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Clara Torres-Barceló

@clara-inrae.bsky.social
818 followers 247 following 22 posts

Researching the diversity and interaction of phages with plant pathogenic bacteria 🌱🔬 | INRAE | PHIM | Montpellier, France. 🇵🇸

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Reposted by Clara Torres-Barceló
Vivek Mutalik @vivekmutalik.bsky.social · 29/09/2026
🎉 Scaling Phage-Bacteria Interaction Contexts: From Pairwise Mechanisms to Community Dynamics www.annualreviews.org/content/jour... #phagesky
annualreviews.org
Scaling Phage-Bacteria Interaction Contexts: From Pairwise Mechanisms to Community Dynamics
Bacteriophages (phages), viruses that parasitize bacteria, hold tremendous potential as antimicrobial agents, microbiome modulators, and industrial biocontrol tools; yet clinical and environmental app...
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Reposted by Clara Torres-Barceló
Nature Microbiology @natmicrobiol.nature.com · 29/09/2026
Out Now! Phylogeny-agnostic strain-level prediction of phage–host interactions from genomes using machine learning #MicroSky
go.nature.com
Phylogeny-agnostic strain-level prediction of phage–host interactions from genomes using machine learning
Nature Microbiology, Published online: 29 September 2026; doi:10.1038/s41564-026-02482-5This platform identifies phages capable of infecting specific bacterial strains using genome sequences alone and could enable rational phage-therapy design and precision microbiome engineering.
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Reposted by Clara Torres-Barceló
Evelien Adriaenssens @evelienadri.bsky.social · 25/09/2026
Here are my first thoughts as a phage person about the @anthropic.com announcement about a novel enzyme on a phage: www.linkedin.com/pulse/my-tho...
linkedin.com
My thoughts on the Anthropic phage enzyme discovery
* Disclaimer: This is not a scientific review, just a few thoughts I had while reading..
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Jorge Moura de Sousa @jmouradesousa.bsky.social · 20/09/2026
Happy to see our work on the evolution of antiviral repertoires in P4-like satellites and their P2-like helper phages (check out the 🧵 👇) out in @narjournal.bsky.social 🔗 doi.org/10.1093/nar/... #phagesky #MicroSky #evosky
doi.org
Shuttling, swapping, and mixing: the rapid modular evolution of antiviral repertoires in temperate phages and their satellites
Abstract. Interactions between bacteria, bacteriophages, and their satellites are shaped by a myriad of defence and counter-defence mechanisms. Here, we id
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Benoit Pons @benoitjpons.bsky.social · 17/09/2026
🧬Phages in Toulouse — November 18–20, 2026! 🦠 We are delighted to announce the next edition of Phages.fr congress, Phages in Toulouse, bringing together the phage research community for 3 days of talks, presentations & scientific discussions! 📍 Toulouse, France 📅 Nov. 18–20
phages.fr
Réseau Bactériophage France
Bienvenue sur le site du réseau “Phages.fr” Le réseau “Phages.fr” regroupe des scientifiques qui travaillent sur les thématiques incluant les bactériophages dont l’étude des structures, interactions moléculaires & cellulaires, écologie & évolution, thérapie phagique et biocontrôle en santé humaine, végétale & animale et industrie ainsi que des Sciences humaines et sociales. Ces scientifiques appartiennent à différents instituts publics français de recherche tels que CNRS (principal financeur), INRAE, INSERM, ANSES, Institut Pasteur mais aussi de nombreuses universités (Bordeaux, Lyon, Marseille, Montpellier, Nancy, Paris, etc) et hôpitaux, avec aussi la participation de membres d’entreprises.
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Ellinor Alseth @ellinoralseth.bsky.social · 11/09/2026
It's finally published! What a journey @brownlab.bsky.social and I have been on with this one (ask me about it over a pint 🍻). Super excited to be able to say that it's finally out in Trends (author gift link to follow)! 🦠🧫 #phagesky
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Meaghan Castledine @mcastd.bsky.social · 10/09/2026
🦠Fully funded PhD project with myself, Angus Buckling, Jo Lello and Phil Mitchelmore🦠 How should we design phage therapeutics for bacterial co-infections? How do interactions between pathogens affect treatment efficacy? Please get in touch if you have any Qs 💃 shorturl.at/39Xea
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Rafal Mostowy @rafalmostowy.bsky.social · 04/09/2026
🧬 Postdoc ad is now live: evolutionary genomics of Klebsiella pneumoniae phages. How do prophage depolymerases vs SGNH-esterases shape phage host range? Krakow, Poland. Deadline 21 Sept: mostowylab.com/job-postdoc-...
