Author summary Hantaviruses are ubiquitous rodent viruses and contain some of the most lethal known zoonotic viruses, including Andes virus (ANDV) and Hantaan virus (HTNV), with no FDA- or EMA-approve...

Laboratory Manager/Senior Scientist position in the Molecular Mucosal Immunology group at Oxford

Henipavirus nucleoprotein assemblies exist in different conformations, indicating temporary release of genome for RNA synthesis.

The ability of Salmonella Typhimurium to exploit macrophages as a niche for survival, replication, and dissemination is central to its pathogenesis. T…

Structural studies reveal how influenza virus switches between making new RNA genomes and exporting them from the host nucleus.

Researchers from across the University of Oxford were on the ground at COP30 in Belém, taking part in side events, presenting new research, and working with partners to support the negotiations and

Minister of health and social services Esperance Luvindao has confirmed an outbreak of the deadly Crimean-Congo haemorrhagic fever (CCHF) in Namibia, for which no vaccine or specific treatment exists.

A new COP30 report finds that rising temperatures, extreme weather, evolving pathogens and climate-driven migration are reshaping disease patterns

This map is updated weekly and visualizes outbreaks of nine childhood diseases in collaboration with the International Society for Infectious Diseases

Dr Jeremy Keown

Crimean-Congo Haemorrhagic Fever Virus (CCHFV) is found across Africa, Asia, and the Middle East where it can cause Haemorrhagic outbreaks with high case fatality rates. Central to the viral life cycl...

Combined upfront cost of the five-year Global Talent Visa and the Immigration Health Surcharge stands at £5,941

Nearly one-quarter of heatwaves would have been ‘virtually impossible’ without global warming — and can be attributed to the emissions of individual energy producers.

Borna disease virus 1 replicates and transcribes its negative sense RNA genome in the nucleus of infected cells. Here, the authors present the cryoEM structures of the large polymerase protein in comp...

Abstract. The ever-increasing amounts of plastic waste and greenhouse gas emissions worldwide threaten our environment. Biomedical laboratories across the

Scientists at The Pirbright Institute have taken a major step forward in tackling one of the world’s most dangerous viruses, the

Influenza viruses replicate and transcribe their genome in the context of a conserved ribonucleoprotein (RNP) complex. By integrating cryo–electron microscopy single-particle analysis and cryo–electro...

Viral polymerases rely on cellular cofactors to support efficient transcription of viral genes and replication of the viral genome. The RNA-dependent RNA polymerase of influenza virus, an orthomyxovir...

An executive order suspends the use of federal funds for certain experiments on pathogens with pandemic potential. Critics say low-risk science could be affected too.

Changes seen as a response to presidential directives on what research to fund

Researchers and administrators are exploring ways to restructure a rigid hierarchy that can breed power abuses.

YouTube video by Journeyman Pictures

Sala et al. report the first structural snapshot of the Nipah virus RNA-dependent RNA polymerase in the actively elongating state, uncovering key mechanisms of RNA synthesis by non-segmented negative ...

US President Donald Trump is taking a wrecking ball to science and to international institutions. The global research community must take a stand against these attacks.

Roughly 6,000 readers answered our poll, with many declaring that Bluesky was nicer, kinder and less antagonistic to science than X.

Cell-to-cell heterogeneity is a common feature of viral infection that can generate enormous complexity, complicating understanding of infection progression and interpretation of differences between v...

imageimageThe RNA polymerase complex of the Nipah virus is responsible for both replication and transcription of the viral RNA genome. This study elucidates the structure of the RNA polymerase in comp...

Author summary Hantaviruses are widely distributed viruses that can undergo zoonosis where they cause severe disease in humans. Old World hantaviruses, found predominantly in Asia and Europe, can caus...