Reposted by Selma MasriCosimo Commisso @cosimocommisso.bsky.social · 24/07/2025Excited to share work published in @cp-cancercell.bsky.social by @yijuan.bsky.social showing that macropinocytosis inhibition drives myCAF-to-iCAF conversion, enhancing therapeutic responses in pancreatic cancer. Thank you to our collaborators that contributed! www.sciencedirect.com/science/arti...sciencedirect.comMacropinocytosis maintains CAF subtype identity under metabolic stress in pancreatic cancerPancreatic ductal adenocarcinoma (PDAC) tumors are glutamine deficient, and both tumor cells and cancer-associated fibroblasts (CAFs) rely on this ami… 2295
Reposted by Selma MasriChrystal Starbird @drstarbird.bsky.social · 15/07/2025"Nature has learnt that … some staff members are screening candidates’ social-media presences to check whether they have expressed negative views about the Trump administration or been involved in diversity, equity and inclusion (DEI) efforts … at their institutions." www.nature.com/articles/d41...nature.comExclusive: NIH to dismiss dozens of grant reviewers to align with Trump prioritiesThe move would undo years of work, leaving advisory councils understaffed, and without the full expertise needed for reviews. 021
Reposted by Selma MasriJeremy Berg @jeremymberg.bsky.social · 25/06/2025Science story about termination of terminations... www.science.org/content/arti...science.orgFollowing court order, NIH ceases new terminations of politically sensitive grantsAfter a judge told agency to restore hundreds of killed grants, NIH backs off plans to cancel more existing projects 24918
Reposted by Selma MasriNick Pannunzio @pannunziolab.bsky.social · 24/06/2025A number of firsts this year including my first time participating in commencement @ucirvine.bsky.social and hooding my first 2 graduate students that have earned their PhDs!! Congratulations Valeria and Melissa! You are both amazing and this is only the beginning! 💪🧬🧪🦸♀️🦸♀️ 071
Reposted by Selma MasriJeremy Berg @jeremymberg.bsky.social · 18/06/2025The findings at the recent trial and today's Columbia chaos is pushing me to the edge. I just sent the following email... 25518111
Reposted by Selma MasriJeremy Berg @jeremymberg.bsky.social · 09/06/2025Here is a link you can blast out to all of your networks to ask them to consider signing on in support of our NIH heroes. actionnetwork.org/forms/add-na... We are at 5000 folks who have signed on. But we can do better Only for people who have ever been sick or knows someone who has been.actionnetwork.orgADD YOUR NAME: Sign the Open Letter in Support of NIH StaffJoin the courageous and committed National Institutes of Health (NIH) public servants by adding your name now. 07454
Selma Masri @masrilab.bsky.social · 09/06/2025Looking forward to sharing our recent work at #SLEEP2025! Circadian Medicine session starting in about an hour and I’ll be discussing approaches to timing cancer immunotherapy. See you there! 051
Reposted by Selma MasriAnne Fausto-Sterling @birdlady.bsky.social · 06/06/2025race does not equal genes www.statnews.com/2025/06/05/n...statnews.comMassive NIH study challenges use of race as a proxy for genetic ancestry in researchA large government study shows that Americans’ self-reported race is a poor proxy for their genetic ancestry. 321588
Reposted by Selma MasriHurley Lab @jenniferhurleylab.bsky.social · 30/05/2025Thanks to @npr.org and the Shortwave podcast for covering circadian research! It was very cool to be on the podcast and on All Things Considered. And Kudos to Chris Hall for the exciting work. www.npr.org/2025/05/29/n... www.npr.org/2025/05/30/1...npr.orgThis week in science: hawks hunting, infrared contacts and immunity through the dayBerly McCoy and Regina Barber of Short Wave talk about a hawk's clever hunting strategy, contacts that allow wearers to see infrared light, and how immunity varies during the day. 0134
Reposted by Selma MasriNick Pannunzio @pannunziolab.bsky.social · 28/05/2025Check out our latest story @natcancer.nature.com co-led with @masrilab.bsky.social that reviews how the circadian clock intersects several aspects of cancer biology. Excited to be part of this collaborative team effort to understand impacts on DNA repair, early onset cancer, and cancer treatment 💪🧬🕔 052
