Sign in

Elisha Krieg

@elishakrieg.bsky.social
89 followers 70 following 48 posts

Group leader in DNA Nanotech at Leibniz IPF and TU Dresden. Group website: krieg-lab.de Startup: dynamicmatrices.eu

PostsRepliesMedia
Reposted by Elisha Krieg
Elisha Krieg @elishakrieg.bsky.social · 06/08/2026
How can we record the mechanical activity of cells in three dimensions? Our DNA force-history probes convert transient piconewton forces into persistent fluorescent signals, revealing spheroid activity, cellular protrusions, and migration tracks in a 3D matrix. www.biorxiv.org/content/10.6...
1167
Reposted by Elisha Krieg
André Nadler @nadlerlab.bsky.social · 18/08/2026
A good teaser for our recent story on lipid-protein interactions by @cookkate.bsky.social with really kind quotes by @jeremybaskin.bsky.social (Thanks!!)
03913
Elisha Krieg @elishakrieg.bsky.social · 06/08/2026
How can we record the mechanical activity of cells in three dimensions? Our DNA force-history probes convert transient piconewton forces into persistent fluorescent signals, revealing spheroid activity, cellular protrusions, and migration tracks in a 3D matrix. www.biorxiv.org/content/10.6...
1167
Elisha Krieg @elishakrieg.bsky.social · 04/08/2026
Excited that the first #DyNAtrix 🧬 Pilot kits from @dynamicmatrices.bsky.social are now available at PELO Biotech GmbH General info: dynamicmatrices.eu/dynatrix/ Try the Ready-to-Use kit: www.pelobiotech.com/en/contact/?... Minimal Discovery kit: www.pelobiotech.com/en/contact/?... #CellCulture
032
Elisha Krieg @elishakrieg.bsky.social · 17/06/2026
Thanks to Advanced Materials for selecting our article on "Olympic" gels for a cover! 🔗🔗🔗🔗🔗🔗🔗🔗🔗 advanced.onlinelibrary.wiley.com/doi/abs/10.1... #MaterialsScience #Biotechnology #Nanotechnology
This cover illustrates the molecular structure of an “Olympic gel” composed of mechanically interlocked plasmids. The ring-shaped DNA molecules can reversibly open and close via diversified lock-and-key domains, enabling controlled formation of mechanical bonds. The study shows that combinatorial synthetic biology can yield compositionally complex soft materials with exotic topological architectures and unique physical characteristics. More information: DOI:10.1002/adma.202520549
173
Elisha Krieg @elishakrieg.bsky.social · 29/04/2026
Looking forward to speak at the upcoming Leibniz HealthTech Lecture: "Dynamic Matrices – a material platform for precisely controlled cell culture and ultra-selective biomolecule isolation" 🌍 online 📅 May 4th | 13:30-15:00 (CEST) 🔴 Register here: www.leibniz-healthtech.de/en/news/even...
leibniz-healthtech.de
Leibniz HealthTech Lecture: Dynamic Matrices - a material platform for precisely controlled cell culture and ultra-selective biomolecule isolation
100
Reposted by Elisha Krieg
Azra Atabay @azratabye.bsky.social · 06/03/2026
Working on this collaborative project in the Krieg lab has been a real pleasure. It began as a side ninja project with almost no budget but has grown and expanded so much. Really proud of what we have accomplished🥺 please check it out: advanced.onlinelibrary.wiley.com/doi/10.1002/...
advanced.onlinelibrary.wiley.com
Assembling a True “Olympic Gel” From over 16 000 Combinatorial DNA Rings
Olympic gels are an elusive class of soft matter, consisting of molecular networks held together purely by mechanically interlocked rings. Their topological structure promises unique properties and f...
032
Elisha Krieg @elishakrieg.bsky.social · 06/03/2026
🔴Finally out TODAY in Advanced Materials: “Assembling a True Olympic Gel From over 16 000 Combinatorial #DNA Rings” #MaterialsScience #Nanotechnology Explainer thread below 👇👇👇
111
Elisha Krieg @elishakrieg.bsky.social · 19/12/2025
Just out in @angewandtechemie.bsky.social! #LASSO a new method for ultra-selective isolation of biomolecules (DNA, RNA, or protein). This method uses a unique polymer phase separation mechanism to gently capture and pull down specific target sequences.
132
Reposted by Elisha Krieg
Tanja Weil @weilgroup.bsky.social · 16/12/2025
