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Selma Masri

@masrilab.bsky.social
217 followers 196 following 22 posts

Associate Professor @UC Irvine studying how circadian clocks impact immunity, metabolism, stemness, and cancer. Obsessed with wine and my plants. masrilaboratory.com

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Reposted by Selma Masri
Cosimo Commisso @cosimocommisso.bsky.social · 24/07/2025
Excited to share work published in @cp-cancercell.bsky.social by @yijuan.bsky.social showing that macropinocytosis inhibition drives myCAF-to-iCAF conversion, enhancing therapeutic responses in pancreatic cancer. Thank you to our collaborators that contributed! www.sciencedirect.com/science/arti...
sciencedirect.com
Macropinocytosis maintains CAF subtype identity under metabolic stress in pancreatic cancer
Pancreatic ductal adenocarcinoma (PDAC) tumors are glutamine deficient, and both tumor cells and cancer-associated fibroblasts (CAFs) rely on this ami…
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Reposted by Selma Masri
Chrystal Starbird @drstarbird.bsky.social · 15/07/2025
"Nature has learnt that … some staff members are screening candidates’ social-media presences to check whether they have expressed negative views about the Trump administration or been involved in diversity, equity and inclusion (DEI) efforts … at their institutions." www.nature.com/articles/d41...
nature.com
Exclusive: NIH to dismiss dozens of grant reviewers to align with Trump priorities
The move would undo years of work, leaving advisory councils understaffed, and without the full expertise needed for reviews.
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Reposted by Selma Masri
Jeremy Berg @jeremymberg.bsky.social · 25/06/2025
Science story about termination of terminations... www.science.org/content/arti...
science.org
Following court order, NIH ceases new terminations of politically sensitive grants
After a judge told agency to restore hundreds of killed grants, NIH backs off plans to cancel more existing projects
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Nick Pannunzio @pannunziolab.bsky.social · 24/06/2025
A number of firsts this year including my first time participating in commencement @ucirvine.bsky.social and hooding my first 2 graduate students that have earned their PhDs!! Congratulations Valeria and Melissa! You are both amazing and this is only the beginning! 💪🧬🧪🦸‍♀️🦸‍♀️
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Jeremy Berg @jeremymberg.bsky.social · 18/06/2025
The findings at the recent trial and today's Columbia chaos is pushing me to the edge. I just sent the following email...
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Reposted by Selma Masri
Jeremy Berg @jeremymberg.bsky.social · 09/06/2025
Here is a link you can blast out to all of your networks to ask them to consider signing on in support of our NIH heroes. actionnetwork.org/forms/add-na... We are at 5000 folks who have signed on. But we can do better Only for people who have ever been sick or knows someone who has been.
actionnetwork.org
ADD YOUR NAME: Sign the Open Letter in Support of NIH Staff
Join the courageous and committed National Institutes of Health (NIH) public servants by adding your name now.
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Selma Masri @masrilab.bsky.social · 09/06/2025
Looking forward to sharing our recent work at #SLEEP2025! Circadian Medicine session starting in about an hour and I’ll be discussing approaches to timing cancer immunotherapy. See you there!
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Reposted by Selma Masri
Anne Fausto-Sterling @birdlady.bsky.social · 06/06/2025
race does not equal genes www.statnews.com/2025/06/05/n...
statnews.com
Massive NIH study challenges use of race as a proxy for genetic ancestry in research
A large government study shows that Americans’ self-reported race is a poor proxy for their genetic ancestry.
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Hurley Lab @jenniferhurleylab.bsky.social · 30/05/2025
Thanks to @npr.org and the Shortwave podcast for covering circadian research! It was very cool to be on the podcast and on All Things Considered. And Kudos to Chris Hall for the exciting work. www.npr.org/2025/05/29/n... www.npr.org/2025/05/30/1...
npr.org
This week in science: hawks hunting, infrared contacts and immunity through the day
Berly McCoy and Regina Barber of Short Wave talk about a hawk's clever hunting strategy, contacts that allow wearers to see infrared light, and how immunity varies during the day.
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Nick Pannunzio @pannunziolab.bsky.social · 28/05/2025
Check out our latest story @natcancer.nature.com co-led with @masrilab.bsky.social that reviews how the circadian clock intersects several aspects of cancer biology. Excited to be part of this collaborative team effort to understand impacts on DNA repair, early onset cancer, and cancer treatment 💪🧬🕔
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Selma Masri @masrilab.bsky.social · 27/05/2025
Super happy to share our latest in @natcancer.nature.com co-led by @pannunziolab.bsky.social! We review the complex role of the circadian clock in genome integrity, DNA repair, immunity, metabolism, and cancer with a specific focus on early-onset cancer. Check it out! www.nature.com/articles/s43...
nature.com
The diverse roles of the circadian clock in cancer - Nature Cancer
Masri and colleagues review the latest studies on the influence of circadian rhythms in cancer biology, discussing possible connections between chronobiology and cancer prevention and treatment.
