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Gabi Heller

@g-heller.bsky.social
231 followers 321 following 7 posts

Drugging intrinsically disordered proteins Co-Founder/CEO/CSO, Bind Research (bindresearch.org, @bindresearch.org) PI, eXtreme Dynamics & Therapeutics Lab, UCL (she/her)

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Reposted by Gabi Heller
Gogs Karunanithy @gogs-k.bsky.social · 22/09/2026
Assigning the backbone of a disordered protein is often weeks of work before the biology can even start. I’m sure I’m not alone in having spent long days staring at a stack of spectra, wishing for a just a little more resolution. We built SpinForecast to help!
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Gabi Heller @g-heller.bsky.social · 22/09/2026
Our mission is to make intrinsically disordered proteins (IDPs) druggable for everyone. Our first tool, SpinForecast, developed by @bindresearch.org with @ucl.ac.uk, takes a step towards that goal by dramatically speeding up #NMR assignments for IDPs. 🍝🧲🖥️
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Reposted by Gabi Heller
Bind Research @bindresearch.org · 18/03/2026
Accompanying Current Opinion in Structural Biology: doi.org/10.1016/j.sb...
doi.org
Redirecting
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Reposted by Gabi Heller
Bind Research @bindresearch.org · 18/03/2026
White paper: doi.org/10.5281/zeno...
doi.org
Making disordered proteins druggable
Intrinsically disordered proteins (IDPs) represent one of the largest remaining frontiers in molecular medicine. More than 30% of residues in the human proteome are intrinsically disordered, and many ...
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Reposted by Gabi Heller
Bind Research @bindresearch.org · 18/03/2026
Disordered proteins play key roles in disease but remain largely out of reach for drug discovery. The prevailing assumption is that they are undruggable. At Bind, we ask what it would take to make them druggable at scale. See our white paper and accompanying COSB below.
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Gabi Heller @g-heller.bsky.social · 24/03/2025
We’re looking for fellow nerds to help us make disordered proteins druggable. Love #IDPs, #MD, #NMR, #AI, #DrugDiscovery, or #MassSpec? Let’s talk. @bindresearch.org is hiring across the board: bindresearch.org/careers/ #compchem #compbio #NMRChat #TeamMassSpec #chemjobs @chemjobber.bsky.social
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Reposted by Gabi Heller
Gogs Karunanithy @gogs-k.bsky.social · 11/02/2025
Delighted to announce @tlhr.bsky.social, @g-heller.bsky.social and I are building the UK’s first FRO @bindresearch.org with the goal of making disordered proteins druggable. Interested in doing breakthrough open science in an innovative organisation in Central London? We’d love to hear from you!
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Reposted by Gabi Heller
Thomas Löhr @tlhr.bsky.social · 11/02/2025
Incredibly excited to be starting @bindresearch.org with @gogs-k.bsky.social and @g-heller.bsky.social! We are a not-for-profit research startup based in London, creating tools and datasets to make disordered proteins druggable.
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Gabi Heller @g-heller.bsky.social · 11/02/2025
Today @gogs-k.bsky.social, @tlhr.bsky.social, and I are launching @bindresearch.org, a UK-based not-for-profit research startup to deliver publicly–available tools and datasets to make intrinsically disordered proteins druggable. 🍝 💊🧲 💻 🦠
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