More great news for the holidays🎄 Our new review on "Functionalizing Nucleic Acids: Synthesis and Purification Strategies for Bioconjugates as Biomaterials" is out: onlinelibrary.wiley.com/doi/10.1002/... Many thanks to Nico Alleva, Jian Zhang and Torsten John!
onlinelibrary.wiley.com
Functionalizing Nucleic Acids: Synthesis and Purification Strategies for Bioconjugates as Biomaterials
Nucleic acid-ligand conjugates combine the distinct properties of macromolecular ligands with the versatility of DNA/RNA nanotechnology. In biomaterial and nanomedicine applications, highly purified ...
031
Elisha Krieg @elishakrieg.bsky.social · 03/12/2025
Thanks to Advanced Functional Materials for highlighting our work on their back cover!
223
Elisha Krieg @elishakrieg.bsky.social · 15/11/2025
Big congrats to Dr. Krishna Gupta for winning the best poster prize at Oxford Global’s NextGen Omics conference in London, where he presented our work on #LASSO pulldown polymers. 💪 LASSO is a new general-purpose method for fast and ultra-selective biomolecule purification.
112
Reposted by Elisha Krieg
Andreas Walther @waltherlab.bsky.social · 23/10/2025
Fresh in @natchemeng.nature.com Growing artificial cytoskeleton in the viscoelastic confinement of DNA Artificial Cells. Brilliant work bey Weixiang! #Syntheticcell #systemschemistry www.nature.com/articles/s44...
nature.com
Growing functional artificial cytoskeletons in the viscoelastic confinement of DNA synthetic cells - Nature Chemical Engineering
Engineering structurally and functionally complex synthetic cells remains a key challenge. Here DNA condensate synthetic cells combine phase separation and DNA nanostructures to reveal how switchable ...
0228
Reposted by Elisha Krieg
Andreas Walther @waltherlab.bsky.social · 23/10/2025
Congratulations to Soumya and Charu for making the first ATP-fueled homeostatic cytokine delivery system for communication between artificial and living cells. Now in Angewandte Chemie @angewandtechemie.bsky.social #syntheticcell #noneqsys #DNAnanoscience onlinelibrary.wiley.com/doi/10.1002/...
onlinelibrary.wiley.com
ATP‐Powered Signaling Between Artificial and Living Cells
We introduce an ATP-powered artificial cell platform capable of selectively and transiently releasing DNA signals to facilitate communication between artificial and living cells. By engineering these...
072
Elisha Krieg @elishakrieg.bsky.social · 23/10/2025
Multiplexed detection of viral pathogens on an AUTONOMOUSLY LOADING chip for point-of-care #diagnostics. Congrats to first authors Beatrise Berzina and Krishna Gupta and the entire EKFZ-funded *VirChip* team!
273
Reposted by Elisha Krieg
Max Planck Institute of Molecular Cell Biology and Genetics @mpi-cbg.de · 30/09/2025
Schering Young Investigator Award 2025 by the Schering Stiftung for Agnes Toth-Petroczy @tothpetroczylab.bsky.social @mpi-cbg.de @csbdresden.bsky.social. She receives the award for her work on the evolution, diversity, and function of proteins. Congratulations! 🎉 www.mpi-cbg.de/news-outreac...
mpi-cbg.de
New Perspectives on the Hidden World of Proteins
 Schering Young Investigator Award 2025 goes to Agnes Toth-Petroczy
1315
Reposted by Elisha Krieg
Prof Ben Britton @bmatb.expmicromech.com · 18/09/2025
This is doing the rounds in my messages with colleagues, and is a very real threat to the field of microscopy 😬. Given one (published) microscope image probably costs between $100 and $10,000 (or more) to make - the lure of "oh I will just ChatGPT it" is very much there.
1176
Elisha Krieg @elishakrieg.bsky.social · 15/09/2025
AI can now generate fake microscopy images that are nearly impossible to detect. A serious threat to scientific integrity—and we’re not prepared for it. Commentary in @natnano.nature.com #nanotechnology
616375
Elisha Krieg @elishakrieg.bsky.social · 11/09/2025
Exciting application of our programmable #CellCulture matrix #DyNAtrix. By creating a mechanically reconfigurable microenvironment, we can now invert & guide epithelial cell polarity in real time. #DNAnanotech 1/ 🧵
1124