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Tallie Z Baram @talliezee.bsky.social · 16/05/2025
Celebrating UCI school of medicine graduate students 🧪🧠 . You are the future of #science @ucirvine.bsky.social @cnlm.bsky.social @neurohoke.bsky.social
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Reposted by Selma Masri
Needhi Bhalla 💅🏽 @needhibhalla.bsky.social · 15/05/2025
I just emailed my state representatives to support Newsom's new budget for UC. If you agree that this economic and social engine for California needs robust state support, please join me. universityofcalifornia.quorum.us/campaign/sta...
universityofcalifornia.quorum.us
Time for Action!
Urge legislators to fund UC!
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Claudio Cantù @claudiocantu81.bsky.social · 12/05/2025
We had previously shown that TBX3 and #WNT cooperate in limb #DevBio We now have a shocking finding, just published in @pnas.org TBX3 physically engages with β-catenin to drive metastasis genes in #ColorectalCancer (CRC) www.pnas.org/doi/epub/10....
pnas.org
The developmental factor TBX3 engages with the Wnt/β-catenin transcriptional complex in colorectal cancer to regulate metastasis genes
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Pierfrancesco Pagella @ppagella86.bsky.social · 13/05/2025
Fresh out of press: our new chapter on the TBX3/WNT liaison, and how it drives metastasis-related genes expression in colorectal cancer, out on @pnas.org Enjoy the “bluetorial” by @claudiocantu81.bsky.social below! 👇🏼 #WNT #CRC @liu.se www.pnas.org/doi/10.1073/...
pnas.org
PNAS
Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...
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Reposted by Selma Masri
Cosimo Commisso @cosimocommisso.bsky.social · 11/05/2025
New preprint! 🧓⚡️ Aging drives immune exclusion & metastasis in PDAC by rewiring the tumor stroma. Young CAFs ♻️ rejuvenate the aged microenvironment & restore immune infiltration. Read: www.biorxiv.org/content/10.1... #PDAC #Aging #TumorMicroenvironment #Preprint
biorxiv.org
The Aging Microenvironment as a Determinant of Immune Exclusion and Metastatic Fate in Pancreatic Cancer
Aging is a critical yet understudied determinant in pancreatic ductal adenocarcinoma (PDAC). Despite a strong epidemiological association with age, conventional PDAC preclinical models fail to capture...
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Selma Masri @masrilab.bsky.social · 29/04/2025
Just watched this episode. John Oliver did an outstanding job breaking everything down, even what indirects costs are! It’s our job to get all this information out, especially to inform the general public. This needs to stop. Now.
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Jeremy Berg @jeremymberg.bsky.social · 25/04/2025
Sunday TV viewing...More to come later Lead story about NIH... www.paramountpressexpress.com/cbs-news-and...
paramountpressexpress.com
Paramount Press Express | “60 MINUTES” LISTINGS FOR SUNDAY, APRIL 27
Airs 7:00-8:00 PM, ET/ PT on the CBS Television Network NIH – In its ongoing mission to shrink the federal government, the Trump administration has cut
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Science Magazine @science.org · 23/04/2025
President Donald Trump’s administration appears to be killing much, if not all, of a historic initiative that was the first, and is still the largest, National Institutes of Health effort centered on the health needs of women. scim.ag/4jLeLTJ
scim.ag
NIH cancels its first and largest study centered on women
The Women’s Health Initiative has produced numerous influential findings
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Ashani Weeraratna @ashi-w.bsky.social · 22/04/2025
This breaks my heart in ways I can’t quite describe.
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Jeremy Berg @jeremymberg.bsky.social · 21/04/2025
New STAT story about the possible new NIH grants terms and conditions www.statnews.com/2025/04/21/t...
statnews.com
NIH moving to ban all future grants to universities with DEI programs or Israel boycotts, document suggests
NIH appears to be preparing to prohibit the awarding of new grants to institutions that have DEI programs or boycott Israeli companies
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Joanna Chiu @joanna-chiu.bsky.social · 19/04/2025
www.ucdavis.edu/research/lab... @ucdavis.bsky.social @ucdavishealth.bsky.social @ucdavisplants.bsky.social @ucdaviscns.bsky.social @ucdavispsych.bsky.social
ucdavis.edu
From Labs to Lives
UC Davis researchers describe the impact of their work and the life-altering consequences if federal funding for medical research were reduced or eliminated.
