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David De Sancho

@daviddesancho.bsky.social
648 followers 778 following 148 posts

Protein Folder, father of two, married to @mariacaffarel.bsky.social at UPV-EHU and DIPC sites.google.com/view/biokt

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Reposted by David De Sancho
BioExcel CoE @bioexcelcoe.bsky.social · 25/09/2026
📢 Join us for our next webinar where Carter J. Wilson from @compbiophys.bsky.social will present our latest work on quantifying covalent modifications in #proteins 🗓️ 13 October at 15:00 CET ✍️ bioexcel.eu/zu7m #ComputerSimulation #freeenergy #GROMACS #PMX
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Reposted by David De Sancho
sbesp.bsky.social @sbesp.bsky.social · 22/09/2026
Check out the August 2026 #SBEpaperofthemonth López-Perrote A et al. "CONCR lncRNA organizes a 3'-end structural domain that engages DDX11 for DNA replication and sister chromatid cohesion" Mol Cell. 2026 doi.org/10.1016/j.mo... @maitehuartelab.bsky.social
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David De Sancho @daviddesancho.bsky.social · 01/09/2026
Check out our first contribution to the #nanoneuro project🧠, led by super-star postdoc Dulce Guzmán Ocampo "Molecular basis of AMPA receptor labeling by ligand-directed acyl imidazole chemistry in living neurons" biorxiv.org/content/10.6... @dipcehu.bsky.social
biorxiv.org
Molecular basis of AMPA receptor labeling by ligand-directed acyl imidazole chemistry in living neurons
Rational design of covalent protein-labeling reagents in complex biological environments requires a molecular-level understanding of how the protein microenvironment governs chemical reactivity; yet, ...
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Reposted by David De Sancho
RCSB Protein Data Bank @rcsbpdb.bsky.social · 01/09/2026
From 2000: Ribosomal Subunits Atomic structures of the ribosomal subunits reveal a central role for RNA in protein synthesis
pdb101.rcsb.org
PDB101: Molecule of the Month: Ribosomal Subunits
Atomic structures of the ribosomal subunits reveal a central role for RNA in protein synthesis
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Reposted by David De Sancho
sbesp.bsky.social @sbesp.bsky.social · 28/08/2026
Check out the July 2026 #SBEpaperofthemonth Sen-Martín et al, "Mavacamten shows broad benefit in human and mouse models of MYBPC3-related hypertrophic cardiomyopathy" @natcardiovascres.nature.com 2026 Jul;5(7):638-657. doi: 10.1038/s44161-026-00833-3
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Reposted by David De Sancho
C&EN (Chemical & Engineering News) @cenmag.bsky.social · 08/06/2026
Cyclic peptides, such as this one conceived by Yu-Shan Lin’s group at Tufts University, are increasingly being explored for their therapeutic potential. #chemsky 🧪
cen.acs.org
Cyclic peptides are having a moment
In this Eye on Patents column, we explore the pharmaceutical industry’s embrace of these circular molecules
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David De Sancho @daviddesancho.bsky.social · 03/06/2026
Happening tomorrow! If in San Sebastián, do not miss!
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Reposted by David De Sancho
EMBL Events @events.embl.org · 22/05/2026
Hard to believe that 'Cellular mechanisms driven by phase separation' is over! With everyone already on their way back, we can't stop thinking about what a brilliant time we've had over the past 4 days. Safe travels and stay tuned for more info on the poster prize winners! #EESPhaseSeparation 🧪
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EMBL Events @events.embl.org · 20/05/2026
Day 2 of 'Cellular mechanisms driven by phase separation' going well so far, with the first poster session behind us! 📊🔍 Looking forward to many interesting talks still ahead of us as well as to more time to socialise this evening 💬 #EESPhaseSeparation @embo.org @embl.org
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BioExcel CoE @bioexcelcoe.bsky.social · 22/04/2026
Atomistic #moleculardynamics simulations of short #peptides can lead to better understanding more complex molecular systems. Join us to hear more from @daviddesancho.bsky.social 🗓️ 12 May 2026, 15:00 CET ✍️ bioexcel.eu/dx7m #ComputerSimulation #biophysics #proteins
bioexcel.eu
Webinar: Driving forces in biomolecular condensates from atomistic simulations of model peptides (2026-05-12)
Date: 12 May 2026 Time: 15:00 CET Registration Abstract Short peptides have been instrumental as models for more complex systems. Studying short peptides, we have gained understanding of fundamental ...
