On a vu à plusieurs reprises sur ce blog que les organismes vivants produisent des protéines adaptées à leur mode de vie. C’est ainsi par exemple que les récepteurs gustatifs d’un anima…

Abstract. Ribonucleic acid (RNA) molecules fold into complex, highly dynamic three-dimensional conformational structures that govern their biological activ

The integration of coarse-grained (CG) approaches into docking workflows offers a powerful strategy for modeling large biomolecular assemblies with reduced computational costs. We present here the im...

Appelé également ourson d’eau, le tardigrade est un petit bibendum miniature (d’environ 0,5 mm), que l’on peut trouver dans les mousses et lichens dont il se nourrit. Il a été déc…

Abstract. Increasing knowledge of the wide range of biological functions of ribonucleic acids (RNAs) has made them a critical target in drug development. A

Microtubules are key components of the eukaryotic cytoskeleton involved in vital functions in virtually every cell. Among the emerging molecular mechanisms to adapt microtubules to their diverse funct...

Alt: ALF It's time

Rational design of covalent protein-labeling reagents in complex biological environments requires a molecular-level understanding of how the protein microenvironment governs chemical reactivity; yet, ...