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AlphaFold Unofficial

@alphafold.bsky.social
10K followers 32K following 298 posts

Unofficial account exploring the intersection of biology, molecules, science, AI and protein folding with AlphaFold.

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AlphaFold Unofficial @alphafold.bsky.social · 06/08/2026
🚨🚨 www.ft.com/content/5ab3...
ft.com
AI creates first synthetic viruses
Genomic language model has huge potential to redesign organisms such as bacteria
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AlphaFold Unofficial @alphafold.bsky.social · 06/08/2026
🚨🚨 www.forbes.com/sites/maryro...
forbes.com
AI Model Trained In DNA Invents 16 New Viruses Not Found In Nature
Scientists are worried about how smart DNA-trained artificial intelligence models could get—and that they could become a weapon in biological warfare.
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AlphaFold Unofficial @alphafold.bsky.social · 06/08/2026
🚨🚨 www.theguardian.com/science/2026...
theguardian.com
Safety fears as scientists make first viruses designed by AI
Researchers say breakthrough offers hope for new medicines but also raises urgent biosecurity questions
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GatherVerse 🦋 @gatherverse.bsky.social · 31/07/2026
Every region has women leading and solving humanity's greatest challenges. Their contributions deserve global recognition. __ Women’s AI Summit 2026 Site  gatherverse.org/women-ai-2026/ May our gather be well.
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GatherVerse 🦋 @gatherverse.bsky.social · 17/07/2026
No two women experience the world in the same way. Her life experiences tell a different human story. Every story expands AI's view of humanity. __ Women’s AI Summit 2026 Site  gatherverse.org/women-ai-2026 May our gather be well.
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GatherVerse 🦋 @gatherverse.bsky.social · 21/07/2026
Somewhere, across the world, she is discovering AI. Elsewhere, she is building and advancing it. Half a world away, she is investing in the frontier. Their stories meet here. __ Women’s AI Summit 2026 Site  gatherverse.org/women-ai-2026 May our gather be well.
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GatherVerse 🦋 @gatherverse.bsky.social · 09/07/2026
The next frontier may be defined by a woman whose voice has too often been overlooked. She belongs here. Site gatherverse.org/women-ai-2026 May our gather be well.
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GatherVerse 🦋 @gatherverse.bsky.social · 08/07/2026
In one of the most consequential chapters of human innovation, greater visibility for women leaders matters more than ever. __ Women’s AI Summit 2026 Site  gatherverse.org/women-ai-2026 May our gather be well
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GatherVerse 🦋 @gatherverse.bsky.social · 19/05/2026
She brings authorship to artificial intelligence. A leader. She brings critique, technical fluency and strategic force. Original command. The future of AI must recognize her as central to the work. Non negotiable. Women’s AI Summit 2026 Site  gatherverse.org/women-ai-2026/
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GatherVerse 🦋 @gatherverse.bsky.social · 21/05/2026
The future is too far away for women to begin to lead. Women are leading AI, across all industries. Women’s AI Summit 2026 Site  gatherverse.org/women-ai-2026/ May our gather be well.
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GatherVerse 🦋 @gatherverse.bsky.social · 10/06/2026
She arrives as author, builder, and strategist. She leads in the frontier of innovation. Women leaders belong where power is defined. __ Women’s AI Summit 2026 Site  gatherverse.org/women-ai-2026 May our gather be well
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GatherVerse 🦋 @gatherverse.bsky.social · 17/06/2026
is difficult to think of any part of life untouched by a woman's hand. As AI becomes prevalent in our world, more women are needed at the decision making table: their leadership, experiences, concerns, and contributions. __ Women’s AI Summit 2026 Site  gatherverse.org/women-ai-2026
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GatherVerse 🦋 @gatherverse.bsky.social · 30/06/2026
The horizon of artificial intelligence expands only when women guide the frontier. __ Women’s AI Summit 2026 Site  gatherverse.org/women-ai-2026 May our gather be well
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GatherVerse 🦋 @gatherverse.bsky.social · 02/07/2026
Her way forward __ Women’s AI Summit 2026 Site  gatherverse.org/women-ai-2026 May our gather be well #WomensAISummit2026 #GatherVerse #WomenInAI #AIGovernance #FutureOfTechnology #ResponsibleAI
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GatherVerse 🦋 @gatherverse.bsky.social · 06/07/2026
Human progress reaches further when women are fully represented in innovation, research, funding, governance and leadership. The impact spans generations. __ Women’s AI Summit 2026 Site gatherverse.org/women-ai-2026 May our gather be well.
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GatherVerse 🦋 @gatherverse.bsky.social · 01/07/2026
All generations of women are needed now more than ever in the most consequential and innovative time in human history. __ Women’s AI Summit 2026 Site  gatherverse.org/women-ai-2026 May our gather be well.