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Jeremy Berg @jeremymberg.bsky.social · 19/04/2025
STAT story about freezing all payments to Columbia, Harvard, Brown, Northwestern, Cornell, and Cornell-Weill Medicine. www.statnews.com/2025/04/18/n...
statnews.com
NIH said to have halted awarding of new grants to top universities
Universities whose NIH funding has been frozen may face further strain as the agency holds off awarding new grants to at least a half dozen of them, according to an internal email.
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NPR @npr.org · 18/04/2025
A presidential effort to revoke Harvard University's tax-exempt status could run up against a number of challenges, including violating federal law.
npr.org
History shows revoking Harvard's tax status won't be easy — or fast
A presidential effort to revoke Harvard University's tax-exempt status could run up against a number of challenges, including violating federal law.
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Nick Pannunzio @pannunziolab.bsky.social · 19/04/2025
The cast and crew of Pannunzio Lab season 6! Despite everything going on we continue to grow and be productive. Their excitement about science is contagious. These are the people that keep me coming in every day 💪🫀🧬
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Alice Callahan @alicecallahan.bsky.social · 16/04/2025
My story about @kevinh-phd.bsky.social, nutrition and metabolism scientist at N.I.H., who felt compelled to take early retirement after experiencing censorship of his work under the new administration. www.nytimes.com/2025/04/16/w...
nytimes.com
Leading Nutrition Scientist Departs N.I.H., Citing Censorship (Gift Article)
Kevin Hall said his work on ultraprocessed foods has been “hobbled” under the Trump administration. Scientists have been raising such concerns for months.
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Reposted by Selma Masri
Rémi Buisson @buissonlab.bsky.social · 16/04/2025
Today, we report that APOBEC3B targets unprotected single-stranded DNA at replication forks upon ATR inhibition, triggering a reaction cascade involving UNG2 and APE1 that leads to fork collapse and hyperactivation of PARP1, causing replication catastrophe. www.science.org/doi/10.1126/...
science.org
Mechanism of DNA replication fork breakage and PARP1 hyperactivation during replication catastrophe
Upon ATR inhibition, APOBEC3B targets unprotected single-stranded DNA at replication forks, leading to fork breakage.
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Reposted by Selma Masri
Rachel Maddow @maddow.bsky.social · 15/04/2025
"After nearly five hours, he and his wife were released. They are now pursuing legal action. "It's not about the immigrants," his sister, told NBC10 Boston. "It's coming to us Americans, and it's going to go after all of us." www.nbcboston.com/news/politic...
nbcboston.com
‘Treated like a criminal': US citizen says he was detained returning from Canada
Bachir Atallah, a real estate attorney from New Hampshire, says he and his wife, Jessica Fakhri, were stopped crossing from Canada into Vermont
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Needhi Bhalla 💅🏽 @needhibhalla.bsky.social · 08/04/2025
If a student you know received an honorable mention for the NSF GRFP, encourage them to contact their Congressional representatives! 🧪
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Eliza Bliss-Moreau @eblissmoreau.bsky.social · 07/04/2025
@ucdavis.bsky.social senior admin, I sincerely hope y’all a robust response to this planned.
kcra.com
Trump administration revokes visas for 12 international students at UC Davis, chancellor says
The Trump administration has revoked student visas for 12 international students at UC Davis without explanation, the university’s chancellor said on Saturday.
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Dheepa Sundaram, PhD (she/her) @themodsisyphus.bsky.social · 06/04/2025
They are now estimating 2.3 million across the country. Keep it going folks. #handsoff #50501protests
Images of protests and crowds across the country. 

HANDSOFF APRIL 5TH 2025
BOSTON
NEW YORK
CHICAGO
PORTLAND
SAN FRANCISCO
SAN DIEGO
IDAHO
UTAH
OAKLAND
(AND SOOOO MANY MORE!)
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Allison Gill @muellershewrote.com · 03/04/2025
I'm no good with patterns. Can someone help me out here?
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Jeremy Berg @jeremymberg.bsky.social · 04/04/2025
Temporary restraining order issued last night for the public health-related lawsuit against HHS on Tuesday) www.nytimes.com/2025/04/03/u...
nytimes.com
Judge Blocks H.H.S. From Terminating $11 Billion in Public Health Grants (Gift Article)
A coalition of states sued over the Trump administration’s unexpected move to cut off the funds, which they said imperiled everything from childhood vaccination programs to opioid addiction treatment.
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Chrystal Starbird @drstarbird.bsky.social · 02/04/2025
Finally got the notice. Very sad day for the MOSAIC program that supported some of the most amazing scientists I know, as well as some of the awesome people on my lab.
Letter from the NIH indicating that my grant has been terminated (though it seems we can keep the remaining funds for this year?)
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Sen. Cory Booker @booker.senate.gov · 02/04/2025
After getting some rest, I am in awe of everyone who continues to lift their voice and speak out. This is a moment for our country, and we must make a choice about the America we want to be.
