iiinova — where your digital self keeps evolving

Reposted by Melike Lakadamyali

Estibaliz Gómez de Mariscal, PhD @gomez-mariscal.bsky.social · 18/09/2026

🚨Our work #ReScale4DL: balancing pixel and contextual information for enhanced bioimage segmentation, with @henriqueslab.bsky.social is out today!🚀 www.nature.com/articles/s41... ReScale4DL links key concepts in DL (receptive fields)+microscopy (resolution) so they can work #bettertogether😉 Threat👇

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Melike Lakadamyali @melikel.bsky.social · 01/09/2026

Nanoscale Approaches to Biology is excited to be hosting this special event during BPS emerging science week with an excellent lineup of speakers. Please register and join us!

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Reposted by Melike Lakadamyali

Diez Lab @ TU Dresden @stefandiezlab.bsky.social · 19/07/2026

🔬 #JobAlert Interested in doing a PhD with us in #SyntheticBiology on the Reconstitution of Oscillatory Microtubule-Motor Systems? Check shorturl.at/wis5P (note the eligibility criteria) or/and get in touch with us shorturl.at/WmgOD. Deadline: 31 July 2026 #WeAreHiring #AcademicJobs #ScienceJobs

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Melike Lakadamyali @melikel.bsky.social · 13/07/2026

Very proud of Dr. Kim on a stellar defense. This is a bittersweet moment for the lab as she will be missed. But a bright future awaits her in her new career and we all wish her the best of luck. Her contributions will continue to make an impact in our science and the field for many years to come!

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Reposted by Melike Lakadamyali

Abby Buchwalter @abbybuch.bsky.social · 21/06/2026

After some good funding news, we are hiring! Looking for a postdoc to join our team and lead our explorations into transposon repression by the nuclear lamina. Check out the full ad on our lab website at buchwalter-lab.github.io/postdoc-ad.pdf + contact me to learn more!

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Reposted by Melike Lakadamyali

Max Planck Institute for Medical Research @mpi-mr.bsky.social · 09/06/2026

🤩We're really looking forward to our next Rudolf Mößbauer Colloquium with Melike Lakadamyali @melikel.bsky.social from @upenn.edu University of Pennsylvania School of Medicine! 🚀🔬 #mmimr #maxplanck #rmc #scientifictalks #superresolution #imaging

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Reposted by Melike Lakadamyali

Journal of Cell Biology @jcb.org · 01/06/2026

Heterogeneity of late #endosome/#lysosomes shown by multiplexed DNA-PAINT imaging. Quantitative pipeline developed by Charles Bond, Melike Lakadamyali @melikel.bsky.social and colleagues: rupress.org/jcb/article/... 📕 Part of #Lysosomes 2026: rupress.org/jcb/collecti...

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Melike Lakadamyali @melikel.bsky.social · 18/05/2026

Proud PI moment. Adriana’s thesis work in my lab was tour de force and I am so happy and proud to have had the privilege of hooding her today.

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Sinem Saka @sinemsaka.bsky.social · 27/04/2026

Cells are not just bags of molecules. Function depends on spatial interactions: RNAs and/or proteins come together with interaction partners to drive regulation and function. In our new preprint, we introduce ProPER, a novel method for in situ proximity detection. Preprint: tinyurl.com/muju86s6

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Sonja Schmid @scisonja.bsky.social · 20/04/2026

Don't miss the #GordonConference on 𝑺𝒊𝒏𝒈𝒍𝒆-𝒎𝒐𝒍𝒆𝒄𝒖𝒍𝒆 𝑨𝒑𝒑𝒓𝒐𝒂𝒄𝒉𝒆𝒔 𝒕𝒐 𝑩𝒊𝒐𝒍𝒐𝒈𝒚, organized by #KevinWelsher & me: ⏰ June 28 - July 3, 2026 🌍 in the Swiss Alpes (✈️ Geneva) ✅ APPLY now: deadline May 31. We're 75% booked: register today & be there! 🙌 🕳️ 🧬🧪🧫 🔬🟩🟥🟩🟥🏋️‍♀️💥🪤 🍩 ... you get it... 😁