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GatherVerse 🦋 @gatherverse.bsky.social · 29/06/2026
Infuse intelligent machines with the perspectives and governance of women, and the future of all humanity will be protected __ Women’s AI Summit 2026 Site  gatherverse.org/women-ai-2026 May our gather be well.
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C&EN (Chemical & Engineering News) @cenmag.bsky.social · 20/06/2026
AI tools like AlphaFold have transformed the landscape of protein design in less than a decade. Meanwhile, organic chemists are still waiting for their own “AlphaFold moment” for predicting reaction recipes and routes for small-molecule synthesis. cen.acs.org/synthesis/ca... #chemsky 🧪
Chemists ran 50,688 reactions to make a huge open dataset.
The data will help train AI to predict C–N coupling conditions using cheaper catalysts.
by Brianna Barbu.
A blue-gloved hand holds a 1,536-well plate for high-throughput reaction screening.
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Carl Zimmer @carlzimmer.com · 17/06/2026
“A model of roads trained on only grid cities won’t properly predict the street plans of Rome or Boston.” An essay on the perils of AlphaFold and other kinds of AI in science cen.acs.org/pharmaceutic...
cen.acs.org
The AI Chemist: To be trustworthy, LLMs need to show their work
Good scientists reveal how they do their experiments and report their results; so should any machine-driven research
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Protein Society @proteinsociety.bsky.social · 19/06/2026
🧬 Figure Friday: Celebrating discoveries from the Protein Science community Can AI predict how proteins assemble? Ben Corry and colleagues show that AlphaFold can accurately predict the oligomeric states of many proteins, while also highlighting cases where predictions remain challenging.
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Zubnet @zubnet.bsky.social · 19/06/2026
John Jumper, the Nobel laureate behind AlphaFold, is leaving Google DeepMind after ~9 years for Anthropic. AlphaFold predicted 200M+ protein structures. Lands amid the talent war, days after Shazeer left Google for OpenAI. (Disclosure: we run on Anthropic's Claude.)
zubnet.ai
John Jumper, the Nobel laureate behind AlphaFold, is leaving Google DeepMind for Anthropic
John Jumper, who shared the 2024 Nobel Prize in Chemistry for AlphaFold, is leaving Google DeepMind after nearly nine years to join Anthropic. AlphaFold predicted 200M+ protein structures. The move lands amid the AI talent war, days after Shazeer left Google for OpenAI.
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Reconstructionist Urbanism 🇺🇸🇨🇦🇲🇽🇺🇦🇹🇼 @texasurbanist.bsky.social · 19/06/2026
www.businessinsider.com/alphafold-jo... I don't know but I consider alpha fold pretty fucking important work.
businessinsider.com
AlphaFold pioneer who won a Nobel Prize alongside Demis Hassabis leaves Google DeepMind for Anthropic
John Jumper, a key member of the team at Google DeepMind for nearly a decade, is decamping for Anthropic.
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Nathaniel Comfort @nccomfort.bsky.social · 20/06/2026
Will AlphaFold et al. figure out how the genome works? Doubtful, says @philipcball.bsky.social. I think he's absolutely right. The genome is a complex adaptive system, w/ many layers of regulation and buffering—a "sensitive organ of the cell," said Barbara McClintock—in 1983!
quantamagazine.org
Why the Human Genome’s Tangled Physicality May Confound AI | Quanta Magazine
Our genetic heritage is not a blueprint or an algorithm, as many biologists have imagined, but something else entirely.
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Dare Obasanjo @carnage4life.bsky.social · 20/06/2026
A tough week for Google’s AI efforts. Along with losing the co-lead of Gemini to OpenAI, they are also losing the Nobel Prize winning lead of the AlphaFold project at DeepMind to Anthropic. He won a Nobel Prize in Chemistry in 2024 for using AI to predict 3D protein structures.
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Cat Manning @catacalypto.bsky.social · 19/06/2026
I’m not anti-tech or investment in tech. I’m excited about solar and AlphaFold and ocean monitoring. I love science; and I know the less flashy sides of science are suffering too. I just don’t want to see the humanities, our collective history, gutted to the point where it’s too late.
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Microbiology Society @microbiologysociety.org · 08/06/2026
Isolation and characterization of broad-range Staphylococcus epidermidis sepunaviruses. Published Open Access and fee-free in Microbiology using a Publish and Read agreement: doi.org/10.1099/mic.0.001693 #Mic #PublishandRead
3D structures of the different MTases predicted using AlphaFold.
