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Lionel Christiaen, PhD (he/him/his)

@lionlchristiaen.bsky.social
1.5K followers 2.1K following 532 posts

Developmental cell & systems biologist. Director of the Michael Sars Centre, University of Bergen (Norway). French & American. www.uib.no/en/michaelsarscentre/141…

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Reposted by Lionel Christiaen, PhD (he/him/his)
James Briscoe @jamesbriscoe.bsky.social · 20h
Philip Ball wrote a thoughtful popsci piece in @quantamagazine.org on Waddington’s landscape for cell fate decisions Includes our work with David Rand using dynamical systems theory & single-cell data to make the landscape metaphor quantitative & predictive www.quantamagazine.org/how-does-lif...
quantamagazine.org
How Does Life Unfold? A Landscape Metaphor Comes Into Its Own. | Quanta Magazine
C.H. Waddington’s powerful image of embryonic stem cells specializing on a rolling landscape has captivated biologists since the 1950s. Experimental data is finally confirming, and complicating, his v...
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Reposted by Lionel Christiaen, PhD (he/him/his)
allen institute @alleninstitute.org · 08/10/2026
Scientists at Seattle Hub for Synthetic Biology just built the largest cellular family tree ever for a mammal, tracing how a single egg divided into 1.28 million cells. bit.ly/4zqcRjh
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Reposted by Lionel Christiaen, PhD (he/him/his)
Andres Bendesky @bendeskylab.com · 04/10/2026
10 days left to apply for an Assistant Professorship in Evolutionary Biology at Columbia.
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Reposted by Lionel Christiaen, PhD (he/him/his)
Jean Léon Maître @maitrejl.bsky.social · 06/10/2026
📣Our department is hiring a new group leader!📣 Want to start your team in a vibrant scientific environment in the center of Paris? I was very lucky to do that 10 years ago, reach out if you have any question. Apply by December 18th: jpi-recruitment-curie-umr3215-u934.curie.fr
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Reposted by Lionel Christiaen, PhD (he/him/his)
Michael E. Mann @michaelemann.bsky.social · 30/09/2026
New record global sea surface temperature anomaly. This El Niño is for reals pulse.climate.copernicus.eu
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Lionel Christiaen, PhD (he/him/his) @lionlchristiaen.bsky.social · 30/09/2026
To quote @hejnol.bsky.social “when it’s nice, it’s REALLY nice!” #SunnyBergen
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Reposted by Lionel Christiaen, PhD (he/him/his)
Mark Peifer (He, him) @peiferlabunc.bsky.social · 29/09/2026
For the last 34 years I have been on the faculty of the UNC-Chapel Hill Department of Biology and have never regretted that decision. This year we are hiring TWO new Assistant Professors in the broad area of Molecular, Cell, Developmental Biology 1/n bio.unc.edu
Front page of the website
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Lionel Christiaen, PhD (he/him/his) @lionlchristiaen.bsky.social · 25/09/2026
Wonderful to welcome Rémi @rdumollard.bsky.social from @imev-mer.fr and Angelica @migliolia.bsky.social from @chemamd.bsky.social lab on a very #SunnyBergen day for a tag-team seminar @msarscentre.bsky.social
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Reposted by Lionel Christiaen, PhD (he/him/his)
Bart⚓️ @bartgonnissen.bsky.social · 23/09/2026
The Facial Expressions of Tethys by artist Julius von Bismarck. A suspended high-sea buoy that moves in real time. Sensors on a twin buoy out in the Atlantic Ocean send live satellite data to motors inside the museum. This makes the indoor buoy copy the exact, real-time movements of the ocean waves.
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Lionel Christiaen, PhD (he/him/his) @lionlchristiaen.bsky.social · 22/09/2026
“Jamming with comb jellies” yesterday at the innovation day, our very own @pawelburkhardt.bsky.social teamed up with the Department of Music in a fantastic #SciArt performance tuning live music to the graceful aquatic dance of comb jellies.
Presenter Pawel Burkhardt pointing at a blue slide showing a picture of a comb jelly behind a tank containing swimming comb jelliesMusicians sitting ready to start jamming yo the rhythm of swimming comb jellies.
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Reposted by Lionel Christiaen, PhD (he/him/his)
James Talarico @jamestalarico.bsky.social · 12/09/2026
BREAKING: Our banned interview with Kimmel generated 6 million views on YouTube.
