From pursuing an impossible dream to uncovering one of the cell’s best-kept secrets and advancing the design of improved antibiotics

Successful infection by a bacteriophage requires the injection of the phage genome into the cytoplasm of the host bacterium. To achieve this, an infec…

Two recent cryogenic electron microscopy (cryoEM) structures provide a unique opportunity to compare a bacteriophage and a bacteriocin targeted at the same host. CryoEM reveals the most detailed view ...

Boards asked to recommend just three applications for funding, as BBSRC also suspends calls

Here, the authors show that packaging of bacterial DNA by phage-like particles is widespread in the gut microbiome, with activity of gene transfer agents being prominent in Oscillospiraceae and Rumino...

Here, the authors show that packaging of bacterial DNA by phage-like particles is widespread in the gut microbiome, with activity of gene transfer agents being prominent in Oscillospiraceae and Rumino...

We are pleased to present a special collection of cell biology research that most captivated readers of LSA over the past year. These articles offer exciting new perspectives on how cells carry out ba...

Abstract. Plasmodium falciparum is a eukaryotic pathogen responsible for the majority of malaria-related fatalities. Plasmodium belongs to the phylum Apico

Abstract. Plasmodium falciparum is a eukaryotic pathogen responsible for the majority of malaria-related fatalities. Plasmodium belongs to the phylum Apico

The cryo-EM structure of phage φTE is presented, revealing a distinct neck topology, tail sheath baseplate organization and oligomeric state of the tape measure protein. These features suggest a mecha...

New insights into a ‘friendly virus’ that could pave the way for cutting edge treatments for the potentially fatal superbug C.diff have been uncovered by University of Sheffield scientists.

The molecular details of phage tail contraction and bacterial cell envelope penetration remain poorly understood and are completely unknown for phages infecting bacteria enveloped by proteinaceous S-l...

Here, we present a novel approach to study packaging and mobilisation of bacterial DNA in complex microbial communities, such as the human gut microbiome, by viral or virus-like capsids. Transducing b...