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Reposted by David De Sancho
DIPC @dipcehu.bsky.social · 15/04/2026
Tomorrow #DIPCcolloquia 👇 📌 Density Functional Theory: Why It Works, Why It Matters, and What Comes Next  👨‍🔬 Kieron Burke, School of Physical Sciences, @ucirvine.bsky.social  🗓️ April 16, 16h 🏫 DIPC Josebe Olarra Seminar Room
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Rosana Collepardo @rcollepardo.bsky.social · 15/04/2026
Check out our latest work in collaboration with @kazu-maeshima.bsky.social and @masaashimazoe.bsky.social We show that H1 is a dynamic, multivalent “liquid-like” glue of chromatin in cells: it bridges multiple nucleosomes & exchanges partners frequently to enable both compaction and flexibility
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BioExcel CoE @bioexcelcoe.bsky.social · 19/01/2026
⭐️ Registration and Abstract submission is open for the "3rd BioExcel Conference on Advances in Biomolecular Simulations" 🗓️ 27 - 30 September 2026 📍 Brno, Czechia ℹ️ More info: bioexcel.eu/hzr0 #molecularsimulation #moleculardynamics #AI #compchem #drugdesign #molecule #computing #conference
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Protein Society @proteinsociety.bsky.social · 16/03/2026
⏳ 1 day left! The deadline for PS40 Open Talks & Travel Awards is March 17. ✈️ 100+ travel awards available 🔬 Opportunity to present an Open Talk Join us in Boston (July 19–22) for The Protein Society’s 40th Anniversary Symposium. Submit here: www.proteinsociety.org/annual-sympo... #PS40
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BioExcel CoE @bioexcelcoe.bsky.social · 16/03/2026
Don't forget to register! Our #webinar "Peeking into the black box of GROMACS performance" is happening tomorrow 🗓️ 17 March 2026, 15:00 CET ✍️ bioexcel.eu/oryy #webinar #moleculardynamics @gromacs.bsky.social
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BioExcel CoE @bioexcelcoe.bsky.social · 29/01/2026
Interested in best practices for creating and maintaining reproducible workflows for biomolecular simulations? Join us for our #webinar 🗓️ 17 February 2026, 15:00 CET ✍️ bioexcel.eu/7c2s #molecularsimulations #workflows #FAIR #SoftwareEngineering @coderefinery.org
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Kresten Lindorff-Larsen @lindorfflarsen.bsky.social · 18/12/2025
Are you interested in integrative structural biology, but feel a bit lost? Don't worry, we have you covered with our FEBS Advanced Course, Lost in Integration Vol. 2 — probing biomolecules with AI and experiments probingbiomolecules2026.febsevents.org network.febs.org/posts/integr...
Poster for the conference
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Daniel Reta @danireta.bsky.social · 16/12/2025
📣 we are hiring! We are looking for candidates for a fully funded PhD position at EHU to study organic radicals and charge-to-spin conversion mechanisms using computational chemistry methods @ec.europa.eu 👩‍🔬🧑‍🔬 📅 Deadline: April 17 👇 Details below, please RT www.danielreta.com/phd-computat...
danielreta.com
PhD in Theoretical Chemistry and Computational Modelling — Daniel Reta Research Group
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Kimika Teorikoa Lab @theochemehu.bsky.social · 01/12/2025
Fresh news! 📷 Registration & Abstract Submission for #DFT2026 Now Open! Register before 15 March 2026 to secure the early bird fee! Abstract submission is open until 31 May 2026. Find all details here: dft2026.com
dft2026.com
DFT 2026
21st International Conference on Density Functional Theory and its Applications
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MDDB @mddbeu.bsky.social · 26/11/2025
Excited to share a fantastic set of sessions coming up at the MDDB Conference: Day 1: Large-scale MD simulations Day 2: MD kinetics and free energy / Industrial applications of MD Day 3: Innovative applications of MD to biological systems Explore more and register at ➡️ mddbr.eu/conference/ #MDDB
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Cole Group @colegroupncl.bsky.social · 19/11/2025
📢 We have a fully funded PhD studentship available for Oct 2026 start on "Training force fields for computer-aided drug design with machine learning", in collaboration with Ioan Magdau and SandboxAQ. Full details and how to apply: www.ncl.ac.uk/postgraduate... Closing date: 18 Jan 2026 #compchem
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Sociedad Española de Bioquímica y Biología Molecular (SEBBM) @sebbm.bsky.social · 07/11/2025
Queridos y queridas colegas, es un verdadero honor invitaros al 48º Congreso Internacional de la Sociedad Española de Bioquímica y Biología Molecular (SEBBM), que celebraremos en la ciudad de Tarragona del 7 al 10 de septiembre de 2026. ¡Reservad vuestras fechas!
