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Miguel Paredes

@paredesmig.bsky.social
515 followers 342 following 14 posts

Working on Genomic Epidemiology & Phylodynamics. MD-PhD student at the University of Washington/Fred Hutch Cancer Center. He/him/él 🇨🇴🏳️‍🌈

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Reposted by Miguel Paredes
Yonatan Grad @yhgrad.bsky.social · 04/09/2026
Postdoc position in infectious disease epi, genomics, applied stats to join our work on sampling strategies for pathogen genomics surveillance. Based in Shirlee Wohl’s group at BWH but to work closely with my team. See ad here: massgeneralbrigham.wd1.myworkdayjobs.com/en-US/MGBExt...
massgeneralbrigham.wd1.myworkdayjobs.com
Postdoctoral Fellow
Site: The Brigham and Women's Hospital, Inc. Mass General Brigham relies on a wide range of professionals, including doctors, nurses, business people, tech experts, researchers, and systems analysts t...
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Miguel Paredes @paredesmig.bsky.social · 24/08/2026
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Miguel Paredes @paredesmig.bsky.social · 22/08/2026
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Miguel Paredes @paredesmig.bsky.social · 31/07/2026
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Miguel Paredes @paredesmig.bsky.social · 29/07/2026
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Reposted by Miguel Paredes
BK. Titanji @boghuma.bsky.social · 09/07/2026
Meningococcal B vaccine ddi not prevent Gonorrhea in this RCT. It is a negative result but an important one which emphasizes the need for N. gonorrhoeae specific vaccines. We are seeing higher rates on gonococcal infections and more drug resistance globally. www.nejm.org/doi/full/10....
nejm.org
Meningococcal B Vaccine to Prevent Neisseria gonorrhoeae Infection | NEJM
No vaccines are currently licensed for the prevention of Neisseria gonorrhoeae infection. Observational studies suggest that the four-component meningococcal serogroup B vaccine (4CMenB) may reduce...
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public health guy @publichealthguy1.bsky.social · 12/06/2026
appreciate @stephanienolen.bsky.social and @carlzimmer.com ending the article with this important history on ebola drug access
In 2019, during an Ebola outbreak in Congo, a trial funded largely by the U.S. National Institutes of Health tested four monoclonal antibodies treatments. Two of the drugs cut deaths in patients by as much as 50 percent. One of them was developed from the blood of a Congolese Ebola survivor.
And yet, despite the public funding and the local origin of the treatments, there was no guarantee that the promising drugs would be supplied in Congo. Two companies, Regeneron and Ridgeback Biotherapeutics, ended up holding the intellectual property. Neither registered either drug in any of the countries where Ebola outbreaks occur.
Instead, the U.S. government bought the entire supply of both drugs for its own national security stockpile.
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Ursula Hofer @hoferu.bsky.social · 04/06/2026
Look at that -- an mpox mRNA vaccine!! Tapping the sign, could we please have funding and appropriate regulation for mRNA vaccines back?
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Kristian G. Andersen @kgandersen.bsky.social · 18/05/2026
Amazing speed from the teams in Uganda and the DRC - impressive! Three genomes released so far - a few quick takes: 1️⃣ New genomes ~equidistant from 2007 and 2012 outbreaks. 2️⃣ Represents new spillover from reservoir. 3️⃣ Limited diversity, so too early to speculate on timing. Great work ⭐!
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BK. Titanji @boghuma.bsky.social · 13/05/2026
A new Lancet study just reported the primary mortality analysis from the RTS,S malaria vaccine implementation programme in Ghana, Kenya, and Malawi. The verdict after 46 months is 1 in 8 deaths averted in eligible children, a very important outcome. www.thelancet.com/journals/lan...
thelancet.com
Impact of introducing RTS,S/AS01E malaria vaccine on mortality in young children in Ghana, Kenya, and Malawi: an observational evaluation of a cluster-randomised implementation programme
Introduction of the RTS,S malaria vaccine in routine immunisation programmes was associated with a significant reduction in mortality in young children, averting about one in eight deaths, in areas wi...
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Marc Veldhoen @marcveld.bsky.social · 08/05/2026
The Andes variant has been sequenced and publically shared. I leave it to virologists to dissect this first. virological.org/t/co... 1/2
virological.org
Complete sequence of Orthohantavirus andesense virus: Swiss resident 2026
Posted on behalf of the Swiss National Reference Center for Emerging Viral Infections, Geneva University Hospitals and the Institute of Medical Virology, University of Zurich (Partner Laboratory National Reference Center for Emerging Viral Infections). On 5 May 2026, the Swiss National Reference Center for Emerging Viral Infections (Geneva University Hospitals) confirmed a case of Andes strain in a Swiss resident who had travelled on the MV Hondius cruise ship. The virus was sequenced from bloo...
