Reposted by Simon FrommSimone Mattei @simonemattei.bsky.social · 28/09/2026Very happy to share that Robert Prevedel and I have been appointed to jointly lead the EMBL Imaging Centre! Excited to work with our fantastic team to build on the Centre’s strong foundations and keep pushing microscopy, technology development, imaging services and image analysis forward! 0162
Reposted by Simon FrommRasmus Jensen @rasmusjensen.bsky.social · 25/09/2026🎉 Out today in Cell: the paper I've been looking forward to sharing for a long time 🎉 We used cryo-ET to find a molecular machine nobody knew existed on the surface of a minimal bacterium, and worked out what it does. 🧵(1/7) #TeamTomo #cryoET 1023193
Reposted by Simon Frommeurobioimaging.bsky.social @eurobioimaging.bsky.social · 23/09/2026#VirtualPub We are delighted to welcome Simone Mattei, EMBL Imaging Centre, for a talk on "Targeted cryo-Serial Lift Out for cellular structural biology." 🗓️ Friday, September 25 @ 13:00 CEST Register⤵️ www.eurobioimaging.eu/events/seria... 034
Reposted by Simon Frommsimon-alkema.bsky.social @simon-alkema.bsky.social · 17/09/2026Releasing TOMATO, the TOMogram Annotation TOol! A lightweight Python GUI for going through hundreds of cryo-ET tomograms. Flag what's in each one, grade its quality, and end up with a table you can filter and act on. github.com/alkemasimon/... 15824
Reposted by Simon FrommJuan Carlos De la Concepcion @delaconcepcionjc.bsky.social · 05/08/2026PLEASE SHARE! New job openings in my lab @zmbp-tuebingen.bsky.social. We have a broad interest into the mechanistic basis of how molecular complexes are rewired during cellular development in plants and during invasion by pathogens. 🌱🍄🔬 See details below 👇 #PlantSciJobs 274105
Reposted by Simon FrommSimone Mattei @simonemattei.bsky.social · 21/08/2026Join our team at EMBL Imaging Centre! We are looking for a Microscopy Specialist with strong expertise in advanced light microscopy to help develop and establish cutting-edge super-resolution cryo-light microscopy and cryo-CLEM workflows. Apply here: embl.wd103.myworkdayjobs.com/EMBL/job/Hei...embl.wd103.myworkdayjobs.comMicroscopy SpecialistYour role The Microscopy Specialist contributes to the delivery and continuous advancement of the EMBL Imaging Centre by providing specalist expertise in super-resolution cryo-light microscopy (Cryo-L... 01210
Reposted by Simon FrommGuenter Resch @nexperion.net · 18/06/2026Two more recordings from the #SerialEM Community Meeting 2026 are available on our channel at vimeo.com/serialem : * D. Bollschweiler & T. Schaefer - [...] A Multi-User Service Facility Perspective on SerialEM * P. Kirchweger - Advances in cryo-STET: from 3D-cryo-STET to 3.5D- and 4D-cryo-STETvimeo.comSerialEM Talks and TutorialsSerialEM is a widely-used program that supports several kinds of automated acquisition from transmission electron microscopes: tilt series, single particle data,… 023
Reposted by Simon FrommBiohub @biohub.org · 11/06/2026In a series of 3 papers and preprints, we’re thrilled to share with you the working laser phase plate. In collaboration with research led by Holger Müller at UC Berkeley, this is a huge innovation in imaging to make small and faint objects inside cells visible. bit.ly/4vK9LVn 15336
Reposted by Simon FrommAhmad Jomaa @jomaalab.bsky.social · 13/05/2026Excited to share our work uncovering SNOR, a ribosome-associated factor that promotes translation restart after dormancy published in Nature!! This was, as usual, a wonderful collaborative effort between our group and the Mattei Lab @simonemattei.bsky.social @embl.org www.nature.com/articles/s41... 514758
Simon Fromm @simonfromm.bsky.social · 11/05/2026New preprint🧊🔬Introducing LowDoseWizard—a guided SerialEM workflow for rapid, standardised cryo-TEM setup! Setting up low-dose can be slow & daunting, especially for new users. LowDoseWizard automates optics, camera, and alignment steps from minimal input — full setup in <15 min. #cryoEM #SerialEM 12710
Reposted by Simon FrommShyamal @shyamalm.bsky.social · 20/01/2026We are running the cryo-ET image processing workshop again this year! Come learn everything tomo: STA, segmentation, heterogeneity analysis from @baradlab.com @williamnwan.bsky.social and others! Apply! 02218
Reposted by Simon FrommCarsten Sachse @sachsegroup.bsky.social · 23/12/2025We are looking for a team leader to join the cryo-EM facility work at the new Ernst Ruska-Centre 2.0 at the Forschungszentrum Jülich. We have a series of microscopes used by (@irene-vercellino.bsky.social, Schröder, @sachsegroup.bsky.social) and external users. www.fz-juelich.de/de/karriere/...fz-juelich.deTeam Leader – Life Science Cryo-Electron Microscopy (Cryo-EM) FacilityErnst Ruska-Centre for Microscopy and Spectroscopy with Electrons (ER-C) at Forschungszentrum Jülich houses some of the world`s most advanced electron microscopes and tools for nanocharacterisation. U... 01614