Selma Masri @masrilab.bsky.social · 27/05/2025Congratulations to first author Bridget Fortin, a true rockstar! Also, a huge shout out to our phenomenal collaborators on this piece, @yincaoscd.bsky.social and Katja Lamia. This was a true team effort! 030
Selma Masri @masrilab.bsky.social · 27/05/2025Super happy to share our latest in @natcancer.nature.com co-led by @pannunziolab.bsky.social! We review the complex role of the circadian clock in genome integrity, DNA repair, immunity, metabolism, and cancer with a specific focus on early-onset cancer. Check it out! www.nature.com/articles/s43...nature.comThe diverse roles of the circadian clock in cancer - Nature CancerMasri and colleagues review the latest studies on the influence of circadian rhythms in cancer biology, discussing possible connections between chronobiology and cancer prevention and treatment. 1145
Reposted by Selma MasriTallie Z Baram @talliezee.bsky.social · 16/05/2025Celebrating UCI school of medicine graduate students 🧪🧠 . You are the future of #science @ucirvine.bsky.social @cnlm.bsky.social @neurohoke.bsky.social 0111
Reposted by Selma MasriNeedhi Bhalla 💅🏽 @needhibhalla.bsky.social · 15/05/2025I just emailed my state representatives to support Newsom's new budget for UC. If you agree that this economic and social engine for California needs robust state support, please join me. universityofcalifornia.quorum.us/campaign/sta...universityofcalifornia.quorum.usTime for Action!Urge legislators to fund UC! 01010
Reposted by Selma MasriClaudio Cantù @claudiocantu81.bsky.social · 12/05/2025We had previously shown that TBX3 and #WNT cooperate in limb #DevBio We now have a shocking finding, just published in @pnas.org TBX3 physically engages with β-catenin to drive metastasis genes in #ColorectalCancer (CRC) www.pnas.org/doi/epub/10....pnas.orgThe developmental factor TBX3 engages with the Wnt/β-catenin transcriptional complex in colorectal cancer to regulate metastasis genes 6359
Reposted by Selma MasriPierfrancesco Pagella @ppagella86.bsky.social · 13/05/2025Fresh out of press: our new chapter on the TBX3/WNT liaison, and how it drives metastasis-related genes expression in colorectal cancer, out on @pnas.org Enjoy the “bluetorial” by @claudiocantu81.bsky.social below! 👇🏼 #WNT #CRC @liu.se www.pnas.org/doi/10.1073/...pnas.orgPNASProceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans... 041
Reposted by Selma MasriCosimo Commisso @cosimocommisso.bsky.social · 11/05/2025New preprint! 🧓⚡️ Aging drives immune exclusion & metastasis in PDAC by rewiring the tumor stroma. Young CAFs ♻️ rejuvenate the aged microenvironment & restore immune infiltration. Read: www.biorxiv.org/content/10.1... #PDAC #Aging #TumorMicroenvironment #Preprintbiorxiv.orgThe Aging Microenvironment as a Determinant of Immune Exclusion and Metastatic Fate in Pancreatic CancerAging is a critical yet understudied determinant in pancreatic ductal adenocarcinoma (PDAC). Despite a strong epidemiological association with age, conventional PDAC preclinical models fail to capture... 2238
Selma Masri @masrilab.bsky.social · 29/04/2025Just watched this episode. John Oliver did an outstanding job breaking everything down, even what indirects costs are! It’s our job to get all this information out, especially to inform the general public. This needs to stop. Now. 161
Reposted by Selma MasriJeremy Berg @jeremymberg.bsky.social · 25/04/2025Sunday TV viewing...More to come later Lead story about NIH... www.paramountpressexpress.com/cbs-news-and...paramountpressexpress.comParamount Press Express | “60 MINUTES” LISTINGS FOR SUNDAY, APRIL 27Airs 7:00-8:00 PM, ET/ PT on the CBS Television Network NIH – In its ongoing mission to shrink the federal government, the Trump administration has cut 14113
Reposted by Selma MasriScience Magazine @science.org · 23/04/2025President Donald Trump’s administration appears to be killing much, if not all, of a historic initiative that was the first, and is still the largest, National Institutes of Health effort centered on the health needs of women. scim.ag/4jLeLTJscim.agNIH cancels its first and largest study centered on womenThe Women’s Health Initiative has produced numerous influential findings 1013677