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Vittoria Colizza @vcolizza.bsky.social · 21/04/2026
What we choose to implement - and when - matters. Our work shows that proactive screening strategies can reduce transmission by ~40% vs reactive responses. A key lesson for preparedness. In PNAS Nexus: ow.ly/cLnu50YCrcn
ow.ly
Proactive vs. reactive COVID-19 screening in schools: Lessons from experimental protocols in France during the Delta and Omicron waves
Abstract. The COVID-19 pandemic prompted diverse policies to manage safety in schools, balancing transmission control with educational continuity. We evalu
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University of Washington School of Medicine @uwsom-wwami.bsky.social · 15/04/2026
Congratulations to Miguel Paredes, Ph.D. Epidemiology; M.D. Medicine, on being named to the 2026 Husky 100. His work on infectious disease spread, health equity and community-centered care reflects the very best of UW. #Husky100 bit.ly/4vyFDwL
Miguel Parades posing for the camera with a smile; against a purple background and Husky 100 logo.
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Miguel Paredes @paredesmig.bsky.social · 21/04/2026
Honored to be a part of the #Husky100 this year!
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Apoorva Mandavilli @apoorvanyt.bsky.social · 01/04/2026
The CDC has paused testing for rabies and pox viruses, the family of viruses that includes smallpox and mpox — and by July will have no experts to advise states on clinical aspects of the diseases Gift link: www.nytimes.com/2026/04/01/h...
nytimes.com
C.D.C. Pauses Testing for Rabies and Mpox
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Cécile Tran Kiem @ceciletk.bsky.social · 19/03/2026
Excited to share our work w/ @justinlessler.bsky.social, Trevor Bedford & Amanda Perofsky: doi.org/10.1098/rspb.... We investigate when sequence datasets are informative about between-group transmission, and how this depends on the relative pace of mutation, between-group transmission and sampling.
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Apoorva Mandavilli @apoorvanyt.bsky.social · 11/03/2026
Pediatricians contending with a sharp rise in vaccine hesitancy are trying to stay sensitive and supportive, even as they bear the brunt of parents’ mistrust and confusion. Gift link: www.nytimes.com/2026/03/11/h...
nytimes.com
In Talking to Parents About Vaccines, Pediatricians Navigate a Sea of Misinformation
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The Lancet @thelancet.com · 27/02/2026
On the cover of The Lancet: Editorial — “Robert F Kennedy Jr: 1 year of failure” Read the latest issue: spkl.io/63327Aa31W
Cover of The Lancet, 28 February 2026 issue. The quote: “The destruction that Kennedy has wrought in 1 year might take generations to repair, and there is little hope for US health and science while he remains at the helm.”
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BK. Titanji @boghuma.bsky.social · 25/02/2026
The full results of the STOMP trial are now published in @nejm.org Tecovirimat did not shorten time to symptom resolution or impact symptoms of clade II mpox. The findings are similar to PALM007 trial which found no beneficial effects of the drug for clade I mpox www.nejm.org/doi/full/10....
nejm.org
Tecovirimat for the Treatment of Mpox | NEJM
Tecovirimat is approved for smallpox treatment under the Food and Drug Administration Animal Rule on the basis of efficacy in nonhuman primate models of mpox (previously known as monkeypox). Howeve...
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BK. Titanji @boghuma.bsky.social · 24/02/2026
Brilliant plenary on STI trends at #CROI2026. DoxyPEP implementation in Seattle shows indirect reductions of syphilis rates in cisgender women who are not the target group for the intervention. Shared sexual networks with men who are the target intervention group?
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The Ferrari Lab @theferrarilab.bsky.social · 22/02/2026
I use this (overly simplified) schematic to explain to folks why maintaining high measles immunity is so hard. Even with 100% coverage, you get different outcomes depending on who and when you vaccinate. Consider a population with more kids than adults -- start with them all being susceptible.
graph with age on the x-axis and population size on the y-axis. A curve indicates population size decreasing with age. It is shaded in orange under the curve.
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Thelonevirologist @thelonevirologist.bsky.social · 21/02/2026
COVID-19 vaccination status during pregnancy and preeclampsia risk: the pandemic-era cohort of the INTERCOVID consortium www.thelancet.com/journals/ecl...
thelancet.com
COVID-19 vaccination status during pregnancy and preeclampsia risk: the pandemic-era cohort of the INTERCOVID consortium
COVID-19 vaccination with a booster reduces the odds of PE by 30% approaching 60% reduction among women with pre-existing morbidities.
