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brunolemaitre.bsky.social

@brunolemaitre.bsky.social
250 followers 30 following 18 posts
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Mark A. Hanson @hansonmark.bsky.social · 24/06/2026
Over the moon! It's an incredible honour to be named a Lister Prize fellow. And excited to begin this project! We will be building genetic tools (esp. GAL4/UAS) in #Drosophila testacea, a non-model mushroom-feeding fly with a *natural balancer chromosome* to study immune evolution 🧬🪰🍄 1/2
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brunolemaitre.bsky.social @brunolemaitre.bsky.social · 17/06/2026
A short, informal intro to Drosophila genetics (with a French accent 🇫🇷): key concepts & techniques for new lab members. www.epfl.ch/labs/lemaitr...
epfl.ch
Short Introduction to Drosophila_Engl
If you like French accent:A short and informal introduction to Drosophila genetics, covering the basic knowledge and techniques that may be helpful when working with Drosophila. This series of short l...
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brunolemaitre.bsky.social @brunolemaitre.bsky.social · 03/03/2026
Homogamy=career boost. Our study explores the complex ties between love, fame, and creativity in music. Singers with singer romantic partners achieve earlier & more sustained success—especially women. www.nature.com/articles/s41...
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brunolemaitre.bsky.social @brunolemaitre.bsky.social · 10/12/2025
A summary and an interview on our extensive reproducibility project in Drosophila immunity. actu.epfl.ch/news/scienti...
actu.epfl.ch
Scientists investigate 400 biological cold cases
A team of EPFL scientists tested the reproducibility of five decades of research on fly immunity. Most of those research results proved to be valid, but the team made one surprising discovery: the non...
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brunolemaitre.bsky.social @brunolemaitre.bsky.social · 24/11/2025
An open webinar on our reproducibility project 'WHAT 400 DROSOPHILA PAPERS Teach Us about Doing Better Science' on December 9th 2PM EEST time (1PM Swiss time). Registration below
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Mark A. Hanson @hansonmark.bsky.social · 24/10/2025
Bizarre that our 2020 #Drosophila #AMP review already feels out of date. Thanks to #AnnualReviews to cover the many updates in the field and present a much more complete picture of the diversity, mechanisms, topics, of fly immunity re: host defence peptides. www.annualreviews.org/content/jour...
Diagrams of fruit fly larvae (left) and adult (right) annotated with genes expressed in different tissues, including male- or female-biased gene expressions.A diagram providing an overview of the regulation of antimicrobial peptide and other host effector peptides by Toll and Imd signalling, alongside diagrams showing the diversity of the peptides.A summary table illustrating sequence features common to antimicrobial peptides, and a summary table of gene families.A diagram giving a model for the mechanisms of antimicrobial peptide and host defence peptide actions in killing microbial cells, including precise mechanisms, broader host-pathogen relationships, and non-microbicidal roles of these peptides in protecting the host.
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Drosophila Spain @drosospain.bsky.social · 11/10/2025
Model organisms, in particular non-mammalian model organisms, such as yeast, Caenorhabditis elegans, #Drosophila and zebrafish, have long stood at the centre of biological discovery www.nature.com/articles/s41...
nature.com
Reaffirming the value of model organisms in training scientific minds - Nature Cell Biology
As biomedical research prioritizes human models and translational promise, classic model organisms are increasingly dismissed. Here we argue that they have a lasting value, both in enabling discovery and in cultivating scientific thinking, by training researchers in systems reasoning, integrative thinking and independent inquiry.
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Anthony Berndt @anthonyberndt.bsky.social · 15/08/2025
As someone who ended up using non-model systems after doing his PhD with Drosophila, you don't realise just how amazing FlyBase or WormBase are until you try to genetics without them.
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Reposted by @brunolemaitre.bsky.social
flymuscles @flymuscles.bsky.social · 27/08/2025
I read the preprint. It's very beautiful work from Hadi Boukhatmi's group. They test how if at all #Drosophila can repair their #muscles. www.biorxiv.org/content/10.1...
biorxiv.org
Immune–tracheal intercellular signalling coordinates the muscle injury response in Drosophila
Effective tissue adaptation to damage requires precise coordination among diverse cell types. In skeletal muscle, injury-responsive cells play a pivotal role in repair, yet the molecular and cellular ...