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Reposted by Lionel Christiaen, PhD (he/him/his)
Philippe Batut @philippebatut.bsky.social · 10/09/2026
🧬🔬 Why are enhancers transcribed and how does that impact gene regulation? I’m really excited to share our new paper in @science.org showing that noncoding RNAs control the timing of gene activation in embryos. With Mike Levine #ScienceResearch @columbiamed.bsky.social A few highlights below... 🧵👇
science.org
Noncoding transcription controls the developmental dynamics of long-range gene regulation
The genomic regions regulating gene expression are often themselves transcribed into a variety of noncoding RNAs (ncRNAs). However, the regulatory roles of this noncoding transcription remain largely ...
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Reposted by Lionel Christiaen, PhD (he/him/his)
mainewomenforward.bsky.social @mainewomenforward.bsky.social · 07/09/2026
This cartoon was created by Pulitzer Prize winning artist Adam Zyglis for The Buffalo News in November, 2024. It hits even harder now.
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Reposted by Lionel Christiaen, PhD (he/him/his)
Carlos Cano-Barbacil @canobarbacil.bsky.social · 03/09/2026
🚨Our latest paper is out today in #NatureHumanBehaviour 🧐Are academic systems stifling scientific creativity? We argue that short-term funding, productivity metrics and risk-averse research disproportionately constrain early-career researchers www.nature.com/articles/s41...
nature.com
How contemporary academic structures constrain scientific creativity and hold back early-career researchers - Nature Human Behaviour
In this Perspective, Haubrock et al. argue that today’s scientific structures constrain creativity and that strategic conformity is a rational response. They discuss how this holds back early-career r...
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Reposted by Lionel Christiaen, PhD (he/him/his)
PLOS Biology @plosbiology.org · 29/08/2026
Dynamical systems theory can be used for cell state mapping during cell fate decisions. This study by @jamesbriscoe.bsky.social &co presents a Dynamic Landscape Analysis, revealing how morphogen signals orchestrate #cellFate decisions during #neuralTube development. 🧪 #AcademicSky plos.io/4wPoVsn
An expanded detail of the dynamical landscape of cell fate decisions for ventral neural tube progenitors illustrating the circular topology of differentiation trajectories that leads to p3 neurons.
(CC BY 4.0; https://creativecommons.org/licenses/by/4.0/).
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Reposted by Lionel Christiaen, PhD (he/him/his)
Simon Kuestenmacher @simongerman600.bsky.social · 29/08/2026
What do Europeans actually care about? Source: link.europa.eu/TJB8hy
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Reposted by Lionel Christiaen, PhD (he/him/his)
Codfather #FBPE 🇫🇷🇪🇺 @codfather.bsky.social · 26/08/2026
Excellent - it's what everyone should do.
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Lionel Christiaen, PhD (he/him/his) @lionlchristiaen.bsky.social · 26/08/2026
On a good #SunnyBergen day, whether you want to be in the lab, on a boat or on a mountain, the visitors program at @msarscentre.bsky.social is there. www.uib.no/en/michaelsa... 😁🔬🧬🧪
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Reposted by Lionel Christiaen, PhD (he/him/his)
Dr. Lucky Tran @luckytran.com · 25/08/2026
Do not normalize children dying from measles. Measles was previously eliminated in the US, thanks to vaccines. When children die from measles, it means that adults have catastrophically failed to protect them because they have rejected basic science.
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Reposted by Lionel Christiaen, PhD (he/him/his)
Marc Elias @marcelias.bsky.social · 23/08/2026
Many of you are asking how you can help me. My only ask is this: Spread the word about the threats to democracy and how we can fight back. Tell everyone to subscribe to Democracy Docket and share its content. demdock.com/4w6emld
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Lionel Christiaen, PhD (he/him/his) @lionlchristiaen.bsky.social · 21/08/2026
We are in for another at @msarscentre.bsky.social with Javier Ortega-Hernandez on a North American perspective into the Cambrian explosion.
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Reposted by Lionel Christiaen, PhD (he/him/his)
Luca @lucagalletti.bsky.social · 21/08/2026
Horrifyingly creative 👌 #art #painting #sculpture #creepy IG: @tanya
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Reposted by Lionel Christiaen, PhD (he/him/his)
Luis Alberto Bezares Calderón @lbezarescalderon.bsky.social · 16/08/2026
Our team is recruiting a PhD student to investigate the evolution of pressure sensation in Zooplankton! The project will use marine invertebrate larvae to explore the molecular, cellular, and neuronal mechanisms behind this fascinating sensory system. More details here: bit.ly/3TTeF4Q
bit.ly
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Lionel Christiaen, PhD (he/him/his) @lionlchristiaen.bsky.social · 14/08/2026
Exciting restart of our guest seminar series @msarscentre.bsky.social on transcriptional potency and the origins of developmental gene regulation by César Arenas-Mena.