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Michael Marks @drmichaelmarks.bsky.social · 18/02/2026
Our Cutaneous Leishmaniasis cohort study in Ethiopia now out. Most patients received Sodium Stibogluconate but we show this has an extremely low cure rates at end of treatment. This data underpins our @globalhealthedctp3.bsky.social Multi-Arms-Multi-Stage trial to improve CL treatment.
academic.oup.com
Clinical and patient-reported outcomes of cutaneous leishmaniasis treatment in Ethiopia: A prospective, observational cohort study in two referral hospitals
We ran a prospective cohort of patients with cutaneous leishmaniasis patients in Ethiopia. Regardless of treatment choice we observed poor cure rates at 90
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Anna Holmes @annabookwriter.bsky.social · 13/02/2026
Oh my GOD King County Public Health is just wilding out for Valentines Day (and a lovely one).
A valentine from Public Health of Seattle and King County. A man shivers in bed while a smiling lady in a red mask shows off her bandage on her arm.

Text: Noses are red
Ice packs are blue
I'm vaxed so miss me with severe symptoms of flu.A valentine from Public Health of Seattle and King County. Two lady scientists shrug lackadaisically. Text reads: My love for you can't be explained by science. Just like the new federal vaccine guidelines.A valentine from Public Health of Seattle and King County. Protesters in Minneapolis wear thick clothes and hold signs of support for immigrant neighbors. Text reads: To the health departments in the Twin Cities:
Love unites us.
Our hearts are with you.
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Ian M. Mackay, PhD (he/him) 🦠🤧🧬📑🦟🧀 @mackayim.bsky.social · 14/02/2026
#Mpox: recombinant virus with genomic elements of clades Ib and IIb - Global www.who.int/emergencies/...
who.int
Mpox: recombinant virus with genomic elements of clades Ib and IIb – Global situation
Recombination of monkeypox virus (MPXV) strains has been documented in recent months, with two cases of a recombinant strain comprising clade Ib and IIb MPXV reported. Recombination is a known natur...
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Eric Topol @erictopol.bsky.social · 06/02/2026
The real story about statin safety from >122,000 RCT participants with individual level data. They can cause new-onset diabetes and muscle pain/weakness, but other than that they are remarkably safe for 62 outcomes. Rare liver function test abnormalities thelancet.com/journals/lan...
thelancet.com
Assessment of adverse effects attributed to statin therapy in product labels: a meta-analysis of double-blind randomised controlled trials
Adverse event data from blinded randomised trials do not support causal relationships between statin therapy and most of the conditions (including cognitive impairment, depression, sleep disturbance, ...
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Kathleen Bachynski @bachynski.bsky.social · 06/02/2026
“What we found is there’s no significant excess risk with statins for almost all the conditions listed in statin packaging as potential side effects… We now have really good evidence that although these things may well happen to people while they take statins, that statins are not the cause”
statnews.com
Statins don’t cause most of the side effects on package warnings, study finds
Many people who should be taking statins avoid them for fear of side effects. A large new study says most of those side effects don't actually show up.
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Kathleen Bachynski @bachynski.bsky.social · 06/02/2026
Oh boy. “The University of Florida and the Florida Department of Health in Alachua County are investigating potential measles exposure in two UF classes following two confirmed cases in the county. Health officials have begun contacting individuals who may have been exposed.” @aetiology.bsky.social
news4jax.com
Measles exposure reported in two University of Florida classes, university says
The University of Florida and the Florida Department of Health in Alachua County are investigating potential measles exposure in two UF classes following two confirmed cases in the county.
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UW Infectious Disease Fellowship Program @uwidfellowship.bsky.social · 19/01/2026
Mpox cohorts from NYC and Houston. Conclusion: Post-mpox sequelae frequently persisted 11 to 18 months after acute mpox, with limited body distribution or physical morbidity but with continued social and sexual effects. www.acpjournals.org/doi/10.7326/... #IDSky
acpjournals.org
Long-Term Mpox Sequelae 11 to 18 Months After Acute Illness: A Cohort Study in Two U.S. Cities: Annals of Internal Medicine: Vol 0, No 0
Background: Little was known about persistent sequelae of mpox before the 2022 multinational clade II mpox virus outbreak. Objective: To characterize post-mpox sequelae 11 to 18 months after acute mpo...
