Epithelial cell extrusion in a sea anemone shares key hallmarks with bilaterians and is dynamically regulated by nutritional status. During starvation-induced body shrinkage, extrusion likely contribu...

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The updated OrthoFinder v3 software boosts accuracy and scalability in phylogenetic orthology inference with massive and diverse datasets.

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Singh et al. combine cryo-electron microscopy and functional studies to reveal how a single protein complex selects diverse mRNAs for subcellular localization using a combination of shape, positional ...

Gene expression patterns underlie development, but their systematic detection in whole embryos has remained elusive. We introduce a whole-embryo imaging platform using multiplexed error-robust fluores...

Epigenetic landscapes were proposed by Waddington as the central concept to describe cell fate dynamics in a locally low-dimensional space. In mode...

The ascidian tunicate Ciona, one of the closest relatives of the vertebrates, inhabits shallow temperate waters in the worldwide ocean. A unique combination of simple stereotyped embryogenesis, regula...

Vignettes that reveal how numbers serve as a sixth sense to understanding our cells

imageimageDuring development, multipotent cardiopharyngeal progenitors express both cardiac and pharyngeal muscle transcriptional programs. This study in the tunicate Ciona shows that cell cycle-regul...

The morphogenetic events that occur during gastrulation involve dramatic cell- and tissue-level changes. Here they show that propagation of nematic order, leading to long-range spatial correlation, is...

The Michael Sars Centre is launching a Visitors Program designed to foster scientific exchange and collaborations across disciplines.

Anoctamins play a key role in sensory perception in mammals. A new article by the Chatzigeorgiou group reveals their dual role in perception and larval metamorphosis in the chordate Ciona.

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