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Reposted by Lionel Christiaen, PhD (he/him/his)
Albert Ruhí @albertruhi.bsky.social · 08/08/2026
We're hiring an ecologist at UC Berkeley! The Dept. of Integrative Biology is hiring a tenure-track Assistant Professor in Ecology. Plants/algae, invertebrates, microbes, or marine systems a priority. Come join us!! Apply by Oct 5, 2026. aprecruit.berkeley.edu/JPF05489 PS: Please share!
aprecruit.berkeley.edu
Assistant Professor –Ecology- Integrative Biology
University of California, Berkeley is hiring. Apply now!
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Reposted by Lionel Christiaen, PhD (he/him/his)
BWJones @bwjones.bsky.social · 07/08/2026
This is 572 5 year biomedical research grants to study cancer, heart disease, blindness, Alzheimer’s, epilepsy, diabetes, infectious disease, etc…
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Reposted by Lionel Christiaen, PhD (he/him/his)
The Guardian @theguardian.com · 08/08/2026
This burning summer is the proof: the voices of climate denial aren’t just delusional, they’re deadly | Sadiq Khan
theguardian.com
This burning summer is the proof: the voices of climate denial aren’t just delusional, they’re deadly | Sadiq Khan
Look at our blazing forests and parched cities. Green policies aren’t a ‘luxury’, and we can’t burn more oil and gas. People need the truth, says London mayor Sadiq Khan
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Reposted by Lionel Christiaen, PhD (he/him/his)
Inés Fournon Berodia @inesfournon.bsky.social · 04/08/2026
Very pleased to finally share the main story from my PhD, now published in @natcomms.nature.com ! 🎉 Using a sea anemone we discovered and characterised epithelial cell extrusion as the mechanism underlying starvation-induced cell loss. 🔗 Open-access article: www.nature.com/articles/s41...
nature.com
Epithelial cell extrusion underlies starvation-induced cell loss in a sea anemone - Nature Communications
Epithelial cell extrusion in a sea anemone shares key hallmarks with bilaterians and is dynamically regulated by nutritional status. During starvation-induced body shrinkage, extrusion likely contribu...
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Reposted by Lionel Christiaen, PhD (he/him/his)
Ariaa® @ariaa.bsky.social · 03/08/2026
Happy 65th Birthday, August 4th, to the best President in US History. The black man "they" feared, led with humor, dignity & grace for 8 yrs scandal-free, has a beautiful & accomplished family, and is beloved by millions around the world. @barackobama.bsky.social #BarackObama #ThePeoplesPresident
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Reposted by Lionel Christiaen, PhD (he/him/his)
bioRxivpreprint @biorxivpreprint.bsky.social · 23/07/2026
A tight balance of anabolic mTORC1 signaling and catabolic autophagic activity regulates zebrafish heart regeneration www.biorxiv.org/content/10.64898/20…
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Lionel Christiaen, PhD (he/him/his) @lionlchristiaen.bsky.social · 22/07/2026
Same 🤓
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Reposted by Lionel Christiaen, PhD (he/him/his)
Codfather #FBPE 🇫🇷🇪🇺 @codfather.bsky.social · 16/07/2026
As we say, religion poisons everything. All that wasted time.
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Reposted by Lionel Christiaen, PhD (he/him/his)
Margherita Battistara @mbattistara.bsky.social · 08/07/2026
🪲🪰 Our preprint is out! This was a team effort with @wolframponisch.bsky.social, @matthewabenton.bsky.social and Ewa Paluch. We asked whether Drosophila and Tribolium use the same cell behaviours to fold their embryos during gastrulation. 🧵👇 www.biorxiv.org/content/10.6...
biorxiv.org
Morphospace analysis reveals divergent cellular behaviours driving tissue internalisation during insect gastrulation
During gastrulation, embryonic epithelia undergo large-scale remodelling to internalise the mesoderm. Whether the cellular mechanisms underlying these tissue deformations are conserved across species ...