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UW Infectious Disease Fellowship Program @uwidfellowship.bsky.social · 13/01/2026
The NIRSE-GAL study looking at real world impact of nirsevimab in infants in Spain. Of 12 492 eligible infants, 94·4% received immunization. RSV-related LRTI hospitalisations decreased by 85·9% in the 1st season and 55·3% in the 2nd. www.thelancet.com/journals/lan... #IDSky
thelancet.com
Impact of universal nirsevimab prophylaxis in infants on hospital and primary care outcomes across two respiratory syncytial virus seasons in Galicia, Spain (NIRSE-GAL): a population-based prospective...
Universal infant nirsevimab prophylaxis markedly reduced RSV-related hospitalisations and outpatient morbidity, with sustained reductions in RSV-related LRTI hospitalisations into the second season an...
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Deb Houry @drdebhoury.bsky.social · 10/01/2026
20 out of 25 CIO director positions at CDC are vacant and filled by actings (or eliminated), just in the past year via CDC Data Project www.cdcdataproject.org/leadership-c...
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Miguel Paredes @paredesmig.bsky.social · 05/01/2026
Sharing this personal Op-Ed again given the abrupt and unjustified changes to the childhood vax schedule (www.statnews.com/2026/01/05/c...). The schedule protects not only the kiddos but their family and community too. The schedule should be guided by impartial evidence, not blatant political gain
statnews.com
Federal health officials slash recommended childhood vaccinations under Trump’s directive
The number of recommended childhood shots drops from 17 to 11.
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Colin Carlson @colincarlson.bsky.social · 04/01/2026
Talking with my colleagues from around the world and thinking, as I do often these days, about this quote from my colleague @gregggonsalves.bsky.social, which articulated something that I think many of us know but is rarely said with this clarity. www.thenation.com/article/acti...
The challenge to those of us in public health is not just to speak out but to be active proponents of nonviolence and peacemaking. This means taking an abolitionist view of sorts, in which we work toward a world in which violence is a thing of the past. I am not naïve enough to think that this is an achievable goal right now, but that must be our ultimate aim, or we will remain complicit in some way.
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UW Infectious Disease Fellowship Program @uwidfellowship.bsky.social · 11/12/2025
www.cdc.gov/mmwr/volumes... #IDSky #COVID #vaccines
cdc.gov
Effectiveness of 2024–2025 COVID-19 Vaccines in Children...
This report describes COVID-19 vaccine effectiveness among children ages 9 months to 17 years.
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UW Infectious Disease Fellowship Program @uwidfellowship.bsky.social · 09/12/2025
In this analysis of clinical surveillance data, the median incubation period from exposure to rash was 13.6 days. Sexual transmission had a shorter median (10.3 days [CrI, 3.1 to 20.3 days]) than nonsexual transmission (13.5 days [CrI, 9.5 to 19.1 days]). www.acpjournals.org/doi/10.7326/...
acpjournals.org
The Incubation Periods of Mpox Virus Clade Ib | Annals of Internal Medicine
Background: Mpox virus (MPXV) clade Ib, first detected in the Democratic Republic of the Congo (DRC) in September 2023, spread internationally within months, prompting an emergency declaration from th...
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BK. Titanji @boghuma.bsky.social · 08/12/2025
A recombinant strain of mpox virus has been isolated from a patient in the UK containing fragments of clade I and clade II virus. Recombination occurs when two strains of virus infect a cell. These events tend to be rare but are well described in poxviruses. www.theguardian.com/world/2025/d...
theguardian.com
England health officials identify newly evolved variant of mpox
Virus caught by person who travelled to Asia combines more severe form of mpox with less virulent type
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NEJM.org @nejm.org · 03/12/2025
In a new trial, one dose of an HPV vaccine was noninferior to two doses in preventing HPV type 16 or 18 infection. Full ESCUDDO trial results: nej.md/49OEzg1 Editorial: Evidence to Action — Single-Dose HPV Vaccination and Cervical HPV Infection nej.md/3XsH9Rx #MedSky #IDSky
A diagram of the enrollment, randomization, and follow-up.
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The American Academy of Pediatrics @ameracadpeds.bsky.social · 02/12/2025
Because of the hepatitis B birth dose and completion of the infant series of the vaccine, the U.S. has made significant progress in reducing chronic hepatitis B. Eliminating the birth dose would reverse this progress and put children's health at risk. Read more: www.aap.org/en/news-room...
