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Alice Adriaenssens

@adriaenssenslab.bsky.social

Neurocircuits of Obesity, Incretin signalling in the brain

Alice Adriaenssens @adriaenssenslab.bsky.social · 24/06/2025

Unbelievably proud of @nataliefigueredob.bsky.social for winning the prestigious Bogue Fellowship 🌟 She'll be heading across the pond to train with the @zknight.bsky.social lab for 3 months. Exciting things to come for this bright young scientist 🧠. @uclnpp.bsky.social @ccmnlondon.bsky.social

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Alice Adriaenssens @adriaenssenslab.bsky.social · 29/04/2025

It's a big week for GIPR pharmacology! Two great studies out in @natmetabolism.nature.com from Gutgesell et al (www.nature.com/articles/s42...) and Liu et al (www.nature.com/articles/s42...) revealing divergent neural mechanisms engaged by GIPR agonism vs antagonism. Commentary here: rdcu.be/ejPSA

nature.com

GIPR agonism and antagonism decrease body weight and food intake via different mechanisms in male mice - Nature Metabolism

This study, together with a companion manuscript, show that, in mice, weight loss as a result of GIP receptor antagonism requires, and potentiates, functional GLP-1 receptor signalling in the brain, e...

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