As the parent of a child with a rare genetic disease, Celena Lozano saw the hope that reports of a breakthrough treatment bring. As a graduate student in neuroscience at UC Davis, she knows that the r...

How we focus our attention before we even see an object matters. For example, when we look for something moving in the sky, our expectation would be very different if the object is a bird flying past ...

Vision neuroscientist Marie E. Burns has been appointed the sixth director of the Center for Neuroscience (CNS), effective July 1, 2025, after serving as interim director for the past year.A professor...

Understanding exactly how psychedelics promote new connections in the brain is critical to developing targeted, non-hallucinogenic therapeutics that can treat neurodegenerative and neuropsychiatric di...

Aarrestad et al. show that, in contrast to psychedelics, the nonhallucinogenic psychoplastogen tabernanthalog promotes neuroplasticity through 5-HT2AR activation without immediately increasing extrace...

Some psychedelic compounds have been shown to be powerful promoters of growth in atrophied cortical neurons, a fact that has intrigued researchers interested in addressing one of the hallmark patholog...

UC Davis researchers describe the impact of their work and the life-altering consequences if federal funding for medical research were reduced or eliminated.

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How are memories transformed and moved over time between brain regions? We propose a simple organizing principle for how long-term memories are moved from an initial to a final site of storage, a process known as "memory consolidation." We show that successful transfer occurs when the late site of memory storage is endowed with synaptic plasticity rules that stably accumulate changes in activity occurring at the early site of memory storage. We instantiate this principle in a simple computational model that is representative of brain circuits underlying a variety of behaviors. The model suggests how a neural circuit can store new memories while preserving core features of older ones and proposes functional roles for core elements of the cerebellar circuit.

The entorhinal cortex (EC) provides the major input to the hippocampus (HPC). Numerous computational models on the EC propose that its grid cells serve as a spatial metric, supporting path integration...