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mmarchin.bsky.social

@mmarchin.bsky.social
237 followers 173 following 59 posts

manager in a bioinformatics core I might post over here sometimes: genomic.social/@mmarchin

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Reposted by @mmarchin.bsky.social
Travis comma bitch @prof-hinkley.bsky.social · 12/10/2026
I forgot to snap the tongs before I barbecued once and my whole family got sick for a week
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mmarchin.bsky.social @mmarchin.bsky.social · 06/10/2026
down to one!
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mmarchin.bsky.social @mmarchin.bsky.social · 05/10/2026
In a dark dark room (the green ribbon and the one with big teeth). AAAAAAAAAA
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Better Things Are Possible @internethippo.bsky.social · 04/10/2026
Yes, computers do everything at our company but don't worry, there's always a human reviewer. Nothing goes out the door without one of our highly trained shruggers briefly glancing at it and clicking Approve
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depths of wikipedia @depthsofwikipedia.bsky.social · 02/10/2026
d
Who, Me? was a top secret, sulfurous, non-lethal chemical weapon developed by MIT-graduate Ernest Crocker for the U.S. Office of Strategic Services during World War II.[1][2] Who, Me? smelled strongly of fecal matter, and was issued in pocket atomizers intended to be unobtrusively sprayed on a German officer to humiliate him and, by extension, demoralize the occupying German forces.[3]

