Reposted by Gautier FollainGuillaume Jacquemet @guijacquemet.bsky.social · 04/09/2026🚨New preprint alert 🚨 "Pancreatic cancer cells breach endothelial barriers through protrusion-driven invasion or endothelial retraction" www.biorxiv.org/content/10.6... 24917
Reposted by Gautier FollainNaël Osmani @naelosmani.bsky.social · 19/01/2026💥finally here💥. Our latest manuscript (@goetzjacky.bsky.social lab) is out in @natmater.nature.com. We show that cell viscosity drives the metastatic potential. A project handled by former PhD student Valentin Gensbittel, help from Zeynep Yesilata & many labmates! www.nature.com/articles/s41...nature.comCell viscosity influences haematogenous dissemination and metastatic extravasation of tumour cells - Nature MaterialsThe viscosity of tumour cells is shown to govern their ability to disseminate through the bloodstream and extravasate, establishing a key biomechanical factor of metastasis. 151
Reposted by Gautier FollainGuillaume Jacquemet @guijacquemet.bsky.social · 06/01/2026Delighted to share the latest paper from the lab "Fast label-free live imaging with FlowVision reveals key principles of cancer cell arrest on endothelial monolayers" Amazing work driven by @follainga.bsky.social with contributions from many. link.springer.com/article/10.1...link.springer.comFast label-free live imaging with FlowVision reveals key principles of cancer cell arrest on endothelial monolayers - The EMBO JournalThe rapid, transient, and unpredictable nature of interactions between circulating cells and the endothelium challenges the investigation of these events under flow conditions. Here, we developed an i... 14912
Reposted by Gautier FollainIvaska Lab @ivaskalab.bsky.social · 26/05/2025Our newest paper is out in NCB. @jrwconway.bsky.social designed a new FRET reporter, Illusia, to show the importance of integrin β1 phosphorylation dynamics in 3D invasion! Video: TNBC cells expressing Illusia with a Src (Saracatinib) or SHP2 (SHP099) inhibitor. www.nature.com/articles/s41... 04011
Reposted by Gautier FollainJames Conway @jrwconway.bsky.social · 26/05/2025New paper from @ivaskalab.bsky.social out now! 🍾 Watch how cancer cell adhesion dynamics are disrupted by inhibiting the phosphatase Shp2 - key to integrin β1 phosphorylation. Blocking Shp2 impairs adhesion and reduces invasion potential. 🎥👇 Read more at: www.nature.com/articles/s41... 12914
Gautier Follain @follainga.bsky.social · 30/04/2025Can't wait to be in Italy for GRS/GRC...! 🥶 Fibronectin, Integrins and Related Molecules www.grc.org/fibronectin-... I'll present our preprint and more on extravasation of PDACs. :) 130
Reposted by Gautier FollainGuillaume Jacquemet @guijacquemet.bsky.social · 24/03/2025We wrote a small Viewpoint for Molecular Oncology with @follainga.bsky.social @omkarjoshi.bsky.social Michal Dibus via EACR @helloeacr.bsky.social Time, the final frontier febs.onlinelibrary.wiley.com/doi/full/10.... Hope you find it interestingfebs.onlinelibrary.wiley.com 083
Reposted by Gautier FollainGuillaume Jacquemet @guijacquemet.bsky.social · 04/12/2024Trying something new: For our recent preprint: Fast label-free live imaging reveals key roles of flow dynamics and CD44-HA interaction in cancer cell arrest on endothelial monolayers www.biorxiv.org/content/10.1... I made an online presentation: www.beautiful.ai/player/-ODGe...beautiful.aiFast label-free live imaging reveals key roles of flow dynamics and CD44-HA interaction in cancer cell arrest on endothelial monolayersGet started with Beautiful.ai today. 44513
Reposted by Gautier FollainIvaska Lab @ivaskalab.bsky.social · 19/11/2024Introductory post on 🦋! We're a research group headed by Prof. Johanna Ivaska interested in understanding how integrins contribute to every step of cancer progression. We're located at the Turku Bioscience Center in Turku, Finland! Find out more about us and our interests here: ivaskalab.utu.fiivaskalab.utu.fiIvaska cell adhesion and cancer LabIntegrins, matrix, motility and mechanotransduction in cancer 26716