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brunolemaitre.bsky.social @brunolemaitre.bsky.social · 27/08/2025
Currently reading Brave Genomes by Silvia Bulgherisi — a wonderful book on recent advances in genomics, environmental change, and the influence of microbes. Highly recommend! shop.elsevier.com/books/brave-... www.amazon.de/Brave-Genome...
shop.elsevier.com
Brave Genomes
The role of environmentally triggered genetic and epigenetic changes in microbial adaptation and evolution is still not broadly appreciated. Brave Gen
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brunolemaitre.bsky.social @brunolemaitre.bsky.social · 16/07/2025
Comment on our @Reproducibility project in @Drosophila immunity. It is a normal that findings—however exciting and important at the time—may later prove to be more complex than initially believed. Re-evaluations is essential to the self-correcting nature of science. www.science.org/content/arti...
science.org
Majority of fruit fly immunity studies can be replicated, huge analysis finds
Verification of 50 years of data bolsters immunology research, but identifies “suspicious” papers that don’t hold up
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James Albert @gymnotus.bsky.social · 15/07/2025
the strain on academic publishing could be substantially alleviated if funding agencies stipulated... work they support must be published in non-profit journals.
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Mark A. Hanson @hansonmark.bsky.social · 10/07/2025
Specifically on the #metascience side, congrats to @josephlemaitre.bsky.social and @brunolemaitre.bsky.social on this consequential piece. 🎉 By dissecting factors associated with #reproducibility within a single field, there are broad lessons for #ScientificPublishing and broader #science.
biorxiv.org
A retrospective analysis of 400 publications reveals patterns of irreproducibility across an entire life sciences research field
The ReproSci project retrospectively analyzed the reproducibility of 1006 claims from 400 papers published between 1959 and 2011 in the field of Drosophila immunity. This project attempts to provide a...
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Reposted by @brunolemaitre.bsky.social
Mark A. Hanson @hansonmark.bsky.social · 10/07/2025
The "reproducibility crisis" in science constantly makes headlines. Repro efforts are often limited. What if you could assess reproducibility of an entire field? That's what @brunolemaitre.bsky.social et al. have done. Fly immunity is highly replicable & offers lessons for #metascience A 🧵 1/n
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European Drosophila Society @fly-eds.bsky.social · 02/07/2025
Congratulations to @fly-eds.bsky.social board member Gábor Juhász @juhg.hu and to Oren Schuldiner @schuldinerorenlab.bsky.social for their election to EMBO membership! #Drosophila
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the Node @the-node.bsky.social · 26/06/2025
#FlyCROSS is a mentor-mentee matching program for the fly community. They're looking for mentors from all career paths (academia, industry, policy etc.) who have experience with #Drosophila research and are eager to support the next generation of fly scientists. Apply to become a mentor by 14 July:
thenode.biologists.com
FlyCROSS 2025–26: Mentor-mentee matching program - the Node
Call for Mentors from the Drosophila community. The Fly Board is excited to announce the second cycle of FlyCROSS (2025–2026), following a successful
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Royal Society Publishing @royalsocietypublishing.org · 17/06/2025
Michael Ashburner FRS was an influential figure in the fields of Drosophila genomics and early sequencing database initiatives such as @ebi.embl.org. Read about their contributions across genetics and bioinformatics in the new biographical memoir: buff.ly/f01zNat @geneticscam.bsky.social‬
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eLife @elife.bsky.social · 13/06/2025
Hidden virus harboured by fruit flies may influence experimental accuracy. buff.ly/TtHCYLQ
drosophila melanogaster
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Sarah Tuttle @niais.cryptoanarchy.network · 03/06/2025
Oh man, you guys. This is so important. Drosophila have led to so much in terms of what we understand about how genes work.
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Mark A. Hanson @hansonmark.bsky.social · 15/05/2025
Big #Drosophila news!🪰 The AMP mutant lines from Hanson et al. (elifesciences.org/articles/443...) & the many isogenic immunity strains generated by @lmvteixeira.bsky.social & @brunolemaitre.bsky.social's group are now in @vdrc-flies.bsky.social! Find the 40 DrosDel Immunity Panel strains at ⬇️
shop.vbc.ac.at
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brunolemaitre.bsky.social @brunolemaitre.bsky.social · 28/05/2025
We are happy to annouce that we have deposited at @VDRC (ViennaDrosophila Resource Center) a list of isogenized @Drosophila immunity mutants affecting all major immune modules and effectors. We hope these strains will be useful to the community. epfl.ch/labs/lemaitr...