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Ulrike Boehm @ulrikeboehm.bsky.social · 01/04/2026

What if cells have undiscovered methods for managing their internal logistics? Our recent work (@cathygalbraith.bsky.social, James A. Galbraith, @sciencethecat.bsky.social & myself) challenges existing views on intracellular transportation 🔗 lnkd.in/dhMDgY5Q

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Reposted by Melike Lakadamyali

Max Planck Institute of Immunobiology and Epigenetics @mpi-ie.bsky.social · 27/03/2026

🚨 Postdoc in 3D genome architecture – join the @jumanaaha.bsky.social lab at the MPI-IE, Freiburg (🇩🇪) The wonderful lab of Jumana AlHaj Abed is pushing the limits of how chromosomes fold and interaction – and we need someone who can code, image, & think across scales. Apply here: s.gwdg.de/9c8838

Illustration of a fly and cellular structures connected by red and black thread-like lines inside a circle with a blue dot labeled 'TF' and text 'AlHaj Abed LAB' and 'Postdoctoral Researcher (m/w/d) Max Planck Institute of Immunobiology & Epigenetics'

Text listing tasks in AlHaj Abed lab including Hi-C and Micro-C analysis, adapting multi-way contact genomic tools for Drosophila, building visualization framework for Pore-C data, image analysis, and programming in R and/or Python

Text listing reasons to appreciate the Max Planck Institute in Freiburg including collaborative culture, core facilities, grants, scientific network, international diversity, public benefits, family support, relocation service, social life, and location, with a website link

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Reposted by Melike Lakadamyali

Sinem Saka @sinemsaka.bsky.social · 20/03/2026

Spectral multiplexing is typically limited to 4-5 channels. Our new preprint introduces a framework that utilizes DNA barcoding and signal tuning to enable robust spectral unmixing and ground-truth benchmarking to achieve 15-plex subcellular profiling without cycling www.biorxiv.org/content/10.6...

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Mir Lab @mirlab.bsky.social · 20/03/2026

@mukherja.bsky.social work on RNAPII clusters is in print today: www.nature.com/articles/s41... Congrats! TLDR: RNAPII clusters represent transcriptonally engaged molecules at single genes, not super-stochiometric assemblies. Please check it out and see the the thread below for a summary.

nature.com

A single cluster of RNA Polymerase II molecules is stably associated with active genes - Nature Communications

Live molecular-scale imaging in fly embryos shows that a single RNA Polymerase II cluster stays bound to active genes during transcription. Cluster formation requires initiation, and intensity represe...

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Reposted by Melike Lakadamyali

Diana Voss @dianavoss.bsky.social · 26/02/2026

Baby KJ update! 🧪 He's looking so good now 🥹 Hope this little guy continues to thrive and that the team at CHOP gets to save more kids like him.🫶 youtu.be/dMY-nYMeis4?...

youtu.be

Baby KJ One Year Later: Gene-Editing Breakthrough Update

YouTube video by The Children's Hospital of Philadelphia

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Max Planck Institute of Immunobiology and Epigenetics @mpi-ie.bsky.social · 06/02/2026

This Friday (today), we’re pleased to welcome Melike Lakadamyali (@melikel.bsky.social) from @upenn.edu. If you are interested in Super resolution microscopy, cytoplasmic and nuclear organization with a focus on biophysics, then do not miss Prof. Lakadamyali talk in our lecture hall at 13:00. 🤗

Seminar announcement for Max Planck Seminar Freiburg titled 'Super-resolution imaging of chromatin in health and disease' with date, time, location, and speaker Melike Lakadamyali from University of Pennsylvania Philadelphia USA

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Reposted by Melike Lakadamyali

FocalPlane @focalplane.bsky.social · 29/01/2026

Melike Lakadamyali @melikel.bsky.social, Jérôme Solon and Manuel Mendoza @longchrom.bsky.social share the behind the paper story of their research interrogating how chromosome compaction scales with cell size using a combination of live confocal microscopy and 3D STORM.

