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Simon Fromm

@simonfromm.bsky.social
93 followers 75 following 8 posts

Running and maintaining cryoTEMs for external service provision @EMBL Imaging Centre. Mainly SPA but also cryoET. SerialEM fan!

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Reposted by Simon Fromm
Simone Mattei @simonemattei.bsky.social · 28/09/2026
Very happy to share that Robert Prevedel and I have been appointed to jointly lead the EMBL Imaging Centre! Excited to work with our fantastic team to build on the Centre’s strong foundations and keep pushing microscopy, technology development, imaging services and image analysis forward!
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Rasmus Jensen @rasmusjensen.bsky.social · 25/09/2026
🎉 Out today in Cell: the paper I've been looking forward to sharing for a long time 🎉 We used cryo-ET to find a molecular machine nobody knew existed on the surface of a minimal bacterium, and worked out what it does. 🧵(1/7) #TeamTomo #cryoET
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eurobioimaging.bsky.social @eurobioimaging.bsky.social · 23/09/2026
#VirtualPub We are delighted to welcome Simone Mattei, EMBL Imaging Centre, for a talk on "Targeted cryo-Serial Lift Out for cellular structural biology."  🗓️ Friday, September 25 @ 13:00 CEST Register⤵️ www.eurobioimaging.eu/events/seria...
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Reposted by Simon Fromm
simon-alkema.bsky.social @simon-alkema.bsky.social · 17/09/2026
Releasing TOMATO, the TOMogram Annotation TOol! A lightweight Python GUI for going through hundreds of cryo-ET tomograms. Flag what's in each one, grade its quality, and end up with a table you can filter and act on. github.com/alkemasimon/...
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Juan Carlos De la Concepcion @delaconcepcionjc.bsky.social · 05/08/2026
PLEASE SHARE! New job openings in my lab @zmbp-tuebingen.bsky.social. We have a broad interest into the mechanistic basis of how molecular complexes are rewired during cellular development in plants and during invasion by pathogens. 🌱🍄🔬 See details below 👇 #PlantSciJobs
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Simone Mattei @simonemattei.bsky.social · 21/08/2026
Join our team at EMBL Imaging Centre! We are looking for a Microscopy Specialist with strong expertise in advanced light microscopy to help develop and establish cutting-edge super-resolution cryo-light microscopy and cryo-CLEM workflows. Apply here: embl.wd103.myworkdayjobs.com/EMBL/job/Hei...
embl.wd103.myworkdayjobs.com
Microscopy Specialist
Your role The Microscopy Specialist contributes to the delivery and continuous advancement of the EMBL Imaging Centre by providing specalist expertise in super-resolution cryo-light microscopy (Cryo-L...
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Guenter Resch @nexperion.net · 18/06/2026
Two more recordings from the #SerialEM Community Meeting 2026 are available on our channel at vimeo.com/serialem : * D. Bollschweiler & T. Schaefer - [...] A Multi-User Service Facility Perspective on SerialEM * P. Kirchweger - Advances in cryo-STET: from 3D-cryo-STET to 3.5D- and 4D-cryo-STET
vimeo.com
SerialEM Talks and Tutorials
SerialEM is a widely-used program that supports several kinds of automated acquisition from transmission electron microscopes: tilt series, single particle data,…
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Reposted by Simon Fromm
Biohub @biohub.org · 11/06/2026
In a series of 3 papers and preprints, we’re thrilled to share with you the working laser phase plate. In collaboration with research led by Holger Müller at UC Berkeley, this is a huge innovation in imaging to make small and faint objects inside cells visible. bit.ly/4vK9LVn
Waves of laser light coming from four different directions and meeting in the middle brightly inside the cavity of the laser phase plate
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Ahmad Jomaa @jomaalab.bsky.social · 13/05/2026
Excited to share our work uncovering SNOR, a ribosome-associated factor that promotes translation restart after dormancy published in Nature!! This was, as usual, a wonderful collaborative effort between our group and the Mattei Lab @simonemattei.bsky.social @embl.org www.nature.com/articles/s41...
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Simon Fromm @simonfromm.bsky.social · 11/05/2026
New preprint🧊🔬Introducing LowDoseWizard—a guided SerialEM workflow for rapid, standardised cryo-TEM setup! Setting up low-dose can be slow & daunting, especially for new users. LowDoseWizard automates optics, camera, and alignment steps from minimal input — full setup in <15 min. #cryoEM #SerialEM
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Shyamal @shyamalm.bsky.social · 20/01/2026
We are running the cryo-ET image processing workshop again this year! Come learn everything tomo: STA, segmentation, heterogeneity analysis from @baradlab.com @williamnwan.bsky.social and others! Apply!
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Carsten Sachse @sachsegroup.bsky.social · 23/12/2025
We are looking for a team leader to join the cryo-EM facility work at the new Ernst Ruska-Centre 2.0 at the Forschungszentrum Jülich. We have a series of microscopes used by (@irene-vercellino.bsky.social, Schröder, @sachsegroup.bsky.social) and external users. www.fz-juelich.de/de/karriere/...