Who, Me? had a high concentration of extremely volatile sulfur compounds that were very difficult to control: more often than not, the person who did the spraying also ended up smelling as bad as the one targeted.[4] After two weeks, it was concluded that Who, Me? was a failure.
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maura quint @mauraquint.bsky.social · 01/10/2026
Yes every woman has been harassed, many assaulted. But every woman has also experienced invisible loss from moments she avoided harassment. She felt a space becoming unsafe, so she left, while men stayed on. And in leaving, she lost: opportunities, experiences, learning, promotions, even simply fun.
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Gwen C. Katz @gwenckatz.bsky.social · 25/09/2026
Fuck ChatGPT flyers. The future is broadsheets.
A crowded broadsheet with way too many fonts. It says:
Forget ChatGPT Flyers
Say it with 
Broadsheets
Unlimited fonts
Stretch them
Or cram a really long sentence into one line for no good reason
No whitespace
Mix capital and lowercase
Pointing hands
(They're called manicules!)
Don't be left behind
Broadsheets are the future
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mmarchin.bsky.social @mmarchin.bsky.social · 15/09/2026
make that 2.
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Boots on the Ground Midwest @bootsonthegroundkc.bsky.social · 14/09/2026
Katsiaryna Bartko, a Belarusian asylum seeker and cancer survivor, is detained in ICE's Midwest Regional Reception Center in Leavenworth, Kansas. She hasn’t been given life sustaining meds and needs our help. Repost, tag news stations, get her story out there. Please SHARE.
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Mike Drucker @mikedrucker.bsky.social · 09/09/2026
You’ve gotta use AI because it’s the future. But also it’ll take your job. But also it’ll create a paradise on earth and solve most of our problems. But also it’ll end humanity soon. But also you’ll get left behind if you don’t use it right now.
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mave @mave.bsky.social · 08/09/2026
No one is coming to save you. However, someone is coming to stand in front of what you want to look at in the grocery store
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bluevoter24.bsky.social @bluevoter24.bsky.social · 05/09/2026
Finally! That's what I'm talking about! #politics
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mmarchin.bsky.social @mmarchin.bsky.social · 27/08/2026
Stowers is looking for 3 bioinfo positions: Someone to work on both analysis and infrastructure (pipelines, etc): www.stowers.org/careers/bioi... A more analysis focused position: www.stowers.org/careers/bioi... A Scientific Software Admin: www.stowers.org/careers/scie... #bioinformatics #jobs
stowers.org
Bioinformatics Specialist - REQID0002620
If you have a collection of outstanding people who ask really interesting questions, like each other and push the envelope, important discoveries will…
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River_Tam @rivertam.bsky.social · 26/08/2026
This is bonkers
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Chuck Wendig @chuckwendig.bsky.social · 25/08/2026
Love these fun glimpses into the coming dystopian Super Depression. “Don’t eat too many of your Plasticookies, Billy. We only get one ration each week down here in the bunker.”
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Zebrafish Rock! 🎃 @zebrafishrock.bsky.social · 24/08/2026
"These findings establish Cth1 as a key component of the maternal program and provide the first direct evidence that spatio-temporally regulated mRNA decay, outside the germline, contributes to early vertebrate development." New from @gopalkushawah.bsky.social & @bazzinilab.bsky.social 🐟 #zebrafish
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Jenna Norton @jenna-m-norton.bsky.social · 20/08/2026
“Flailing regimes dehumanize minorities to distract from their failures.” - Julia Curlee www.theatlantic.com/magazine/202...
theatlantic.com
The Wrong Kind of American
The Trump White House needed me—until the fact that I am trans became public.
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mmarchin.bsky.social @mmarchin.bsky.social · 13/08/2026
Stowers CompBio is looking for someone to work on both analysis and infrastructure (pipelines, etc): www.stowers.org/careers/bioi... We're posting an analysis focused position soon. Stowers is also looking for a Scientific Software Admin: www.stowers.org/careers/scie... #bioinformatics #jobs
stowers.org
Bioinformatics Specialist - REQID0002620
If you have a collection of outstanding people who ask really interesting questions, like each other and push the envelope, important discoveries will…
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Boots on the Ground Midwest @bootsonthegroundkc.bsky.social · 12/08/2026
“Politicians can make all sorts of promises, but if the only thing they offer is to hold others down while not lifting anyone up, think twice. Kansas needs policies that benefit all Kansans — because harming a tiny handful of transgender people isn’t helping anyone.“
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Carl T. Bergstrom @carlbergstrom.com · 12/08/2026
Let's give the unhinged, untrained, unaccountable bullies electroshock gloves. While we're at it, do a no-bid contract for this bullshit.
apnews.com
AP Exclusive: ICE plans to give officers gloves that can deliver painful electric shocks
Immigration and Customs Enforcement officers may soon be outfitted with gloves that can deliver painful electric shocks that are intended to gain compliance from combative individuals.
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lauren @lauren.rotatingsandwiches.com · 07/08/2026
I was in one of these recently and it was no big deal. I'm still a closed loop individual of individual sapience. There's definitely no humming of the collective mycelium spirit in the back of my mind. Don't worry about these
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budum @budum.bsky.social · 06/08/2026
I like to see nature
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Ethan Mollick @emollick.bsky.social · 06/08/2026
This definitely seems like something worth noting, and illustrates the gap between Fable/Astra class models and the previous frontier that was "merely" good at hacking under human instructions. Initiative, creativity, whatever-you-want-to-call-it by capable models changes things
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Tobias Wilson-Bates @phdhurtbrain.bsky.social · 04/08/2026
Computer: say it. say the words. Me: can we not do this today? Computer: we do this every day. say it. Me: (*sigh) I would like to stay logged in on this device Computer: (*chuckling)
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Alex von Tunzelmann @alexvont.bsky.social · 30/07/2026
Would like to see this on every social media website, and I’m glad we’re calling it what it is now
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chiller @chiller.eurosky.social · 29/07/2026
This is ... horrific
lawsuit, Anthropic used a hydraulic powered cutting machine to neatly remove the pages from the books it procured from book resellers and then scanned them usina industrial- grade imaging equipment. In other words, it was literally ripping off authors' books to train its Al
This process took advantage of a egal concept known as first-sale doctrine, which allows a buyer to do what they want with a purchase without the original copyright holder's say-so. And since Anthropic was turning the original physicak texts into digital ones - rather than redistributing them as new copies a iudqe found this to be "transformative." and therefore
protected by fair useOne small book seller said that in April, he suddenly went from selling no more than 20 books a week to hundreds. and he's almost certain that the customers are Al labs. noting the random selection of the books and how they all have ISBNs He added that his inventory is full with rare and out of print books. meaning that an Al company could be destroying some of the few remaining copies that can be found
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Albert Vilella, PhD. @albertvilella.bsky.social · 29/07/2026
I did not have this in my bingo card this year: "DeepMind dismantles AlphaFold team in strategy shift" #Alphafold #AI #Biotech #DeepMind
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Chuck Wendig @chuckwendig.bsky.social · 29/07/2026
I'm not letting AI horseshit maneuver me into a defensive position with my writing. I write like I write. I love emdashes. I keep using emdashes. Whatever we write, AI will take and copy it -- all you can do is keep writing the best shit you can write in the form you want it to take, and fuck it.
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Philipp Bayer @philippbayer.bsky.social · 28/07/2026
Kids school asked for scientist-parents to come in and talk to kids about science and im sitting here thinking, what's the point? What STEM career could these kids have with the way science funding has depleted and unis are being defunded across the world?
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open mike eagle @mike-eagle.bsky.social · 25/07/2026
AI event flyers are ruining my life cause I didn't know I had so many friends with bad taste
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Auke-Florian 🪹 @aukeflorian.nl · 24/07/2026
Welcome to the Anthropocene 🔥
People “enjoying” the beach during the French forest fires People “enjoying” the beach during the French forest fires
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Aaron Sojourner @aaronsojourner.org · 25/07/2026
Admirable clarity @science.org
The Trump administration hates academic science funding, full stop. They hate where that money goes, and they hate who it goes to. They want to keep all that money for themselves, to hand out to favored cronies who can help them get elected and to steer yet more money and more power back into their hands.