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The American Academy of Pediatrics @ameracadpeds.bsky.social · 20/11/2025
“Since 1998, independent researchers have conducted more than 40 high-quality studies involving over 5.6 million people. The conclusion is clear and unambiguous: There’s no link between vaccines and autism." -Dr. Susan Kressly, AAP President on recent changes to the CDC's website
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Megan Ranney MD MPH @meganranney.bsky.social · 17/11/2025
New paper reminds us yet again: HOMICIDE is the leading cause of death for pregnant women. Gun violence & partner violence are related. All-cause homicide & firearm homicide of pregnant women are higher, in states w/ higher calculated firearm ownership (1/x 🧵 jamanetwork.com/journals/jam...
jamanetwork.com
Firearm Homicide in Pregnant Women and State-Level Firearm Ownership
This cross-sectional study examines firearm homicide rates in pregnant compared with nonpregnant women and whether estimated state-level firearm ownership is associated with homicide deaths among preg...
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Louise H. Moncla @lhmoncla.bsky.social · 12/11/2025
Our lab's paper describing the North American H5N1 epizootic is out now in Nature! So thrilled to have this out, and congratulations to @lambod50.bsky.social for all the fantastic work on this: www.nature.com/articles/s41...
nature.com
Ecology and spread of the North American H5N1 epizootic - Nature
The panzootic of highly pathogenic H5N1 since 2021 was driven by around nine introductions into the Atlantic and Pacific flyways, followed by rapid dissemination through wild migratory birds, primaril...
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BK. Titanji @boghuma.bsky.social · 09/11/2025
A fascinating new Lancet ID paper offers the strongest comparative evidence yet between infection-induced and vaccine-induced immunity against mpox. The study followed people for up to 2 years after infection with monkeypox virus or vaccination with MVA-BN. #IDsky www.thelancet.com/journals/lan...
thelancet.com
Long-term consequences of monkeypox virus infection or modified vaccinia virus Ankara vaccination in Belgium (MPX-COHORT and POQS-FU-PLUS): a 24-month prospective and retrospective cohort study
Individuals previously infected with MPXV show strong and durable immunological memory lasting up to 2 years after infection, in contrast to the less robust and shorter-lived response observed after M...
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Andres Meza @nbody6.bsky.social · 24/10/2025
Esto merece ser destacado mil veces ☝️
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Brian Goldstone @brian-goldstone.bsky.social · 24/10/2025
With millions at risk of losing SNAP in the coming days, a reminder: hunger doesn't happen in isolation. When food assistance disappears, families use rent money to eat. Then come evictions and homelessness. Housing, food, healthcare—it's all connected. Cut one thread and the whole thing unravels.
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BK. Titanji @boghuma.bsky.social · 21/10/2025
Three cases of clade Ib mpox not related to travel have been reported in LA. This raises concerns for probable local transmission. Vaccines are available and work to reduce disease severity or prevent infection. If you are eligible to get vaccinated do so. www.theguardian.com/us-news/2025...
theguardian.com
Three cases of severe mpox reported in California, health officials say
Unrelated cases mark first time clade I of disease formerly known as monkeypox has spread within US, officials say
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Thelonevirologist @thelonevirologist.bsky.social · 17/10/2025
Ebola virus in Kasai revives 50-year-old questions on viral latency www.thelancet.com/journals/lan...
thelancet.com
Ebola virus in Kasai revives 50-year-old questions on viral latency
On Sept 4, 2025, DR Congo declared its 16th Ebola virus outbreak. The epicentre of this outbreak occurred in the Kasai province—the first resurgence in this region since 2008.1 Genomic analysis identi...
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Kathleen Bachynski @bachynski.bsky.social · 17/10/2025
“So far this year, over eight thousand cases of whooping cough have been recorded nationwide based on data from the CDC. Over one thousand of those cases are [in] Florida. “Well, the numbers are really alarming. It’s a warning to all of us,” said Dr. Ronald Lee Lindsay” @jackiantonovich.bsky.social
wokv.com
‘The numbers are really alarming’: Former pediatrician shares thoughts on the rise of whooping cough
So far this year, over eight thousand cases of whooping cough have been recorded nationwide based on data from the CDC. Over one thousand of those cases are here in Florida.
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BK. Titanji @boghuma.bsky.social · 16/10/2025
Excellent comprehensive review on #Syphilis just published in #JAMA. An old disease and a powerful mimic. Interpreting syphilis serologies and how to treat is probably one of the consult questions ID physicians get the most. #IDSky #MedSky jamanetwork.com/journals/jam...
jamanetwork.com
Syphilis: A Review
This review summarizes the epidemiology, clinical manifestations, staging, and diagnosis of syphilis.
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UW Infectious Disease Fellowship Program @uwidfellowship.bsky.social · 12/10/2025
Spike in Mpox cases in Chicago prompts public health warning… #IDSky wgntv.com/health/spike...
wgntv.com
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