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PLOS Biology @plosbiology.org · 21/08/2026
Why do most cross-species #virus jumps fail? @sfelenalab.bsky.social &co use Orsay virus across multiple Caenorhabditis species to reveal how mismatches in replication, genome balance and transmission create layered barriers to #spillover @plosbiology.org 🧪 plos.io/4gCVoxg
Top: Barrier-resolved framework for OrV host competence across Caenorhabditis species. Conceptual summary of the seven barriers evaluated in this study and the expected empirical signature if each barrier limits OrV host competence. The framework distinguishes early susceptibility/establishment, within-host replication kinetics, RNA2:RNA1 genome-segment balance, luminal localization consistent with egress or viral material accumulation, functional transmission, virulence, and evolutionary persistence under serial passage. Bottom: Representative smiFISH images of OrV infection in alternative host species, showing C. elegans and the alternative host species at 24 hours post-inoculation (hpi).
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PLOS Biology @plosbiology.org · 03/09/2026
Identifying #antiphage defense systems can be challenging. This study by @duerkoplab.bsky.social describes a #bioinformatic pipeline that uses a small serine recombinase as a genetic marker to identify novel antiphage defense systems across diverse bacterial phyla. 🧪 #AcademicSky plos.io/4i4ZrUu
RADS leverages small serine recombinases associated with antiphage defense.
(A) Graphic depicting the locus that inspired RADS. EF_B0058 is a serine recombinase that is co-transcribed with EF_B0059, a Type IV restriction enzyme on the large conjugative plasmid pTEF2. (B) Graphic depicting the RADS bioinformatic pipeline.
(bottom) Alphafold3 modeling of KAP P-Loop NTPase domain (red) containing proteins with RUFs (green).
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Martial Marbouty @mmarbout.bsky.social · 30/08/2026
🚨 ‼️ NEW PUBLICATION ‼️ While we start to know a lot about how bacterial genomes are organized in 3D, almost nothing is known about phage genome once it enters a bacterial cell. read the paper here: www.science.org/doi/10.1126/...
science.org
Bacteriophage PAK_P3 genome structuration and dynamics during infection of Pseudomonas aeruginosa reveal specific interaction patterns
While the dynamic changes in genome organization in cellular organisms have been well described, the three-dimensional (3D) folding of phage genomes during the infection of their host is extremely lim...
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Harmit Singh Malik @harmitmalik.bsky.social · 20/07/2026
I wish I did not have to bring up this old tweet from ‘that other place’ every now and again but here we are (again) and here it is…
A reminder: the scientific accomplishments of serial sexual harassers do not make up for the grievous injury caused to science & young scientists over generations (even if this were a simple math argument which... WTF!). This 'genius myth' protects such folks in the first place.
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Joshua Weitz @joshuasweitz.bsky.social · 15/07/2026
Bacteriophage continue to have so much to teach us. It's in our interest to understand how they work and impact human & environmental health. New joint work led by @mariandm.bsky.social & @rantahan.bsky.social inferring single-cell latent period & burst size heterogeneity from population dynamics.
science.org
Inferring single-cell heterogeneity of bacteriophage lysis-associated life-history traits from population-scale dynamics
Theory-guided experiments reveal single-cell heterogeneity of lysis-associated bacteriophage traits from population scale data.
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Rafal Mostowy @rafalmostowy.bsky.social · 15/07/2026
PhD opening in my lab @jagiellonskiuni.bsky.social: using AI to predict how phage enzymes break down bacterial capsules — joint work with ML group GMUM and Zuzanna Drulis-Kawa's phage lab (Wrocław), spanning genomics, AI & evolution. mostowylab.com/job-phd-ai-d... Deadline: 15 August 2026
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Clara Torres-Barceló @clara-inrae.bsky.social · 12/07/2026
Fantastic #VOM2026 in Prague! 3 posters on phage ecology & evolution in plants: 🌾 Phage–bacteria co-evolution in rice paddies – #SarahDelafosse 🦠 Phageome as plant disease biomarker – @mariandm.bsky.social 🌳 Apricot phageome (from @chloe-feltin.bsky.social 's work) Great science, great vibes!