focalplane.biologists.com

Seeing Chromatin Scaling with Cell Size, from Interphase to Mitosis - FocalPlane

Seeing Chromatin Scaling with Cell Size, from Interphase to Mitosis -

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Reposted by Melike Lakadamyali

Manuel Mendoza @longchrom.bsky.social · 26/01/2026

Thanks to @focalplane.bsky.social for the invitation to highlight our recent @biophysj.bsky.social paper! With @melikel.bsky.social and Jérôme Solon, we combined super-resolution and live imaging to connect interphase chromatin organisation to mitotic chromosome compaction across cell sizes.

focalplane.biologists.com

Seeing Chromatin Scaling with Cell Size, from Interphase to Mitosis - FocalPlane

Seeing Chromatin Scaling with Cell Size, from Interphase to Mitosis -

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Reposted by Melike Lakadamyali

EMBL @embl.org · 22/01/2026

EMBL is deeply saddened by the passing of our Interim Director General Peer Bork, a pioneering scientist who left an indelible imprint on life science research in Europe and beyond. We extend our deepest condolences to his family, friends, and colleagues. www.embl.org/news/people-...

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Gautam Dey @gautamdey.bsky.social · 27/11/2025

So proud to watch Jana turn a side quest into an entire research programme. Couldn’t imagine a more well-deserved outcome. 😍 The mighty yeast reveals what we believe are general principles of centromere evolution! Behind the curtain: communities.springernature.com/posts/counti... #MEvoSky 🧪🌎

communities.springernature.com

Counting Chromosomes: The Simple Idea That Unlocked the Rules Behind Centromere Evolution

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Ulrike Endesfelder @uendesfelder.bsky.social · 22/10/2025

Last call for Les Houches! Apply now or never! ;) (ok, in 2 years again then) and share with your friends.

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Jean-Yves Tinevez @jytinevez.bsky.social · 07/10/2025

Job alert! We are looking for a bioimage analysis to work in an image analysis core facility in beautiful Paris. Can I ask you to share this opportunity with your networks? See also on the forum: forum.image.sc/t/research-e...

forum.image.sc

Research engineer in Bioimage Analysis for the researchers of the inIdEx FORMULA

Hi all We are looking for a bioimage analysis to work in an image analysis core facility in beautiful Paris. Can I ask you to share this opportunity with your networks? The position is in the Instit...

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Biophysical Society @biophysicalsoc.bsky.social · 24/09/2025

Erdinc Sezgin to Receive 2026 Early Independent Career Award www.biophysics.org/news-room/er...

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Biophysical Society @biophysicalsoc.bsky.social · 24/09/2025

Jie Xiao to Receive 2026 Carolyn Cohen Innovation Award www.biophysics.org/news-room/ji...

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Biophysical Society @biophysicalsoc.bsky.social · 24/09/2025

Sarah Veatch to Receive 2026 Agnes Pockels Award in Lipids and Membrane Biophysics buff.ly/AdSMhCT

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Biophysical Society @biophysicalsoc.bsky.social · 24/09/2025

Cornelis (Cees) Dekker to Receive the 2026 Kazuhiko Kinosita Award in Single-Molecule Biophysics buff.ly/fIexyZu

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Ulrike Endesfelder @uendesfelder.bsky.social · 12/09/2025

Please share: The application for Les Houches is open (until Oct 31) fluorescenceleshouches.wordpress.com *This is for you, if you ever wanted to learn all about fluorescence markers & how to apply them for your biological research!* PS: no fees this year, you just need to get there, that's all!

fluorescenceleshouches.wordpress.com

French-German WE-Heraeus-Seminar "Fluorescence markers for advanced microscopy : From photophysics to biology - 2026"

March 15-20 2026, Les Houches, France

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Prevedel Lab @prevedel-lab.bsky.social · 12/09/2025

@embl.org Heidelberg is looking for a new Head of Scientific Instrumentation! This is an exciting opportunity at the interface between scientific research and technology development, overseeing our mechanical and electronic workshops! embl.wd103.myworkdayjobs.com/en-US/EMBL/d...

embl.wd103.myworkdayjobs.com

Head of Scientific Instrumentation Workshops

EMBL is a world leader in scientific research and at the forefront in the development of cutting-edge technologies. It operates across six sites in Heidelberg (headquarters), Barcelona, Cambridge, Gre...