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Reposted by Lionel Christiaen, PhD (he/him/his)
Michael Sars Centre @msarscentre.bsky.social · 07/07/2026
Congratulations to @simonhenriet.bsky.social and colleagues for their groundbreaking work on the evolution of intron splicing, now out in @narjournal.bsky.social 👏 They looked in unprecedented detail at the machinery of non-canonical splicing in larvaceans 🧬⤵
academic.oup.com
Deployment of non-canonical splicing in tunicate genomes is mediated by divergent U2AF function and changing m6A modification in U1 and U6 snRNA
Abstract. Spliceosomal small nuclear RNA (snRNA) U1 and the U2AF heterodimer play critical functions by recognizing the highly conserved GT and AG dinucleo
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Reposted by Lionel Christiaen, PhD (he/him/his)
Pawel Burkhardt @pawelburkhardt.bsky.social · 07/07/2026
Thrilled to present our labs's work on the syncytial nerve net in #ctenophores - offering a different view on neural organization and signaling - later today as part of the wonderful symposium: Origins & Diversifications of Neural Systems at #FENS2026. fens2026.abstractserver.com/program/#/de...
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Reposted by Lionel Christiaen, PhD (he/him/his)
vlecaudey.bsky.social @vlecaudey.bsky.social · 06/07/2026
New paper from the lab! We show that laminin α5 and two integrin receptors (α3, α6) team up to guide a group of cells moving together inside a living embryo (doi.org/10.1242/dev....) Congrats Anna & Nicola. Thanks to @chaitanyadingare.bsky.social and all authors, and to @dev-journal.bsky.social.
doi.org
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Reposted by Lionel Christiaen, PhD (he/him/his)
Cam Hostinar, Ph.D. @camhostinar.bsky.social · 03/07/2026
“Every dollar invested in NIH-funded research returned about $2.50 to the broader economy — a 250% return on investment.” “…sustained NIH funding has generated more than $822 billion in economic activity, supported more than 3.7 million jobs” academicmedicine.aamc.org/stories/how-...
academicmedicine.aamc.org
Client Challenge
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Reposted by Lionel Christiaen, PhD (he/him/his)
James Briscoe @jamesbriscoe.bsky.social · 02/07/2026
Paying peer reviewers Interview with @danielgorelick.bsky.social about @biologyopen.bsky.social Fast & Fair trial in which peer reviewers were paid £220/review Spoiler: it works - fast, high quality reviews www.nature.com/articles/d41...
nature.com
Why paying peer reviewers works, according to a journal’s editor-in-chief
A biology journal that paid peer reviewers found that the approach cut the time to a first editorial decision by 85% and maintained high-quality reviews.
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Lionel Christiaen, PhD (he/him/his) @lionlchristiaen.bsky.social · 02/07/2026
Congratulations on a richly deserved accolade. 👏🏻👏🏻👏🏻
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Reposted by Lionel Christiaen, PhD (he/him/his)
Gaurav Vaidya @gvaidya.bsky.social · 01/07/2026
The first preprint from my PhD is out! :thread: How does an animal choose between two completely different reproductive fates? Here’s how one planarian does it :point_down: www.biorxiv.org/content/10.6...
biorxiv.org
Life-cycle trajectory inference links temperature-gated progenitors to reproductive fate
Temperature shapes reproductive strategies across animals, yet how individuals switch between sexual and asexual reproduction remains unknown. We establish the planarian Phagocata morgani as a model f...
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Reposted by Lionel Christiaen, PhD (he/him/his)
Loïc A. Royer 💻🔬🧪 @loicaroyer.bsky.social · 29/06/2026
1/ 🧬🔬 How does one cell become an entire animal? We can now film it in 3D 🐟, but turning those movies into accurate cell tracks is brutally hard. Enter our new #Kaggle challenge: $60K prize pool, to help crack 3D+time cell tracking at scale! 🧵👇 www.kaggle.com/competitions... @biohub.org
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Reposted by Lionel Christiaen, PhD (he/him/his)
Teun Huijben @teunhuijben.bsky.social · 29/06/2026
🚨Open call to the Cell Tracking crowd out there🚨! Loïc's team at @biohub.org opened our Kaggle Challenge for 3D cell tracking, with $60k of prize money💰. Spread the news, delve into our gigabytes of imaging (zarr3) and cell tracking (geff) data of developing zebrafish embryos, and start tracking 🤩
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Reposted by Lionel Christiaen, PhD (he/him/his)
Susan Gregurick @sgregurick.bsky.social · 29/06/2026
www.sciencedirect.com/science/arti... 🧪 researchers developed a modular framework that integrates partial differential equations for continuum microenvironmental gradients, agent-based model for spatially explicit cell-cell interactions, and Boolean state networks for intracellular decision-making.