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Agencia Estatal de Investigación @ageinves.bsky.social · 30/10/2025
¡No te pierdas los próximos #webinariosAEI! ➡️ Ramón y Cajal 2025 (#RYC2025): 12 noviembre, 12:00h → lnkd.in/dgzXYSQF ➡️ #PID2025: 18 noviembre, 10:30h → lnkd.in/dnX4JfSN ➡️ #CPP2025: 11 diciembre, 12:00h → lnkd.in/dW4ZYnqS www.aei.gob.es/noticias/age...
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Iker Badiola @ikerbadiola.bsky.social · 23/10/2025
Aurkines, an alternative to traditional chemotherapy for cholangiocarcinoma treatment. mappingignorance.org/2025/10/16/a...
mappingignorance.org
Aurkines could spark a new era in fighting resistant cancers
Aurkines cause rampant DNA double-strand breaks, spark apoptosis, and curb growth in both naïve and resistant tumours in mice
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Reposted by David De Sancho
MRC Laboratory of Molecular Biology @mrclmb.ac.uk · 08/10/2025
John Gurdon, former Group Leader and Head of @cellbiol-mrclmb.bsky.social has died. Despite calling himself a "total non-intellectual” his work to reprogramme somatic cells to pluripotent stem cells transformed the field of developmental biology. More: www2.mrc-lmb.cam.ac.uk/john-gurdon-... #LMBNews
Black and white portrait of John Gurdon, 1971
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C&EN (Chemical & Engineering News) @cenmag.bsky.social · 08/10/2025
The 2025 #NobelPrize in Chemistry has been awarded to Susumu Kitagawa, Richard Robson and Omar M. Yaghi “for the development of metal–organic frameworks.” Stay tuned for the full story to come! cen.acs.org/people/nobel... #ChemNobel #Chem #Chemistry #chemsky 🧪
cen.acs.org
The 2025 chemistry Nobel goes to MOFs
Susumu Kitagawa, Richard Robson and Omar M. Yaghi win the prize for developing metal–organic frameworks
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Kimika Teorikoa Lab @theochemehu.bsky.social · 03/10/2025
🧑‍🎓We have a new PhD!!!! 🥳 Congrats to the great Antonio Cebreiro, who today defended his PhD, supervised by David Casanova @dipcehu.bsky.social
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David De Sancho @daviddesancho.bsky.social · 03/10/2025
Check out our latest, where we investigate the molecular origin of differences between Lys and Arg and their roles in biomolecular #condensates @dipcehu.bsky.social www.biorxiv.org/content/10.1...
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David De Sancho @daviddesancho.bsky.social · 01/10/2025
May she rest in peace
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Sarah Shammas @sarahshammas.bsky.social · 01/10/2025
Why are transcription factors disordered? Come join us in Oxford as a postdoc and we'll find out together! Help publish 3 mature projects, AND develop cool new single molecule fluorescence binding assays! biophysics transcription protein:DNA interactions my.corehr.com/pls/uoxrecru...
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David De Sancho @daviddesancho.bsky.social · 29/09/2025
Last week, we were lucky to have Jorge Reñé Espinosa from @ucm.es visiting us at UPV-EHU and @dipcehu.bsky.social If you missed his talk, here is the recording for your delight 👇 www.youtube.com/watch?v=ibsJ...
youtube.com
Multiscale modelling of liquid-liquid and liquid-solid transitions in biomolecular condensates
YouTube video by Donostia International Physics Center
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David De Sancho @daviddesancho.bsky.social · 26/09/2025
Happening in ~1 hour 👇
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Alberti Lab @ TU Dresden @albertilab-tud.bsky.social · 23/09/2025
++++ We are hiring ++++ The DFG-funded Research Training Group RTG 3120 – Biomolecular Condensates: From Physics to biological Functions” in Dresden is currently recruiting PhD-candidates. More Info here: dresdencondensates.org/join-us/ Please apply until October 31,2025
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BioExcel CoE @bioexcelcoe.bsky.social · 23/09/2025
Last chance to register ❗️ Our special edition webinar featuring talks on #topoisomerase inhibition, transmembrane #signalling and #membrane multilamellarity is this afternoon at 15:00 CEST Register here ➡️bioexcel.eu/ion8
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David De Sancho @daviddesancho.bsky.social · 22/09/2025
Condensate aficionados, this week, do not miss Jorge Reñe Espinosa's talk at @dipcehu.bsky.social Friday 26 September: 12:00 PM CET Zoom: dipc-org.zoom.us/j/97796482927 YouTube: youtube.com/live/ibsJcLv...
dipc-org.zoom.us
Join our Cloud HD Video Meeting
Zoom is the leader in modern enterprise cloud communications.
