Reposted by Lionel Christiaen, PhD (he/him/his)
Philip Ball wrote a thoughtful popsci piece in @quantamagazine.org on Waddington’s landscape for cell fate decisions
Includes our work with David Rand using dynamical systems theory & single-cell data to make the landscape metaphor quantitative & predictive
www.quantamagazine.org/how-does-lif...
quantamagazine.org
How Does Life Unfold? A Landscape Metaphor Comes Into Its Own. | Quanta Magazine
C.H. Waddington’s powerful image of embryonic stem cells specializing on a rolling landscape has captivated biologists since the 1950s. Experimental data is finally confirming, and complicating, his v...