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Ákos T Kovács @evolvedbiofilm.bsky.social · 04/07/2026
Host Range Breadth Correlates with Genic Diversity in Honeybee Phages @genomebiolevol.bsky.social from @chicascientifica.bsky.social academic.oup.com/gbe/article/...
academic.oup.com
Host Range Breadth Correlates with Genic Diversity in Honeybee Phages
Abstract. Bacteriophages can evolve rapidly. Mutation and recombination via horizontal gene transfer allow them to counter adaptive responses by microbial
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Reposted by Clara Torres-Barceló
Ákos T Kovács @evolvedbiofilm.bsky.social · 01/07/2026
Phage biocontrol reduces the disease burden and modulates plant immunity through suppression of bacterial virulence @cp-cellreports.bsky.social by Erdrich, @mtkeilhammer.bsky.social et al from @borjana-a.bsky.social @frunzkelab.bsky.social @guidogrossmann.bsky.social www.cell.com/cell-reports...
cell.com
Phage biocontrol reduces the disease burden and modulates plant immunity through suppression of bacterial virulence
Erdrich et al. investigated the molecular interplay underlying bacteriophage-based biocontrol, using natural bacterial viruses for plant protection. They uncovered that phage-treated plants maintain b...
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Reposted by Clara Torres-Barceló
ISVM @isvm-society.bsky.social · 24/06/2026
📢 Join us at the ISVM General Meeting during #VoM2026 in Prague! 📅 6 July 2026 🕠 17:30–18:30 📍 Prague, Czech Republic We'll discuss: 🔹 ISVM development 🔹 Activities for members 🔹 Future directions and member engagement Programme: www.vom2026.org/program #ISVM #Virology #Microbiology #Phages
VOM2026
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Nature Microbiology @natmicrobiol.nature.com · 24/06/2026
Out Now! Phages tame plant pathogens #MicroSky
go.nature.com
Phages tame plant pathogens
Nature Microbiology, Published online: 23 June 2026; doi:10.1038/s41564-026-02395-3Predicting infection heterogeneity requires looking beyond the host. Phage–bacteria coevolution in tomato fields maintains diverse bacterial strategies and explains uneven disease occurrence across plant populations.
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Marie Simonin @microbialmarie.bsky.social · 23/06/2026
📆 Save The Date! The Plant-Bacteria Interaction Meeting (18th RPB) in Aussois, Savoie will take place from January 11 to 15th, 2027 👉 More info on the keynote speakers & sessions: plants-bacteria-2027.symposium.inrae.fr Deadline: September 25th @inrae-dpt-spe.bsky.social @sfp-france.bsky.social
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Jesse Shapiro @bjesseshapiro.bsky.social · 15/06/2026
How useful are phages in explaining cholera disease severity? Accordingly to our latest little paper, possibly quite useful — up there with patient age and hospital location, and possibly more important than antibiotic exposures!
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Ville Friman @frimanscience.bsky.social · 12/06/2026
Very happy that this piece of research finally sees the daylight! Super nice collaboration between Nanjing, York and Helsinki. Fun fact: we started this work over 10 years ago when I was working as a fellow at Imperial College. Sometimes good things come to those who wait.
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Piotr Rozwalak @prozwalak.bsky.social · 11/05/2026
Mushuvirus is the most widespread phage genus in the human gut. 🌍 Together with other family members, these viruses occur in 89% of humans worldwide, including the Iceman Ötzi! How is it possible that they were hidden in previous metagenomic analyses? [1/7] Read: doi.org/10.64898/202...