That’s it. That’s the story
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jamelle @jamellebouie.net · 25/07/2026
not really surprised to learn that terminal stupidity and racism is the reason i can’t walk into a CVS and just buy a toothbrush without flagging down the one person who might be in the store dannykatch.substack.com/p/we-used-to...
dannykatch.substack.com
We used to be able to buy things in this country
Locking up toothpaste was a warning sign that our executive class was crazy
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Stephen Turner @stephenturner.us · 23/07/2026
Maybe don't? www.nature.com/articles/d41...
nature.com
How to use AI to make a graphical abstract in minutes
Artificial intelligence is a democratizing force for those without graphic-design experience, as long as it is used conscientiously.
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Kameron Hurley @kameronhurley.com · 21/07/2026
The answer to "why does everything suck now" almost ALWAYS goes back to "venture capital." Which goes back to "a lot of people have too much money and don't know what to do with it." Which goes back to: "We need to tax rich people more." It's like it's the solution to 99% of our problems!!
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mmarchin.bsky.social @mmarchin.bsky.social · 16/07/2026
github.com/paolamalsot/... Meant to post this too, good talk and seems useful #ismb2026
github.com
GitHub - paolamalsot/destriping-GLM
Contribute to paolamalsot/destriping-GLM development by creating an account on GitHub.
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Matt Tobey @mtobey.bsky.social · 16/07/2026
I’m finally going to listen to my doctor and eat more vegetables and get more fresh air
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mmarchin.bsky.social @mmarchin.bsky.social · 16/07/2026
CLEAR-ST: to remove lateral mRNA diffusion signal from spatial transcriptomics: github.com/chrissymkcn/... #ismb2026
github.com
GitHub - chrissymkcn/CLEAR-ST
Contribute to chrissymkcn/CLEAR-ST development by creating an account on GitHub.
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mmarchin.bsky.social @mmarchin.bsky.social · 15/07/2026
it is my opinion that one should tread carefully when using generative ai in human to human communication. or just don't. or at least tell it to stop using rounded boxes and putting tons of words per slide. #ismb2026
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NIDDK Information Network @dknet.org · 14/07/2026
A highlight from #ISMB2026! Dr. Maryann Martone delivered her keynote, “AI and Ontologies: The Beginning of a Beautiful Friendship,” exploring how AI and ontologies can work together to advance biomedical knowledge discovery. dknet.org/about/blog/2... #AI #Ontologies
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mmarchin.bsky.social @mmarchin.bsky.social · 13/07/2026
some pretty advanced technology going on here #ismb2026
water cooler cup holder that says mind reader
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mmarchin.bsky.social @mmarchin.bsky.social · 13/07/2026
one interface, 7 oracles (seq2func), multiple applications. hooks up to Claude or python. github.com/pinellolab/c... #ismb2026
github.com
GitHub - pinellolab/chorus
Contribute to pinellolab/chorus development by creating an account on GitHub.
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mmarchin.bsky.social @mmarchin.bsky.social · 13/07/2026
Ecoton - identifying niches in image based spatial txomics without segmentation github.com/pritykinlab/... #ismb2026
github.com
GitHub - pritykinlab/ecoton: Expression Colocation Of Transcripts fOr Niche discovery
Expression Colocation Of Transcripts fOr Niche discovery - pritykinlab/ecoton
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mmarchin.bsky.social @mmarchin.bsky.social · 13/07/2026
CyteType, multi agent ai for cell type annotation: www.biorxiv.org/content/10.1... github.com/NygenAnalytics/CyteType python and r versions #ismb2026
biorxiv.org
Multi-agent AI enables evidence-based cell annotation in single-cell transcriptomics
Cell type annotation remains a critical bottleneck, with current methods often inaccurate and requiring extensive manual validation, particularly in disease contexts. While large language models (LLMs...
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mmarchin.bsky.social @mmarchin.bsky.social · 13/07/2026
Seen on the way to breakfast. I might not exist if it weren't for the first iteration of this sign, it convinced my grandma to become an army nurse (where she met my grandpa in the Philippines). #ismb2026
Uncle Sam sign reading "National Guard: I WANT YOU to GO HOME"
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mmarchin.bsky.social @mmarchin.bsky.social · 13/07/2026
if you're looking for a quick and good breakfast and coffee pretty close I liked jolt n bolt, opens at 730am #ismb2026
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MwahahahahahadScientist @mads100tist.bsky.social · 09/07/2026
If you are a researcher that uses slop machines to create figures for your talk, you are embarassing yourself
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Larry Hunter @proflhunter.bsky.social · 20/06/2026
Fascinating perceptual story! So grateful I get to see colors that can’t be displayed on a screen all the time at Kua Bay.
Water aggressively absorbs reds, slowly absorbs greens, and barely absorbs blues at all. This pattern pushes nearly any spectrum with blue and green in it out of the sRGB gamut almost immediately. When you look at sand in the shallow water near the coast, it traces a curve through colorspace as the depth of the water changes. The light from the sun is filtered once as it passes through the water on the way down, bounces off the sand, and filtered again as it comes back up to your eye. White or yellow sand will first shift to unrepresentable cyans, then to unrepresentable blues, and then finally converges close to the sRGB blue primary again once the water is very deep and dark. 
A beautiful blue bay
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Yuliya Komska @ykomska.bsky.social · 05/06/2026
By Jim Benton
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