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Kimika Teorikoa Lab @theochemehu.bsky.social · 22/09/2025
Eduard Matito and Mario Piris from our lab presenting their recent work at QVEST2025 at Schloss Ringberg @dipcehu.bsky.social @ehu.eus
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Peter Kenny @pwk2024.bsky.social · 22/09/2025
#PostDoc opportunity in molecular #biophysics and structural biology at University of Cambridge (UK) ref: PH47220 | duration: funding to 31-Dec-2028 | closing: 09-Oct-2025 #StructBiol #MolBiol #PostDocJobs #chemsky 🧪 www.jobs.cam.ac.uk/job/52745/
jobs.cam.ac.uk
Research Associate - Stott Group - Job Opportunities - University of Cambridge
Research Associate - Stott Group in the Department of Biochemistry at the University of Cambridge.
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Ignacio Arganda-Carreras @iarganda.eurosky.social · 20/09/2025
¿Alguien en Bilbao hoy (sábado 20 de septiembre)? No perderse la charla de la maravillosa @elirezabal.bsky.social 😍 (@theochemehu.bsky.social, @dipcehu.bsky.social) en @naukas.bsky.social #NAUKAS2025 ⏰11:30 a 11:40 – 💫Elixabete Rezabal💫 – ¿Hueles vibraciones? 👃📳 naukas.com/2025/09/12/p...
naukas.com
Programa definitivo de Naukas Bilbao 15º Aniversario - Naukas
Programa definitivo Naukas Bilbao 15 Aniversario (19 al 21 septiembre 2025)
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David De Sancho @daviddesancho.bsky.social · 19/09/2025
It never ends
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David De Sancho @daviddesancho.bsky.social · 17/09/2025
Out in its final form pubs.acs.org/doi/10.1021/...
pubs.acs.org
Resolving Molecular Interactions in Protein Folding Trajectories with NCIPLOT
Noncovalent interactions (NCIs) are fundamental to the structure, stability, and function of proteins. These interactions form complex networks that control how different protein regions relate to eac...
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David De Sancho @daviddesancho.bsky.social · 15/09/2025
Still on time to apply
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Samrat Mukhopadhyay @samratmukhopadhyay.bsky.social · 12/09/2025
What a terrific recognition of our research field! Dirk Görlich (Max Planck Institute Göttingen) and Steven McKnight (UT Southwestern) received the Lasker Award for their work on low-complexity domains and their phase separation. Read the perspective in PNAS: www.pnas.org/doi/epdf/10....
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Albert and Mary Lasker Foundation @laskerfdn.bsky.social · 11/09/2025
The discoveries of D. Görlich & S. McKnight exposed the structures and functions of low-complexity domains within protein sequences, revealing new principles of intracellular transport and organization. 🧪 #LaskerAward #Lasker2025 #phaseseparation @mpi-nat.bsky.social www.youtube.com/watch?v=962P...
youtube.com
Low-complexity domains: structures & functions
YouTube video by Albert and Mary Lasker Foundation
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David De Sancho @daviddesancho.bsky.social · 11/09/2025
This preprint by @elisedd.bsky.social and @sacquin-mo.bsky.social seems consequential for people performing MD studies of phosphorylated IDPs #MustRead
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David De Sancho @daviddesancho.bsky.social · 09/09/2025
📣 @xabierjota.bsky.social and I are looking for candidates for a fully funded PhD position at UPV / EHU to study intrinsically disordered proteins using molecular simulations and computational chemistry calculations 👩‍🔬🧑‍🔬 📅 Deadline: October 1st 👇 Details below, please RT
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CompBioPhys @compbiophys.bsky.social · 02/09/2025
📢 We are hiring #PhD students and #Postdocs at the @mpi-nat.bsky.social in in the Department of Theoretical and Computational #Biophysics in Göttingen 🇩🇪! 🔗 check our current job adverts at www.mpinat.mpg.de/grubmueller and find your project. Submit your #application today! #job
mpinat.mpg.de
Helmut Grubmüller
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David De Sancho @daviddesancho.bsky.social · 24/08/2025
"standardized test scores help lower-income groups get into the best schools"
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David De Sancho @daviddesancho.bsky.social · 11/08/2025
#MustRead paper for condensate fans (it's all in the contact map) Predicting heteropolymer phase separation using two-chain contact maps pubs.aip.org/aip/jcp/arti...
pubs.aip.org
Predicting heteropolymer phase separation using two-chain contact maps
Phase separation in polymer solutions often correlates with single-chain and two-chain properties, such as the single-chain radius of gyration, Rg, and the pair
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Derek Lowe @dereklowe.bsky.social · 06/08/2025
This is a crime. I can’t put it any other way.
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Ana Beloqui Elizazu @polyzymeslab.bsky.social · 04/08/2025
We are hiring!! 📢 📢 Looking for a motivated (bio)chemist/biophysicist/biotechnologist to work in an exciting project funded by Ramon Areces Foundation together with the group of Matías Picchio at POLYMAT.
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