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Yunn-Hwen Gan

@yunnhwengan.bsky.social
34 followers 43 following 6 posts

Teaching and doing research at the National University of Singapore. Co-chair of Infectious Diseases Translational Research Program. Studied Burkholderia in former life. Now found new light and passion in Klebsiella pneumoniae!

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Yunn-Hwen Gan @yunnhwengan.bsky.social · 24/09/2026
Our new paper is online and describes how antibiotic treatment #AMR versus osmotive laxative pre-exposure alters the gut environment leading to different colonization outcomes and evolutionary fates of hypervirulent #Klebsiella pneumoniae! onlinelibrary.wiley.com/share/CJFYDB... #Microsky #UTIsky
onlinelibrary.wiley.com
Different gut microbiome dysbioses impact the evolutionary fate of hypervirulent Klebsiella pneumoniae
Reader environment loaded
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Reposted by Yunn-Hwen Gan
Ákos T Kovács @evolvedbiofilm.bsky.social · 26/07/2026
Expression of conjugation genes is controlled by a novel zipper-type transcriptional attenuation mechanism (pLS20 in Bacillus subtilis) @narjournal.bsky.social from Wilfried Meijer and @paulbabitzke.bsky.social academic.oup.com/nar/article/...
academic.oup.com
Expression of conjugation genes is controlled by a novel zipper-type transcriptional attenuation mechanism
Abstract. Proper expression of genes clustered in operons, particularly large operons, can be complex, often involving multiple regulatory switches. The co
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Reposted by Yunn-Hwen Gan
Craig MacLean @craigmaclean.bsky.social · 27/06/2026
New #microsky#AMR Perspective paper with @penamiller.bsky.social rdcu.be/fqBJo ANTIBIOTIC RESISTANCE (IE MIC) AND TOLERANCE ARE NOT BACTERIAL TRAITS! Please read on if you want an explanation for this provocative claim.
rdcu.be
Beyond resistance and tolerance: rethinking evolutionary responses to antibiotics from the perspective of individual bacterial cells
Nature Communications - Beyond resistance and tolerance: rethinking evolutionary responses to antibiotics from the perspective of individual bacterial cells
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Reposted by Yunn-Hwen Gan
Emma Slack @mucosalimmunology.bsky.social · 01/07/2026
We are recruiting a lab manager for my group in Oxford. This is a lovely team doing great things, and you could be an important part of it! See here: www.path.ox.ac.uk/vacancy/lab-... Please spread the word!
path.ox.ac.uk
Lab Manager - Molecular Immunology - Dunn School
Laboratory Manager/Senior Scientist position in the Molecular Mucosal Immunology group at Oxford
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Rebecca D. Burdine, PhD @rburdine1.bsky.social · 03/06/2026
Take a look friends (and journal publishers). Peer review is valuable, and if you pay for the labor, everyone benefits. "Expanded implementation of Fast & Fair paid peer review reduces time to first decision without reducing review quality in a biology journal" www.biorxiv.org/content/10.6...
biorxiv.org
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Reposted by Yunn-Hwen Gan
Daniel Cazares @danielcazares.bsky.social · 03/06/2026
Phage constrain multidrug resistance spread #Phage #Plasmid #AMR #EvolutionaryBiology #CraigMacLeanLab The final version of our paper is out in @isme-microbes.bsky.social academic.oup.com/ismej/articl... bsky.app/profile/dani... More exciting phage and plasmid research coming soon!
academic.oup.com
Eco-evolutionary responses to plasmid-dependent phage constrain the spread of multidrug-resistance plasmids
Abstract. Phage therapy offers an alternative to antibiotics for treating multidrug-resistant infections. Plasmid-dependent phages (PDPs) are promising the
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Yunn-Hwen Gan @yunnhwengan.bsky.social · 25/05/2026
If you are interested in hypervirulent #Klebsiella pneumoniae and liver abscess, pls take a look at our short review on Host interactions of hvKp along the gut liver axis! #microsky #UTIsky authors.elsevier.com/sd/article/S...
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Yunn-Hwen Gan @yunnhwengan.bsky.social · 12/05/2026
Finally I migrated here after a hiatus of a few years! Hoping to interact with many friends new and old interested in microbial pathogenesis, AMR and of course #Klebsiella pneumoniae!!! Still learning to navigate around...
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