Reposted by Selma MasriAshani Weeraratna @ashi-w.bsky.social · 22/04/2025This breaks my heart in ways I can’t quite describe. 0109
Reposted by Selma MasriJeremy Berg @jeremymberg.bsky.social · 21/04/2025New STAT story about the possible new NIH grants terms and conditions www.statnews.com/2025/04/21/t...statnews.comNIH moving to ban all future grants to universities with DEI programs or Israel boycotts, document suggestsNIH appears to be preparing to prohibit the awarding of new grants to institutions that have DEI programs or boycott Israeli companies 107265
Reposted by Selma MasriJoanna Chiu @joanna-chiu.bsky.social · 19/04/2025www.ucdavis.edu/research/lab... @ucdavis.bsky.social @ucdavishealth.bsky.social @ucdavisplants.bsky.social @ucdaviscns.bsky.social @ucdavispsych.bsky.socialucdavis.eduFrom Labs to LivesUC Davis researchers describe the impact of their work and the life-altering consequences if federal funding for medical research were reduced or eliminated. 062
Reposted by Selma MasriJeremy Berg @jeremymberg.bsky.social · 19/04/2025STAT story about freezing all payments to Columbia, Harvard, Brown, Northwestern, Cornell, and Cornell-Weill Medicine. www.statnews.com/2025/04/18/n...statnews.comNIH said to have halted awarding of new grants to top universitiesUniversities whose NIH funding has been frozen may face further strain as the agency holds off awarding new grants to at least a half dozen of them, according to an internal email. 412243
Reposted by Selma MasriNPR @npr.org · 18/04/2025A presidential effort to revoke Harvard University's tax-exempt status could run up against a number of challenges, including violating federal law.npr.orgHistory shows revoking Harvard's tax status won't be easy — or fastA presidential effort to revoke Harvard University's tax-exempt status could run up against a number of challenges, including violating federal law. 566156063312
Reposted by Selma MasriNick Pannunzio @pannunziolab.bsky.social · 19/04/2025The cast and crew of Pannunzio Lab season 6! Despite everything going on we continue to grow and be productive. Their excitement about science is contagious. These are the people that keep me coming in every day 💪🫀🧬 091
Reposted by Selma MasriAlice Callahan @alicecallahan.bsky.social · 16/04/2025My story about @kevinh-phd.bsky.social, nutrition and metabolism scientist at N.I.H., who felt compelled to take early retirement after experiencing censorship of his work under the new administration. www.nytimes.com/2025/04/16/w...nytimes.comLeading Nutrition Scientist Departs N.I.H., Citing Censorship (Gift Article)Kevin Hall said his work on ultraprocessed foods has been “hobbled” under the Trump administration. Scientists have been raising such concerns for months. 20728295
Reposted by Selma MasriRémi Buisson @buissonlab.bsky.social · 16/04/2025Today, we report that APOBEC3B targets unprotected single-stranded DNA at replication forks upon ATR inhibition, triggering a reaction cascade involving UNG2 and APE1 that leads to fork collapse and hyperactivation of PARP1, causing replication catastrophe. www.science.org/doi/10.1126/...science.orgMechanism of DNA replication fork breakage and PARP1 hyperactivation during replication catastropheUpon ATR inhibition, APOBEC3B targets unprotected single-stranded DNA at replication forks, leading to fork breakage. 1257
Reposted by Selma MasriRachel Maddow @maddow.bsky.social · 15/04/2025"After nearly five hours, he and his wife were released. They are now pursuing legal action. "It's not about the immigrants," his sister, told NBC10 Boston. "It's coming to us Americans, and it's going to go after all of us." www.nbcboston.com/news/politic...nbcboston.com‘Treated like a criminal': US citizen says he was detained returning from CanadaBachir Atallah, a real estate attorney from New Hampshire, says he and his wife, Jessica Fakhri, were stopped crossing from Canada into Vermont 18452767210551
Reposted by Selma MasriNeedhi Bhalla 💅🏽 @needhibhalla.bsky.social · 08/04/2025If a student you know received an honorable mention for the NSF GRFP, encourage them to contact their Congressional representatives! 🧪 311081