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Selma Masri @masrilab.bsky.social · 01/04/2025
Please vote and support our work @ucirvine.bsky.social!! @statnews.com
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Selma Masri @masrilab.bsky.social · 27/03/2025
Please vote!! Please help us send @ucirvine.bsky.social to the finals of #STATMadness @statnews.com
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Selma Masri @masrilab.bsky.social · 27/03/2025
Please vote!! Please help us send @ucirvine.bsky.social to the finals of #STATMadness @statnews.com
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Selma Masri @masrilab.bsky.social · 27/03/2025
We need your support! @ucirvine.bsky.social has made it to the semifinals in #STATMadness @statnews.com. We need your support to send us to the finals!!! Let’s goooooo!!!! www.statnews.com/feature/stat...
statnews.com
2025 STAT Madness
2025 bracket Welcome to STAT Madness, a bracket-style contest to find the best innovation in science and medicine. Explore groundbreaking innovations from
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Reposted by Selma Masri
Jeremy Berg @jeremymberg.bsky.social · 25/03/2025
A teeny bit of information officially from NIH... nexus.od.nih.gov/all/2025/03/...
nexus.od.nih.gov
Implementation of New Initiatives and Policies Page Now Available
We have posted an Implementation of New Initiatives and Policies page on the public NIH Grants & Funding Website to pull together the latest information on recent and upcoming changes that impact appl...
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Selma Masri @masrilab.bsky.social · 24/03/2025
Please vote and send us to the next round!!! @ucirvine.bsky.social
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Jeremy Berg @jeremymberg.bsky.social · 23/03/2025
ATTENTION If anyone has any experience with appealing terminated grants (either the process or successful strategies 😀), please DM me. THANK YOU!
media.tenor.com
a hello kitty sticker that says `` let me know '' .
ALT: a hello kitty sticker that says `` let me know '' .
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Jameel Jaffer @jameeljaffer.bsky.social · 21/03/2025
A sad day for Columbia and for our democracy. "Additionally the school believed there was considerable overlap between needed campus changes and Trump’s demands" has got to be one of the most depressing sentences ever written. www.wsj.com/us-news/educ...
wsj.com
Exclusive | Columbia Yields to Trump in Battle Over Federal Funding
Columbia’s agreement is a significant moment in the intensifying battle between Trump and elite universities.
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Annika Barber @annikabarber.bsky.social · 17/03/2025
Yay: Most postponed study sections have been rescheduled at this point. Yikes: To do this, CSR has scheduled *289* study sections from 03/24-05/16/2025. For comparison, there were only 96 study sections from 3/24-5/17/2024. And NIH still plans to RIF more staff. docs.google.com/spreadsheets...
docs.google.com
2025 Study section tracking
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AlphaFold Unofficial @alphafold.bsky.social · 15/03/2025
“Unless you're a tech billionaire, this is going to lead to a worse future for you and the people you care about. Expect AI to be unfair, discriminatory, unsafe, and deployed irresponsibly,” And the major AI companies in the U.S. are complying. We’re compiling lists. www.wired.com/story/ai-saf...
wired.com
Under Trump, AI Scientists Are Told to Remove ‘Ideological Bias’ From Powerful Models
A directive from the National Institute of Standards and Technology eliminates mention of “AI safety” and “AI fairness.”
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Selma Masri @masrilab.bsky.social · 14/03/2025
Looking forward to this!
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Annika Barber @annikabarber.bsky.social · 14/03/2025
Updated the NIH CSR study section tracking sheet to include meetings originally scheduled for 03/17-03/21. There are now over *two hundred* study sections that didn't meet as scheduled. Likely an undercount due to things I couldn't scrape orig date was removed. docs.google.com/spreadsheets...
docs.google.com
2025 Study section tracking
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Nick Pannunzio @pannunziolab.bsky.social · 13/03/2025
Calling on all Blueskies to help @masrilab.bsky.social by voting in the STAT Madness competition; a friendly competition for bragging rights. They've made it to round 2 and you can help them go all the way! Set up a free account and vote up to 5x per round! Go UCI! www.statnews.com/feature/stat...
statnews.com
2025 STAT Madness
2025 bracket Welcome to STAT Madness, a bracket-style contest to find the best innovation in science and medicine. Explore groundbreaking innovations from
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Igor Brodsky @brodskyigorlab.bsky.social · 13/03/2025
In 2024 NIH grant awards supported 407,782 jobs and $94.58 billion in new economic activity nationwide, the largest figure in the history of the report. www.forbes.com/sites/michae...
forbes.com
NIH Grants Fueled $95 Billion In FY 2024 Economic Activity, Finds New Report
National Institutes of Health grants generated almost $95 billion in economic activity nationwide in FY 2024 according to a new report by United for Medical Research.
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