisk Foundation Center for Protein Design at the University of Copenhagen seeks to appoint two new group leaders in de novo protein design from 1 February 2027 or as soon as possible thereafter. These positions will be at the Assistant or Associate Professor level and associated with the Department of Biology (Faculty of Science) or the Department of Drug Design and Pharmacology (Faculty of Health and Medical Sciences).

The University of Sheffield has risen 10 places in the QS World University Rankings 2027 to be ranked 82nd in the world and 14th in the UK, reinforcing its position as a world-leading university

Nature - Organisms called bathynomids boast a bacterial gene that helps them to regulate their metabolism in the cold depths.

Scientists have long worried about the reliability of commercial antibodies, and the latest findings have sparked fresh concerns.

Even with federal grants largely restored, scientists say the Trump administration is still preventing those funds from reaching them. The consequences, they say, are already becoming clear.

In a new report, the Education Committee said 24 institutions are at risk of insolvency and closure within 12 months

The preprint server is the latest to impose stiff penalties on authors who contribute to AI ‘slop’ — but not everyone is convinced it’s the right approach.

Prophages are pervasive in the human gut yet largely overlooked in microbiome research, despite substantial functional potential. Emerging evidence indicates that prophages regulate bacterial fitness,...

Browser-based prophage prediction using PhiSpy, Pyodide, and WebAssembly

Searching for an academic job? Explore this Assistant Technical Specialist opening on jobs.ac.uk! Click to view more details and browse other academic jobs.

The open access movement was bold and promising, but ultimately disappointing. Now is the time to stop and call for a new way to make publishing work…

Nature Methods - ROCKET improves experimental structure elucidation by integrating implicit structural knowledge from OpenFold, a trainable reimplementation of AlphaFold2, with X-ray...

The Department of Biology conducts research and teaching in many subject areas such as ecology, evolutionary biology, organismal biology and molecular biology. A total of approximately 300 people curr

Scientists from the University of Manchester have played a leading role in the discovery of a new subatomic particle at CERN's Large Hadron Collider (LHC). The particle, known as the Ξcc⁺ (Xi‑cc‑plus)...

The Clostridia are a phylogenetically diverse group of anaerobic, spore-forming bacteria that include species of medical, veterinary and industrial importance. The last two decades have seen major adv...