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Britt Koskella @bkoskella.bsky.social · 19/05/2026
Please share widely! Abstract submissions open for the 2026 Jacques Monod conference: Ecology and evolution of host-parasite interactions in a changing world! Held in beautiful Roscoff France from November 2- 6, 2026. Abstracts submission deadline : June 6 cjm.sb-roscoff.fr/en/conferenc...
cjm.sb-roscoff.fr
Ecology and evolution of host-parasite interactions in a changing world | CNRS - Conférences Jacques Monod (CJM)
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Luisa De Sordi @luisadesordi.bsky.social · 18/05/2026
I had fun writing a short commentary on the importance of integrating prophage biology into microbiome research 🦠 Now out in @cp-cellhostmicrobe.bsky.social #microbiomesky #phagesky www.cell.com/cell-host-mi...
cell.com
Making room for gut prophages in human health
Prophages are pervasive in the human gut yet largely overlooked in microbiome research, despite substantial functional potential. Emerging evidence indicates that prophages regulate bacterial fitness,...
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Reposted by Clara Torres-Barceló
Vivek Mutalik @vivekmutalik.bsky.social · 17/05/2026
Phages as ecosystem engineers of plant microbiomes: Cell Host & Microbe www.cell.com/cell-host-mi...
cell.com
Phages as ecosystem engineers of plant microbiomes
Phages modulate plant microbiomes through bacterial lysis and by equipping bacteria with auxiliary genes through lysogeny. In this Forum, we highlight the underappreciated role of phages in plant heal...
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Clara Torres-Barceló @clara-inrae.bsky.social · 29/04/2026
🚨 We’re looking for a PhD student to join @phimresearch.bsky.social and explore phages in emerging rice epidemics 🌾 We will investigate phage–bacteria interactions and the seed microbiome/phageome. #phd #phage #plantscience #microbiome #scijobs ‪ 👉 More info: tinyurl.com/yhc2fa7
filesender.renater.fr
FileSender
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Simon Roux @simrouxvirus.bsky.social · 24/04/2026
www.nature.com/articles/s41...
nature.com
Phage host range: determinants, dynamics and applications - Nature Reviews Microbiology
Comprehensive assessment of the host range of phages is a prerequisite for their safe and effective use in multiple applications but is rarely undertaken. This Review outlines the molecular and ecolog...
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PlantEvolution 🌱🌾 @plantevolution.bsky.social · 16/04/2026
1/8 🔥 New preprint dropped: Dynamic co-existence of bacteriophages and their hosts 🦠 in the Arabidopsis thaliana 🌱 phyllosphere Work led by the indomitable @sheilaroitman.bsky.social‬ #plantscience #microbiome #holobiont www.biorxiv.org/content/10.6...
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Enric Frago @enricfrago.bsky.social · 13/04/2026
New paper published: aggressive ladybirds, slow-eating lacewings, and parasitoids greedy for resources. #BES #JAE besjournals.onlinelibrary.wiley.com/doi/10.1111/...
besjournals.onlinelibrary.wiley.com
Consumption competition by a parasitoid wasp opens a window of survival under intraguild predation
Our study reveals a previously overlooked mechanism enabling coexistence under intraguild predation. Using long-term experiments and behavioural tests, we show that consumption rates and aggressive b...
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Greenpeace EU @greenpeace.eu · 06/04/2026
Greenpeace's ship Arctic Sunrise will join the Global Sumud Flotilla leaving Barcelona on 12 April, to help break the siege on Gaza 1000+ people on 70+ vessels will show the world's solidarity with the people of Gaza, while governments have failed to uphold international law and prevent genocide
Photo of ship at sea with seagulls around it

Text reads: Greenpeace will join the next global Sumud Flotilla to help break the siege on Gaza
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Vivek Mutalik @vivekmutalik.bsky.social · 03/04/2026
📣Huge preprint 🔔 Today we share something our group has been working toward for a long time, led by @lucasmoriniere.bsky.social We asked can we predict which receptor a phage targets from its genome sequence alone? For most phages, we couldn’t. So Lucas set out to do something I had only dreamed of.
Phage receptor prediction from genome sequencing alone. Bacterial receptor (blue) interacting with phage proteins (purple) is shown here
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Waggoner Lab @labwaggoner.bsky.social · 01/04/2026
Global source of cholera & role of phage in controlling evolution/spread of Vibrio cholerae lineages within the current 7th pandemic @nature.com @sangerinstitute.bsky.social @amberbarton.bsky.social @ucberkeleyofficial.bsky.social www.nature.com/articles/s41... www.nature.com/articles/s41...
