Epithelial tissues serve as critical physical barriers that protect organs, making their efficient repair essential upon damage. To achieve this, tissues must quickly react, forcing cells to rearrange...

Four scientists shared their experience on the benefits of journal-agnostic peer review.

Highlighted Article: YAP activation in notochord progenitors of vgll4b mutant zebrafish leads to enhanced progenitor addition to the notochord, compromising the ability of notochord cells to undergo v...

Global shift towards clean electricity could trigger ‘cascade’ of progress, helping reduce air pollution, cut waste and revive oceans

The long read: Scientists are battling over whether supposedly simple organisms should be considered ‘intelligent’. The outcome could reshape our understanding of the natural world – and our own place...

This EMBO Workshop on Forces Across Scales will provide an integrative perspective on mechanobiology, a rapidly advancing field that examines how mechanical forces shape biological systems across mol…

Autosomal recessive polycystic kidney disease (ARPKD) is caused by impaired function of fibrocystin/polyductin (FPC) in collecting duct epithelia resulting in cyst formation. We hypothesized that the ...

Cavanaugh et al. show that embryos from aged mice have increased contractility and tissue viscosity on embryonic day 4.5, which leads to poor spreading and attachment. Similar age-associated mechanica...

Cell biologists have long known that mechanical forces, such as tension and compression, influence tissue differentiation. Now, advanced methods are letting them observe and manipulate these forces in...

Songwriter of I Will Always Love You, Jolene and 9 to 5 also invested millions in child literacy, Covid-19 vaccine development and other causes

Here the authors show that intestinal stem cells reorganize their Golgi apparatus to improve the delivery of receptors that receive signals from nearby support cells. This adaptation promotes efficien...

“I considered whether I should email Abcam and ask them to change the name of the ab51243 antibody on their website to reduce confusion, but […] I will instead continue to watch the car…

🎨 Toolkit for generating publication-quality plots for Cell, Nature and Science journals - faridrashidi/cnsplots

Robust tissue growth control requires long-range communication between the rate of progenitor addition and tissue expansion. However, the regulatory mechanisms that couple these processes are unknown....

Cell monolayers are active, orientationally ordered materials whose mechanics can depart from near-equilibrium behavior. Existing continuum theories often inherit assumptions from equilibrium liquid-c...

The Cambridge academic has rightly now resigned. But that won’t end the targeting of senior black figures or the lazy way institutions promote faux equality, says Guardian columnist Jason Okundaye

Basement membranes are scaffolds of proteins, like collagen, that give organs shape. During development, basement membranes must adapt to the growing organ. We infer how fast the basement membrane adapts by measuring collagen turnover. We find that perlecan, another basement membrane protein, regulates collagen turnover to control organ shape.