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Sara Wickstrom @sarawickstrom.bsky.social · 12/09/2025

My lab @mpi-muenster.bsky.social is looking for a computational biologist with a passion for imaging and spatial biology. A staff scientist position with long-term perspective! Apply and spread the word 🙏 jobs.mpi-muenster.mpg.de/jobposting/0...

jobs.mpi-muenster.mpg.de

Computational image analyst (m/f/d)

The Max Planck Institute for Molecular Biomedicine in Münster, Germany, has an opening for a

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Eric Joyce @ericjoyce.bsky.social · 14/08/2025

🚨New preprint from the lab🚨 🧬 What keeps certain chromatin domains anchored at the nuclear periphery? Our new genome-wide HiDRO screen uncovers a key role for RNA-binding protein hnRNPK. www.biorxiv.org/content/10.1...

biorxiv.org

Mechanistic and Epigenetic Partitioning of Lamina-Associated Chromatin Revealed by a Genome-Wide Imaging Screen

The nuclear periphery is a key site for heterochromatin organization in eukaryotic cells, where lamina-associated domains (LADs) promote transcriptional repression and genome stability. Despite their ...

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Reposted by Melike Lakadamyali

Eileen Furlong @eileen-furlong.bsky.social · 30/07/2025

To all post-docs: The Genome Biology dept ‪@embl.org has an Independent faculty position. Fantastic place to set up your lab –great package: core funding, fantastic Ph.D. students, cutting edge core facilities & great colleagues. Closing date Sept 19th embl.wd103.myworkdayjobs.com/en-US/EMBL/j...

embl.wd103.myworkdayjobs.com

Group Leader - Genome Biology Unit

Are you ready to lead groundbreaking research in Genome Biology? Join us at EMBL! We are seeking a motivated scientist to lead an independent research group addressing exciting and original biological...

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Gautam Dey @gautamdey.bsky.social · 07/08/2025

Want to acquire #ExM images like this and help us understand the true extent of cytoskeletal diversity across the tree of life? This position might be for you! embl.wd103.myworkdayjobs.com/en-US/EMBL/j... With @dudinlab.bsky.social @embl.org @biology-unige.bsky.social @moorefound.bsky.social

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Melike Lakadamyali @melikel.bsky.social · 09/08/2025

I’m excited to start my sabbatical at the EMBL in beautiful Heidelberg hosted by @sinemsaka.bsky.social Looking forward to learning more about DNA barcoding technologies, spatial omics, MINFLUX and more. Really excited about the exchange with all the amazing scientists at EMBL!

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Sonja Schmid @scisonja.bsky.social · 31/07/2025

💥 We have 3 positions open in my lab in Basel, Switzerland🇨🇭: #nanopores #smFRET #biomolecular #dynamics #singleMolecules We’re looking for talented & ambitious new colleagues enthusiastic about biomolecular dynamics & single-molecule tech. Please share broadly, thank you!🤝 schmid.chemie.unibas.ch

schmid.chemie.unibas.ch

Home | Research Group Schmid | University of Basel

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Ellenberg Lab @ellenberglab.bsky.social · 21/07/2025

Our new non-denaturing nanoscale 3D DNA tracing technology provides single-cell (and sister-chromatid specific!) readout of chromatin structure with 10kb genomic resolution - Check it out! www.nature.com/articles/s41... Congratulations to Kai and Oyvind!!

nature.com

Nanoscale 3D DNA tracing in non-denatured cells resolves the Cohesin-dependent loop architecture of the genome in situ - Nature Communications

A nanoscale 3D DNA tracing workflow visualizes Cohesin-dependent loops in single, structurally well-preserved cells. Computer simulations based on the tracing data give further insight into how Cohesi...