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FEMS @femsmicro.org · 08/03/2026
Happy #IWD2026 to our FEMS community and to everyone working to advance microbiology across Europe and beyond. To mark the day, we are sharing reflections from across our community on the FEMS blog buff.ly/TSSQccE Thank you to all the women in microbiology for the impact you make every day.
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Stu West @stuwest.bsky.social · 04/03/2026
New paper showing that bacteria with more genes for cooperation can live in a broader range of habitats and that genes for cooperation are more more likely to be in the accessory genome www.pnas.org/doi/10.1073/... @lauriebelch.bsky.social
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ISVM @isvm-society.bsky.social · 25/02/2026
🔬 𝐢𝐕𝐨𝐌 𝟐𝟎𝟐𝟔 𝐎𝐧𝐥𝐢𝐧𝐞 𝐂𝐨𝐧𝐟𝐞𝐫𝐞𝐧𝐜𝐞 𝐒𝐞𝐫𝐢𝐞𝐬 – 𝐒𝐞𝐬𝐬𝐢𝐨𝐧 𝟑: Viromics⁣⁣ ⁣⁣ 🗓 25 Feb 2026⁣⁣ ⏰ 17:00 CET | 11:00 EST | 08:00 PST⁣⁣ ⁣⁣ 👉 Register for links & updates:⁣⁣ 🔗 isvm.org/ivom/%E2%81%... ⁣⁣ #iVoM #VoM2026 #Virology #ECRs #OnlineEvent
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Waggoner Lab @labwaggoner.bsky.social · 23/02/2026
The enteric virome, dominated by bacteriophages, can autonomously activate host immune signaling to modulate intestinal metabolic responses @cp-cellhostmicrobe.bsky.social www.cell.com/cell-host-mi...
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Clara Torres-Barceló @clara-inrae.bsky.social · 18/02/2026
Back to Madagascar 🇲🇬 for our 2nd phage field season: exploring eco-evolutionary dynamics in rice fields. Aiming to limit sampling to just 1 year of lab + bioinformatics 😅! Great teamwork between Xplain (@phimresearch.bsky.social) and FOFIFA @mariandm.bsky.social #microsky #phagesky #phage #inrae
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Paul Turner Lab @paulturnerlab.bsky.social · 05/02/2026
How does population density affect evolutionary trajectory? Microbes construct their own niche which in turn reshapes their evolution. Preprint drop from grad student @noahhoupt.bsky.social whose evolution experiments featured blue/white colonies, 1000 generations, a lab move, and much more!
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Olaya Rendueles @olayarendueles.bsky.social · 27/01/2026
TnPedia provides a curated framework for understanding prokaryotic transposable elements doi.org/10.1016/j.ti... www.sciencedirect.com/science/arti...
sciencedirect.com
Emerging advances in prokaryotic transposition: TnPedia as a promising tool
TnPedia provides a curated framework for understanding prokaryotic transposable elements (TEs), including general and historical information and basic…
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Ryan Cook @ryancook94.bsky.social · 09/10/2025
Happy to say this has now been published in @cp-cellreports.bsky.social 🫁🦠 #Phages #Viromics www.cell.com/cell-reports...
cell.com
Bacteriophage diversity declines with COPD severity in the respiratory microbiome
Cook et al. reveal bacteriophage diversity progressively declines with COPD severity. Frequent exacerbators uniquely show decoupled viral-bacterial relationships. Virulence-encoding phages associate w...
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Microbiome Virtual International Forum @microbiomevif.bsky.social · 23/01/2026
It's Friday! ...and a new #MVIF program is out! 🤩 Free registration: cassyni.com/s/mvif-46 Highlights: 🇺🇸 Rebecca L. Knoll 🇯🇵 Akito Sakanaka Keynote: 🇺🇸 @simrouxvirus.bsky.social ⭐️ Talks: 🇦🇺 @jeremyjbarr.bsky.social 🇨🇦 @erikbakkeren.bsky.social 🇨🇳 Guanxiang Liang
mvif 46 program
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Clara Torres-Barceló @clara-inrae.bsky.social · 14/01/2026
#microsky #phagesky #phage At last! Great to see this one out: journals.plos.org/plospathogen... Here, we discovered a nested phage-bacteria network despite their high genetic and ecological diversity. Kudos to everyone involved, especially @chloe-feltin.bsky.social ! @phimresearch.bsky.social
journals.plos.org
Ecological ubiquity and phylogeny drive nestedness in phages–bacteria networks and shape the bacterial defensome
Author summary Viruses that infect bacteria, known as phages, are part of microbial communities and influence the abundance, diversity, and traits of their hosts. In an agriculture-related context, th...