fz-juelich.de
Team Leader – Life Science Cryo-Electron Microscopy (Cryo-EM) Facility
Ernst Ruska-Centre for Microscopy and Spectroscopy with Electrons (ER-C) at Forschungszentrum Jülich houses some of the world`s most advanced electron microscopes and tools for nanocharacterisation. U...
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Guenter Resch @nexperion.net · 23/09/2025
Happy to announce "Technical Innovations Using #SerialEM: A Community Meeting", a new format of hybrid meeting David Mastronarde and I are organizing in April 2026. For more info, a preliminary list of speakers, pre-registration etc. visit www.nexperion.net/semcm2026
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Jim Hurley @jimhurley.bsky.social · 20/09/2025
Position available! Team @mito911.bsky.social needs a new scientific program manager to take over from legendary super-PM @doroteaartscience.bsky.social, who is moving on to bigger things. This is a Berkeley-based position. Apply at aprecruit.berkeley.edu/JPF05103.
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Arjen Jakobi @cryotud.bsky.social · 08/09/2025
Together with colleagues at the Dept. of Microsystems Engineering, we are looking for a PhD student to develop methods for femtoliter-scale sample dispensing in cryoEM sample preparation. edu.nl/h436k If you like interdisciplinary research & fascinating physics at ultrasmall scales, please apply!
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Typas Lab @typaslab.bsky.social · 30/07/2025
Ready to lead pioneering research that bridges systems-level investigations of biological systems to molecular mechanism? The EMBL Molecular Systems Biology Unit in Heidelberg is hiring a Group Leader!
embl.wd103.myworkdayjobs.com
Group Leader – Molecular Systems Biology Unit
Are you ready to lead groundbreaking research in Molecular Systems Biology? Join us at EMBL! We are seeking a motivated scientist to lead an independent research group, addressing original biological ...
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Jim Hurley @jimhurley.bsky.social · 25/07/2025
Structural and cell biology NPG publication two-fer today: lysosome signaling structural biology tinyurl.com/mt3uc96k with @robzonculab.bsky.social and mitophagy initiation tinyurl.com/3rpjyfjt with @martenslab.bsky.social @lazaroulab.bsky.social and @hummerlab.bsky.social
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Simon Fromm @simonfromm.bsky.social · 16/07/2025
🔬 Autumn School on Single Particle Cryo-EM: From Sample to 3D Reconstruction 📅 06–10 October 2025 📍 EMBL Imaging Centre, Heidelberg (Germany) Join us this October at EMBL for a 5-day intensive autumn school, covering the full cryo-EM SPA pipeline. tinyurl.com/4sp5vd7r
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Arjen Jakobi @cryotud.bsky.social · 22/05/2025
We are happy to release LocScale2.0: a tool for context-aware, confidence-weighted cryoEM map optimisation. Taking two half maps as input, LcoScale-2.0 produces feature-enhanced maps along with a robust confidence score that guides objective map interpretation. cryotud.github.io/locscale/
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Jim Hurley @jimhurley.bsky.social · 15/01/2025
Scientific Director, Cal-Cryo. We are looking for an outstanding microscopist to run our cryo-EM facility (two Krioses and an Arctica), increase training, engagement, and collaboration on campus, expand our user base, and join our community of cutting edge cryo-EM researchers. tinyurl.com/ykasna3p
tinyurl.com
Scientific Director, Cal-Cryo@QB3, UC Berkeley’s Cryo-EM Facility
University of California, Berkeley is hiring. Apply now!
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Jim Hurley @jimhurley.bsky.social · 09/01/2025
PhDs in biochemistry, structural biology, pharmacology, or similar, located in the US and with strong publication track records and a high motivation to solve Parkinson's, please send CV directly to me at jimhurley@berkeley.edu. Repost appreciated.
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Jim Hurley @jimhurley.bsky.social · 16/11/2024
Proud of new work tinyurl.com/yhz4c6ry from the lab by Zhicheng (Chen) Cui using single-particle cryo-EM on liposomes to show how mTORC1 integrates nutrient and growth factor signaling at lysosomes, collab. w/ G. Napolitano,A. Esposito, and A. Ballabio.
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Guenter Resch @nexperion.net · 12/11/2024
Better late than never: no more excuses for losing essential #SerialEM configuration files - a video tutorial explaining file types, backup and restore strategies is now online at vimeo.com/1023251181
vimeo.com
Backing Up a SerialEM Setup
This is "Backing Up a SerialEM Setup" by SerialEM Tutorials on Vimeo, the home for high quality videos and the people who love them.
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Reposted by Simon Fromm
Lars-Anders Carlson @lacarlson.bsky.social · 11/11/2024
Repost appreciated: Open #PhDposition in my group! Join us in Umeå, 🇸🇪 to uncover how arboviruses remodel the cellular interior. In situ #cryoET with great #virology and #biophysics collaborators. Customisable project. Application deadline 15 December. More info: www.carlsonlab.se/join/
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