sciencedirect.com
MISSTE: a multiscale integrative spatial simulator for understanding the mechanisms underlying tissue ecosystems
Multiscale tissue ecosystems are governed by coupled intracellular decision-making, cell-cell interactions, and spatially structured microenvironmenta…
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Reposted by Lionel Christiaen, PhD (he/him/his)
Michael Sars Centre @msarscentre.bsky.social · 29/06/2026
PhD candidate @chiaracastelletti.bsky.social from the group of @lionlchristiaen.bsky.social presented her work at the #EED2026 conference earlier this month 💡 She shares her experience and discusses a shift in focus towards organismal biology in the context of climate change ⤵
uib.no
Studying development in a changing climate: insights from the EED 2026
PhD candidate Chiara Castelletti from the Christiaen group at the Michael Sars Centre attended the 10th European Society for Evolutionary Developmental Biology Meeting, a landmark in the field of evo-...
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Reposted by Lionel Christiaen, PhD (he/him/his)
UCL Institute of Ophthalmology @ucleye.bsky.social · 24/06/2026
Lecturer in developmental biology, genetics and/or omics at UCL Institute of Ophthalmology. Join a world-leading vision research institute and help advance our understanding of eye disease. Closing 21 July. Apply: www.ucl.ac.uk/work-at-ucl/... #VisionResearch #Genetics #AcademicJo
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Reposted by Lionel Christiaen, PhD (he/him/his)
tenuretracker.info @tenuretracker.bsky.social · 26/06/2026
New York University is hiring: Postdoctoral Researcher in Developmental Biology #postdoc
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Reposted by Lionel Christiaen, PhD (he/him/his)
Manuel Mendoza @longchrom.bsky.social · 22/06/2026
This article in Le Monde about French research in general and the CNRS in particular has a few depressing graphs www.lemonde.fr/sciences/art...
The graph highlights a growing divergence between Germany and France:

* In the mid-1990s, France and Germany spent similar shares of GDP on R&D.
* Germany subsequently increased its R&D investment by about 1 percentage point of GDP.
* France’s R&D effort remained largely stagnant.
* By 2023, Germany spends 3.15% of GDP on R&D compared with 2.18% in France, a gap of nearly 1 percentage point of GDP.
* France is also well below the OECD average (2.93%).

The figure therefore illustrates that France has fallen behind both Germany and the OECD average in R&D intensity over the past three decades.

Sources listed on the graphic: OECD database, UNESCO, ANR, ERC; infographic by Le Monde.
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Reposted by Lionel Christiaen, PhD (he/him/his)
Mike Dorrity @mwdorr.bsky.social · 19/06/2026
First pre-print from the lab, a collaborative effort led by Jess Bourn @bournsupremacy.bsky.social, a fantastic PhD in my group. We resolve a key problem in development + evolution: how do we quantify heterochrony and link temporal variation to phenotype? www.biorxiv.org/content/10.6...
biorxiv.org
Quantitative mapping of heterochrony to species-specific phenotypes
The genetic program of animal development is conserved, but its rate of execution varies across species. Heterochrony, shifts in the relative timing of developmental events, generates phenotypic varia...
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Reposted by Lionel Christiaen, PhD (he/him/his)
International Society of Developmental Biology @isdb.bsky.social · 19/06/2026
Happy #FluorescenceFriday. This stunning light sheet video of a 🪰 embryo was taken by a student from our 2026 EMBO course in Quintay. If you'd like a chance to learn and take images like this, consider apply: biodesarrollo.unab.cl/how-to-apply ‼️Deadline for the 2027 course is 30th July 2026‼️
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Reposted by Lionel Christiaen, PhD (he/him/his)
Michael Sars Centre @msarscentre.bsky.social · 19/06/2026
Excellent talk this morning by Prof. Inna Sokolova from the University of Rostock 👏 By comparing mollusk species living in intertidal zones, her work aims to uncover the mitochondrial basis of hypoxia resilience 🐌 Thank you for visiting us!
Inna Sokolova presents in front of an audience in a seminar room. On a screen, a title slide in shades of blue and orange reads: "From mitochondria to metabolome: metabolic adaptations in stress-tolerant marine mollusks"
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