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Joshua Weitz @joshuasweitz.bsky.social · 12/01/2026
Viruses transform microbes, populations, & ecosystems. In new work jointly led w/@tn-marine-micro.bsky.social + more, we find a link between enhanced viral infection and productivity 50 meters below the surface in the otherwise nutrient limited Sargasso Sea. a 🧵 www.nature.com/articles/s41...
"Seasonal enhancement of the viral shunt catalyzes a subsurface oxygen maximum in the Sargasso Sea"
https://www.nature.com/articles/s41467-025-67002-1
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Luisa De Sordi @luisadesordi.bsky.social · 05/01/2026
🚨 New paper from our lab in Cell Reports @cp-cellreports.bsky.social, led by Clara Douadi! We show that bacteriophages can cross the intestinal barrier, with increased translocation in Crohn's disease. 🔗 www.cell.com/cell-reports... Many thanks to all the authors!
cell.com
Differential translocation of bacteriophages across the intestinal barrier in health and Crohn’s disease
Intestinal barrier integrity is crucial for gut homeostasis. Douadi et al. show that bacteriophages can cross this barrier without causing damage and that translocation rates depend on the barrier sta...
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Emmanuele Severi @emmseveri.bsky.social · 15/12/2025
#microsky #microbiomesky The #microbiome of living trees! How cool! www.nature.com/articles/s41...
nature.com
A diverse and distinct microbiome inside living trees - Nature
Microbiome analyses of living trees show that a single tree can host approximately one trillion bacteria, with microbial communities distinctly partitioned between heartwood and sapwood and with minim...
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Marie Simonin @microbialmarie.bsky.social · 13/12/2025
Check our new perspective paper exploring how the seed holobiont goes to sleep 😴 and reactivate for germination. A lot of exciting research to be done to understand dormancy mechanisms in microbes and plants ☘️ @emersys-irhs.bsky.social @irhs-angers.bsky.social
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Evelien Adriaenssens @evelienadri.bsky.social · 11/12/2025
I'm proud to share the latest methods work from my group. Led by @revathykri.bsky.social we wrote a book chapter on how we process and analyse viromes. Thanks to co-authors @rikhaagmans.bsky.social @ryancook94.bsky.social & Alise Ponsero link.springer.com/protocol/10....
link.springer.com
Virome Analysis
Viruses are omnipresent and the most abundant biological entities on the planet. They play a critical role in shaping the ecology and evolution of all life forms. This chapter provides methods to perf...
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PLOS Biology @plosbiology.org · 28/11/2025
Capsule diversity limits #phage host range by affecting receptor-binding protein (RBP) interactions in capsulated #bacteria. @pilardomingoc.bsky.social &co show that generalist phages evolve host range via RBP mutation & recombination, but specialists remain stable @plosbiology.org 🧪 plos.io/48nvOqY
Graphic representation of the recombination events in the Sugarlandvirus I and J variants. Top left: Representation of the variants isolates in the different strains in the three lines. Genome fragments of each parent are represented in a different color. Regions with the most abundant recombination events are marked and associated with a schematic representation of the functional annotation and intergenomic similarity between the two parental phages. Bottom left: 3D folding of the RBPγ. The consensus recombinant region, which is associated with the infection of the K-type 47, is represented in light orange. Variable positions detected in the protein sequence alignment of the variants are represented as hot pink spheres. The table indicates the percentage of identity of the parental protein sequences in three protein regions limited by the amino acids indicated. Right: Transmission electron microscopy (TEM) image of Klebsiella myoviruses artificially coloured, showing their characteristic contractile tails and icosahedral capsids. Image acquired by the Environmental and Biomedical Virology group (Institute for Integrative Systems Biology, Universitat de València-CSIC).
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