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Ed Feil

@edfeil.bsky.social
374 followers 660 following 16 posts

Bacterial genomes and whatnot. University of Bath.

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Reposted by Ed Feil
Jo Rhodes @drjorhodes.com · 07/08/2026
Nice work from ECRs @poojapadmakumar.bsky.social, Adam, and Pilvi, writing a PLoS Pearl on surveillance of fungal pathogens using wastewater With @edfeil.bsky.social @jusher.bsky.social journals.plos.org/plospathogen...
journals.plos.org
Wastewater surveillance as an early warning system for fungal pathogens
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Reposted by Ed Feil
Manuel Ares-Arroyo @aresarroyom.bsky.social · 14/01/2026
Bacteria chromosomes contain Genomic Islands that provide virulence, antibiotic resistance, MGE-defence,... They transfer between cells, but the mechanism of most remains elusive. Here we explore the conjugative capacity of these mysterious Genomic Islands. www.biorxiv.org/content/10.6...
biorxiv.org
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Ed Feil @edfeil.bsky.social · 07/01/2026
It has been a long road, but our paper on Klebsiella plasmids is finally out in Lancet Microbe. Thanks to all co authors but especially Marjorie Gibbon and Natacha Couto www.sciencedirect.com/science/arti...
sciencedirect.com
Convergence and global molecular epidemiology of Klebsiella pneumoniae plasmids harbouring the iuc3 virulence locus: a population genomic analysis
Klebsiella pneumoniae is an important pathogen of humans and animals. In the past five years, increasing reports of convergent strains that carry both…
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Reposted by Ed Feil
Daniel Padfield @padpadpadpad.bsky.social · 16/09/2025
I have an MRC-funded PhD project available (www.exeter.ac.uk/study/fundin...) on how warming will change the problem of AMR. Join a small and friendly group (padpadpadpad.netlify.app/about) in (sometimes) sunny Cornwall. 🧪🦠 #microsky Please share the ad below with anyone who may be interested.
A teal flyer for a PhD opportunity to investigate how warming may change antimicrobial resistance. The project will use experiments on Klebsiella bacteria to answer questions about how temperature affects their response to antibiotics, plasmid transfer, and fitness costs. The research involves microbiology lab work, bioinformatics, and mathematical modeling. The flyer includes contact details for Dr. Daniel Padfield and the logos of the sponsoring institutions.
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PLOS Biology @plosbiology.org · 15/07/2025
Mutations generate variation, critical for #evolution, but #MutationBias restricts the choice of mutation type. @deepaagashe.bsky.social &co use #Ecoli strains with different mutation biases to show that changing an old bias should yield more beneficial mutations @plosbiology.org 🧪 plos.io/46LjCRt
Schematic of the key prediction tested in this work. As the transversion (Tv) mutation bias of WT E. coli is shifted away from the ancestral bias, the resulting distribution of fitness effects (DFE) is predicted to change. Specifically, it should shift left with a bias reinforcement, with a lower fraction of beneficial mutations. In contrast, reversing the ancestral bias is predicted to cause right-shifted DFEs with higher proportions of beneficial mutations.
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Reposted by Ed Feil
Jo Rhodes @drjorhodes.com · 20/05/2025
Our JPIAMR grant (led by @edfeil.bsky.social) is ramping up, and Bath are looking for a research associate to work on Candida epidemiology for this project. Come work with us! www.myscience.org/jobs/id31031...
myscience.org
Research Associate in Candida One-Health genomic epidemiology - University of Bath - job portal | jobs.myScience
Job title Research Associate in Candida One-Health genomic epidemiology
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Ed Feil @edfeil.bsky.social · 20/05/2025
www.bath.ac.uk/jobs/Vacancy... Post doc available to work on Candida genomics with me at the Milner Centre for Evolution (U Bath, UK) as part of the JPIAMR funded project Fugaci www.jpiamr.eu/projects/fug... For queries, email me!
jpiamr.eu
FuGACI – JPIAMR
JPIAMR is a global collaborative organisation and platform, engaging 28 nations to curb antimicrobial resistance (AMR) with a One Health approach.
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Jose A Escudero @jaescudero.bsky.social · 08/05/2025
🧪 Finally out after peer review, our work showing that "Mobile #Integrons carry Phage Defense Systems" is now published in Science 🎉 Short 🧵 www.science.org/doi/10.1126/...
science.org
Mobile integrons encode phage defense systems
Integrons are bacterial genetic elements that capture, stockpile, and modulate the expression of genes encoded in integron cassettes. Mobile integrons (MIs) are borne on plasmids, acting as a vehicle ...
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Uli Klümper @ulikluemper.bsky.social · 29/04/2025
Antimicrobial effects, and selection for AMR by non-antibiotic drugs in a wastewater bacterial community by @aprilhayes.bsky.social, @edfeil.bsky.social, @willhgaze.bsky.social, @profjrsnape.bsky.social, @ecehh.org et al. www.sciencedirect.com/science/arti...
sciencedirect.com
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Ed Feil @edfeil.bsky.social · 12/04/2025
PhD on C.diff epidemiology with me and Barbara Kasprzyk-Hordern to join the new centre cwbe.ac.uk @bathchem.bsky.social www.findaphd.com/phds/project...
cwbe.ac.uk
CWBE CWBE
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Ed Feil @edfeil.bsky.social · 06/03/2025
The website for our new centre of excellence in water-based early-warning systems for health protection is now live : cwbe.ac.uk follow us at @cwbe.bsky.social
cwbe.ac.uk
CWBE CWBE
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Daniel Padfield @padpadpadpad.bsky.social · 15/11/2024
I'm advertising a PhD studentship (open to international students) on understanding how temperature may alter the ecology and evolution of AMR. Might suits someone with a microbiology/wet lab background who wants to expand into ecoevo. Or vice versa! But interest more important than experience.
An advert for a PhD investigating how and why temperature may alter the ecology and evolution of antibiotic resistance.
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Reposted by Ed Feil
Zamin Iqbal @zaminiqbal.bsky.social · 11/11/2024
I'm advertising a PhD studentship (open to international students) working on long read pangenome / assembly algorithms in bacteria. Would suit someone with maths/compsci/coding background. Aptitude + interest more important than experience. Details here: www.findaphd.com/phds/project...
findaphd.com
New graph algorithms for analysis of the genomes and pangenomes of bacteria and their mobile elements. at University of Bath on FindAPhD.com
PhD Project - New graph algorithms for analysis of the genomes and pangenomes of bacteria and their mobile elements. at University of Bath, listed on FindAPhD.com
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Ed Feil @edfeil.bsky.social · 09/11/2024
Hi. Thought it was time to join the grown-ups!
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