Reposted by Selma MasriEliza Bliss-Moreau @eblissmoreau.bsky.social · 07/04/2025@ucdavis.bsky.social senior admin, I sincerely hope y’all a robust response to this planned.kcra.comTrump administration revokes visas for 12 international students at UC Davis, chancellor saysThe Trump administration has revoked student visas for 12 international students at UC Davis without explanation, the university’s chancellor said on Saturday. 181
Reposted by Selma MasriDheepa Sundaram, PhD (she/her) @themodsisyphus.bsky.social · 06/04/2025They are now estimating 2.3 million across the country. Keep it going folks. #handsoff #50501protests 122103942956
Reposted by Selma MasriAllison Gill @muellershewrote.com · 03/04/2025I'm no good with patterns. Can someone help me out here? 12423551913060
Reposted by Selma MasriJeremy Berg @jeremymberg.bsky.social · 04/04/2025Temporary restraining order issued last night for the public health-related lawsuit against HHS on Tuesday) www.nytimes.com/2025/04/03/u...nytimes.comJudge Blocks H.H.S. From Terminating $11 Billion in Public Health Grants (Gift Article)A coalition of states sued over the Trump administration’s unexpected move to cut off the funds, which they said imperiled everything from childhood vaccination programs to opioid addiction treatment. 07425
Reposted by Selma MasriChrystal Starbird @drstarbird.bsky.social · 02/04/2025Finally got the notice. Very sad day for the MOSAIC program that supported some of the most amazing scientists I know, as well as some of the awesome people on my lab. 4121585
Reposted by Selma MasriSen. Cory Booker @booker.senate.gov · 02/04/2025After getting some rest, I am in awe of everyone who continues to lift their voice and speak out. This is a moment for our country, and we must make a choice about the America we want to be. 42158298010780
Selma Masri @masrilab.bsky.social · 01/04/2025Please vote and support our work @ucirvine.bsky.social!! @statnews.com 012
Reposted by Selma MasriSelma Masri @masrilab.bsky.social · 27/03/2025Please vote!! Please help us send @ucirvine.bsky.social to the finals of #STATMadness @statnews.com 011
Selma Masri @masrilab.bsky.social · 27/03/2025Please vote!! Please help us send @ucirvine.bsky.social to the finals of #STATMadness @statnews.com 011
Selma Masri @masrilab.bsky.social · 27/03/2025We need your support! @ucirvine.bsky.social has made it to the semifinals in #STATMadness @statnews.com. We need your support to send us to the finals!!! Let’s goooooo!!!! www.statnews.com/feature/stat...statnews.com2025 STAT Madness2025 bracket Welcome to STAT Madness, a bracket-style contest to find the best innovation in science and medicine. Explore groundbreaking innovations from 000
Reposted by Selma MasriJeremy Berg @jeremymberg.bsky.social · 25/03/2025A teeny bit of information officially from NIH... nexus.od.nih.gov/all/2025/03/...nexus.od.nih.govImplementation of New Initiatives and Policies Page Now AvailableWe have posted an Implementation of New Initiatives and Policies page on the public NIH Grants & Funding Website to pull together the latest information on recent and upcoming changes that impact appl... 35723
Selma Masri @masrilab.bsky.social · 24/03/2025Please vote and send us to the next round!!! @ucirvine.bsky.social 000
Reposted by Selma MasriJeremy Berg @jeremymberg.bsky.social · 23/03/2025ATTENTION If anyone has any experience with appealing terminated grants (either the process or successful strategies 😀), please DM me. THANK YOU!media.tenor.coma hello kitty sticker that says `` let me know '' .ALT: a hello kitty sticker that says `` let me know '' . 813883
Reposted by Selma MasriJameel Jaffer @jameeljaffer.bsky.social · 21/03/2025A sad day for Columbia and for our democracy. "Additionally the school believed there was considerable overlap between needed campus changes and Trump’s demands" has got to be one of the most depressing sentences ever written. www.wsj.com/us-news/educ...wsj.comExclusive | Columbia Yields to Trump in Battle Over Federal FundingColumbia’s agreement is a significant moment in the intensifying battle between Trump and elite universities. 962048506