Reposted by Simon FrommGuenter Resch @nexperion.net · 23/09/2025Happy to announce "Technical Innovations Using #SerialEM: A Community Meeting", a new format of hybrid meeting David Mastronarde and I are organizing in April 2026. For more info, a preliminary list of speakers, pre-registration etc. visit www.nexperion.net/semcm2026 05122
Reposted by Simon FrommJim Hurley @jimhurley.bsky.social · 20/09/2025Position available! Team @mito911.bsky.social needs a new scientific program manager to take over from legendary super-PM @doroteaartscience.bsky.social, who is moving on to bigger things. This is a Berkeley-based position. Apply at aprecruit.berkeley.edu/JPF05103. 098
Reposted by Simon FrommArjen Jakobi @cryotud.bsky.social · 08/09/2025Together with colleagues at the Dept. of Microsystems Engineering, we are looking for a PhD student to develop methods for femtoliter-scale sample dispensing in cryoEM sample preparation. edu.nl/h436k If you like interdisciplinary research & fascinating physics at ultrasmall scales, please apply! 068
Reposted by Simon FrommTypas Lab @typaslab.bsky.social · 30/07/2025Ready to lead pioneering research that bridges systems-level investigations of biological systems to molecular mechanism? The EMBL Molecular Systems Biology Unit in Heidelberg is hiring a Group Leader!embl.wd103.myworkdayjobs.comGroup Leader – Molecular Systems Biology UnitAre you ready to lead groundbreaking research in Molecular Systems Biology? Join us at EMBL! We are seeking a motivated scientist to lead an independent research group, addressing original biological ... 17278
Reposted by Simon FrommJim Hurley @jimhurley.bsky.social · 25/07/2025Structural and cell biology NPG publication two-fer today: lysosome signaling structural biology tinyurl.com/mt3uc96k with @robzonculab.bsky.social and mitophagy initiation tinyurl.com/3rpjyfjt with @martenslab.bsky.social @lazaroulab.bsky.social and @hummerlab.bsky.social 13713
Simon Fromm @simonfromm.bsky.social · 16/07/2025🔬 Autumn School on Single Particle Cryo-EM: From Sample to 3D Reconstruction 📅 06–10 October 2025 📍 EMBL Imaging Centre, Heidelberg (Germany) Join us this October at EMBL for a 5-day intensive autumn school, covering the full cryo-EM SPA pipeline. tinyurl.com/4sp5vd7r 030
Reposted by Simon FrommArjen Jakobi @cryotud.bsky.social · 22/05/2025We are happy to release LocScale2.0: a tool for context-aware, confidence-weighted cryoEM map optimisation. Taking two half maps as input, LcoScale-2.0 produces feature-enhanced maps along with a robust confidence score that guides objective map interpretation. cryotud.github.io/locscale/ 112238
Reposted by Simon FrommJim Hurley @jimhurley.bsky.social · 15/01/2025Scientific Director, Cal-Cryo. We are looking for an outstanding microscopist to run our cryo-EM facility (two Krioses and an Arctica), increase training, engagement, and collaboration on campus, expand our user base, and join our community of cutting edge cryo-EM researchers. tinyurl.com/ykasna3ptinyurl.comScientific Director, Cal-Cryo@QB3, UC Berkeley’s Cryo-EM FacilityUniversity of California, Berkeley is hiring. Apply now! 02226
Reposted by Simon FrommJim Hurley @jimhurley.bsky.social · 09/01/2025PhDs in biochemistry, structural biology, pharmacology, or similar, located in the US and with strong publication track records and a high motivation to solve Parkinson's, please send CV directly to me at jimhurley@berkeley.edu. Repost appreciated. 07056
Reposted by Simon FrommJim Hurley @jimhurley.bsky.social · 16/11/2024Proud of new work tinyurl.com/yhz4c6ry from the lab by Zhicheng (Chen) Cui using single-particle cryo-EM on liposomes to show how mTORC1 integrates nutrient and growth factor signaling at lysosomes, collab. w/ G. Napolitano,A. Esposito, and A. Ballabio. 819947
Reposted by Simon FrommGuenter Resch @nexperion.net · 12/11/2024Better late than never: no more excuses for losing essential #SerialEM configuration files - a video tutorial explaining file types, backup and restore strategies is now online at vimeo.com/1023251181vimeo.comBacking Up a SerialEM SetupThis is "Backing Up a SerialEM Setup" by SerialEM Tutorials on Vimeo, the home for high quality videos and the people who love them. 001
Reposted by Simon FrommLars-Anders Carlson @lacarlson.bsky.social · 11/11/2024Repost appreciated: Open #PhDposition in my group! Join us in Umeå, 🇸🇪 to uncover how arboviruses remodel the cellular interior. In situ #cryoET with great #virology and #biophysics collaborators. Customisable project. Application deadline 15 December. More info: www.carlsonlab.se/join/ 05045