PhD Project - EASTBIO - Investigating how neural signalling regulates adaptive immune responses at University of Edinburgh, listed on FindAPhD.com

When these energy-giving organelles thrive, so do we

A new study shows that people Zepbound lost about 50% more weight than those using Wegovy. It was the first head-to-head trial of the blockbuster weight-loss medications.

Human aging shows puzzling diversity: similar aging rates yet vastly different health outcomes. Our study of ~17,500 people revealed a health-promoting trait (more common in women) linked to strong i....

Computer scientists and bioinformaticians address four key questions to help rookie coders to make the right choice.

Mitochondria serve as central hubs in cellular metabolism by sensing, integrating, and responding to metabolic demands. This integrative function is a…

Pathway analysis, originally developed for gene expression data, has been adapted for metabolomics. However, owing to the unique characteristics and constraints of metabolites compared with genes, pat...

Researchers are studying why the energy factories are moving between cells and whether the process can be harnessed to treat cancer and other diseases.

T cell priming is characterized by an initial activation phase that involves stable interactions with dendritic cells (DCs). How activated T cells receive the paracrine signals required for their diff...

MASLD is a growing global health concern. Here, the authors define a senescent hepatocyte gene signature (SHGS), demonstrate its clinical relevance, and identify senolytic therapies that selectively e...

Nature - Hundreds of cubes of human brain tissue help scientists to chart the energy-making capabilities of various brain regions.

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A new study identifies a mechanism by which Elovl1 deletion disrupts the canonical feedback inhibition of cholesterol synthesis in T cells. By fundamentally rewiring cholesterol metabolism, Elovl1-dep...

Nature Metabolism - The cyclic metabolic switching theory of intermittent fasting

The authors present a computational framework that leverages mechanical force inference and spatial transcriptomics to enable analyses of the interplay between the transcriptomic and mechanical state.

Report finds all 50 states reap gains in patient health, job creation, research resources, business development.

Nature - An amyloid protein targeted by Alzheimer’s disease therapies seems to be involved in normal mental decline.

Browse the list of placements available to undergraduate students wanting to work alongside RTPs in Summer 2025.

University management is courting a death spiral, where cuts in the name of sustainability actually undermine that which they are meant to save.

We are pleased to announce that 63 exceptional research projects have been selected at the autumn 2024 Research Awards open call.

T cell therapies for cancer currently rely on extensive in vitro expansion in hypermetabolic conditions. Frisch et al. demonstrate that T cells grown in vitro perform extensive aerobic glycolysis. Rer...

Deciphering the complex interplay between neuronal activity and mitochondrial function is pivotal in understanding brain aging, a multifaceted process marked by declines in synaptic function and mitoc...