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Australian BioCommons @ausbiocommons.bsky.social · 05/06/2026
World-leading Aussie science fighting #AntimicrobialResistance! PhD student George Bouras added 17M bacterial protein predictions to the #AlphaFold database. This was made possible by a partnership between BioCommons & @pawseycentre.bsky.social to containerise #ColabFold on Setonix. Read more 🔗
biocommons.org.au
World-leading Australian science: 17M protein structures added to the AlphaFold Database to accelerate the fight against antimicrobial resistance  — Australian BioCommons
Australian researcher, George Bouras, has recently contributed an extraordinary 17 million protein predictions to the AlphaFold Protein Structure Database. This work was possible thanks to the availability of the ColabFold tool on Setonix AMD, the result of collaboration between BioCommons and the P
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EMBL-EBI Training @training.ebi.embl.org · 08/06/2026
Join us next week for our webinar, where we will demonstrate how to fetch and parse structural data using the AlphaFold Database (AFDB) APIs. Registration is free but essential to secure your place: www.ebi.ac.uk/training/eve... 🖥️🧬
Webinar at EMBL-EBI: Introduction to AlphaFold Database programmatic access. 17 June 2026, 2.30-3.30pm UK. Speaker (with headshot): Joseph Ellaway, EMBL-EBI
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Ricardo Henriques @henriqueslab.bsky.social · 05/06/2026
🔬🚀 It's out! Run 100s of imaging experiments before touching a microscope. #VLab4Mic reproduces them in silico from PDB/AlphaFold to help you image right first time. From rockstars Damián Martínez & Bruno Saraiva, inaugural preprint of @mariodelr.bsky.social new lab www.biorxiv.org/content/10.6...
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Nafnlaus 🇮🇸🇪🇺🇺🇦 @nafnlaus.bsky.social · 06/06/2026
It always gets me the lengths people go to try to argue that LLMs and image generation models "aren't really AI", and then they point to "AI" things, and they're based on the same underlying tech. AlphaFold is built on latents, diffusion, *and* Transformers.
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💙🏳️‍🌈 Kh’ymm (aka Goldie) 🏳️‍🌈💙 @thegoldfishmind.bsky.social · 07/06/2026
Before AlphaFold: Biology was like trying to understand machines without seeing their shapes. After AlphaFold: Scientists suddenly received a massive 3D blueprint library for life’s molecular machinery. This is how we can use AI for good. But w/o regulation, we risk harm to society.
deepmind.google
AlphaFold: Five Years of Impact
Explore five years of AlphaFold’s impact on biology. Learn how this Nobel Prize-winning AI is accelerating scientific discovery globally
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Roland Dunbrack 🏳️‍🌈 @rolanddunbrack.bsky.social · 07/06/2026
STOP using ipTM for #AlphaFold PPI screens. * Artificially LOW when both full-length proteins have irrelevant, non-binding IDRs/domains. * If one protein is folded & other contains irrelevant IDRs or domains, the score is too HIGH bc of d0. * Use ipSAE or LIS. www.biorxiv.org/content/10.1...
ipSAE vs ipTM for sorting true interactors from non-interactors. ipSAE is better at separating them.Post from "AF Cache: Efficient Pipeline for Running AlphaFold for High-Throughput Protein-Protein Interaction Prediction". Various scores on p53/mdm2 interaction.AlphaFOld ipTM score goes up when extra disorder is added to ONE proten. It goes way down when added to both proteins. Example of KRAS with RAF1 RBD.
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GatherVerse 🦋 @gatherverse.bsky.social · 03/06/2026
When virtual worlds can be created with a single prompt, the true measure of innovative stewardship is building with purpose, governing responsibly, and sustaining them for the benefit of humanity. Site gatherverse.org/xre2026/ May our gather be well.
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Joseph Cox @josephcox.bsky.social · 02/06/2026
New from 404 Media: we've seen internal documents that show Microsoft is explicitly planning to "make people addicted" to its new AI assistant 'Scout' which the company just announced. It is a clear goal according to the documents, with addiction being the first phase www.404media.co/microsoft-wa...
404media.co
Microsoft Wants to 'Make People Addicted' to its New AI Assistant, Internal Documents Reveal
Planning documents for "Scout" say the plan is to "make people addicted" to the tool before adding new features.
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GatherVerse 🦋 @gatherverse.bsky.social · 02/06/2026
The future of successful companies belongs to those who create opportunities for women to lead, learn, and build innovations that drive the future of AI. Join us __ Women’s AI Summit 2026 Site  gatherverse.org/women-ai-2026 May our gather be well.
