Sign in

Francois Lebreton

@flebreton.bsky.social
167 followers 234 following 5 posts

Director of bioinformatics at WRAIR-MRSN. Interests in microbial genomics, antimicrobial resistance and bacterial evolution.

PostsRepliesMedia
Reposted by Francois Lebreton
sylvain Brisse @sylvainbrisse.bsky.social · 26/11/2025
Cumulative cgMLST : Our novel preprint is out @biorxiv doi.org/10.1101/2025...
doi.org
Cumulative cgMLST provides increased discrimination of nested phylogenetic groups
Background Core genome multilocus sequence typing (cgMLST) is a powerful method for bacterial strain genotyping. However, the size of the core genome decreases as the phylogenetic breadth of the targe...
1166
Francois Lebreton @flebreton.bsky.social · 18/02/2026
New preprint out! Anjali Sapre, Melissa Martin and co. mapped the evolutionary routes of convergence in K pneumo. Pop analysis of >1,400 global genomes & 7,500 closed plasmids to see how #AMR & virulence genes come together and impact phenotypes. www.researchsquare.com/article/rs-8...
researchsquare.com
Preferred evolutionary routes of convergence in Klebsiella pneumoniae favor siderophore acquisition over hypervirulence
The rise of Klebsiella pneumoniae combining antimicrobial resistance and virulence genes poses a major health threat, but the evolutionary routes and phenotypic consequences of this convergence are po...
1187
Reposted by Francois Lebreton
sylvain Brisse @sylvainbrisse.bsky.social · 17/04/2025
Please visit: www.icarecourse.org @ICARe_AMR has a great atmosphere and location @LesPensieres , with a unique faculty and a special session on #AMR #genomics with François Lebreton @flebreton.bsky.social and myself – great opportunities for networking and scientific discussions
042
Reposted by Francois Lebreton
Eduardo Rocha @epcrocha.bsky.social · 16/04/2025
New postdoc position in our lab (2 y+): evolutionary genomics of integrons and MGEs with focus on vibrio-phage interactions. Great environment @pasteur.fr for science, career building. Super collaborators @celineloot.bsky.social @amazeld.bsky.social @fredoleroux.bsky.social 3 weeks to apply!
2100124