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Ricardo Henriques @henriqueslab.bsky.social · 10/07/2025

🚨Join us! We're soon opening 3 postdoctoral positions in #AIDrivenBiology. Seeking biologists (especially microbiology and infection biology), computer scientists, and microscopy developers. Ideal candidates are those eager to use or develop next-gen tech for cell biology. Get in touch (DM/email)

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Felix Campelo @felixmendu.bsky.social · 04/07/2025

Announcing a new @embo.org Workshop on "Intracellular mechanics and organelle mechanobiology" that we are organizing with Michael Krieg and Verena Ruprecht at @icfo.eu (Barcelona) on 16-20 February, 2026. Please, repost and spread the word! 🙏 #EMBOmechanobio meetings.embo.org/event/26-org...

meetings.embo.org

Intracellular mechanics and organelle mechanobiology

Mechanobiology is an interdisciplinary field that emerges at the cross-section of biology, physics and engineering. It aims to understand how living cells, tissues and animals sense and respond to me…

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Reposted by Melike Lakadamyali

Joel Boerckel @jboerckel.bsky.social · 19/06/2025

Out latest preprint, from @cpane94.bsky.social in the lab, is out today! Maternal exercise rescues fetal akinesia-impaired joint and bone development. www.biorxiv.org/content/10.1... So excited for this one - a wonderful collab with Niamh Nowlan, supported by the US-Ireland Partnership Programme ❤️

“Supervised” maternal wheel running exercise from E13.5-E16.5

Maternal exercise induces passive movements that rescue the effects of fetal akinesia on forelimb bone and joint development.

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Ulrike Endesfelder @uendesfelder.bsky.social · 12/06/2025

👇 Reminder on deadlines for i) early bird, ii) free child care option and iii) abstract talk selection! 👇

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Heilemann Lab @heilemannlab.bsky.social · 31/05/2025

👉🏻 so glad to see this work out now ... a masterpiece conceived, led and driven by 👉🏻 Christoph Spahn 👏@michriscopy.bsky.social (🚨 #NewPI) and with great collaborations 🙏 @henriqueslab.bsky.social @seamusholden.bsky.social @gomez-mariscal.bsky.social

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Fyodor Urnov @urnov.bsky.social · 04/06/2025

Here: Baby KJ at home with his mom Nicole. This really happened, folks. Hundreds of people from 8 organizations (led by Rebecca Ahrens-nicklas and Kiran Musunuru) came together to make a bespoke gene editor for this kiddo. He was once in the 7th percentile of body weight. Look at him now! ❤️

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Carolyn Johnson @carolynyjohnson.bsky.social · 03/06/2025

In case you needed a smile this Tuesday: 10-month-old baby KJ, who received a bespoke gene-editing therapy after a six month scientific sprint - "graduated" from the hospital @childrensphila.bsky.social today and went HOME! YAY SCIENCE! Here's his story: wapo.st/451ZQjT

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Golnaz Vahedi @vahedilab.bsky.social · 02/06/2025

🚨 New #preprint alert! We're excited to share our latest work: "Single-Allele Chromatin Tracing Reveals Genomic Clustering of Paralogous Transcription Factors as a Mechanism for Developmental Robustness in T Cells"🔗 tinyurl.com/4ve26tbd

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Sinem Saka @sinemsaka.bsky.social · 31/05/2025

We are happy to participate in the ARISE program and have a range of collaborative opportunities for various backgrounds including biochemistry, imaging, omics or lab automation. Get in touch if interested!

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Reposted by Melike Lakadamyali

Emmanuel Margeat @emmanuelmargeat.bsky.social · 26/05/2025

Our invited speakers : - Dominique Bourgeois - Johannes Broichhagen - Peter Dahlberg - Joerg Enderlein @joergenderlein.bsky.social - Ulrike Endesfelder @uendesfelder.bsky.social - Michelle Frei @michellefrei17.bsky.social - Dorus Gadella - Viktorija Glembocykte @glembockyte.bsky.social ../..

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