In this population-based cohort study, Glynn et al. tested the contribution of childhood unpredictability to mental health outcomes in ~30,000 participants, examining the relative and additive roles o...

Researchers who live with serious mental illness or substance use disorders bring unique insight to psychiatric neuroscience, yet they remain underrepresented in the field. This paper calls for recogn...

Acute concurrent stresses provoke lasting, sex-dependent memory problems. Hokenson, Rodríguez-Acevedo, et al. find that high hippocampal estrogen levels in mice generate permissive chromatin states, allowing both adaptive plasticity and vulnerability to acute concurrent stresses. Stress vulnerability involves estrogen receptor (ER)α in males and ERβ in females.

Findings of UC Irvine-led study could lead to new ways of addressing PTSD, dementia

Acute concurrent stresses provoke lasting, sex-dependent memory problems. Hokenson, Rodríguez-Acevedo, et al. find that high hippocampal estrogen levels in mice generate permissive chromatin states, a...

In just 15 days, three powerful strikes have set the United States on the path to destroying its own scientific enterprise. Labs will…

Stigma is a frequently cited barrier to help-seeking for many with substance-related conditions. Common ways of describing individuals with such probl…