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Reposted by @brunolemaitre.bsky.social
James Briscoe @jamesbriscoe.bsky.social · 17/04/2025
Sad news. Benny Shilo, a pioneer in dev bio & Drosophila genetics, has died. I'll remember the infectious enthusiasm and burning curiosity he brought to every conversation I had with him.
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Reposted by @brunolemaitre.bsky.social
Mark A. Hanson @hansonmark.bsky.social · 01/04/2025
Some hashtags: #immunity #Dros25 #Drosophila #antimicrobialpeptides #NFkB #inflammation #ImmunoSky #Infection #pathogen And if you want to learn more about these modules and how you could incorporate them in your research, check our our free book: "The Drosophila Immunity Handbook" bit.ly/3z429p5
The Drosophila Immunity Handbook cover, showing flies that are either glowing green or not. All flies are infected by a green-expressing bacteria, but only red-eyed flies glow green because those flies are missing immune genes needed for resistance to infection.
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Mark A. Hanson @hansonmark.bsky.social · 01/04/2025
Excited to finally announce this work which has been in the pipeline for 5 years: Layers of Immunity. Faustine et al. made a set of immune mutants covering 4 major immune modules in #Drosophila, deleting melanization (ROS), phagocytosis, and both Toll & Imd NF-kB responses. What did we find? 1/n 🧵
biorxiv.org
Layers of immunity: Deconstructing the Drosophila effector response
The host innate immune response relies on the cooperation of multiple defense modules. In insects and other arthropods, which have only innate immune mechanisms, four main immune-specific modules cont...
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brunolemaitre.bsky.social @brunolemaitre.bsky.social · 21/03/2025
Does marrying a fellow scientist boost your career? In academia, homogamous couples—where both partners are scientists—are common, especially among top achievers. But who benefits more? Let’s dive into our latest research!
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European Drosophila Society @fly-eds.bsky.social · 20/02/2025
Recently completed your #PhD using #Drosophila in a European lab? Apply for the European Drosophila Society best thesis prize! 🏆🪰 Deadline: 28 Feb 2025. Prize = €1000 & keynote presentation at the EDRC in Alicante @edrc2025.bsky.social! Info here: europeandrosophilasociety.org/eds-best-phd...
europeandrosophilasociety.org
EDS best PhD thesis prize | European Drosophila SocietyHome
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Ben Longdon @blongdon.bsky.social · 28/01/2025
Workshop on ecological & evolutionary immunology/insect immunity. 15-19th Sept 2025 - Werbellinsee, Germany, organised by Sophie Armitage and Jens Rolff. Abstract deadline start of March www.bcp.fu-berlin.de/en/biologie/...
bcp.fu-berlin.de
Home
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brunolemaitre.bsky.social @brunolemaitre.bsky.social · 20/01/2025
We are recruiting one postdoc and one PhD student to join our lab on #Drosophila #innate immunity in Lausanne (Switzerland). More info: www.epfl.ch/labs/lemaitr...
epfl.ch
Open Positions
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EDRC2025 @edrc2025.bsky.social · 11/12/2024
The European Drosophila Society @fly-eds.bsky.social has just launched a #prize to the best #PhD thesis using #Drosophila. 🏆🪰 Deadline is Feb 2025. Prize = €1000 & keynote presentation at the #EDRC2025 @edrc2025.bsky.social ! More info here: europeandrosophilasociety.org/eds-best-phd...
europeandrosophilasociety.org
EDS best PhD thesis prize | European Drosophila SocietyHome
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Maureen Barr @barrlab.bsky.social · 06/01/2025
I am so sad to lose Dr. Ruth Steward. She was a groundbreaking scientist and a fierce role model for #WomenInScience. This photo is our dinner group with seminar speaker @rburdine1.bsky.social and @lacefieldlab.bsky.social @schindlerlab.bsky.social (1/27/2020). May her memory be an inspiration.
Five women scientists at a restaurant (Soni Lacefield, Maureen Barr, Becky Burdine, Karen Schindler, Ruth Steward)
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brunolemaitre.bsky.social @brunolemaitre.bsky.social · 06/12/2024
I am happy to host Pierre Cosson (University of Geneva) for an hybrid seminar entitled “How phagocytic cells kill bacteria” on Monday December 9 at 3PM (UTC+1) in the room SV1717a @EPFL @phagocytosis epfl.zoom.us/j/66422058690
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