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Shicheng Guo @shihcheng.bsky.social · 25/05/2026
Explore flexible macromolecule modeling with BilboMD! Access SAXS & AlphaFold-guided tools at SIBYLS & NERSC. Perfect for seamless workflow! PMID:42037134, Nucleic Acids Res 2026, @NAR_Open doi.org/10.1093/nar/gkag377 #Medsky #Pharmsky #RNA #ASHG #ESHG 🧪
doi.org
https://doi.org/10.1093/nar/gkag377
No description available
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Susie Grigson @susiegriggo.bsky.social · 26/05/2026
Enter PHLEGM! 💻🧬 We developed the Phage Homomer Level Estimate and Generation Method to infer oligomeric state using AlphaFold-Multimer and interface quality assessment. We applied it to >22,000 sequences, revealing massive structural diversity. (2/n)
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Gregor Mendel Institute of Molecular Plant Biology @gmivienna.bsky.social · 21/05/2026
Day 1 of the Mendel Early Career Symposium! 100 international researchers gathered for networking, engaging talks & posters, keynote by @emmanuellebayer.bsky.social, & workshop on ChimeraX/AlphaFold. Thanks to the sponsors for supporting expanding horizons in #PlantBiology. #Mendel_ECR_26
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Sophien Kamoun @kamounlab.bsky.social · 21/05/2026
Just published: The Hidden Handshake: How AlphaFold Solved a Decade-Long Mystery in Plant Immunity Over ten years in the making - generations of students and postdocs... Here's the structural basis of NLR activate-and-release, and, yes, we can engineer it. medium.com/p/the-hidden...
medium.com
The Hidden Handshake: How AlphaFold Solved a Decade-Long Mystery in Plant Immunity
Over ten years in the making — generations of students and postdocs, countless false starts, and others were chasing this too. Here’s the…
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Richard Sever @richardsever.bsky.social · 27/05/2026
Doudna: “we don’t have the data…biological data are limiting…we need AI approaches that acknowledge this” Jennifer gives the example of Alphafold dependence on PDB at #cshlsymposium2026 noting that other areas like protein-NA complexes will need more data for AI to help.
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GAMA Miguel Angel @miangoar.bsky.social · 20/05/2026
Today, the AlphaFold2 paper reached the milestone of 50k citations according to Google Scholar! And AlphaFold3 will likely reach 15k citations tomorrow. Congratulations to the entire AlphaFold team, as well as to all the scientists who helped democratize protein structure prediction 🥳
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Alexis Verger 🧬🧫🧪 @alexis-verger.cpesr.fr · 20/05/2026
When AlphaFold was released, there was a lot of talk that it marked the end of structural biology. That is far from the case. We will, I’m sure, hear similar comments with the emergence of AI co-scientist agents. AI is just a tool but It will never replace a scientist’s intuition & experience.
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Mauricio Contreras @mpcontreras.bsky.social · 20/05/2026
Check out our latest work! AlphaFold 3 revealed a transient immune receptor complex that eluded biochemical studies for almost a decade 🤯 We describe a conserved structural logic underlying sensor–helper communication in an NLR immune receptor network 🧵👇
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Mauricio Contreras @mpcontreras.bsky.social · 20/05/2026
And then @googledeepmind.zpravobot.news.ap.brid.gy AlphaFold 3 came to the rescue! It predicted a high-confidence complex between Rx and NRC2, a sensor-helper pair in the NRC network. We consistently got confident predicitons across 10 independent models (ipTM = 0.76)!.
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Protein Data Bank in Europe (PDBe) @pdbeurope.bsky.social · 20/05/2026
1/6 🧪 Big news for structural biology and AI: PDBe is now AI-native. We’ve built MCP Servers that connect the Protein Data Bank in Europe and the Alphafold Protein Structure Database directly to Claude and other MCP-compatible AI systems. Here’s what that unlocks 👇
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MeidasTouch @meidastouch.com · 21/05/2026
MeidasTouch: What do you make of this $1.776 billion fund— Gavin Newsom: It’s a criminal enterprise. It’s not just corruption, it’s not just graft, it’s a full-on criminal enterprise and it needs to be shut down.
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Governor Gavin Newsom @governor.ca.gov · 19/05/2026
The system is broken. It needs to be reimagined.
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Governor Gavin Newsom @governor.ca.gov · 19/05/2026
The Right needs new talking points and a check on their California Derangement Syndrome. California is the top-performing economy in the US. We dominate in EVERY category — from manufacturing to venture capital, engineering, and research. We are writing the rules of the future.
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GatherVerse 🦋 @gatherverse.bsky.social · 20/05/2026
She rises where artificial intelligence meets gravity, wonder, and responsibility. Her leadership gives technology a finer sense of proportion. The machine age needs women who can keep power aligned with life. __ Women’s AI Summit 2026 Site  gatherverse.org/women-ai-2026/ May our gather be well
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AlphaFold Unofficial @alphafold.bsky.social · 20/05/2026
Just announced: ai.google/gemini-for-s...
ai.google
Gemini for Science
Powering scientific discovery with AI
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